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The map label for this gene is dsbD [H]

Identifier: 21241305

GI number: 21241305

Start: 623135

End: 625435

Strand: Reverse

Name: dsbD [H]

Synonym: XAC0534

Alternate gene names: 21241305

Gene position: 625435-623135 (Counterclockwise)

Preceding gene: 21241306

Following gene: 21241304

Centisome position: 12.08

GC content: 70.1

Gene sequence:

>2301_bases
GTGAGGAACCGTAAGCCGATGACCGTGCTGCACCGTATCGCCGCCCTGTGCCTGCTGGCCCTGGCCGCTTTCCCCGCCCT
GGCGATCAGCGAAAAGGATCTGCTGCCAGTGGACCAGGCCTTCGCGCTGAGCGCCACCGCCGACAGCCGCGACCGCATCG
CGCTGAACTGGAAGATCGCACCGGGCTACTACCTGTATCGCCACCGCATCAGCGTCAAGGCCGGAAAGGGGTTTGCCGCG
GGCGAACTGGCGCTGCCGGAGGGCGAGAGCAAACACGACGAGTTCTTCGGCCAGGTGCAGACCTACCGCAAGCAACTGCA
GGCCACCCTGGCCGGCAAGGCCGACCCGGCGGTGCAGACCGCCGTCCTGCAGGTGCAGTACCAGGGCTGCGCCGATGCCG
GCGTGTGCTATCCGCCGCAGCGGCGCGAAATCCGCGTCGACCTGCCCGCGGCCGATGCCACCGGGGCACAGGCCACTGCT
GCGCCACGCGAAAATCTGGGCGCGCTGGTGCCACGCAGCGCCGCCGGCCCGCGCCTGTTCGGCGCCCCCGGCCAGACCGC
CGGCGTGGACGCGTTGCCGCTGCCGGCCGAGCAGGCGTTCAACTTCGAAGCCATCGTCGGCGACGGCAACAGCCTGCTGC
TGCGCTTCACCCCGGCGCCGGGCTACTACATCTACCGCGACCGCACCTCGCTGGCACTGGAAGGCGCCAGCGGCGTGCGC
ACCGGGCTGCCGCGCTGGCCGCAAGGCAAGGCCCACCGCGACGAGCACTTCGGCGATGTGGTGGTGTATTTCGACCAGGC
CGAAGTGACCTTGCCGCTGCTGCGCGACCACCCTGATCCGGCCCACGTGACCCTGGTGGCCACCTTCCAGGGCTGCCAGA
CCGACGGTATCTGCTATCCGCCGATGACCCGCCGCGTCGCCCTCGATGTGCCGGCCGGAATCGTGTCGCCGCAGAACCAG
GCCCAGGCTTCGCCGTTGATGATTTCGCCGCTGGCTGCCGGTCAGGCACCGGTCGAGCCCGCGCCTGCCGCCAGCACTGC
CGGTCCGGTCGCCGATGCCTCGGCCGGCAATCCGGAGCGCACGCCGCCGCCGCATACCGACAAGGGCCTGCTGGGCATGC
TGGTACTGGCGCTGCTTGGCGGGTTGGTGCTGAACCTGATGCCCTGCGTGCTGCCGATCCTGTCGCTGAAGGTGCTGGGC
CTGGCGCACAGCGGCGAGAGCCGCGGCCACGCACGTAGCCATGCGACCTGGTACTCGCTGGGCGTGCTGGTGTCCTTCGC
CGCCATTGGCGGGCTGGTGATCGGCTTGCGCGCCGCCGGGCAGGCCGCCGGCTGGGGCTTCCAGTTGCAGCAGCCGTGGT
TCGTCGCCGCGCTGGCCTATCTGATGTTCGCGGTGGGGCTGAGCCTGTCGGGCGTGTTCACCTTGGGCACCAACCTGGGC
GGCATCGGGCAGTCGCTGGCCGCCCGCAACGGACCACTGGGCGACTTCTTCACCGGCGTGCTGGCCTGCGTGGTCGCCAG
CCCCTGCATCGCGCCGTTCATGGGCACGGCACTGGCCTACGCCTTCACCGCGCCCGCGCTGCTGGCGATGCTGGTATTCC
TGGCGCTGGGCCTGGGCCTGGCGTTGCCGTTCCTGCTGATCGGCTTCGTGCCTTCGCTGGCGCGGCGCCTGCCCACCCCC
GGGGCGTGGATGGAAACGCTCAAGCAGGTGCTGGCGTTCCCGATGTATCTCACCGCGATCTGGCTGCTGTGGGTATTGGG
CAAGCAACGCGGCGTGGATGCGCTGGCCTTGATGTTGGTCGGCGCCACCCTGCTGGCCTTGGGCCTGTGGTGCTTCGAGC
GCAGCCGCTGGAAGAGCCACCGCCTGGGCATGGGCCTGGCCACGGCGATGCTGGTGCTGGCGCTGGTGCCGGTGGTCGCG
GTCACGCGCCTGAGCCTGCCGGCGGCCACCGCGACCGAGGGCGTGGTGGCGTTCTCCCCGCAGTTGCTGGACCGCCTGCG
CGCCGACAACCGCGTGGTCTTCGTCAACATGACCGCCGATTGGTGCGTGACCTGCAAGGCCAACGAAAAGAACGTACTGA
GCAGCGCCGAATTCCGCGACGCGTTGCGCCGCGTCGATGCGGTCTACATGAAGGGCGACTGGACCAATGTCGACCCCGCC
ATCAGCACCTTCCTCGACCAGCACCAGGCCGTCGGCGTGCCGCTGTACGTGGTCTACGGCCCCGGCGCCCCACCGGCGAT
CCTGCCGACCGTGCTGACCGGCGCCATTACCGAAGACGCCTTGCTGCGCGCAGCGCGGTGA

