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The map label for this gene is czcD [H]

Identifier: 21242070

GI number: 21242070

Start: 1520549

End: 1521514

Strand: Direct

Name: czcD [H]

Synonym: XAC1317

Alternate gene names: 21242070

Gene position: 1520549-1521514 (Clockwise)

Preceding gene: 21242069

Following gene: 21242072

Centisome position: 29.38

GC content: 65.42

Gene sequence:

>966_bases
ATGGGACACGACCACAACCACGCACCCAGCGAAATCCGTCACGAAGCGCCCTTGTGGTGGGCACTGGGGCTGACCGCCAC
CTTCCTGCTGGCAGAGATCGTCGGCGCATTCGTGACCAACAGCCTGGCGCTGCTGTCCGACGCTGCGCATATGGCCACCG
ACACCGTCGGACTGATGATTGCGCTGGTCGCGGTGCGCCTGAGCCGTCGCCCGGCCGACGCGCGTCGCACCTATGGCTAT
GTGCGGCTCGAAGCGCTTGGCGCATTGGCCAACGGCGCGCTGCTGTTCGCAGTCGGCGCCTATATCTTGTGGGAAGCCGC
GCAGCGCTTTCGCGCACCGCAGGACATCTCTTCCAGCGGCATGCTGTTGATCGCCGGCTTCGGCCTGGTGATCAATCTGG
TCGCGATGAAGCTGCTGCACGCCGGCAGCGGCGAAAGCCTCAACGTCAAGGGTGCCTATCTGGAGGTGTGGAGCGACATG
CTCGGCTCGGTGGCGGTGATCGTCGGTGCCTTGCTGATCCGCTGGACCGGCTGGCAATGGATCGACCCGGTGTTGGCCGT
GCTGATCGGCCTGTGGGTATTGCCGCGCACCTGGGTGCTGCTGCGCGAGGCGATCAACGTGTTGCTTGAAGGCGTGCCCA
AGGGGATCGACCTGGCCCAGGTGCAGCAGGCGCTGACCAGCCACCCTGGCGTCGAAGACGTGCACGACCTGCATGTGTGG
GCATTGGCCTCCAGCACGCCGGCGCTCACCGCGCACATCGTGGTCAACGAGGCCACCGACCGCGACCGTCTGCGTGACGC
GCTCGGCGCCCTGTTGCATGAGCGCTTCGATATCGCCCACGTCACCTTGCAGGTGGAAAGTGGCGACTGCGGTACTGAGC
CTTGCGGCACACCAAAGCCGGCTGCAGACGCTGGCCATGACGCGCACCATGAGCACGGTCATGCGCACGGGCATTCCCAT
CATTAA

Upstream 100 bases:

>100_bases
CCGCACGGCTCGCGTGATGTGATGTCATTACGCACAGGTGTAATAGTCTCCGCCATCGCGTGCGCCTAAGGTGCGCGCAT
TGCAGCAGGCCACGATATCC

Downstream 100 bases:

>100_bases
CGTCTGGTAGCAGCAGCTCGGCAGGTCATCAAATTAGCGTGGATCGACCGGCACAATCCACGGAAAGGGTCCGGCACTGG
CGCAACCTACCTAGCGCAAC

Product: cobalt-zinc-cadmium resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MGHDHNHAPSEIRHEAPLWWALGLTATFLLAEIVGAFVTNSLALLSDAAHMATDTVGLMIALVAVRLSRRPADARRTYGY
VRLEALGALANGALLFAVGAYILWEAAQRFRAPQDISSSGMLLIAGFGLVINLVAMKLLHAGSGESLNVKGAYLEVWSDM
LGSVAVIVGALLIRWTGWQWIDPVLAVLIGLWVLPRTWVLLREAINVLLEGVPKGIDLAQVQQALTSHPGVEDVHDLHVW
ALASSTPALTAHIVVNEATDRDRLRDALGALLHERFDIAHVTLQVESGDCGTEPCGTPKPAADAGHDAHHEHGHAHGHSH
H

Sequences:

>Translated_321_residues
MGHDHNHAPSEIRHEAPLWWALGLTATFLLAEIVGAFVTNSLALLSDAAHMATDTVGLMIALVAVRLSRRPADARRTYGY
VRLEALGALANGALLFAVGAYILWEAAQRFRAPQDISSSGMLLIAGFGLVINLVAMKLLHAGSGESLNVKGAYLEVWSDM
LGSVAVIVGALLIRWTGWQWIDPVLAVLIGLWVLPRTWVLLREAINVLLEGVPKGIDLAQVQQALTSHPGVEDVHDLHVW
ALASSTPALTAHIVVNEATDRDRLRDALGALLHERFDIAHVTLQVESGDCGTEPCGTPKPAADAGHDAHHEHGHAHGHSH
H
>Mature_320_residues
GHDHNHAPSEIRHEAPLWWALGLTATFLLAEIVGAFVTNSLALLSDAAHMATDTVGLMIALVAVRLSRRPADARRTYGYV
RLEALGALANGALLFAVGAYILWEAAQRFRAPQDISSSGMLLIAGFGLVINLVAMKLLHAGSGESLNVKGAYLEVWSDML
GSVAVIVGALLIRWTGWQWIDPVLAVLIGLWVLPRTWVLLREAINVLLEGVPKGIDLAQVQQALTSHPGVEDVHDLHVWA
LASSTPALTAHIVVNEATDRDRLRDALGALLHERFDIAHVTLQVESGDCGTEPCGTPKPAADAGHDAHHEHGHAHGHSHH

