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The map label for this gene is acoR [H]

Identifier: 21241425

GI number: 21241425

Start: 773462

End: 775447

Strand: Reverse

Name: acoR [H]

Synonym: XAC0654

Alternate gene names: 21241425

Gene position: 775447-773462 (Counterclockwise)

Preceding gene: 77748545

Following gene: 21241413

Centisome position: 14.98

GC content: 68.88

Gene sequence:

>1986_bases
GTGTCGGAAGTGACTGTCGCCAACCTCCTGCAGGCCACGCCTGGGCCCTCGTCCGCTGCCGAGGCCGAATCCGCGTTGCT
GGCACGGATGCGCCGCTTCCGCCAGATCGAACCACTGCCGCCAGCGCTGGCGCGCTCGTGGCAGCGCTGCCTGGACGAGT
ATGGGCTGAGTCCGGATGCGTCCCCGTCGCCGATGGTCCACGACGGCAGCGGGCTGCGCGAGCGCCAGCAGCGTCTCGAG
GAAGTGCTGCGCATCGCCAAGGTGGAGATGGAGAACCTCTACGAACAGATCGCCGGCGGCGGCTACGCCGTGGTGTTCGC
CGACGCCGAGGCGACCTTGCTGCACAGCGTGCACGACCCGGCATTGCTGCGCGAATTCCGCCAGACCGGGTTGTTCTGCG
GCGCCAGCTGGGCCGAGCGCTACCAGGGCACCAACGGTATCGGCACCTGCGCGGTGGAGCGCAGCGCGCTCGGCGTGCAC
CGCGGCGAGCATTACCTGGCCCGGCACCTGCCGCTGTCGTGCAGCGGTGCGCCCATCCTCGACCCGCACGGGCAATTGCT
GGCGGTGCTGGATGCGTCCACACCGGATGCGCGCGACACCAGGCTGGTACAACGCCATACCAGCGCGCTGGTGCGCATGT
CGGCGGCACAGATCGCACGTTCGTATTTCCTGGCGCAGTACCGGCACGCGTGGATCCTGCGCTTCCACAGCCGCCCGGAG
TTCGCCGGCCTGTTGCACGAGGCGCTGATGGCGATCGGCGCCGACGGCTGCGTGCTGGCCGTCAACGAAGCGGCACTGGA
ACAGCTCGGCAAGGGCGACCGCAGCCTGCTGGTCGGGCGCGACATCTCGCAGGTGATGCAGCTGGACTTCGACACCGTGG
AGCAGCGTGCGCGCAACGACGCCAGCACGCTGTGGTCGATCCGCTGCGCCTGCCACGGTCGCCGCTTCTTCGCCCTGGCG
CAGCCGCCGCGCCGCAACGTGGTTGCTGGCGGCGCGCAGGCCACCACCGCCGACGATGACCAGGCGGCTTACGCACGCGA
ACACGTCGGCTCCGATCCGCGCATGCGCCACAACCTGGACAACGCGCTGAAGCTGGTCGCGCATCGCGTGTCGATCCTGC
TATGTGGCGCCACCGGCACCGGCAAGGAGGAGTTCGCCAAGGCGGTGCACCGCGGCTCGCCATGGGCGGCGCGGCCGTTC
GTGGCGGTGAACTGTGCGGCGATCCCCGAGGCGCTGATCGAGAGCGAACTGTTCGGCTACGCACGCGGCGCGTTCACCGA
TGCCGCGCGCGAAGGCCGCCACGGCAAGTTGCTGCAGGCCAGCGGAGGCACCTTATTCCTGGACGAGATCGGCGACATGC
CGCTGCCGCTGCAGACGCGGCTGCTGCGCGTGCTCGAAGAACAGAGCGTGACCCCGCTGGGCAGCGACCGTGCGATGCCG
CTGGAACTGCACGTGATCAGCGCCAGCCACCGCGACCTGGCGCAGATGGTGGCCGCCGGCGAATTCCGCGAGGACCTGTA
CTACCGCCTCAACGGCGTGGTGCTGCACCTGCCGCCGCTACGCGAACGCAGCGACAAGGCCGAGCTGATTCGCACGCTGC
TGCGCGAAGAAAACGGCGAGCAAGGCGTGCGCATCAGCGAAGAGGCGCTGCACAAGCTGCTCAGCTACGCCTGGCCGGGT
AACTTGCGCCAACTGCGCAACGTGCTGCGCACGGCGGCCGTGCTGTGCAGTGACGAGGTGATTCGCTTGCCGAATCTGCC
GCAGGAGATCGTCGACGCCGGCAGCGCACCCTGCCTGGTCGATGGACGAGCGGTCGCGGCCGACGATATGTCTGGCCGCG
TGGCATTGGATCAGGCCGAGCGGCTGGTGCTGCAGCAACAACTCGAACGCCACCGCTGGAATGTCAGCCGCACCGCCGAT
GCCCTGGGCATCAGTCGCAACACGCTGTACCGCAAGCTGCGCAAGCATGGACTGGAGACGGGATGA

