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The map label for this gene is cvgSY [C]

Identifier: 21242421

GI number: 21242421

Start: 1930088

End: 1932160

Strand: Direct

Name: cvgSY [C]

Synonym: XAC1672

Alternate gene names: 21242421

Gene position: 1930088-1932160 (Clockwise)

Preceding gene: 21242420

Following gene: 21242436

Centisome position: 37.29

GC content: 65.75

Gene sequence:

>2073_bases
TTGACTATCTGTGACGCGGACGGCTCCATCGTTCATATCATCGCGCCGTTCGGACGCGATGCGCAGAGCATTGCCGGCAT
CGTTGGCGAACGCGGGCTAGCGCGCCGGGTCCATGCCACGCTGGACGCGCTGGCGGGCGACCTGCACGATGGTTCCGGCG
TGGTGGTCCTGACCGAAGAAGCGATCCGCGGCGACCTGCATGCGTTGTCGCACATCCTGCAAGGCCAGCAGGCCTGGTCG
GACATTCCGTTCGTGTTGTTGCGCACGCCGCGGGGTGCGCACAACCGCCGGCAGGTGCGTCTGCCGGCCGAGATGACCAA
CGTCATCGAGTTGGAGCGGCCGCTGAGCTCGGCCTCGTTGCTGAGCGCCATCTCCACCGCGTTGCGCGCACGGCAGAAGC
AGTTCGTCATCCGCGACCAGCTGGCGCAGTTGGCCGAAAGCCGCACCGCGCTGGCGCAGAGCGAGGCCGAACTGCGCCGG
GTGACCGATGCGCTGCCGGTGCTGATCGCTTTCATCGACAAGAACTTGGTGTACCGCTTTGCCAATCGTTCTTACGAAGA
CTGGATTGGTGTGCCGCCTTCCAACGTGATCGGGCGGCCGTTGGCGGATGTGGTCGGGCCTGCGGTGGTTCAAGAACGCC
GCGCCTGGATCGAGGCCGCGTTGGCCGGTCAGACGTTGACCATTGAAACCAGCTGGCCGCATGCCGATGGCCGCCGCCGC
GATGCGGAAATCCGCTACATGCCGCGCTTTGATGCGGACGGCAAGGTGGATGGATTCCATGTGTTCGCCACCGATGTGAC
CACACGTGCGCTGGCGCTGGAATCGATCCAGCAACAGGCCAACCTGCTGGAGGTCAAGGTGGCCGAGCGGACCGCCGAGT
TGCAACAGCAGATGCTGGCGCGCGAATCCAGCGAAGCGGCGCTGCGCCAGGCGCAGAAGATGGAAGCGGTAGGCCAGCTT
ACCGGTGGCATCGCACACGATTTCAACAACATGCTCACCGGCATCTTGTCTGCGCTGGATCTGGCGCGGCTGCGCATCGA
CCAGGGGCGCACCGAAGGGCTGGGCCGCTTTCTGGATGTGGCCTCCGCCTCGGCATTGCGCGCAGCTGCGCTCACCCAGC
GCCTGCTGGCATTCTCGCGGCGTCAGTCGCTACAGGCGCGGGATCTGCAGTTGAACGATCTGGTGGCGTCGTTGCAGGAG
TTGCTGGCGCGCACGTTGGGCGAATCGGTGCGTCTGGAGATCGATCTGTGTGCGGAACTGCCGCAGGCATACGTTGACGA
AAATCAGCTGGAAAGCGCACTGATCAATCTGGCCATCAACGCCCGCGATGCCATGCCCGACGGCGGGCAGCTGCGTATCG
CAACCCGGCAGCTGCAGGTGGAAGATCAGCCGCTGGAACTCGGCCGTGGCATTGCCTTGGCGCCGGGGCGTTACGTGGTG
GTGTCGGTCGCAGATACCGGGACCGGCATGCCCGCCGACGTGCTTGAACGCGTGTTCGAGCCGTTCTACACCACCAAGCC
GATCGGCCAGGGCACCGGCCTGGGCATGTCGATGATCTACGGCTTCATACAGCAGTCCAACGGCCAGGTCTGGGTGGAGT
CGCAGCCGGGCGCGGGCACCACGGTCAGCCTGTATCTGCCCGCCGGGGTTGCGGCGCAAACCGCAGTGCCGCAGACGCAG
AGCGATGCGGTGCTGGCAGGGCAGGGCCAGCAGGTGCTGGTGGTGGAAGACGACGAGCAGGTGCGGCTGCTGGTCACCGA
ACTGCTCAGCGAGCTGGGTTACCAGGCCGACGTGGTGGCCGACGCGGACGCGGCGCTGCCGATTCTTGCCTCGCCACGGC
GGATCGACCTGCTGGTCACCGATGTCGGCCTGCCGGGCCTCAACGGGCGCCAGTTGGCCGAGATCGCGCGGCAGTCGCGG
CGCGATCTGCCGGTGATCTTCATGACCGGCTACGCGGAAACGGCACGCGACCGTGGCGAATTTCTCGGCGAAGGCATGAG
CATGATCGCCAAGCCATTCACGCTGGGCGAGTTCAGCGGAAAGCTGCACGAAGTGCTGGGGCCTTCGGCCTGA

