Click here to switch to the map view.

The map label for this gene is cspA [H]

Identifier: 21242217

GI number: 21242217

Start: 1692583

End: 1692798

Strand: Direct

Name: cspA [H]

Synonym: XAC1465

Alternate gene names: 21242217

Gene position: 1692583-1692798 (Clockwise)

Preceding gene: 21242214

Following gene: 21242220

Centisome position: 32.7

GC content: 54.63

Gene sequence:

>216_bases
ATGTCCAATATCGAACGCGAAAATGGTGTCGTGAAGTGGTTCAACGACGCCAAAGGCTTTGGATTCATCAGCCGCGAAAA
TGGCGAAGACGTCTTCGTGCATTTCCGCGCGATCCAGATCCAGGGCTTCAAGAGTCTCAAGGAAGGTCAGAAGGTCAGCT
TCACGGTCGTGCAAGGCCAGAAGGGCCTGCAGGCCGATGCAGTGCAGGTGGTCTGA

Upstream 100 bases:

>100_bases
GGTAGATCGTCTGATCCGCTACATCCTTGTACCTCGCTTCCTCCTTGCAATCACAGCCACCACCGCTAGTCCATCACAGT
GTCGTAGGGAGTCAGTCGAG

Downstream 100 bases:

>100_bases
GCCGGCTGCGCGGAGCGCGGTAGCCACGCAACAAAAAGGCCCGTCGCCGGGCCTTTTTGTTGCGTGGCGACTGTGTTGTC
GCGGCCGTTGCCGAAGGGCA

Product: major cold shock protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 71; Mature: 70

Protein sequence:

>71_residues
MSNIERENGVVKWFNDAKGFGFISRENGEDVFVHFRAIQIQGFKSLKEGQKVSFTVVQGQKGLQADAVQVV

Sequences:

>Translated_71_residues
MSNIERENGVVKWFNDAKGFGFISRENGEDVFVHFRAIQIQGFKSLKEGQKVSFTVVQGQKGLQADAVQVV
>Mature_70_residues
SNIERENGVVKWFNDAKGFGFISRENGEDVFVHFRAIQIQGFKSLKEGQKVSFTVVQGQKGLQADAVQVV

Specific function: Binds To And Stimulates The Transcription Of The CCAAT- Containing, Cold-Shock-Inducible Promoters Of The H-Ns And Gyra Proteins. Binds Also To The Inverted Repeat 5'-ATTGG-3'. [C]

COG id: COG1278

COG function: function code K; Cold shock proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CSD (cold-shock) domain [H]

Homologues:

Organism=Escherichia coli, GI1789979, Length=67, Percent_Identity=58.2089552238806, Blast_Score=77, Evalue=2e-16,
Organism=Escherichia coli, GI1786841, Length=69, Percent_Identity=57.9710144927536, Blast_Score=75, Evalue=6e-16,
Organism=Escherichia coli, GI1787107, Length=66, Percent_Identity=54.5454545454545, Blast_Score=75, Evalue=9e-16,
Organism=Escherichia coli, GI2367114, Length=69, Percent_Identity=55.0724637681159, Blast_Score=71, Evalue=1e-14,
Organism=Escherichia coli, GI1788126, Length=64, Percent_Identity=57.8125, Blast_Score=70, Evalue=2e-14,
Organism=Escherichia coli, GI1787839, Length=72, Percent_Identity=52.7777777777778, Blast_Score=69, Evalue=5e-14,
Organism=Escherichia coli, GI1787834, Length=72, Percent_Identity=54.1666666666667, Blast_Score=68, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019844
- InterPro:   IPR012156
- InterPro:   IPR011129
- InterPro:   IPR002059
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00313 CSD [H]

EC number: NA

Molecular weight: Translated: 7945; Mature: 7814

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS00352 COLD_SHOCK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNIERENGVVKWFNDAKGFGFISRENGEDVFVHFRAIQIQGFKSLKEGQKVSFTVVQGQ
CCCCCCCCCEEEEECCCCCCEEEECCCCCEEEEEEEEEEEECCCCCCCCCEEEEEEEECC
KGLQADAVQVV
CCCCCCEEEEC
>Mature Secondary Structure 
SNIERENGVVKWFNDAKGFGFISRENGEDVFVHFRAIQIQGFKSLKEGQKVSFTVVQGQ
CCCCCCCCEEEEECCCCCCEEEECCCCCEEEEEEEEEEEECCCCCCCCCEEEEEEEECC
KGLQADAVQVV
CCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]