Upstream 100 bases:

>100_bases
AATCTCCAATCCCGGCGTTTGCTGCACCGCGGTTTGAGCCTCGCCCCGGTTTATGCGTCACTGCCGCTCTGGCCCCGGGT
AGGGACCGAGGAAGCGCCAC

Downstream 100 bases:

>100_bases
ATGGGGAATCGGGAATCGGGAATCGGGAATCGGGAATGGAGAAAAGCAGTTCGCTGACGCTCTACGATTCCCCATTCCCG
ATTCCCCATTCCCGTAGTCA

Product: transcriptional regulator AcoR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 660

Protein sequence:

>661_residues
MSEVTVANLLQATPGPSSAAEAESALLARMRRFRQIEPLPPALARSWQRCLDEYGLSPDASPSPMVHDGSGLRERQQRLE
EVLRIAKVEMENLYEQIAGGGYAVVFADAEATLLHSVHDPALLREFRQTGLFCGASWAERYQGTNGIGTCAVERSALGVH
RGEHYLARHLPLSCSGAPILDPHGQLLAVLDASTPDARDTRLVQRHTSALVRMSAAQIARSYFLAQYRHAWILRFHSRPE
FAGLLHEALMAIGADGCVLAVNEAALEQLGKGDRSLLVGRDISQVMQLDFDTVEQRARNDASTLWSIRCACHGRRFFALA
QPPRRNVVAGGAQATTADDDQAAYAREHVGSDPRMRHNLDNALKLVAHRVSILLCGATGTGKEEFAKAVHRGSPWAARPF
VAVNCAAIPEALIESELFGYARGAFTDAAREGRHGKLLQASGGTLFLDEIGDMPLPLQTRLLRVLEEQSVTPLGSDRAMP
LELHVISASHRDLAQMVAAGEFREDLYYRLNGVVLHLPPLRERSDKAELIRTLLREENGEQGVRISEEALHKLLSYAWPG
NLRQLRNVLRTAAVLCSDEVIRLPNLPQEIVDAGSAPCLVDGRAVAADDMSGRVALDQAERLVLQQQLERHRWNVSRTAD
ALGISRNTLYRKLRKHGLETG

Sequences:

>Translated_661_residues
MSEVTVANLLQATPGPSSAAEAESALLARMRRFRQIEPLPPALARSWQRCLDEYGLSPDASPSPMVHDGSGLRERQQRLE
EVLRIAKVEMENLYEQIAGGGYAVVFADAEATLLHSVHDPALLREFRQTGLFCGASWAERYQGTNGIGTCAVERSALGVH
RGEHYLARHLPLSCSGAPILDPHGQLLAVLDASTPDARDTRLVQRHTSALVRMSAAQIARSYFLAQYRHAWILRFHSRPE
FAGLLHEALMAIGADGCVLAVNEAALEQLGKGDRSLLVGRDISQVMQLDFDTVEQRARNDASTLWSIRCACHGRRFFALA
QPPRRNVVAGGAQATTADDDQAAYAREHVGSDPRMRHNLDNALKLVAHRVSILLCGATGTGKEEFAKAVHRGSPWAARPF
VAVNCAAIPEALIESELFGYARGAFTDAAREGRHGKLLQASGGTLFLDEIGDMPLPLQTRLLRVLEEQSVTPLGSDRAMP
LELHVISASHRDLAQMVAAGEFREDLYYRLNGVVLHLPPLRERSDKAELIRTLLREENGEQGVRISEEALHKLLSYAWPG
NLRQLRNVLRTAAVLCSDEVIRLPNLPQEIVDAGSAPCLVDGRAVAADDMSGRVALDQAERLVLQQQLERHRWNVSRTAD
ALGISRNTLYRKLRKHGLETG
>Mature_660_residues
SEVTVANLLQATPGPSSAAEAESALLARMRRFRQIEPLPPALARSWQRCLDEYGLSPDASPSPMVHDGSGLRERQQRLEE
VLRIAKVEMENLYEQIAGGGYAVVFADAEATLLHSVHDPALLREFRQTGLFCGASWAERYQGTNGIGTCAVERSALGVHR
GEHYLARHLPLSCSGAPILDPHGQLLAVLDASTPDARDTRLVQRHTSALVRMSAAQIARSYFLAQYRHAWILRFHSRPEF
AGLLHEALMAIGADGCVLAVNEAALEQLGKGDRSLLVGRDISQVMQLDFDTVEQRARNDASTLWSIRCACHGRRFFALAQ
PPRRNVVAGGAQATTADDDQAAYAREHVGSDPRMRHNLDNALKLVAHRVSILLCGATGTGKEEFAKAVHRGSPWAARPFV
AVNCAAIPEALIESELFGYARGAFTDAAREGRHGKLLQASGGTLFLDEIGDMPLPLQTRLLRVLEEQSVTPLGSDRAMPL
ELHVISASHRDLAQMVAAGEFREDLYYRLNGVVLHLPPLRERSDKAELIRTLLREENGEQGVRISEEALHKLLSYAWPGN
LRQLRNVLRTAAVLCSDEVIRLPNLPQEIVDAGSAPCLVDGRAVAADDMSGRVALDQAERLVLQQQLERHRWNVSRTADA
LGISRNTLYRKLRKHGLETG

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788905, Length=316, Percent_Identity=44.3037974683544, Blast_Score=241, Evalue=1e-64,
Organism=Escherichia coli, GI1789233, Length=297, Percent_Identity=42.0875420875421, Blast_Score=229, Evalue=5e-61,
Organism=Escherichia coli, GI1788550, Length=317, Percent_Identity=38.4858044164038, Blast_Score=220, Evalue=3e-58,
Organism=Escherichia coli, GI1790299, Length=330, Percent_Identity=40.6060606060606, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1786524, Length=330, Percent_Identity=40.9090909090909, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1790437, Length=311, Percent_Identity=38.9067524115756, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI87082117, Length=217, Percent_Identity=48.3870967741936, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1787583, Length=343, Percent_Identity=36.734693877551, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1789087, Length=296, Percent_Identity=38.8513513513513, Blast_Score=186, Evalue=5e-48,
Organism=Escherichia coli, GI87082152, Length=335, Percent_Identity=36.1194029850746, Blast_Score=182, Evalue=8e-47,
Organism=Escherichia coli, GI87081858, Length=647, Percent_Identity=25.0386398763524, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI87081872, Length=299, Percent_Identity=35.1170568561873, Blast_Score=156, Evalue=5e-39,
Organism=Escherichia coli, GI1789828, Length=256, Percent_Identity=36.71875, Blast_Score=136, Evalue=5e-33,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 72664; Mature: 72532

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEVTVANLLQATPGPSSAAEAESALLARMRRFRQIEPLPPALARSWQRCLDEYGLSPDA
CCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCC
SPSPMVHDGSGLRERQQRLEEVLRIAKVEMENLYEQIAGGGYAVVFADAEATLLHSVHDP
CCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHCCCH
ALLREFRQTGLFCGASWAERYQGTNGIGTCAVERSALGVHRGEHYLARHLPLSCSGAPIL
HHHHHHHHCCCCCCCHHHHHHCCCCCCEEHEEHHHHHHHHCCHHHHHHCCCCCCCCCCCC
DPHGQLLAVLDASTPDARDTRLVQRHTSALVRMSAAQIARSYFLAQYRHAWILRFHSRPE
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCH
FAGLLHEALMAIGADGCVLAVNEAALEQLGKGDRSLLVGRDISQVMQLDFDTVEQRARND
HHHHHHHHHHHHCCCCCEEEECHHHHHHHCCCCCEEEECCCHHHHHHCCHHHHHHHHCCC
ASTLWSIRCACHGRRFFALAQPPRRNVVAGGAQATTADDDQAAYAREHVGSDPRMRHNLD
HHHHHHHHHHHCCCEEEEECCCCCCCEEECCCCCCCCCCHHHHHHHHHCCCCCHHHHHHH
NALKLVAHRVSILLCGATGTGKEEFAKAVHRGSPWAARPFVAVNCAAIPEALIESELFGY
HHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
ARGAFTDAAREGRHGKLLQASGGTLFLDEIGDMPLPLQTRLLRVLEEQSVTPLGSDRAMP
HHHHHHHHHHCCCCCCEEECCCCEEEHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCE
LELHVISASHRDLAQMVAAGEFREDLYYRLNGVVLHLPPLRERSDKAELIRTLLREENGE
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHCCCC
QGVRISEEALHKLLSYAWPGNLRQLRNVLRTAAVLCSDEVIRLPNLPQEIVDAGSAPCLV
CCCEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCHHHHCCCCCCEEE
DGRAVAADDMSGRVALDQAERLVLQQQLERHRWNVSRTADALGISRNTLYRKLRKHGLET
CCCEEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHCCCCC
G
C
>Mature Secondary Structure 
SEVTVANLLQATPGPSSAAEAESALLARMRRFRQIEPLPPALARSWQRCLDEYGLSPDA
CCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCC
SPSPMVHDGSGLRERQQRLEEVLRIAKVEMENLYEQIAGGGYAVVFADAEATLLHSVHDP
CCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHCCCH
ALLREFRQTGLFCGASWAERYQGTNGIGTCAVERSALGVHRGEHYLARHLPLSCSGAPIL
HHHHHHHHCCCCCCCHHHHHHCCCCCCEEHEEHHHHHHHHCCHHHHHHCCCCCCCCCCCC
DPHGQLLAVLDASTPDARDTRLVQRHTSALVRMSAAQIARSYFLAQYRHAWILRFHSRPE
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCH
FAGLLHEALMAIGADGCVLAVNEAALEQLGKGDRSLLVGRDISQVMQLDFDTVEQRARND
HHHHHHHHHHHHCCCCCEEEECHHHHHHHCCCCCEEEECCCHHHHHHCCHHHHHHHHCCC
ASTLWSIRCACHGRRFFALAQPPRRNVVAGGAQATTADDDQAAYAREHVGSDPRMRHNLD
HHHHHHHHHHHCCCEEEEECCCCCCCEEECCCCCCCCCCHHHHHHHHHCCCCCHHHHHHH
NALKLVAHRVSILLCGATGTGKEEFAKAVHRGSPWAARPFVAVNCAAIPEALIESELFGY
HHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
ARGAFTDAAREGRHGKLLQASGGTLFLDEIGDMPLPLQTRLLRVLEEQSVTPLGSDRAMP
HHHHHHHHHHCCCCCCEEECCCCEEEHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCE
LELHVISASHRDLAQMVAAGEFREDLYYRLNGVVLHLPPLRERSDKAELIRTLLREENGE
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHCCCC
QGVRISEEALHKLLSYAWPGNLRQLRNVLRTAAVLCSDEVIRLPNLPQEIVDAGSAPCLV
CCCEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCHHHHCCCCCCEEE
DGRAVAADDMSGRVALDQAERLVLQQQLERHRWNVSRTADALGISRNTLYRKLRKHGLET
CCCEEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]