Upstream 100 bases:

>100_bases
CGGCTGTGCGAGCTGCACCCCTTCGACCTCCCCGAACTGATCGAGCTCGAGGTCGCCGGCGGCTTGCCTGCCTACCTGCA
GTGGGTGTACGCCGAAACCC

Downstream 100 bases:

>100_bases
GGCAGCGCCTTCGCTGCAGCTGGTGACCTCGGCGGCCGTCTGTTGGCGGGCTAGGTCGAAGATGTTGCGAATCATGTAGA
CCGGCACCCGCGCCACGAGG

Product: C-type cytochrome biogenesis protein (copper tolerance)

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 766; Mature: 766

Protein sequence:

>766_residues
MRNRKPMTVLHRIAALCLLALAAFPALAISEKDLLPVDQAFALSATADSRDRIALNWKIAPGYYLYRHRISVKAGKGFAA
GELALPEGESKHDEFFGQVQTYRKQLQATLAGKADPAVQTAVLQVQYQGCADAGVCYPPQRREIRVDLPAADATGAQATA
APRENLGALVPRSAAGPRLFGAPGQTAGVDALPLPAEQAFNFEAIVGDGNSLLLRFTPAPGYYIYRDRTSLALEGASGVR
TGLPRWPQGKAHRDEHFGDVVVYFDQAEVTLPLLRDHPDPAHVTLVATFQGCQTDGICYPPMTRRVALDVPAGIVSPQNQ
AQASPLMISPLAAGQAPVEPAPAASTAGPVADASAGNPERTPPPHTDKGLLGMLVLALLGGLVLNLMPCVLPILSLKVLG
LAHSGESRGHARSHATWYSLGVLVSFAAIGGLVIGLRAAGQAAGWGFQLQQPWFVAALAYLMFAVGLSLSGVFTLGTNLG
GIGQSLAARNGPLGDFFTGVLACVVASPCIAPFMGTALAYAFTAPALLAMLVFLALGLGLALPFLLIGFVPSLARRLPTP
GAWMETLKQVLAFPMYLTAIWLLWVLGKQRGVDALALMLVGATLLALGLWCFERSRWKSHRLGMGLATAMLVLALVPVVA
VTRLSLPAATATEGVVAFSPQLLDRLRADNRVVFVNMTADWCVTCKANEKNVLSSAEFRDALRRVDAVYMKGDWTNVDPA
ISTFLDQHQAVGVPLYVVYGPGAPPAILPTVLTGAITEDALLRAAR