Upstream 100 bases:

>100_bases
AGCGGCCTTCAACTGAGTGAGCCGCTGGAGAAATTCCACGGCGTGTTGACCGGTACGCCGCAGTTTGTCGGAGACGACGG
CCCGTTGCTGGATCGTCCCG

Downstream 100 bases:

>100_bases
GTGCGGCTAACGCGATGTAGCGAGCCCGTTGAACGTGGGTGATCCATGGAAGCGGTGGGTACGAGTGGTTGCTTTCGCTC
TTGCGTGCCGACCTCGCCTG

Product: histidine kinase-response regulator hybrid protein

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 690; Mature: 689

Protein sequence:

>690_residues
MTICDADGSIVHIIAPFGRDAQSIAGIVGERGLARRVHATLDALAGDLHDGSGVVVLTEEAIRGDLHALSHILQGQQAWS
DIPFVLLRTPRGAHNRRQVRLPAEMTNVIELERPLSSASLLSAISTALRARQKQFVIRDQLAQLAESRTALAQSEAELRR
VTDALPVLIAFIDKNLVYRFANRSYEDWIGVPPSNVIGRPLADVVGPAVVQERRAWIEAALAGQTLTIETSWPHADGRRR
DAEIRYMPRFDADGKVDGFHVFATDVTTRALALESIQQQANLLEVKVAERTAELQQQMLARESSEAALRQAQKMEAVGQL
TGGIAHDFNNMLTGILSALDLARLRIDQGRTEGLGRFLDVASASALRAAALTQRLLAFSRRQSLQARDLQLNDLVASLQE
LLARTLGESVRLEIDLCAELPQAYVDENQLESALINLAINARDAMPDGGQLRIATRQLQVEDQPLELGRGIALAPGRYVV
VSVADTGTGMPADVLERVFEPFYTTKPIGQGTGLGMSMIYGFIQQSNGQVWVESQPGAGTTVSLYLPAGVAAQTAVPQTQ
SDAVLAGQGQQVLVVEDDEQVRLLVTELLSELGYQADVVADADAALPILASPRRIDLLVTDVGLPGLNGRQLAEIARQSR
RDLPVIFMTGYAETARDRGEFLGEGMSMIAKPFTLGEFSGKLHEVLGPSA

Sequences:

>Translated_690_residues
MTICDADGSIVHIIAPFGRDAQSIAGIVGERGLARRVHATLDALAGDLHDGSGVVVLTEEAIRGDLHALSHILQGQQAWS
DIPFVLLRTPRGAHNRRQVRLPAEMTNVIELERPLSSASLLSAISTALRARQKQFVIRDQLAQLAESRTALAQSEAELRR
VTDALPVLIAFIDKNLVYRFANRSYEDWIGVPPSNVIGRPLADVVGPAVVQERRAWIEAALAGQTLTIETSWPHADGRRR
DAEIRYMPRFDADGKVDGFHVFATDVTTRALALESIQQQANLLEVKVAERTAELQQQMLARESSEAALRQAQKMEAVGQL
TGGIAHDFNNMLTGILSALDLARLRIDQGRTEGLGRFLDVASASALRAAALTQRLLAFSRRQSLQARDLQLNDLVASLQE
LLARTLGESVRLEIDLCAELPQAYVDENQLESALINLAINARDAMPDGGQLRIATRQLQVEDQPLELGRGIALAPGRYVV
VSVADTGTGMPADVLERVFEPFYTTKPIGQGTGLGMSMIYGFIQQSNGQVWVESQPGAGTTVSLYLPAGVAAQTAVPQTQ
SDAVLAGQGQQVLVVEDDEQVRLLVTELLSELGYQADVVADADAALPILASPRRIDLLVTDVGLPGLNGRQLAEIARQSR
RDLPVIFMTGYAETARDRGEFLGEGMSMIAKPFTLGEFSGKLHEVLGPSA
>Mature_689_residues
TICDADGSIVHIIAPFGRDAQSIAGIVGERGLARRVHATLDALAGDLHDGSGVVVLTEEAIRGDLHALSHILQGQQAWSD
IPFVLLRTPRGAHNRRQVRLPAEMTNVIELERPLSSASLLSAISTALRARQKQFVIRDQLAQLAESRTALAQSEAELRRV
TDALPVLIAFIDKNLVYRFANRSYEDWIGVPPSNVIGRPLADVVGPAVVQERRAWIEAALAGQTLTIETSWPHADGRRRD
AEIRYMPRFDADGKVDGFHVFATDVTTRALALESIQQQANLLEVKVAERTAELQQQMLARESSEAALRQAQKMEAVGQLT
GGIAHDFNNMLTGILSALDLARLRIDQGRTEGLGRFLDVASASALRAAALTQRLLAFSRRQSLQARDLQLNDLVASLQEL
LARTLGESVRLEIDLCAELPQAYVDENQLESALINLAINARDAMPDGGQLRIATRQLQVEDQPLELGRGIALAPGRYVVV
SVADTGTGMPADVLERVFEPFYTTKPIGQGTGLGMSMIYGFIQQSNGQVWVESQPGAGTTVSLYLPAGVAAQTAVPQTQS
DAVLAGQGQQVLVVEDDEQVRLLVTELLSELGYQADVVADADAALPILASPRRIDLLVTDVGLPGLNGRQLAEIARQSRR
DLPVIFMTGYAETARDRGEFLGEGMSMIAKPFTLGEFSGKLHEVLGPSA

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=556, Percent_Identity=24.1007194244604, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788549, Length=252, Percent_Identity=29.7619047619048, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1790436, Length=253, Percent_Identity=28.0632411067194, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1788713, Length=290, Percent_Identity=25.8620689655172, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87081816, Length=408, Percent_Identity=26.9607843137255, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1790300, Length=251, Percent_Identity=28.6852589641434, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI145693157, Length=256, Percent_Identity=25, Blast_Score=66, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=150, Percent_Identity=34, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 74708; Mature: 74577

