Click here to switch to the map view.

The map label for this gene is surA

Identifier: 21241635

GI number: 21241635

Start: 1026195

End: 1027586

Strand: Reverse

Name: surA

Synonym: XAC0865

Alternate gene names: 21241635

Gene position: 1027586-1026195 (Counterclockwise)

Preceding gene: 21241636

Following gene: 21241634

Centisome position: 19.85

GC content: 65.66

Gene sequence:

>1392_bases
ATGACCAAGCCTTTCTCTGTTGTTCTCGCCTCGCTGCTGGCCATCACCAGCACGGTTTCGCCGTTGGCCTCGGCACAGCA
ATCCCAGCCGCTGGATCGCATCGCTGCCATCGTCGACGAAGACGTGGTGCTGCAGAGCGAGCTCGATCGCGCCGTACGCA
ACGTCAAGTCGCAGTACGCCGGTCGCGAAAACCAGCTGCCGCCAGACGATGTGCTGCAGCGCCAGGTCCTTGAGCGCTTG
GTGCTGGTCAAGTTGCAGGTCAGCCGCGCCGATGGCAACGGTATCCGCGTCAGCGACGAGGAGCTCAACCGCGCCATCGC
CAGCATCGCCCAGCAGAACGGCACGACCGTGGATGGCTTGCGCCAGAAGCTGGCGGCCGACGGCATGGGCTACGCCGATT
TCCGCGCATCGGTGCGCGACGAGATCATCGTGCAGCGCCTGCGCCAGAGCTTCGCGCAGAGCCGCATCAGCGTGAGCGAA
GGCGAGGTGGATACCGCGCTGGCCCAACAGGCCGCCACCGGTAGCCAGTACCACCTGGCGCACATCCTGATCGGCTTGCC
GGAAGGCGCAAATGCCGAGCAGATCGCCACCGGCCAGAAGAAGGTCGATGGCGTCAAAGCCTTGATCGACAAGGGCGAGC
TGGATTTTTCGGCCGCTGCGGTGCGTTATTCCGATAGCCCCAATGCGCTGGAAGGTGGCGATCTGGGCTGGCGCAGCCTG
GATGAAATTCCCAATGCATTCGCGCAGCTGATCCGCGACATGCAGCCTGGCCAGGTGGCCGGACCGCTGCGCGGCCCGAG
CGGCTTCCAGCTGCTCAAGCTGGTGGAAATGCGCGACGCCAATGCCGGCGGCGAAAAGAAGATGGTCACCGAGTACCACG
CACGCCACATCCTGGTGCGGATCGGCGACAACCAGACCGAGGCGCAGGCCAAGGCCAAGATCGATACGATTCGCGCACGC
ATCGTCGGTGGCGCCGATTTCCAGGCGACGGCCAAGGAGTCCTCAGAGGACACCAACAGCCGCGGCCAGGGTGGCGATCT
GGGCTGGTTCCCAGCCGACGCGTTCGGCCCGGACTTCGGCAAGCAGGTCGAAAGCTTGACCGACGGCGCGGTCTCCGAGC
CCTTCCGTACCCAGGCGGGCTGGCACATCGTGCAGCGCGTCGGCAGCCGCCAGACCGACGTCAGCGCCGAGAATCAGCGC
GCGCAGGTGCGCGAAACCATCGGTCGCCGCAAGCTGGAAGAAGAGTACAACCGCTATCTGCAGGAACTGCGTGGCGAAGC
GTATGTGAGCTACCGCACCGGCGACCGCGCCGATGACAACGCCACTGCCGCTCCAGCCAAATCGCCAGACCCTGCAGCGC
CCTCGCCGCCGCCGGCAAAGCCGACGCGCTGA

Upstream 100 bases:

>100_bases
TGCGCCGTGCTATTCTCGGCTATTACCGCGACGACCTCTACCTGGTCCCGCCCAGCAACACCACGACCAATCCGGACGAT
TACGATCCGAACCTGATTCC

Downstream 100 bases:

>100_bases
GGGCGGGCGCCCGGATCGCATGATGGTCCCGTCGCTCGCGCTGGTGCCAGGCGAGCCGGCCGGAATCGGGCCGGAACTCT
GCGTCCGGCTTGCCCAGCAG

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MTKPFSVVLASLLAITSTVSPLASAQQSQPLDRIAAIVDEDVVLQSELDRAVRNVKSQYAGRENQLPPDDVLQRQVLERL
VLVKLQVSRADGNGIRVSDEELNRAIASIAQQNGTTVDGLRQKLAADGMGYADFRASVRDEIIVQRLRQSFAQSRISVSE
GEVDTALAQQAATGSQYHLAHILIGLPEGANAEQIATGQKKVDGVKALIDKGELDFSAAAVRYSDSPNALEGGDLGWRSL
DEIPNAFAQLIRDMQPGQVAGPLRGPSGFQLLKLVEMRDANAGGEKKMVTEYHARHILVRIGDNQTEAQAKAKIDTIRAR
IVGGADFQATAKESSEDTNSRGQGGDLGWFPADAFGPDFGKQVESLTDGAVSEPFRTQAGWHIVQRVGSRQTDVSAENQR
AQVRETIGRRKLEEEYNRYLQELRGEAYVSYRTGDRADDNATAAPAKSPDPAAPSPPPAKPTR

Sequences:

