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The map label for this gene is smeR [H]

Identifier: 21241099

GI number: 21241099

Start: 386341

End: 387024

Strand: Reverse

Name: smeR [H]

Synonym: XAC0325

Alternate gene names: 21241099

Gene position: 387024-386341 (Counterclockwise)

Preceding gene: 21241100

Following gene: 21241092

Centisome position: 7.48

GC content: 69.74

Gene sequence:

>684_bases
ATGAGCAGCGCGTCCCCGATCGGGCATGTGCTGATCGTCGAGGACGAACCGCGCCTGGCCGCGGTGTTGGGCGAGTACCT
GCACGCGGCCGGCTATTCGCACGACTGGATCGCCGATGGCGCGCAAGCGCTGGGCGCATTCCGCGCGCAGCAGCCCGACC
TGGTGCTACTGGACCTGATGCTGCCCAACCGCGGCGGCCTGGACATCTGCCGCGACCTGCGCAATGAAAGCGCGGTGCCG
GTCATCATGGTCACCGCGCGCGTGGAGGAAATCGACCGCCTGCTGGGCCTGGAGATCGGCGCGGACGACTACATCTGCAA
GCCGTTCAGCCCGCGCGAAGTGGTGGCGCGCGTCCAGGCAGTGTTGCGCCGGCATCGCCACGACCCCCACGGCGCGCCGG
CACCGGGCCTGCAGATCGACGAGGACGCCTGTCGCGCCAGCGTGGACGGCCGCGCCCTGGACCTGACCCAGGTCGAATTC
CGCCTGCTGCGTACCCTCGCCGCGGCCCCGGGGCGGGTGTACTCGCGCGAGCAACTGATGGGCCGGCTTTACGCCGACCA
CCGCATCGTCACCGACCGCACTGTCGACAGCCACGTCAAGAATCTACGCCGCAAACTCGCCGACGCCGGCGGCGAGGACT
GGGTCCGTTCGGTCTATGGGGCGGGGTATCGCTTTGAGCCGTGA

Upstream 100 bases:

>100_bases
TCTGCCGCAACATCGCCGAGGCACATGGCGGCTCGATCCACGCCGAGGCTTCGGCACTGGGCGGGCTGCGCATGGTGCTG
CGCCTGCCGGCGCTGGTCGC

Downstream 100 bases:

>100_bases
ATGGGGAATTGGGAATGGGGAATCGGTAGGGGGCTGCTGCGTCTCTTCGGCGCGTCTGACGCTTGTAGTTTCACATCGAC
TTGCGGAACGAAACTGTCCG

Product: two-component system regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MSSASPIGHVLIVEDEPRLAAVLGEYLHAAGYSHDWIADGAQALGAFRAQQPDLVLLDLMLPNRGGLDICRDLRNESAVP
VIMVTARVEEIDRLLGLEIGADDYICKPFSPREVVARVQAVLRRHRHDPHGAPAPGLQIDEDACRASVDGRALDLTQVEF
RLLRTLAAAPGRVYSREQLMGRLYADHRIVTDRTVDSHVKNLRRKLADAGGEDWVRSVYGAGYRFEP

Sequences:

>Translated_227_residues
MSSASPIGHVLIVEDEPRLAAVLGEYLHAAGYSHDWIADGAQALGAFRAQQPDLVLLDLMLPNRGGLDICRDLRNESAVP
VIMVTARVEEIDRLLGLEIGADDYICKPFSPREVVARVQAVLRRHRHDPHGAPAPGLQIDEDACRASVDGRALDLTQVEF
RLLRTLAAAPGRVYSREQLMGRLYADHRIVTDRTVDSHVKNLRRKLADAGGEDWVRSVYGAGYRFEP
>Mature_226_residues
SSASPIGHVLIVEDEPRLAAVLGEYLHAAGYSHDWIADGAQALGAFRAQQPDLVLLDLMLPNRGGLDICRDLRNESAVPV
IMVTARVEEIDRLLGLEIGADDYICKPFSPREVVARVQAVLRRHRHDPHGAPAPGLQIDEDACRASVDGRALDLTQVEFR
LLRTLAAAPGRVYSREQLMGRLYADHRIVTDRTVDSHVKNLRRKLADAGGEDWVRSVYGAGYRFEP

Specific function: Member of the two-component regulatory system BaeS/BaeR. Activates the mdtABCD operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=57.6576576576577, Blast_Score=249, Evalue=1e-67,
Organism=Escherichia coli, GI1790860, Length=203, Percent_Identity=46.3054187192118, Blast_Score=165, Evalue=2e-42,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=40.8071748878924, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=39.647577092511, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=37.5545851528384, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=36.8888888888889, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1789402, Length=216, Percent_Identity=37.962962962963, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=32.7510917030568, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI87082012, Length=217, Percent_Identity=34.5622119815668, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=35.1111111111111, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=29.3617021276596, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790552, Length=216, Percent_Identity=33.7962962962963, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=31.6742081447964, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788550, Length=120, Percent_Identity=32.5, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25106; Mature: 24975

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSASPIGHVLIVEDEPRLAAVLGEYLHAAGYSHDWIADGAQALGAFRAQQPDLVLLDLM
CCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEE
LPNRGGLDICRDLRNESAVPVIMVTARVEEIDRLLGLEIGADDYICKPFSPREVVARVQA
CCCCCCHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHH
VLRRHRHDPHGAPAPGLQIDEDACRASVDGRALDLTQVEFRLLRTLAAAPGRVYSREQLM
HHHHHCCCCCCCCCCCCEECHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCCCHHHHHHHH
GRLYADHRIVTDRTVDSHVKNLRRKLADAGGEDWVRSVYGAGYRFEP
HHHHHCCEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SSASPIGHVLIVEDEPRLAAVLGEYLHAAGYSHDWIADGAQALGAFRAQQPDLVLLDLM
CCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEE
LPNRGGLDICRDLRNESAVPVIMVTARVEEIDRLLGLEIGADDYICKPFSPREVVARVQA
CCCCCCHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHH
VLRRHRHDPHGAPAPGLQIDEDACRASVDGRALDLTQVEFRLLRTLAAAPGRVYSREQLM
HHHHHCCCCCCCCCCCCEECHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCCCHHHHHHHH
GRLYADHRIVTDRTVDSHVKNLRRKLADAGGEDWVRSVYGAGYRFEP
HHHHHCCEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]