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The map label for this gene is mxaF [H]

Identifier: 21241419

GI number: 21241419

Start: 764330

End: 766315

Strand: Direct

Name: mxaF [H]

Synonym: XAC0648

Alternate gene names: 21241419

Gene position: 764330-766315 (Clockwise)

Preceding gene: 21241418

Following gene: 21241420

Centisome position: 14.77

GC content: 64.2

Gene sequence:

>1986_bases
ATGCTTGCGCTGAGCGCCGTTCTGTCTGGCTGCAAGAAAGACACACCCACCGAAACTGCGGCGCCGGCAACGGCTGCAAC
ACCTGCCGCTGCGCCCGCCGCTGCACCCGCCGCCGCGGCCGTGGTCGACACCGATAGCGAGTTCACCGCCAATGCCAGCA
ATGCGGACAACTGGGGTGGCGTGGGGCGCGACTTCGCACTCACCCGGCATAGCCCGCTGGCCGAGATCAATCGCGACAAC
GTCAAGAATCTGAAGATGTCGTGGGAGATGAAAACCGACGCCACGCGCGGCCACGAAGGCCAGCCGCTGGTGATCGGCAG
CATCATGTACATGGTCAGCGCGTATCCGAACAACGTGTTCGCCATCGATCTTGCGGCGCAGGACGACGGCGGCAAGGTGT
TGTGGAAATACACCCCGCAACAGGACGAACGGTCGGTGGCGGTGGCGTGCTGCGACACGGTCAATCGCGGCGCCTCGTAT
GCCGACGGCAAGCTGGTCTTCGGCAGCCTCAGCGGCGATGTGATCGCGCTCGATGCCAAGACCGGCAAGGAAGTGTGGAA
GCAAAAACTTGCGCACCCGGACAAGGGCGAAACCATCACCATGGCGCCGATCATCGCCGACGGCAAGGTGGTTGCCGGCA
TCAGCGGCAACGAGTTCGGCGTGCTCGGTCGCGTGGCCGCCTACAACCTTGACGATGGCAAGCAGGCATGGTCCTGCGAT
GCGGCCGGTACCGACAAGGCGATCTGCCTGGGCCCGGATTTCAACAAGGCCAATCCGCAGCATGGCCAGCTCGGCGACCT
GGGCGTCAAGACCTTTCCCAACGACGAATGGAAGCGCGGAGGCGGTGCAGCCTGGGGCTGGTACAGCTACGACCCGAAGT
TGAAGCTGGTGTACTACGGCACCGGCAATCCCGGCCTGTGGAGCCCGTCGTACCGTTGCGGCAAGACCTCGCAGGAGGAA
TGCAACAACGGCGAGCATGACAACAAGTGGTCGATGACCTTGTTCGCGCGCAAGATCGATACCGGCGAGGCGGTGTGGGG
CTACCAGAAGACCCCGTTCGACCAGTGGGATTACGACGGCATCAACGAGCCGATCCTGGTCGACCTGAGCATCGATGGCA
AGCAGGTTCCGTCGGTGGTGCAGTTCGACCGCAACGGGTTTGCCTACGTGCTCGATCGGCGCGATGGCACGCTGCTGCGC
GCGCACAAGTTCGTGCCGGCCAACTGGGCCGAACGCATCGACATGAAGACCGGTCGCCCGGTGAAGGTGGCCGCGCATTC
GCCGCTGGAACGCGGCAAGAAGGTGCAGGCGTTCCCGTCGGCGATGGGCGGCAAGGACCAGCAGCCGTGCTCGGTGGATC
CGGCCAATGCGGCGGTGTTCTTCTGCGGCACCAATAACTGGCACATGGAGCTGGAACCGCAGGAGCGCGGCAACACCATG
ATGGGTCTGCCGTACGTGTTCGCCAACGTGATGATGAAGCCGAATGAGCCGGGCGCGCTGGGCATCGTCAAGGCGTTCGA
TGTGGTGGAAGGCAAGTCCAAGTGGGAGATCAAGGAGAAGTATCCGGTGTGGAGCGGCACCCTGGTCACCGACGGCGGGC
TGGTGTTCTACGGCACGCTGGATGGGTGGTTCCGCGCGGTGGACAAGGACACCGGCAAGAAGTTGTGGGAGACCAAGTTG
CCGTCCGGCATCATCGGTAACCCCATCGCCTACAAGGCCAACGGCCATCAGTACGTGGCGGTGTTCTCCGGTATCGGCGG
GTGGATCGGCTTGCCGGTCACTGCAGGCCTGGATCCGTCCGATCCGTATGGCGCACTGGGTGCGGCGGGGCTGGCGTTCG
GTGCGGGCTTCGACAAGATCCCGCTCGGCGGCATGGTCCACAGCTTCCGTATCGATGGCGCCGGCAAGACCGTGACTGCC
ACTGCCACTGCCACTGCCACCGCAGGCGGCGGCACCGCCAATGCAGCAGCGAAGACGGCACGATGA

