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The map label for this gene is aroQ

Identifier: 21241304

GI number: 21241304

Start: 621845

End: 622291

Strand: Reverse

Name: aroQ

Synonym: XAC0533

Alternate gene names: 21241304

Gene position: 622291-621845 (Counterclockwise)

Preceding gene: 21241305

Following gene: 21241303

Centisome position: 12.02

GC content: 68.68

Gene sequence:

>447_bases
ATGGCCCATCTGCTGCTGTTGCATGGCCCCAACCTCAACCTGCTCGGCACCCGCGAGCCGGAGGTTTACGGGCGTACCAC
GCTGGCGCAGATCGATGCGGCCCTGGTGGACCGCGCGCAAGCGGCCGGGCACGTGCTGCACTGCCTGCAGTCCAATGCCG
AGCACGTGCTGGTGGAGCGCATCCACGCCGCGCGCGAGGACGGCACCGCCTACATCCTGATCAACCCGGCCGCCTTCACC
CATACCTCGGTGGCGCTGCGCGATGCGCTGCTGGGCGTGGGGCTGCCGTTCGTGGAAATTCATCTGTCCAACCCGCACGC
GCGCGAGCCGTTCCGGCACCACAGCTATCTCAGCGACAAGGCCGACGGGGTGATCTGCGGCTTTGGCGCCGACAGCTACC
GGCTGGCCCTGGAAGCGGTGATCGCGCGCCTGGAGCGCGACGCATGA

Upstream 100 bases:

>100_bases
GAAATTTAAAACAATCGTTTTAAACAGACCTAAGTTCGTCGAACTGGACAGCATCGACGACATCGCGCAGACTTCCGGCC
TTTCCGCTCTTGCCGATCCC

Downstream 100 bases:

>100_bases
CCCCTGCCGCATCGACCTCGGCCAGCGCGCCGGCGTCCTGATCCCATTCCGCCGGCATCCGCCGGCACTCCCCACCGTTT
CACTTCCAGAGGCCCTTATG

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MAHLLLLHGPNLNLLGTREPEVYGRTTLAQIDAALVDRAQAAGHVLHCLQSNAEHVLVERIHAAREDGTAYILINPAAFT
HTSVALRDALLGVGLPFVEIHLSNPHAREPFRHHSYLSDKADGVICGFGADSYRLALEAVIARLERDA

Sequences:

>Translated_148_residues
MAHLLLLHGPNLNLLGTREPEVYGRTTLAQIDAALVDRAQAAGHVLHCLQSNAEHVLVERIHAAREDGTAYILINPAAFT
HTSVALRDALLGVGLPFVEIHLSNPHAREPFRHHSYLSDKADGVICGFGADSYRLALEAVIARLERDA
>Mature_147_residues
AHLLLLHGPNLNLLGTREPEVYGRTTLAQIDAALVDRAQAAGHVLHCLQSNAEHVLVERIHAAREDGTAYILINPAAFTH
TSVALRDALLGVGLPFVEIHLSNPHAREPFRHHSYLSDKADGVICGFGADSYRLALEAVIARLERDA

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_XANAC (Q8PPZ9)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_640886.1
- ProteinModelPortal:   Q8PPZ9
- SMR:   Q8PPZ9
- GeneID:   1154604
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC0533
- HOGENOM:   HBG284657
- OMA:   TFQSNHE
- ProtClustDB:   PRK05395
- BioCyc:   XAXO190486:XAC0533-MONOMER
- BRENDA:   4.2.1.10
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 16109; Mature: 15977

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 23-23 ACT_SITE 101-101 BINDING 75-75 BINDING 81-81 BINDING 88-88 BINDING 112-112

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHLLLLHGPNLNLLGTREPEVYGRTTLAQIDAALVDRAQAAGHVLHCLQSNAEHVLVER
CCEEEEEECCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IHAAREDGTAYILINPAAFTHTSVALRDALLGVGLPFVEIHLSNPHAREPFRHHSYLSDK
HHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHCCCCCC
ADGVICGFGADSYRLALEAVIARLERDA
CCEEEEECCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AHLLLLHGPNLNLLGTREPEVYGRTTLAQIDAALVDRAQAAGHVLHCLQSNAEHVLVER
CEEEEEECCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IHAAREDGTAYILINPAAFTHTSVALRDALLGVGLPFVEIHLSNPHAREPFRHHSYLSDK
HHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHCCCCCC
ADGVICGFGADSYRLALEAVIARLERDA
CCEEEEECCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217