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The map label for this gene is moeB [H]

Identifier: 21242220

GI number: 21242220

Start: 1694052

End: 1694882

Strand: Direct

Name: moeB [H]

Synonym: XAC1467

Alternate gene names: 21242220

Gene position: 1694052-1694882 (Clockwise)

Preceding gene: 21242217

Following gene: 21242223

Centisome position: 32.73

GC content: 66.43

Gene sequence:

>831_bases
ATGAAAGCACAATGGCGTGAACGCTTTGCCGGTATCGACCGGCTGTACGGGGTCGGCACGGTCGAGCGCTTGTCGGCGTG
CCGCGTGGCGGTGGTCGGCATGGGTGGGGTGGGCTCGTGGGTGGTCGAGGCATTGGCACGCACCGGGGTGGGGCACATCC
GCCTGATCGATGCCGATGACGTGTGCGTGTCCAACACCAACCGGCAGCTGCCGGCGCTGGCCGGGCAGTACGGTCGCAAC
AAGGCGCGGGCGATGGCCGAGCGCTGCGTGGCGATCAACCCGGACATCGAAGCCGACGCGGTCGAGGCTTTCCTGACCTC
GGGCAATATCGAAACCTTGCTGGGTCAAGGCTTGGACCTGGTGATCGATGCCTGCGACAGCTTTCGGGTCAAGGTGGAAA
CCATCGCCTGGTGCCGTCGGCGCAAGTTGCCGCTGCTGACCGTGGGTGCGGCCGGTGGGCGCACCGACCCCACGCTGGTG
CGCGTGCGCGATGTCTCGCGCACCGAGCACGATGCGATGCTGGCGCTCACCCGCAAGAAGCTGCGCAGCGAATTCAATTT
CCCCAAGAACCCGCAGCGCTACTTCGGCGTGCCCGCGGTGTATTCGCTGGAAAACGTGAAATACCCGCAGGCCGATGGCA
GCGTCTGCGGCATCCGCCCACAGCTCGATGCCGATGCCACGCTCAAGCTCGATTGCGGGGCAGGGCTCGGTGCGGCCACG
CATATCACCGGCACCTTTGCATTCGTGGCGGTGGGCAAGGCGCTGGACATGTTGCTCAAGCCCAAGGCTGCGGTGGCGAT
GCCGGCAGCCGAGGCGGTTGCGGCGTCGTGA

Upstream 100 bases:

>100_bases
GACTGGGTGGGAGGCGGGGCGTGCATGAGGTGGCTCCTGGGACGCAACGTTCGTTGCGGCAGCGTGGGCGCGCCCTGAGC
GGGGCGCGTAAAATAGGCCG

Downstream 100 bases:

>100_bases
TGCGGCCTGCGCGCTGTCGTGCTGACCGCGCGCGCTAATGCGCACGCTGCGCTCAGTGCGGTAGGCCGAACAAGTTGCGT
GCGTTGGCCGACGTCTGCGC

Product: molybdopterin biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MKAQWRERFAGIDRLYGVGTVERLSACRVAVVGMGGVGSWVVEALARTGVGHIRLIDADDVCVSNTNRQLPALAGQYGRN
KARAMAERCVAINPDIEADAVEAFLTSGNIETLLGQGLDLVIDACDSFRVKVETIAWCRRRKLPLLTVGAAGGRTDPTLV
RVRDVSRTEHDAMLALTRKKLRSEFNFPKNPQRYFGVPAVYSLENVKYPQADGSVCGIRPQLDADATLKLDCGAGLGAAT
HITGTFAFVAVGKALDMLLKPKAAVAMPAAEAVAAS

Sequences:

>Translated_276_residues
MKAQWRERFAGIDRLYGVGTVERLSACRVAVVGMGGVGSWVVEALARTGVGHIRLIDADDVCVSNTNRQLPALAGQYGRN
KARAMAERCVAINPDIEADAVEAFLTSGNIETLLGQGLDLVIDACDSFRVKVETIAWCRRRKLPLLTVGAAGGRTDPTLV
RVRDVSRTEHDAMLALTRKKLRSEFNFPKNPQRYFGVPAVYSLENVKYPQADGSVCGIRPQLDADATLKLDCGAGLGAAT
HITGTFAFVAVGKALDMLLKPKAAVAMPAAEAVAAS
>Mature_276_residues
MKAQWRERFAGIDRLYGVGTVERLSACRVAVVGMGGVGSWVVEALARTGVGHIRLIDADDVCVSNTNRQLPALAGQYGRN
KARAMAERCVAINPDIEADAVEAFLTSGNIETLLGQGLDLVIDACDSFRVKVETIAWCRRRKLPLLTVGAAGGRTDPTLV
RVRDVSRTEHDAMLALTRKKLRSEFNFPKNPQRYFGVPAVYSLENVKYPQADGSVCGIRPQLDADATLKLDCGAGLGAAT
HITGTFAFVAVGKALDMLLKPKAAVAMPAAEAVAAS

Specific function: Unknown

COG id: COG1179

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Escherichia coli, GI1789177, Length=259, Percent_Identity=47.1042471042471, Blast_Score=245, Evalue=2e-66,
Organism=Escherichia coli, GI1787048, Length=130, Percent_Identity=35.3846153846154, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87082356, Length=131, Percent_Identity=32.0610687022901, Blast_Score=69, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6321790, Length=181, Percent_Identity=27.0718232044199, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322825, Length=201, Percent_Identity=32.3383084577114, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24660640, Length=152, Percent_Identity=29.6052631578947, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 29511; Mature: 29511

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAQWRERFAGIDRLYGVGTVERLSACRVAVVGMGGVGSWVVEALARTGVGHIRLIDADD
CCCHHHHHHHHHHHHHCCCHHHHHHHCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCC
VCVSNTNRQLPALAGQYGRNKARAMAERCVAINPDIEADAVEAFLTSGNIETLLGQGLDL
EEECCCCCCCCHHHHHHCCHHHHHHHHHHEEECCCCCHHHHHHHHHCCCHHHHHHCCHHE
VIDACDSFRVKVETIAWCRRRKLPLLTVGAAGGRTDPTLVRVRDVSRTEHDAMLALTRKK
EEECCCCCEEEHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHH
LRSEFNFPKNPQRYFGVPAVYSLENVKYPQADGSVCGIRPQLDADATLKLDCGAGLGAAT
HHHHCCCCCCCHHHCCCCCEEECCCCCCCCCCCCEECCCCCCCCCCEEEEECCCCCCCHH
HITGTFAFVAVGKALDMLLKPKAAVAMPAAEAVAAS
HHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHCCC
>Mature Secondary Structure
MKAQWRERFAGIDRLYGVGTVERLSACRVAVVGMGGVGSWVVEALARTGVGHIRLIDADD
CCCHHHHHHHHHHHHHCCCHHHHHHHCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCC
VCVSNTNRQLPALAGQYGRNKARAMAERCVAINPDIEADAVEAFLTSGNIETLLGQGLDL
EEECCCCCCCCHHHHHHCCHHHHHHHHHHEEECCCCCHHHHHHHHHCCCHHHHHHCCHHE
VIDACDSFRVKVETIAWCRRRKLPLLTVGAAGGRTDPTLVRVRDVSRTEHDAMLALTRKK
EEECCCCCEEEHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHH
LRSEFNFPKNPQRYFGVPAVYSLENVKYPQADGSVCGIRPQLDADATLKLDCGAGLGAAT
HHHHCCCCCCCHHHCCCCCEEECCCCCCCCCCCCEECCCCCCCCCCEEEEECCCCCCCHH
HITGTFAFVAVGKALDMLLKPKAAVAMPAAEAVAAS
HHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]