Upstream 100 bases:

>100_bases
TGCGCTGCGGGATGTTTCAACCGACTGGTTGTTCAAACGAGAGGGGTAGACGCACATGCACCAATCTTCCTGTCGCAGCG
TACGCAGCGCCGCGCTGCTC

Downstream 100 bases:

>100_bases
CCTGCACGCAAGGCGTTGGGCGCGCACCTCGGCAGCTTGCTGCCGGGGTGCGCGGCATCACCCGGCACCTGCAGCAGGTG
CTGGTGCTGTGCAGCCTCGG

Product: methanol dehydrogenase heavy chain

Products: D-gluconolactone; reduced acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MLALSAVLSGCKKDTPTETAAPATAATPAAAPAAAPAAAAVVDTDSEFTANASNADNWGGVGRDFALTRHSPLAEINRDN
VKNLKMSWEMKTDATRGHEGQPLVIGSIMYMVSAYPNNVFAIDLAAQDDGGKVLWKYTPQQDERSVAVACCDTVNRGASY
ADGKLVFGSLSGDVIALDAKTGKEVWKQKLAHPDKGETITMAPIIADGKVVAGISGNEFGVLGRVAAYNLDDGKQAWSCD
AAGTDKAICLGPDFNKANPQHGQLGDLGVKTFPNDEWKRGGGAAWGWYSYDPKLKLVYYGTGNPGLWSPSYRCGKTSQEE
CNNGEHDNKWSMTLFARKIDTGEAVWGYQKTPFDQWDYDGINEPILVDLSIDGKQVPSVVQFDRNGFAYVLDRRDGTLLR
AHKFVPANWAERIDMKTGRPVKVAAHSPLERGKKVQAFPSAMGGKDQQPCSVDPANAAVFFCGTNNWHMELEPQERGNTM
MGLPYVFANVMMKPNEPGALGIVKAFDVVEGKSKWEIKEKYPVWSGTLVTDGGLVFYGTLDGWFRAVDKDTGKKLWETKL
PSGIIGNPIAYKANGHQYVAVFSGIGGWIGLPVTAGLDPSDPYGALGAAGLAFGAGFDKIPLGGMVHSFRIDGAGKTVTA
TATATATAGGGTANAAAKTAR

Sequences:

>Translated_661_residues
MLALSAVLSGCKKDTPTETAAPATAATPAAAPAAAPAAAAVVDTDSEFTANASNADNWGGVGRDFALTRHSPLAEINRDN
VKNLKMSWEMKTDATRGHEGQPLVIGSIMYMVSAYPNNVFAIDLAAQDDGGKVLWKYTPQQDERSVAVACCDTVNRGASY
ADGKLVFGSLSGDVIALDAKTGKEVWKQKLAHPDKGETITMAPIIADGKVVAGISGNEFGVLGRVAAYNLDDGKQAWSCD
AAGTDKAICLGPDFNKANPQHGQLGDLGVKTFPNDEWKRGGGAAWGWYSYDPKLKLVYYGTGNPGLWSPSYRCGKTSQEE
CNNGEHDNKWSMTLFARKIDTGEAVWGYQKTPFDQWDYDGINEPILVDLSIDGKQVPSVVQFDRNGFAYVLDRRDGTLLR
AHKFVPANWAERIDMKTGRPVKVAAHSPLERGKKVQAFPSAMGGKDQQPCSVDPANAAVFFCGTNNWHMELEPQERGNTM
MGLPYVFANVMMKPNEPGALGIVKAFDVVEGKSKWEIKEKYPVWSGTLVTDGGLVFYGTLDGWFRAVDKDTGKKLWETKL
PSGIIGNPIAYKANGHQYVAVFSGIGGWIGLPVTAGLDPSDPYGALGAAGLAFGAGFDKIPLGGMVHSFRIDGAGKTVTA
TATATATAGGGTANAAAKTAR
>Mature_661_residues
MLALSAVLSGCKKDTPTETAAPATAATPAAAPAAAPAAAAVVDTDSEFTANASNADNWGGVGRDFALTRHSPLAEINRDN
VKNLKMSWEMKTDATRGHEGQPLVIGSIMYMVSAYPNNVFAIDLAAQDDGGKVLWKYTPQQDERSVAVACCDTVNRGASY
ADGKLVFGSLSGDVIALDAKTGKEVWKQKLAHPDKGETITMAPIIADGKVVAGISGNEFGVLGRVAAYNLDDGKQAWSCD
AAGTDKAICLGPDFNKANPQHGQLGDLGVKTFPNDEWKRGGGAAWGWYSYDPKLKLVYYGTGNPGLWSPSYRCGKTSQEE
CNNGEHDNKWSMTLFARKIDTGEAVWGYQKTPFDQWDYDGINEPILVDLSIDGKQVPSVVQFDRNGFAYVLDRRDGTLLR
AHKFVPANWAERIDMKTGRPVKVAAHSPLERGKKVQAFPSAMGGKDQQPCSVDPANAAVFFCGTNNWHMELEPQERGNTM
MGLPYVFANVMMKPNEPGALGIVKAFDVVEGKSKWEIKEKYPVWSGTLVTDGGLVFYGTLDGWFRAVDKDTGKKLWETKL
PSGIIGNPIAYKANGHQYVAVFSGIGGWIGLPVTAGLDPSDPYGALGAAGLAFGAGFDKIPLGGMVHSFRIDGAGKTVTA
TATATATAGGGTANAAAKTAR

Specific function: Gdh Is Probably Involved In Energy Conservation Rather Than In Sugar Metabolism. [C]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=663, Percent_Identity=24.8868778280543, Blast_Score=139, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: 1.1.5.2 [C]

Molecular weight: Translated: 70409; Mature: 70409

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLALSAVLSGCKKDTPTETAAPATAATPAAAPAAAPAAAAVVDTDSEFTANASNADNWGG
CEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEECCCCCCCCCC
VGRDFALTRHSPLAEINRDNVKNLKMSWEMKTDATRGHEGQPLVIGSIMYMVSAYPNNVF
CCCCEEEECCCCHHHCCCCCCCEEEEEEEEECCCCCCCCCCCEEHHHHHHHHHCCCCCEE
AIDLAAQDDGGKVLWKYTPQQDERSVAVACCDTVNRGASYADGKLVFGSLSGDVIALDAK
EEEEEECCCCCEEEEEECCCCCCCCEEEEEEHHHCCCCCCCCCEEEEEECCCCEEEEECC
TGKEVWKQKLAHPDKGETITMAPIIADGKVVAGISGNEFGVLGRVAAYNLDDGKQAWSCD
CCHHHHHHHCCCCCCCCEEEEEEEEECCCEEEECCCCCCCEEEEEEEECCCCCCCEEECC
AAGTDKAICLGPDFNKANPQHGQLGDLGVKTFPNDEWKRGGGAAWGWYSYDPKLKLVYYG
CCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEECCEEEEEEEE
TGNPGLWSPSYRCGKTSQEECNNGEHDNKWSMTLFARKIDTGEAVWGYQKTPFDQWDYDG
CCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEEEEECCCCCEEECCCCCCCCCCCCCC
INEPILVDLSIDGKQVPSVVQFDRNGFAYVLDRRDGTLLRAHKFVPANWAERIDMKTGRP
CCCCEEEEEECCCCCCCCEEEECCCCEEEEEECCCCCEEEEEECCCCCHHHHHCCCCCCC
VKVAAHSPLERGKKVQAFPSAMGGKDQQPCSVDPANAAVFFCGTNNWHMELEPQERGNTM
EEEEECCCHHHCCEEEECHHHCCCCCCCCCCCCCCCEEEEEEECCCEEEEECHHHHCCEE
MGLPYVFANVMMKPNEPGALGIVKAFDVVEGKSKWEIKEKYPVWSGTLVTDGGLVFYGTL
EECHHHHHHHEECCCCCCCEEEEEEEHHHCCCCCEEEEECCCCCCCEEEECCCEEEEECC
DGWFRAVDKDTGKKLWETKLPSGIIGNPIAYKANGHQYVAVFSGIGGWIGLPVTAGLDPS
CHHHHHHCCHHCHHHHHHCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCCEECCCCCC
DPYGALGAAGLAFGAGFDKIPLGGMVHSFRIDGAGKTVTATATATATAGGGTANAAAKTA
CCCCCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEEEEEEEEEEECCCCCCCCHHCCC
R
C
>Mature Secondary Structure
MLALSAVLSGCKKDTPTETAAPATAATPAAAPAAAPAAAAVVDTDSEFTANASNADNWGG
CEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEECCCCCCCCCC
VGRDFALTRHSPLAEINRDNVKNLKMSWEMKTDATRGHEGQPLVIGSIMYMVSAYPNNVF
CCCCEEEECCCCHHHCCCCCCCEEEEEEEEECCCCCCCCCCCEEHHHHHHHHHCCCCCEE
AIDLAAQDDGGKVLWKYTPQQDERSVAVACCDTVNRGASYADGKLVFGSLSGDVIALDAK
EEEEEECCCCCEEEEEECCCCCCCCEEEEEEHHHCCCCCCCCCEEEEEECCCCEEEEECC
TGKEVWKQKLAHPDKGETITMAPIIADGKVVAGISGNEFGVLGRVAAYNLDDGKQAWSCD
CCHHHHHHHCCCCCCCCEEEEEEEEECCCEEEECCCCCCCEEEEEEEECCCCCCCEEECC
AAGTDKAICLGPDFNKANPQHGQLGDLGVKTFPNDEWKRGGGAAWGWYSYDPKLKLVYYG
CCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEECCEEEEEEEE
TGNPGLWSPSYRCGKTSQEECNNGEHDNKWSMTLFARKIDTGEAVWGYQKTPFDQWDYDG
CCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEEEEECCCCCEEECCCCCCCCCCCCCC
INEPILVDLSIDGKQVPSVVQFDRNGFAYVLDRRDGTLLRAHKFVPANWAERIDMKTGRP
CCCCEEEEEECCCCCCCCEEEECCCCEEEEEECCCCCEEEEEECCCCCHHHHHCCCCCCC
VKVAAHSPLERGKKVQAFPSAMGGKDQQPCSVDPANAAVFFCGTNNWHMELEPQERGNTM
EEEEECCCHHHCCEEEECHHHCCCCCCCCCCCCCCCEEEEEEECCCEEEEECHHHHCCEE
MGLPYVFANVMMKPNEPGALGIVKAFDVVEGKSKWEIKEKYPVWSGTLVTDGGLVFYGTL
EECHHHHHHHEECCCCCCCEEEEEEEHHHCCCCCEEEEECCCCCCCEEEECCCEEEEECC
DGWFRAVDKDTGKKLWETKLPSGIIGNPIAYKANGHQYVAVFSGIGGWIGLPVTAGLDPS
CHHHHHHCCHHCHHHHHHCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCCEECCCCCC
DPYGALGAAGLAFGAGFDKIPLGGMVHSFRIDGAGKTVTATATATATAGGGTANAAAKTA
CCCCCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEEEEEEEEEEECCCCCCCCHHCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pqq. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-Glucose; acceptor [C]

Specific reaction: D-Glucose + acceptor = D-gluconolactone + reduced acceptor [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1657873 [H]