Sequences:

>Translated_766_residues
MRNRKPMTVLHRIAALCLLALAAFPALAISEKDLLPVDQAFALSATADSRDRIALNWKIAPGYYLYRHRISVKAGKGFAA
GELALPEGESKHDEFFGQVQTYRKQLQATLAGKADPAVQTAVLQVQYQGCADAGVCYPPQRREIRVDLPAADATGAQATA
APRENLGALVPRSAAGPRLFGAPGQTAGVDALPLPAEQAFNFEAIVGDGNSLLLRFTPAPGYYIYRDRTSLALEGASGVR
TGLPRWPQGKAHRDEHFGDVVVYFDQAEVTLPLLRDHPDPAHVTLVATFQGCQTDGICYPPMTRRVALDVPAGIVSPQNQ
AQASPLMISPLAAGQAPVEPAPAASTAGPVADASAGNPERTPPPHTDKGLLGMLVLALLGGLVLNLMPCVLPILSLKVLG
LAHSGESRGHARSHATWYSLGVLVSFAAIGGLVIGLRAAGQAAGWGFQLQQPWFVAALAYLMFAVGLSLSGVFTLGTNLG
GIGQSLAARNGPLGDFFTGVLACVVASPCIAPFMGTALAYAFTAPALLAMLVFLALGLGLALPFLLIGFVPSLARRLPTP
GAWMETLKQVLAFPMYLTAIWLLWVLGKQRGVDALALMLVGATLLALGLWCFERSRWKSHRLGMGLATAMLVLALVPVVA
VTRLSLPAATATEGVVAFSPQLLDRLRADNRVVFVNMTADWCVTCKANEKNVLSSAEFRDALRRVDAVYMKGDWTNVDPA
ISTFLDQHQAVGVPLYVVYGPGAPPAILPTVLTGAITEDALLRAAR
>Mature_766_residues
MRNRKPMTVLHRIAALCLLALAAFPALAISEKDLLPVDQAFALSATADSRDRIALNWKIAPGYYLYRHRISVKAGKGFAA
GELALPEGESKHDEFFGQVQTYRKQLQATLAGKADPAVQTAVLQVQYQGCADAGVCYPPQRREIRVDLPAADATGAQATA
APRENLGALVPRSAAGPRLFGAPGQTAGVDALPLPAEQAFNFEAIVGDGNSLLLRFTPAPGYYIYRDRTSLALEGASGVR
TGLPRWPQGKAHRDEHFGDVVVYFDQAEVTLPLLRDHPDPAHVTLVATFQGCQTDGICYPPMTRRVALDVPAGIVSPQNQ
AQASPLMISPLAAGQAPVEPAPAASTAGPVADASAGNPERTPPPHTDKGLLGMLVLALLGGLVLNLMPCVLPILSLKVLG
LAHSGESRGHARSHATWYSLGVLVSFAAIGGLVIGLRAAGQAAGWGFQLQQPWFVAALAYLMFAVGLSLSGVFTLGTNLG
GIGQSLAARNGPLGDFFTGVLACVVASPCIAPFMGTALAYAFTAPALLAMLVFLALGLGLALPFLLIGFVPSLARRLPTP
GAWMETLKQVLAFPMYLTAIWLLWVLGKQRGVDALALMLVGATLLALGLWCFERSRWKSHRLGMGLATAMLVLALVPVVA
VTRLSLPAATATEGVVAFSPQLLDRLRADNRVVFVNMTADWCVTCKANEKNVLSSAEFRDALRRVDAVYMKGDWTNVDPA
ISTFLDQHQAVGVPLYVVYGPGAPPAILPTVLTGAITEDALLRAAR

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=582, Percent_Identity=28.0068728522337, Blast_Score=139, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 81015; Mature: 81015