>Translated_463_residues
MTKPFSVVLASLLAITSTVSPLASAQQSQPLDRIAAIVDEDVVLQSELDRAVRNVKSQYAGRENQLPPDDVLQRQVLERL
VLVKLQVSRADGNGIRVSDEELNRAIASIAQQNGTTVDGLRQKLAADGMGYADFRASVRDEIIVQRLRQSFAQSRISVSE
GEVDTALAQQAATGSQYHLAHILIGLPEGANAEQIATGQKKVDGVKALIDKGELDFSAAAVRYSDSPNALEGGDLGWRSL
DEIPNAFAQLIRDMQPGQVAGPLRGPSGFQLLKLVEMRDANAGGEKKMVTEYHARHILVRIGDNQTEAQAKAKIDTIRAR
IVGGADFQATAKESSEDTNSRGQGGDLGWFPADAFGPDFGKQVESLTDGAVSEPFRTQAGWHIVQRVGSRQTDVSAENQR
AQVRETIGRRKLEEEYNRYLQELRGEAYVSYRTGDRADDNATAAPAKSPDPAAPSPPPAKPTR
>Mature_462_residues
TKPFSVVLASLLAITSTVSPLASAQQSQPLDRIAAIVDEDVVLQSELDRAVRNVKSQYAGRENQLPPDDVLQRQVLERLV
LVKLQVSRADGNGIRVSDEELNRAIASIAQQNGTTVDGLRQKLAADGMGYADFRASVRDEIIVQRLRQSFAQSRISVSEG
EVDTALAQQAATGSQYHLAHILIGLPEGANAEQIATGQKKVDGVKALIDKGELDFSAAAVRYSDSPNALEGGDLGWRSLD
EIPNAFAQLIRDMQPGQVAGPLRGPSGFQLLKLVEMRDANAGGEKKMVTEYHARHILVRIGDNQTEAQAKAKIDTIRARI
VGGADFQATAKESSEDTNSRGQGGDLGWFPADAFGPDFGKQVESLTDGAVSEPFRTQAGWHIVQRVGSRQTDVSAENQRA
QVRETIGRRKLEEEYNRYLQELRGEAYVSYRTGDRADDNATAAPAKSPDPAAPSPPPAKPTR

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains

Homologues:

Organism=Escherichia coli, GI1786238, Length=428, Percent_Identity=35.7476635514019, Blast_Score=253, Evalue=2e-68,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): SURA_XANAC (Q8PP23)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_641217.1
- HSSP:   P24327
- ProteinModelPortal:   Q8PP23
- SMR:   Q8PP23
- GeneID:   1154936
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC0865
- NMPDR:   fig|190486.1.peg.861
- HOGENOM:   HBG391483
- OMA:   RHILIKT
- ProtClustDB:   CLSK446097
- BioCyc:   XAXO190486:XAC0865-MONOMER
- BRENDA:   5.2.1.8
- HAMAP:   MF_01183
- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N; SSF109998 Trigger_fac_C_bac

EC number: =5.2.1.8

Molecular weight: Translated: 50114; Mature: 49983

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS01096 PPIC_PPIASE_1; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPFSVVLASLLAITSTVSPLASAQQSQPLDRIAAIVDEDVVLQSELDRAVRNVKSQYA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GRENQLPPDDVLQRQVLERLVLVKLQVSRADGNGIRVSDEELNRAIASIAQQNGTTVDGL
CCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCEECHHHHHHHHHHHHHHCCCCHHHH
RQKLAADGMGYADFRASVRDEIIVQRLRQSFAQSRISVSEGEVDTALAQQAATGSQYHLA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEE
HILIGLPEGANAEQIATGQKKVDGVKALIDKGELDFSAAAVRYSDSPNALEGGDLGWRSL
EHEEECCCCCCHHHHHCCHHHHHHHHHHHHCCCCCHHHHEEEECCCCCCCCCCCCCHHHH
DEIPNAFAQLIRDMQPGQVAGPLRGPSGFQLLKLVEMRDANAGGEKKMVTEYHARHILVR
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCEEEEE
IGDNQTEAQAKAKIDTIRARIVGGADFQATAKESSEDTNSRGQGGDLGWFPADAFGPDFG
ECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHH
KQVESLTDGAVSEPFRTQAGWHIVQRVGSRQTDVSAENQRAQVRETIGRRKLEEEYNRYL
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QELRGEAYVSYRTGDRADDNATAAPAKSPDPAAPSPPPAKPTR
HHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TKPFSVVLASLLAITSTVSPLASAQQSQPLDRIAAIVDEDVVLQSELDRAVRNVKSQYA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GRENQLPPDDVLQRQVLERLVLVKLQVSRADGNGIRVSDEELNRAIASIAQQNGTTVDGL
CCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCEECHHHHHHHHHHHHHHCCCCHHHH
RQKLAADGMGYADFRASVRDEIIVQRLRQSFAQSRISVSEGEVDTALAQQAATGSQYHLA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEE
HILIGLPEGANAEQIATGQKKVDGVKALIDKGELDFSAAAVRYSDSPNALEGGDLGWRSL
EHEEECCCCCCHHHHHCCHHHHHHHHHHHHCCCCCHHHHEEEECCCCCCCCCCCCCHHHH
DEIPNAFAQLIRDMQPGQVAGPLRGPSGFQLLKLVEMRDANAGGEKKMVTEYHARHILVR
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCEEEEE
IGDNQTEAQAKAKIDTIRARIVGGADFQATAKESSEDTNSRGQGGDLGWFPADAFGPDFG
ECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHH
KQVESLTDGAVSEPFRTQAGWHIVQRVGSRQTDVSAENQRAQVRETIGRRKLEEEYNRYL
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QELRGEAYVSYRTGDRADDNATAAPAKSPDPAAPSPPPAKPTR
HHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12024217