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The map label for this gene is bkdR [H]

Identifier: 21240949

GI number: 21240949

Start: 215008

End: 215490

Strand: Direct

Name: bkdR [H]

Synonym: XAC0175

Alternate gene names: 21240949

Gene position: 215008-215490 (Clockwise)

Preceding gene: 21240946

Following gene: 77748514

Centisome position: 4.15

GC content: 66.67

Gene sequence:

>483_bases
ATGGATCAGCCCATCGCCTTGGACCGCACCGATTTGCGCCTGCTCGCCCTGCTGCAGACGCAGGGGCGCAGCAGCAATGC
GGAGCTGGCCGTGCAGGTCAATCTGTCGGCGTCTGCATGCCTGCGCCGCACGCAGCGACTGGAAGCCGCCGGCATCATCG
CCGGCTATGGCGCGCGGCTGGATGCGCGCGCGCTAGGGCTGGGCTTGCAGGCGTTCGTGCGTGTGCAGCTGGAGCAGCAC
GGGCAAGCCGACATCGAGCATTTCGCCGAGGGCGTGCGCGGCTGGGACGAGGTGGTGGCGTGTTGGGCGCTGACCGGCGA
CATGGATTACCTGTTGCAGGTACAGGTGCGCGACCTGGAACACTTCTCGCGGTTTCTGCTCGATCGCCTGCTCAATGCCA
CGGGCGTGTCGGATGTGAATTCCAGCTTCGTGCTGCGCACGGTGAAGGCGCCGGAAGGTCTGCCGCTGTCGCATCTGGCC
TGA

Upstream 100 bases:

>100_bases
TCACCTTAGCCGGATGTCCGCGCAACGGGATTGCGAATCTTGCGTGCCATGTGCATCTTGGCGCAAGATCCGTGCGTCAT
CCTCTGCTGCTGCGCAACAT

Downstream 100 bases:

>100_bases
AGTGCAGATCAGCCATGTGGCTTAGGGCAGGGCGCCGCTCGCCCGGTGCAGCCGGCAAGGTGCACCGGCGTGCCGTCGCT
TTCCAGACGGACGCAAGAAA

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MDQPIALDRTDLRLLALLQTQGRSSNAELAVQVNLSASACLRRTQRLEAAGIIAGYGARLDARALGLGLQAFVRVQLEQH
GQADIEHFAEGVRGWDEVVACWALTGDMDYLLQVQVRDLEHFSRFLLDRLLNATGVSDVNSSFVLRTVKAPEGLPLSHLA

Sequences:

>Translated_160_residues
MDQPIALDRTDLRLLALLQTQGRSSNAELAVQVNLSASACLRRTQRLEAAGIIAGYGARLDARALGLGLQAFVRVQLEQH
GQADIEHFAEGVRGWDEVVACWALTGDMDYLLQVQVRDLEHFSRFLLDRLLNATGVSDVNSSFVLRTVKAPEGLPLSHLA
>Mature_160_residues
MDQPIALDRTDLRLLALLQTQGRSSNAELAVQVNLSASACLRRTQRLEAAGIIAGYGARLDARALGLGLQAFVRVQLEQH
GQADIEHFAEGVRGWDEVVACWALTGDMDYLLQVQVRDLEHFSRFLLDRLLNATGVSDVNSSFVLRTVKAPEGLPLSHLA

Specific function: Positive regulator of the bkd operon for branched-chain keto acid dehydrogenase complex [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081742, Length=151, Percent_Identity=40.3973509933775, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1787116, Length=143, Percent_Identity=38.4615384615385, Blast_Score=101, Evalue=2e-23,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17534; Mature: 17534

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQPIALDRTDLRLLALLQTQGRSSNAELAVQVNLSASACLRRTQRLEAAGIIAGYGARL
CCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHEEECCCCCC
DARALGLGLQAFVRVQLEQHGQADIEHFAEGVRGWDEVVACWALTGDMDYLLQVQVRDLE
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHH
HFSRFLLDRLLNATGVSDVNSSFVLRTVKAPEGLPLSHLA
HHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHCCC
>Mature Secondary Structure
MDQPIALDRTDLRLLALLQTQGRSSNAELAVQVNLSASACLRRTQRLEAAGIIAGYGARL
CCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHEEECCCCCC
DARALGLGLQAFVRVQLEQHGQADIEHFAEGVRGWDEVVACWALTGDMDYLLQVQVRDLE
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHH
HFSRFLLDRLLNATGVSDVNSSFVLRTVKAPEGLPLSHLA
HHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8320210 [H]