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The map label for this gene is cynT [H]

Identifier: 21242330

GI number: 21242330

Start: 1826901

End: 1827581

Strand: Direct

Name: cynT [H]

Synonym: XAC1580

Alternate gene names: 21242330

Gene position: 1826901-1827581 (Clockwise)

Preceding gene: 21242322

Following gene: 21242331

Centisome position: 35.3

GC content: 63.73

Gene sequence:

>681_bases
ATGGAAAGTTTGCTAGAAGGTTTTCGTCATTTCCGTAAGGAAGTCTATCCGCGCCAGAGTGCGCGCTTTCAGGAGTTGGC
GGGCGGCCAGAGCCCGCATACGCTGTTCATCACCTGCGCAGATTCGCGCGTCATGCCGGAGCTGATCTTCTCCGCACAGC
CAGGCGAACTGTTCGTCTATCGCAATATCGGCAATGTGGTGCCGCCTTACTCTCAGCACGTCAGCGGCGTGGTGGCGGCG
ATCGAATACGCCATCGCTGTGCTGGGCGTGCGGCACATCGTGATCTGCGGGCATACCGACTGTGGCGCGATGAAGGCCGT
GCTCAAGCCGGAGTCGCTGGAAGACGTGCCCTCCGTGGCAGCGTGGCTCAAGCACACCGATGCGGCGCGTCATGTCACCG
CGCATCACGGGCACGATCCACAGAGCCCGGATGCGCTGAACTGCATGACCGAAGAGAACGTGGTCTCGCAGCTGGACCAT
CTGCGCACGCAGCCGGTGGTGGCAGCGCGCCTGGCGGCAGGCACCTTGCGCATCCACGGCTGGATCTACGACATCGCCCA
CGGGGAGATCCGCGCCTTCGATGCCGAGAAGGGTGGCTTCCGGCCACTGCTGGCCGAAAGCACCCCCGAAGCCACTCCAC
GCCCGCGACTGCAGCAAGTCGTGCGCGCTGAACTCGCCTGA

Upstream 100 bases:

>100_bases
CACCCGGTGCGTTCCGCGCCGGATTCCTACCTGATTTGTTTGTCTTTGCAATTCGCGGCGTGCGCCGCGGACTGCTATTC
GTTGCCTAGAGGAATCTCCC

Downstream 100 bases:

>100_bases
CGGAGCCTGCCATGAACACATCAGGTATCGGCGGATATTTCCGTCAGGGACTGTTTGGGCGTGATTTATTGGCGTCCGTA
GTGGTCTTCCTTGTCGCGCT

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MESLLEGFRHFRKEVYPRQSARFQELAGGQSPHTLFITCADSRVMPELIFSAQPGELFVYRNIGNVVPPYSQHVSGVVAA
IEYAIAVLGVRHIVICGHTDCGAMKAVLKPESLEDVPSVAAWLKHTDAARHVTAHHGHDPQSPDALNCMTEENVVSQLDH
LRTQPVVAARLAAGTLRIHGWIYDIAHGEIRAFDAEKGGFRPLLAESTPEATPRPRLQQVVRAELA

Sequences:

>Translated_226_residues
MESLLEGFRHFRKEVYPRQSARFQELAGGQSPHTLFITCADSRVMPELIFSAQPGELFVYRNIGNVVPPYSQHVSGVVAA
IEYAIAVLGVRHIVICGHTDCGAMKAVLKPESLEDVPSVAAWLKHTDAARHVTAHHGHDPQSPDALNCMTEENVVSQLDH
LRTQPVVAARLAAGTLRIHGWIYDIAHGEIRAFDAEKGGFRPLLAESTPEATPRPRLQQVVRAELA
>Mature_226_residues
MESLLEGFRHFRKEVYPRQSARFQELAGGQSPHTLFITCADSRVMPELIFSAQPGELFVYRNIGNVVPPYSQHVSGVVAA
IEYAIAVLGVRHIVICGHTDCGAMKAVLKPESLEDVPSVAAWLKHTDAARHVTAHHGHDPQSPDALNCMTEENVVSQLDH
LRTQPVVAARLAAGTLRIHGWIYDIAHGEIRAFDAEKGGFRPLLAESTPEATPRPRLQQVVRAELA

Specific function: Reversible Hydration Of Carbon Dioxide. Carbon Dioxide Formed In The Bicarbonate-Dependent Decomposition Of Cyanate By Cyanase (Cyns) Diffuses Out Of The Cell Faster Than It Would Be Hydrated To Bicarbonate, So The Apparent Function Of This Enzyme Is To C

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=213, Percent_Identity=44.6009389671362, Blast_Score=199, Evalue=1e-52,
Organism=Escherichia coli, GI1786318, Length=198, Percent_Identity=33.8383838383838, Blast_Score=99, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI25147564, Length=235, Percent_Identity=28.0851063829787, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI115532990, Length=246, Percent_Identity=26.0162601626016, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6324292, Length=172, Percent_Identity=31.9767441860465, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24645213, Length=241, Percent_Identity=26.5560165975104, Blast_Score=87, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 24848; Mature: 24848

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLLEGFRHFRKEVYPRQSARFQELAGGQSPHTLFITCADSRVMPELIFSAQPGELFVY
CHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHCCCCCCEEEE
RNIGNVVPPYSQHVSGVVAAIEYAIAVLGVRHIVICGHTDCGAMKAVLKPESLEDVPSVA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHCCCCCHHHHHHHH
AWLKHTDAARHVTAHHGHDPQSPDALNCMTEENVVSQLDHLRTQPVVAARLAAGTLRIHG
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCEEEEEE
WIYDIAHGEIRAFDAEKGGFRPLLAESTPEATPRPRLQQVVRAELA
EEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MESLLEGFRHFRKEVYPRQSARFQELAGGQSPHTLFITCADSRVMPELIFSAQPGELFVY
CHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHCCCCCCEEEE
RNIGNVVPPYSQHVSGVVAAIEYAIAVLGVRHIVICGHTDCGAMKAVLKPESLEDVPSVA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHCCCCCHHHHHHHH
AWLKHTDAARHVTAHHGHDPQSPDALNCMTEENVVSQLDHLRTQPVVAARLAAGTLRIHG
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCEEEEEE
WIYDIAHGEIRAFDAEKGGFRPLLAESTPEATPRPRLQQVVRAELA
EEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]