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNRKPMTVLHRIAALCLLALAAFPALAISEKDLLPVDQAFALSATADSRDRIALNWKIA
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEECCCCCCEEEEEEEEC
PGYYLYRHRISVKAGKGFAAGELALPEGESKHDEFFGQVQTYRKQLQATLAGKADPAVQT
CCEEEEEEEEEEECCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHE
AVLQVQYQGCADAGVCYPPQRREIRVDLPAADATGAQATAAPRENLGALVPRSAAGPRLF
EEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCEE
GAPGQTAGVDALPLPAEQAFNFEAIVGDGNSLLLRFTPAPGYYIYRDRTSLALEGASGVR
CCCCCCCCCCCCCCCHHHCCCEEEEEECCCEEEEEEECCCCEEEEECCCEEEEECCCCHH
TGLPRWPQGKAHRDEHFGDVVVYFDQAEVTLPLLRDHPDPAHVTLVATFQGCQTDGICYP
CCCCCCCCCCCCCCCCCCCEEEEEECCCEEEHHHHCCCCCCEEEEEEEECCCCCCCEECC
PMTRRVALDVPAGIVSPQNQAQASPLMISPLAAGQAPVEPAPAASTAGPVADASAGNPER
CCCCEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TPPPHTDKGLLGMLVLALLGGLVLNLMPCVLPILSLKVLGLAHSGESRGHARSHATWYSL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHH
GVLVSFAAIGGLVIGLRAAGQAAGWGFQLQQPWFVAALAYLMFAVGLSLSGVFTLGTNLG
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCC
GIGQSLAARNGPLGDFFTGVLACVVASPCIAPFMGTALAYAFTAPALLAMLVFLALGLGL
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALPFLLIGFVPSLARRLPTPGAWMETLKQVLAFPMYLTAIWLLWVLGKQRGVDALALMLV
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GATLLALGLWCFERSRWKSHRLGMGLATAMLVLALVPVVAVTRLSLPAATATEGVVAFSP
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECH
QLLDRLRADNRVVFVNMTADWCVTCKANEKNVLSSAEFRDALRRVDAVYMKGDWTNVDPA
HHHHHHCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCHH
ISTFLDQHQAVGVPLYVVYGPGAPPAILPTVLTGAITEDALLRAAR
HHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRNRKPMTVLHRIAALCLLALAAFPALAISEKDLLPVDQAFALSATADSRDRIALNWKIA
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEECCCCCCEEEEEEEEC
PGYYLYRHRISVKAGKGFAAGELALPEGESKHDEFFGQVQTYRKQLQATLAGKADPAVQT
CCEEEEEEEEEEECCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHE
AVLQVQYQGCADAGVCYPPQRREIRVDLPAADATGAQATAAPRENLGALVPRSAAGPRLF
EEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCEE
GAPGQTAGVDALPLPAEQAFNFEAIVGDGNSLLLRFTPAPGYYIYRDRTSLALEGASGVR
CCCCCCCCCCCCCCCHHHCCCEEEEEECCCEEEEEEECCCCEEEEECCCEEEEECCCCHH
TGLPRWPQGKAHRDEHFGDVVVYFDQAEVTLPLLRDHPDPAHVTLVATFQGCQTDGICYP
CCCCCCCCCCCCCCCCCCCEEEEEECCCEEEHHHHCCCCCCEEEEEEEECCCCCCCEECC
PMTRRVALDVPAGIVSPQNQAQASPLMISPLAAGQAPVEPAPAASTAGPVADASAGNPER
CCCCEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TPPPHTDKGLLGMLVLALLGGLVLNLMPCVLPILSLKVLGLAHSGESRGHARSHATWYSL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHH
GVLVSFAAIGGLVIGLRAAGQAAGWGFQLQQPWFVAALAYLMFAVGLSLSGVFTLGTNLG
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCC
GIGQSLAARNGPLGDFFTGVLACVVASPCIAPFMGTALAYAFTAPALLAMLVFLALGLGL
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALPFLLIGFVPSLARRLPTPGAWMETLKQVLAFPMYLTAIWLLWVLGKQRGVDALALMLV
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GATLLALGLWCFERSRWKSHRLGMGLATAMLVLALVPVVAVTRLSLPAATATEGVVAFSP
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECH
QLLDRLRADNRVVFVNMTADWCVTCKANEKNVLSSAEFRDALRRVDAVYMKGDWTNVDPA
HHHHHHCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCHH
ISTFLDQHQAVGVPLYVVYGPGAPPAILPTVLTGAITEDALLRAAR
HHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA