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The map label for this gene is 21241377

Identifier: 21241377

GI number: 21241377

Start: 711552

End: 712304

Strand: Direct

Name: 21241377

Synonym: XAC0606

Alternate gene names: NA

Gene position: 711552-712304 (Clockwise)

Preceding gene: 21241373

Following gene: 21241378

Centisome position: 13.75

GC content: 60.69

Gene sequence:

>753_bases
ATGCCAGAAGGTCCCTCACTTGTCATCCTGCGCGAAGACACCCAAGCGTTCGTCGGTCGCAAGATCGTGCGTGTGTCCGG
CAACAGCAAGCAGGACATCGCCCGTCTGGACCAGCAAAAAGTGCTGGCACTGCGCAGCTGGGGCAAACACTTTTTGATCG
AATTTGCGCACTTCAGCGTGCGCATCCATTTCCTGCTGTTCGGCAGCTACCGCATCAACGAAGACAAACCCAACGCGGTG
CCGCGCTTGTGCCTGGAATTTTCCAAAGGCCAGCGGCTGAATTTCTATGCGTGCTCGGTACAGTTCATCGAGCGTCCGCT
GGACGAGATCTACGACTGGACGGCGGACGTGATGAACCCACTGTGGGACGCCGCGCAGGCGCGCCGCAAATTACGCGCCG
CTCCGGCACTGCTGGCGGCCGATGCACTGCTCGACCAGACCATCTTTGCCGGCGTGGGCAACATCATCAAGAACGAGGTG
CTGCATCGTATCCGCGTGCATCCGGAAAGTACCGTGGGCGCGCTACCGGCGCGCAAGCTGGGCGAACTGGTCACCCAGGC
ACGCGACTACAGTTTCGACTTCTACACCTGGAAAAAGGCCTTCGTGCTGAAGAAGCATTATCAGGTGCACACCAAGACCC
GTTGCCCGCGCGACGGCGCACCGCTGCAATACCGCAAGCACTTGGGCAAGGCCGGGCGTCGCGCGTTTTTCTGCGAGGTA
TGCCAGCGCTTGTACCGCGCCGACGAGGCCTGA

Upstream 100 bases:

>100_bases
GGTAAGCTGGGGGCGGCAGCACTCTATGCATGCATGTGCGTCAGGATGCCGTGTGCATCGCGATCACGGGCGAATCACGC
AGCGCTTCGATACTGGGCGC

Downstream 100 bases:

>100_bases
GGTACGCCGCGCCGCGGCCCGGAAAGCGGCGATCGGATCGGGGAATGCATGCTGATGGATTGCGATCGCTCAGCAGCAGT
CCGTGCGGGCCGAGACCTGC

Product: endonuclease

Products: NA

Alternate protein names: DNA-Formamidopyrimidine Glycosylase; Formamidopyrimidine-DNA Glycolase

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MPEGPSLVILREDTQAFVGRKIVRVSGNSKQDIARLDQQKVLALRSWGKHFLIEFAHFSVRIHFLLFGSYRINEDKPNAV
PRLCLEFSKGQRLNFYACSVQFIERPLDEIYDWTADVMNPLWDAAQARRKLRAAPALLAADALLDQTIFAGVGNIIKNEV
LHRIRVHPESTVGALPARKLGELVTQARDYSFDFYTWKKAFVLKKHYQVHTKTRCPRDGAPLQYRKHLGKAGRRAFFCEV
CQRLYRADEA

Sequences:

>Translated_250_residues
MPEGPSLVILREDTQAFVGRKIVRVSGNSKQDIARLDQQKVLALRSWGKHFLIEFAHFSVRIHFLLFGSYRINEDKPNAV
PRLCLEFSKGQRLNFYACSVQFIERPLDEIYDWTADVMNPLWDAAQARRKLRAAPALLAADALLDQTIFAGVGNIIKNEV
LHRIRVHPESTVGALPARKLGELVTQARDYSFDFYTWKKAFVLKKHYQVHTKTRCPRDGAPLQYRKHLGKAGRRAFFCEV
CQRLYRADEA
>Mature_249_residues
PEGPSLVILREDTQAFVGRKIVRVSGNSKQDIARLDQQKVLALRSWGKHFLIEFAHFSVRIHFLLFGSYRINEDKPNAVP
RLCLEFSKGQRLNFYACSVQFIERPLDEIYDWTADVMNPLWDAAQARRKLRAAPALLAADALLDQTIFAGVGNIIKNEVL
HRIRVHPESTVGALPARKLGELVTQARDYSFDFYTWKKAFVLKKHYQVHTKTRCPRDGAPLQYRKHLGKAGRRAFFCEVC
QRLYRADEA

Specific function: Unknown

COG id: COG0266

COG function: function code L; Formamidopyrimidine-DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI157388969, Length=244, Percent_Identity=27.4590163934426, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI209364526, Length=168, Percent_Identity=32.7380952380952, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI21450800, Length=168, Percent_Identity=32.7380952380952, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI209364528, Length=168, Percent_Identity=32.7380952380952, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 28771; Mature: 28639

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: PS51068 FPG_CAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEGPSLVILREDTQAFVGRKIVRVSGNSKQDIARLDQQKVLALRSWGKHFLIEFAHFSV
CCCCCCEEEEECCHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHE
RIHFLLFGSYRINEDKPNAVPRLCLEFSKGQRLNFYACSVQFIERPLDEIYDWTADVMNP
EEEEEEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
LWDAAQARRKLRAAPALLAADALLDQTIFAGVGNIIKNEVLHRIRVHPESTVGALPARKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHH
GELVTQARDYSFDFYTWKKAFVLKKHYQVHTKTRCPRDGAPLQYRKHLGKAGRRAFFCEV
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHH
CQRLYRADEA
HHHHHCCCCC
>Mature Secondary Structure 
PEGPSLVILREDTQAFVGRKIVRVSGNSKQDIARLDQQKVLALRSWGKHFLIEFAHFSV
CCCCCEEEEECCHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHE
RIHFLLFGSYRINEDKPNAVPRLCLEFSKGQRLNFYACSVQFIERPLDEIYDWTADVMNP
EEEEEEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
LWDAAQARRKLRAAPALLAADALLDQTIFAGVGNIIKNEVLHRIRVHPESTVGALPARKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHH
GELVTQARDYSFDFYTWKKAFVLKKHYQVHTKTRCPRDGAPLQYRKHLGKAGRRAFFCEV
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHH
CQRLYRADEA
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA