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The map label for this gene is algU [H]

Identifier: 21242072

GI number: 21242072

Start: 1524062

End: 1524682

Strand: Direct

Name: algU [H]

Synonym: XAC1319

Alternate gene names: 21242072

Gene position: 1524062-1524682 (Clockwise)

Preceding gene: 21242070

Following gene: 21242073

Centisome position: 29.45

GC content: 62.64

Gene sequence:

>621_bases
ATGGCCGAAGTCGATACACCTCAGGAGCTGGACCTGGAACTGGTCCGGCGTGTGCAGCGCGGCGAAAGTGCGGCGTTCGA
TGTGCTGGTGCGCAAGTACCAGCATCGGATCGTTGCCTTGATCGGGCGCTACATCGCCGACTGGAGCGAATGCCAGGACG
TTGCCCAGGACACGTTCGTGCGCGCCTACCGCGCGATCAACAGTTTTCGGGGCGACGCCCAGTTCTATACCTGGCTGCAC
CGCATTGCCGTCAACACTGCCAAGAACCATCTGGTTGCGCACAACCGCCGCCCGCCCACCGACGACATCGAGATCAGCGA
TGCCGAACAATTCGATGGAGCGACACGGTTGCGCGACACCGATACCCCGGAGCGCGAATTGATGCGACAGGAGCTGGAAC
AAACGGTGATGCGCGCGGTCCAAGCGCTACCGGAAGAACTTCGGTTGGCCATCACCCTGCGCGAGGTGGAGGGCCTGAGC
TACGACGAAATCGCGCAAAAGATGGATTGCCCGATCGGAACGGTGCGCTCGCGCATCTTCCGGGCGCGCGAGGCCATCGA
CATCGAGCTGCGGCCTCTGCTGGAGACCGAAAGCGCTACCCGTGAGCGACACCGCGTATGA

Upstream 100 bases:

>100_bases
TACCCTGATGCGTGACGGTCGTACGGATCGGTATGAACTTTTCTTTTCAATGGCGGTCTCATTGCCCGACTTCGGTGGGC
TGACAGGAGTGCGGCCCGAC

Downstream 100 bases:

>100_bases
ACCAGAACTCTGCCATGTCCACCACCGACAAATTCGAACTTCACTATCGCCAGCAGCTGTCTGCGCTGGTCGACGGCGAA
TTGAGTGCCGACGAGTCGCG

Product: RNA polymerase sigma factor RpoE

Products: NA

Alternate protein names: Sigma-30 [H]

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MAEVDTPQELDLELVRRVQRGESAAFDVLVRKYQHRIVALIGRYIADWSECQDVAQDTFVRAYRAINSFRGDAQFYTWLH
RIAVNTAKNHLVAHNRRPPTDDIEISDAEQFDGATRLRDTDTPERELMRQELEQTVMRAVQALPEELRLAITLREVEGLS
YDEIAQKMDCPIGTVRSRIFRAREAIDIELRPLLETESATRERHRV

Sequences:

>Translated_206_residues
MAEVDTPQELDLELVRRVQRGESAAFDVLVRKYQHRIVALIGRYIADWSECQDVAQDTFVRAYRAINSFRGDAQFYTWLH
RIAVNTAKNHLVAHNRRPPTDDIEISDAEQFDGATRLRDTDTPERELMRQELEQTVMRAVQALPEELRLAITLREVEGLS
YDEIAQKMDCPIGTVRSRIFRAREAIDIELRPLLETESATRERHRV
>Mature_205_residues
AEVDTPQELDLELVRRVQRGESAAFDVLVRKYQHRIVALIGRYIADWSECQDVAQDTFVRAYRAINSFRGDAQFYTWLHR
IAVNTAKNHLVAHNRRPPTDDIEISDAEQFDGATRLRDTDTPERELMRQELEQTVMRAVQALPEELRLAITLREVEGLSY
DEIAQKMDCPIGTVRSRIFRAREAIDIELRPLLETESATRERHRV

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor regulates genes such as algD, involved in alginate biosynthesis [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=187, Percent_Identity=55.0802139037433, Blast_Score=228, Evalue=1e-61,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR014286
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 23960; Mature: 23829

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEVDTPQELDLELVRRVQRGESAAFDVLVRKYQHRIVALIGRYIADWSECQDVAQDTFV
CCCCCCCHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
RAYRAINSFRGDAQFYTWLHRIAVNTAKNHLVAHNRRPPTDDIEISDAEQFDGATRLRDT
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCC
DTPERELMRQELEQTVMRAVQALPEELRLAITLREVEGLSYDEIAQKMDCPIGTVRSRIF
CCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHH
RAREAIDIELRPLLETESATRERHRV
HHHHHHCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEVDTPQELDLELVRRVQRGESAAFDVLVRKYQHRIVALIGRYIADWSECQDVAQDTFV
CCCCCCHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
RAYRAINSFRGDAQFYTWLHRIAVNTAKNHLVAHNRRPPTDDIEISDAEQFDGATRLRDT
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCC
DTPERELMRQELEQTVMRAVQALPEELRLAITLREVEGLSYDEIAQKMDCPIGTVRSRIF
CCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHH
RAREAIDIELRPLLETESATRERHRV
HHHHHHCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8432708; 8378309; 7961421; 10984043; 7737518 [H]