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The map label for this gene is trpD

Identifier: 21241253

GI number: 21241253

Start: 570522

End: 571559

Strand: Direct

Name: trpD

Synonym: XAC0480

Alternate gene names: 21241253

Gene position: 570522-571559 (Clockwise)

Preceding gene: 21241252

Following gene: 21241254

Centisome position: 11.02

GC content: 65.41

Gene sequence:

>1038_bases
ATGCCCATCACTCCGCAAGAAGCCCTGCAACGCACCATCGAACACCGCGAAATCTTCCACGACGAAATGGTCGAGTTGAT
GCGGCAGATCATGCGCGGCGAGGTCTCCGACATGATGGTCGCGGCCATCCTCACCGGGCTACGAGTCAAGAAGGAAACCA
TCGGCGAAATTGCCGGCGCCGCCACGGTGATGCGCGAGTTCTCGCGCCGCGTGGACGTGGCCGATCGCCAGCACATGGTC
GACATCGTCGGCACCGGCGGCGATGGTTCGCATACCTTCAACATCTCCACCTGCGCCATGTTCGTCGCCGCAGCCGGCGG
TGCCAAGGTGGCCAAGCATGGCAATCGCAGCGTCTCGTCCAAATCCGGCAGTGCCGACGCACTGGAAGCATTGGGCGCGG
TGATCGAGCTGCAGCCCGAGCAGGTTGCCAGCGCGTTGGCGCACACCGGCATCGGCTTTATGTATGCGCCAGTGCATCAC
CCGGCCATGAAGGTGGTGGCGCCGGTGCGACGCGAAATGGGTGTGCGCACCATCTTCAACATTCTTGGCCCGCTGACAAA
CCCGGCGGGCTCGCCGAACATCCTGATGGGTGTGTTCCATCCGGATCTGGTCGGCATCCAGGCGCGTGTGCTGCAGGAGC
TTGGCGCCGAGCGCGCGCTGGTGGTGTGGGGGCGCGACGGCATGGACGAACTCTCGCTTGGCGCCGGCACCCTGGTCGGC
GAACTGCGCGACGGCCAGGTACGCGAATACGAAGTGCACCCGGAAGATTTCGGCATCGCCATGTCGGCCAGCCGTAACCT
CAAGGTGGCCGATGCTGCGCAATCGCGCGCGATGTTGCTGCAGGTATTGGACAACGTGCCCGGCCCCGCGCTGGATATCG
TGGCGCTCAACGCCGGTGCTGCGTTGTACGTGGCCGGCGTCGCCGACAGCATTGCTGATGGCGTACTTCGGGCACGCGCG
GTCATCGCCGACGGCTCGGCGCGCGCGCGCCTGGACGCCTATGTGGTCTACACCCGCCAGCTCGCCGTGCAGCCCTGA

Upstream 100 bases:

>100_bases
CGGCAGCCGCGCCGCTTGGTGCTTGCGCCTTCCTGCGCTGATCGCGCGCGCTGCAAGCTGCCTGCGTCTTCATCCATCAC
GTTCTGCCACGGTTGTTCCC

Downstream 100 bases:

>100_bases
GCCATGCCGGCAACCCCCACGCAGCAGCCATTACCCGCCGGCATCCTCACAGTCGCGCTGGCATGCTGCGTGCTGGCGCG
CAGCCGCTCTCCAGTGCGGC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MPITPQEALQRTIEHREIFHDEMVELMRQIMRGEVSDMMVAAILTGLRVKKETIGEIAGAATVMREFSRRVDVADRQHMV
DIVGTGGDGSHTFNISTCAMFVAAAGGAKVAKHGNRSVSSKSGSADALEALGAVIELQPEQVASALAHTGIGFMYAPVHH
PAMKVVAPVRREMGVRTIFNILGPLTNPAGSPNILMGVFHPDLVGIQARVLQELGAERALVVWGRDGMDELSLGAGTLVG
ELRDGQVREYEVHPEDFGIAMSASRNLKVADAAQSRAMLLQVLDNVPGPALDIVALNAGAALYVAGVADSIADGVLRARA
VIADGSARARLDAYVVYTRQLAVQP

Sequences:

>Translated_345_residues
MPITPQEALQRTIEHREIFHDEMVELMRQIMRGEVSDMMVAAILTGLRVKKETIGEIAGAATVMREFSRRVDVADRQHMV
DIVGTGGDGSHTFNISTCAMFVAAAGGAKVAKHGNRSVSSKSGSADALEALGAVIELQPEQVASALAHTGIGFMYAPVHH
PAMKVVAPVRREMGVRTIFNILGPLTNPAGSPNILMGVFHPDLVGIQARVLQELGAERALVVWGRDGMDELSLGAGTLVG
ELRDGQVREYEVHPEDFGIAMSASRNLKVADAAQSRAMLLQVLDNVPGPALDIVALNAGAALYVAGVADSIADGVLRARA
VIADGSARARLDAYVVYTRQLAVQP
>Mature_344_residues
PITPQEALQRTIEHREIFHDEMVELMRQIMRGEVSDMMVAAILTGLRVKKETIGEIAGAATVMREFSRRVDVADRQHMVD
IVGTGGDGSHTFNISTCAMFVAAAGGAKVAKHGNRSVSSKSGSADALEALGAVIELQPEQVASALAHTGIGFMYAPVHHP
AMKVVAPVRREMGVRTIFNILGPLTNPAGSPNILMGVFHPDLVGIQARVLQELGAERALVVWGRDGMDELSLGAGTLVGE
LRDGQVREYEVHPEDFGIAMSASRNLKVADAAQSRAMLLQVLDNVPGPALDIVALNAGAALYVAGVADSIADGVLRARAV
IADGSARARLDAYVVYTRQLAVQP

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=280, Percent_Identity=42.5, Blast_Score=196, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6320561, Length=356, Percent_Identity=28.3707865168539, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_XANAC (Q8PQ48)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_640835.1
- ProteinModelPortal:   Q8PQ48
- SMR:   Q8PQ48
- GeneID:   1154551
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC0480
- NMPDR:   fig|190486.1.peg.479
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- ProtClustDB:   PRK00188
- BioCyc:   XAXO190486:XAC0480-MONOMER
- BRENDA:   2.4.2.18
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36640; Mature: 36509

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPITPQEALQRTIEHREIFHDEMVELMRQIMRGEVSDMMVAAILTGLRVKKETIGEIAGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ATVMREFSRRVDVADRQHMVDIVGTGGDGSHTFNISTCAMFVAAAGGAKVAKHGNRSVSS
HHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEHHHHHHHHHHCCCCHHHHCCCCCCCC
KSGSADALEALGAVIELQPEQVASALAHTGIGFMYAPVHHPAMKVVAPVRREMGVRTIFN
CCCCHHHHHHHHHHHEECHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
ILGPLTNPAGSPNILMGVFHPDLVGIQARVLQELGAERALVVWGRDGMDELSLGAGTLVG
HHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHCCCHHHEE
ELRDGQVREYEVHPEDFGIAMSASRNLKVADAAQSRAMLLQVLDNVPGPALDIVALNAGA
CCCCCCEEEEEECCCCCCEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
ALYVAGVADSIADGVLRARAVIADGSARARLDAYVVYTRQLAVQP
EEEEEHHHHHHHHHHHHHHHHEECCCCCHHHHEEEEEEEHHCCCC
>Mature Secondary Structure 
PITPQEALQRTIEHREIFHDEMVELMRQIMRGEVSDMMVAAILTGLRVKKETIGEIAGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ATVMREFSRRVDVADRQHMVDIVGTGGDGSHTFNISTCAMFVAAAGGAKVAKHGNRSVSS
HHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEHHHHHHHHHHCCCCHHHHCCCCCCCC
KSGSADALEALGAVIELQPEQVASALAHTGIGFMYAPVHHPAMKVVAPVRREMGVRTIFN
CCCCHHHHHHHHHHHEECHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
ILGPLTNPAGSPNILMGVFHPDLVGIQARVLQELGAERALVVWGRDGMDELSLGAGTLVG
HHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHCCCHHHEE
ELRDGQVREYEVHPEDFGIAMSASRNLKVADAAQSRAMLLQVLDNVPGPALDIVALNAGA
CCCCCCEEEEEECCCCCCEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
ALYVAGVADSIADGVLRARAVIADGSARARLDAYVVYTRQLAVQP
EEEEEHHHHHHHHHHHHHHHHEECCCCCHHHHEEEEEEEHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217