Specific function: Necessary for activation of the czc determinant [H]

COG id: COG1230

COG function: function code P; Co/Zn/Cd efflux system component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily [H]

Homologues:

Organism=Homo sapiens, GI52352805, Length=315, Percent_Identity=29.8412698412698, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI21361112, Length=304, Percent_Identity=29.9342105263158, Blast_Score=134, Evalue=8e-32,
Organism=Homo sapiens, GI289803013, Length=295, Percent_Identity=27.7966101694915, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI289803009, Length=295, Percent_Identity=27.7966101694915, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI289803007, Length=295, Percent_Identity=27.7966101694915, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI289803003, Length=295, Percent_Identity=27.7966101694915, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI64762489, Length=295, Percent_Identity=27.7966101694915, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI21359890, Length=319, Percent_Identity=27.5862068965517, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI14210520, Length=234, Percent_Identity=29.0598290598291, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI20070323, Length=315, Percent_Identity=26.6666666666667, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI52351208, Length=157, Percent_Identity=33.1210191082803, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI52352803, Length=136, Percent_Identity=39.7058823529412, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI222080086, Length=119, Percent_Identity=31.9327731092437, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI40255009, Length=119, Percent_Identity=31.9327731092437, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1786966, Length=280, Percent_Identity=43.2142857142857, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI1790349, Length=245, Percent_Identity=24.4897959183673, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17555794, Length=324, Percent_Identity=33.0246913580247, Blast_Score=174, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17555796, Length=313, Percent_Identity=33.5463258785943, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI193210990, Length=328, Percent_Identity=30.4878048780488, Blast_Score=164, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI32564488, Length=295, Percent_Identity=29.8305084745763, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17550442, Length=120, Percent_Identity=35, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17550440, Length=120, Percent_Identity=35, Blast_Score=77, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6320411, Length=173, Percent_Identity=30.0578034682081, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6323899, Length=128, Percent_Identity=40.625, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324892, Length=126, Percent_Identity=39.6825396825397, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24583858, Length=314, Percent_Identity=30.5732484076433, Blast_Score=145, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24656728, Length=323, Percent_Identity=28.7925696594427, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24656724, Length=323, Percent_Identity=28.7925696594427, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24656720, Length=323, Percent_Identity=28.7925696594427, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24656715, Length=323, Percent_Identity=28.7925696594427, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21357035, Length=323, Percent_Identity=28.7925696594427, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24584409, Length=151, Percent_Identity=33.112582781457, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI28574430, Length=151, Percent_Identity=33.112582781457, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24585900, Length=145, Percent_Identity=36.551724137931, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24585898, Length=145, Percent_Identity=36.551724137931, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24585896, Length=145, Percent_Identity=36.551724137931, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19921672, Length=145, Percent_Identity=36.551724137931, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24645863, Length=110, Percent_Identity=33.6363636363636, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 34511; Mature: 34380

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHDHNHAPSEIRHEAPLWWALGLTATFLLAEIVGAFVTNSLALLSDAAHMATDTVGLMI
CCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVAVRLSRRPADARRTYGYVRLEALGALANGALLFAVGAYILWEAAQRFRAPQDISSSG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
MLLIAGFGLVINLVAMKLLHAGSGESLNVKGAYLEVWSDMLGSVAVIVGALLIRWTGWQW
EEEEHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
IDPVLAVLIGLWVLPRTWVLLREAINVLLEGVPKGIDLAQVQQALTSHPGVEDVHDLHVW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHE
ALASSTPALTAHIVVNEATDRDRLRDALGALLHERFDIAHVTLQVESGDCGTEPCGTPKP
EEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCEEEEEEEEECCCCCCCCCCCCCC
AADAGHDAHHEHGHAHGHSHH
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GHDHNHAPSEIRHEAPLWWALGLTATFLLAEIVGAFVTNSLALLSDAAHMATDTVGLMI
CCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVAVRLSRRPADARRTYGYVRLEALGALANGALLFAVGAYILWEAAQRFRAPQDISSSG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
MLLIAGFGLVINLVAMKLLHAGSGESLNVKGAYLEVWSDMLGSVAVIVGALLIRWTGWQW
EEEEHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
IDPVLAVLIGLWVLPRTWVLLREAINVLLEGVPKGIDLAQVQQALTSHPGVEDVHDLHVW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHE
ALASSTPALTAHIVVNEATDRDRLRDALGALLHERFDIAHVTLQVESGDCGTEPCGTPKP
EEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCEEEEEEEEECCCCCCCCCCCCCC
AADAGHDAHHEHGHAHGHSHH
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]