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The map label for this gene is ltrA [H]

Identifier: 21242405

GI number: 21242405

Start: 1907171

End: 1908172

Strand: Direct

Name: ltrA [H]

Synonym: XAC1655

Alternate gene names: 21242405

Gene position: 1907171-1908172 (Clockwise)

Preceding gene: 21242403

Following gene: 21242409

Centisome position: 36.85

GC content: 66.27

Gene sequence:

>1002_bases
ATGCACGACCTGAATGACCTGTATTATTTCGCGATGGTGGTGGATCACGGCGGCTTTGCCGCTGCCGAGCGTGCGCTGGG
CATCCCCAAATCGCGCCTGAGCCGCCGCATCAGCCAGCTCGAGACCGACCTGGGCGTGCGCCTGTTGCAGCGCTCCACGC
GCCGTTTCGCGGTGACCGACGTCGGCACCAGCGTGCACCGGCACGCGCAAACCATGCTTGCCGAGGCCCAGGCCGCGCGC
GAGGTGGTGGATCGTCTCAGCGCCGAGCCGCGCGGTCTGGTACGTGTGAGCGTTCCTGTTTCGCTTGCGCAGATCCAGTT
GCCCAAGTTGTTGCCGGAATTCCTGGCCAAGTATCCCAAGGTGCGGCTGCAGCTCAATATCAGCAATCGCCGCGTGGATG
TCATCAACGAGGGTTACGACATTGCGCTGCGTGTGCGCTCGCGCCTGGACGACGACGGCAGCCTGGTGATGCGCAGCTTC
GGCCAGGTGCAGGAACTGCTGGTTGCCAGTCCCAAATATCTGGATCGCGCCGGGCGTCCCAAGGACCCCAGCGAGCTGGC
CAACCACACCACCATGAGCACCAGCGAAGACGAAGCGCATCAGCGCTGGGAGCTGCACGGCCCGAACGGCGAAATGCGCC
GCGTCGATCTGCAGCCACGGCTGGCCGGCTTCGACTTCCCGCTGCTGCAGTCGATGGCGCGCGACGGCTTCGGCATCACC
ATGCTGCCGGAAACCGTATGCGCCGAAGCGGTGCGGAGCGGCGAGCTGGAAGTGGTGTTGCCGCACTGGTCGCTGCCGCA
GGGCATCTGCCATGCCGTGTTCGCCTCGCGTCGCGGCCTGCTGCCGGCGGTGCGGGTGTTCATCGACTTCCTGGCCGAAC
ACCTGCCCCAGGAAATCGAACGCTCGCGCCTGGATTGCGGCGGCAATTGCGCCGAACTGGCGGAAAAGCTCAAGCGTGCC
ACCGGCACGGCGCCGCGCCTGGTGGTGGCCGAAGCGGGCTAA

Upstream 100 bases:

>100_bases
CAAGCGGCATCGCCGCGGAGGTGTGCAGCCTAGGTCGTTGCTCTGTCGGAATAAAGGTGATTAAATATCACTTATCGTTC
TATCCATGGATACATGCGCC

Downstream 100 bases:

>100_bases
GCGTCCGTGACGAAGCTGGCCAAGGCCTAGGTTGACGGCCGAGGCTGGCCGGCATGTTGTCTGGCAGTCCCCTTGCTGTT
CAGCAGTCAGTTCGCTTCAG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MHDLNDLYYFAMVVDHGGFAAAERALGIPKSRLSRRISQLETDLGVRLLQRSTRRFAVTDVGTSVHRHAQTMLAEAQAAR
EVVDRLSAEPRGLVRVSVPVSLAQIQLPKLLPEFLAKYPKVRLQLNISNRRVDVINEGYDIALRVRSRLDDDGSLVMRSF
GQVQELLVASPKYLDRAGRPKDPSELANHTTMSTSEDEAHQRWELHGPNGEMRRVDLQPRLAGFDFPLLQSMARDGFGIT
MLPETVCAEAVRSGELEVVLPHWSLPQGICHAVFASRRGLLPAVRVFIDFLAEHLPQEIERSRLDCGGNCAELAEKLKRA
TGTAPRLVVAEAG

Sequences:

>Translated_333_residues
MHDLNDLYYFAMVVDHGGFAAAERALGIPKSRLSRRISQLETDLGVRLLQRSTRRFAVTDVGTSVHRHAQTMLAEAQAAR
EVVDRLSAEPRGLVRVSVPVSLAQIQLPKLLPEFLAKYPKVRLQLNISNRRVDVINEGYDIALRVRSRLDDDGSLVMRSF
GQVQELLVASPKYLDRAGRPKDPSELANHTTMSTSEDEAHQRWELHGPNGEMRRVDLQPRLAGFDFPLLQSMARDGFGIT
MLPETVCAEAVRSGELEVVLPHWSLPQGICHAVFASRRGLLPAVRVFIDFLAEHLPQEIERSRLDCGGNCAELAEKLKRA
TGTAPRLVVAEAG
>Mature_333_residues
MHDLNDLYYFAMVVDHGGFAAAERALGIPKSRLSRRISQLETDLGVRLLQRSTRRFAVTDVGTSVHRHAQTMLAEAQAAR
EVVDRLSAEPRGLVRVSVPVSLAQIQLPKLLPEFLAKYPKVRLQLNISNRRVDVINEGYDIALRVRSRLDDDGSLVMRSF
GQVQELLVASPKYLDRAGRPKDPSELANHTTMSTSEDEAHQRWELHGPNGEMRRVDLQPRLAGFDFPLLQSMARDGFGIT
MLPETVCAEAVRSGELEVVLPHWSLPQGICHAVFASRRGLLPAVRVFIDFLAEHLPQEIERSRLDCGGNCAELAEKLKRA
TGTAPRLVVAEAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=291, Percent_Identity=30.2405498281787, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1789639, Length=295, Percent_Identity=29.8305084745763, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87081978, Length=299, Percent_Identity=28.7625418060201, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1789440, Length=296, Percent_Identity=26.3513513513513, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI145693193, Length=295, Percent_Identity=29.1525423728814, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787128, Length=294, Percent_Identity=25.5102040816327, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787589, Length=291, Percent_Identity=27.1477663230241, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082132, Length=299, Percent_Identity=26.0869565217391, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI157672245, Length=126, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788706, Length=261, Percent_Identity=26.4367816091954, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1787806, Length=175, Percent_Identity=31.4285714285714, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787601, Length=128, Percent_Identity=27.34375, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 37050; Mature: 37050

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDLNDLYYFAMVVDHGGFAAAERALGIPKSRLSRRISQLETDLGVRLLQRSTRRFAVTD
CCCHHHHEEEHHEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEH
VGTSVHRHAQTMLAEAQAAREVVDRLSAEPRGLVRVSVPVSLAQIQLPKLLPEFLAKYPK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCC
VRLQLNISNRRVDVINEGYDIALRVRSRLDDDGSLVMRSFGQVQELLVASPKYLDRAGRP
EEEEEEECCCEEEEECCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCC
KDPSELANHTTMSTSEDEAHQRWELHGPNGEMRRVDLQPRLAGFDFPLLQSMARDGFGIT
CCHHHHHHCCCCCCCCHHHHHCEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCEE
MLPETVCAEAVRSGELEVVLPHWSLPQGICHAVFASRRGLLPAVRVFIDFLAEHLPQEIE
ECHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
RSRLDCGGNCAELAEKLKRATGTAPRLVVAEAG
HHHCCCCCCHHHHHHHHHHHCCCCCEEEEECCC
>Mature Secondary Structure
MHDLNDLYYFAMVVDHGGFAAAERALGIPKSRLSRRISQLETDLGVRLLQRSTRRFAVTD
CCCHHHHEEEHHEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEH
VGTSVHRHAQTMLAEAQAAREVVDRLSAEPRGLVRVSVPVSLAQIQLPKLLPEFLAKYPK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCC
VRLQLNISNRRVDVINEGYDIALRVRSRLDDDGSLVMRSFGQVQELLVASPKYLDRAGRP
EEEEEEECCCEEEEECCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCC
KDPSELANHTTMSTSEDEAHQRWELHGPNGEMRRVDLQPRLAGFDFPLLQSMARDGFGIT
CCHHHHHHCCCCCCCCHHHHHCEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCEE
MLPETVCAEAVRSGELEVVLPHWSLPQGICHAVFASRRGLLPAVRVFIDFLAEHLPQEIE
ECHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
RSRLDCGGNCAELAEKLKRATGTAPRLVVAEAG
HHHCCCCCCHHHHHHHHHHHCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]