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTICDADGSIVHIIAPFGRDAQSIAGIVGERGLARRVHATLDALAGDLHDGSGVVVLTEE
CEEECCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEHH
AIRGDLHALSHILQGQQAWSDIPFVLLRTPRGAHNRRQVRLPAEMTNVIELERPLSSASL
HHHHHHHHHHHHHCCHHHHCCCCEEEEECCCCCCCCCEEECCHHHHHHHHHHCCCCHHHH
LSAISTALRARQKQFVIRDQLAQLAESRTALAQSEAELRRVTDALPVLIAFIDKNLVYRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANRSYEDWIGVPPSNVIGRPLADVVGPAVVQERRAWIEAALAGQTLTIETSWPHADGRRR
HCCCHHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCC
DAEIRYMPRFDADGKVDGFHVFATDVTTRALALESIQQQANLLEVKVAERTAELQQQMLA
CCCEEEECCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RESSEAALRQAQKMEAVGQLTGGIAHDFNNMLTGILSALDLARLRIDQGRTEGLGRFLDV
HCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ASASALRAAALTQRLLAFSRRQSLQARDLQLNDLVASLQELLARTLGESVRLEIDLCAEL
HHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHC
PQAYVDENQLESALINLAINARDAMPDGGQLRIATRQLQVEDQPLELGRGIALAPGRYVV
HHHHCCHHHHHHHHHHHEEECCCCCCCCCEEEEEEEEEECCCCHHHHCCCEEECCCCEEE
VSVADTGTGMPADVLERVFEPFYTTKPIGQGTGLGMSMIYGFIQQSNGQVWVESQPGAGT
EEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCC
TVSLYLPAGVAAQTAVPQTQSDAVLAGQGQQVLVVEDDEQVRLLVTELLSELGYQADVVA
EEEEEECCCCHHHCCCCCCCCCEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEE
DADAALPILASPRRIDLLVTDVGLPGLNGRQLAEIARQSRRDLPVIFMTGYAETARDRGE
CCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHH
FLGEGMSMIAKPFTLGEFSGKLHEVLGPSA
HHHCCHHHHHCCCCCHHHCCHHHHHCCCCC
>Mature Secondary Structure 
TICDADGSIVHIIAPFGRDAQSIAGIVGERGLARRVHATLDALAGDLHDGSGVVVLTEE
EEECCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEHH
AIRGDLHALSHILQGQQAWSDIPFVLLRTPRGAHNRRQVRLPAEMTNVIELERPLSSASL
HHHHHHHHHHHHHCCHHHHCCCCEEEEECCCCCCCCCEEECCHHHHHHHHHHCCCCHHHH
LSAISTALRARQKQFVIRDQLAQLAESRTALAQSEAELRRVTDALPVLIAFIDKNLVYRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANRSYEDWIGVPPSNVIGRPLADVVGPAVVQERRAWIEAALAGQTLTIETSWPHADGRRR
HCCCHHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCC
DAEIRYMPRFDADGKVDGFHVFATDVTTRALALESIQQQANLLEVKVAERTAELQQQMLA
CCCEEEECCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RESSEAALRQAQKMEAVGQLTGGIAHDFNNMLTGILSALDLARLRIDQGRTEGLGRFLDV
HCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ASASALRAAALTQRLLAFSRRQSLQARDLQLNDLVASLQELLARTLGESVRLEIDLCAEL
HHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHC
PQAYVDENQLESALINLAINARDAMPDGGQLRIATRQLQVEDQPLELGRGIALAPGRYVV
HHHHCCHHHHHHHHHHHEEECCCCCCCCCEEEEEEEEEECCCCHHHHCCCEEECCCCEEE
VSVADTGTGMPADVLERVFEPFYTTKPIGQGTGLGMSMIYGFIQQSNGQVWVESQPGAGT
EEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCC
TVSLYLPAGVAAQTAVPQTQSDAVLAGQGQQVLVVEDDEQVRLLVTELLSELGYQADVVA
EEEEEECCCCHHHCCCCCCCCCEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEE
DADAALPILASPRRIDLLVTDVGLPGLNGRQLAEIARQSRRDLPVIFMTGYAETARDRGE
CCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHH
FLGEGMSMIAKPFTLGEFSGKLHEVLGPSA
HHHCCHHHHHCCCCCHHHCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA