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The map label for this gene is mip [H]

Identifier: 21242335

GI number: 21242335

Start: 1831402

End: 1832100

Strand: Direct

Name: mip [H]

Synonym: XAC1585

Alternate gene names: 21242335

Gene position: 1831402-1832100 (Clockwise)

Preceding gene: 21242331

Following gene: 21242336

Centisome position: 35.39

GC content: 65.24

Gene sequence:

>699_bases
ATGAAGTTGCGTTCTATCGCGGTCGCCGTGGCGGCCCTGGCCCTGACGGGCAATGCACTGGCCCAGGACACGACGTCCGA
GAAGGGCAAGTTGAGCTATTACTTCGGCTACGACTACGGCAACAATCTTGCCGAGCTCACCGGCCGCGGCGAGCAGCTCG
ACATCAACTCGGTGGTAAAGGGGCTGCAGGACGCCTATGCCAAGAAGCAGCCGGCGATCACTGCCGACCAGCTGAAGCCG
GCGGTTGAAGCGTTCCAGAAGCGCGAGCAGGGCCGTGCCCAGCAGGCCAAGGCCGAGTACGACAAGGCCGCTGCGGCCAA
CAAGACCAAGAGCGACGCGTTCCTGGCCAAGAACAAGAGCACCGCCGGCGTGCAGACGCTGCCGAGCGGCGTGCAGTACC
GCGTGATCGAAGCCGGCAAGGGCGCCAAGCCGACCCAGGCCAGCACCGTGCAGCTGGAAGTGGCCGGTCCATTCCCGTTC
GGCGACCGCGAGAAGGCACGTCCGGCGCAGCAGATCCCGGCCATCAAGGTCAGCGAGGTCGAAATGCAGGCCATGCGCGA
CACGCTGCTGCAAATGCCGGCCGGCTCGAAGTGGGAAGTGACCCTGCCGCCGGAAAAGGCCTACGGCGCCGATCCGCGTA
CCCCGTTCCCGCCGAACGTGGCTGTGCAGTTCGAGATCAAGCTGGTCAGCGTCAAGTAA

Upstream 100 bases:

>100_bases
GCTTTCGCGATAAGTAGCGGTTCGGTATCGCGGCCGTTATCCTAGCGCGTCATCTCAGGCGGCAGACCCGTCCTGTGCCA
CCACCCTGGAGAATTGTTTG

Downstream 100 bases:

>100_bases
TTGCACGCGATGGTGCTGCGATAACGCCGGCCACCAGGCCGGCGTTGTCGTTTTGGTCTGGCGATTGTCTGAAGAGAGCG
ATGCAACGATGCAGCGGCCG

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Macrophage infectivity potentiator; Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MKLRSIAVAVAALALTGNALAQDTTSEKGKLSYYFGYDYGNNLAELTGRGEQLDINSVVKGLQDAYAKKQPAITADQLKP
AVEAFQKREQGRAQQAKAEYDKAAAANKTKSDAFLAKNKSTAGVQTLPSGVQYRVIEAGKGAKPTQASTVQLEVAGPFPF
GDREKARPAQQIPAIKVSEVEMQAMRDTLLQMPAGSKWEVTLPPEKAYGADPRTPFPPNVAVQFEIKLVSVK

Sequences:

>Translated_232_residues
MKLRSIAVAVAALALTGNALAQDTTSEKGKLSYYFGYDYGNNLAELTGRGEQLDINSVVKGLQDAYAKKQPAITADQLKP
AVEAFQKREQGRAQQAKAEYDKAAAANKTKSDAFLAKNKSTAGVQTLPSGVQYRVIEAGKGAKPTQASTVQLEVAGPFPF
GDREKARPAQQIPAIKVSEVEMQAMRDTLLQMPAGSKWEVTLPPEKAYGADPRTPFPPNVAVQFEIKLVSVK
>Mature_232_residues
MKLRSIAVAVAALALTGNALAQDTTSEKGKLSYYFGYDYGNNLAELTGRGEQLDINSVVKGLQDAYAKKQPAITADQLKP
AVEAFQKREQGRAQQAKAEYDKAAAANKTKSDAFLAKNKSTAGVQTLPSGVQYRVIEAGKGAKPTQASTVQLEVAGPFPF
GDREKARPAQQIPAIKVSEVEMQAMRDTLLQMPAGSKWEVTLPPEKAYGADPRTPFPPNVAVQFEIKLVSVK

Specific function: Essential virulence factor associated with macrophage infectivity. Exhibits PPIase activity [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI87082390, Length=202, Percent_Identity=32.1782178217822, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789745, Length=207, Percent_Identity=29.4685990338164, Blast_Score=74, Evalue=9e-15,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008104
- InterPro:   IPR001179
- InterPro:   IPR000774 [H]

Pfam domain/function: PF00254 FKBP_C; PF01346 FKBP_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 24956; Mature: 24956

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRSIAVAVAALALTGNALAQDTTSEKGKLSYYFGYDYGNNLAELTGRGEQLDINSVVK
CCHHHHHHHHHHHHHCCCHHHCCCCCCCCCEEEEEECCCCCCHHHHCCCCCEECHHHHHH
GLQDAYAKKQPAITADQLKPAVEAFQKREQGRAQQAKAEYDKAAAANKTKSDAFLAKNKS
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCC
TAGVQTLPSGVQYRVIEAGKGAKPTQASTVQLEVAGPFPFGDREKARPAQQIPAIKVSEV
CCCHHHCCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCHHCCHHHHCCCEEEHHH
EMQAMRDTLLQMPAGSKWEVTLPPEKAYGADPRTPFPPNVAVQFEIKLVSVK
HHHHHHHHHHHCCCCCEEEEECCCHHHCCCCCCCCCCCCEEEEEEEEEEEEC
>Mature Secondary Structure
MKLRSIAVAVAALALTGNALAQDTTSEKGKLSYYFGYDYGNNLAELTGRGEQLDINSVVK
CCHHHHHHHHHHHHHCCCHHHCCCCCCCCCEEEEEECCCCCCHHHHCCCCCEECHHHHHH
GLQDAYAKKQPAITADQLKPAVEAFQKREQGRAQQAKAEYDKAAAANKTKSDAFLAKNKS
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCC
TAGVQTLPSGVQYRVIEAGKGAKPTQASTVQLEVAGPFPFGDREKARPAQQIPAIKVSEV
CCCHHHCCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCHHCCHHHHCCCEEEHHH
EMQAMRDTLLQMPAGSKWEVTLPPEKAYGADPRTPFPPNVAVQFEIKLVSVK
HHHHHHHHHHHCCCCCEEEEECCCHHHCCCCCCCCCCCCEEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA