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The map label for this gene is exuR [H]

Identifier: 21240940

GI number: 21240940

Start: 205185

End: 206213

Strand: Direct

Name: exuR [H]

Synonym: XAC0166

Alternate gene names: 21240940

Gene position: 205185-206213 (Clockwise)

Preceding gene: 21240939

Following gene: 21240941

Centisome position: 3.96

GC content: 69.1

Gene sequence:

>1029_bases
ATGCCTGGCCTGCCGAAGGGTCGGGTCGCAACGATCAACGACATCGCGCGGATGTCGGGCGTGTCCAAGAAGACCGTCTC
GCGGATCATCAACAATTCGCCACTGGTGCGCCAGGACACGCGCGAGAAGGTCGAGGCGCTGATGCGCGAGGTCGGCTACG
CGCCGGATCCGCTCGCGCGTGGGCTGGCGTTCCGGCGCTCGTTCCTGATCGGTATGGTCTACGACAACCCCACCGCGCAA
TACATCGTGGACATGCAGTACGGCGCGCTGGACGCACTGCGCGGCTCCAGCTTCGAGCTGGTGGTGCACCCCTGCGACAG
CCGCAGCCCCGGCTACATCGAAGGCGTGCGCCGTTTCGCCCAGGCGCAGAAGCTGCACGGCGTGATCCTGGTGCCACGCG
CCTCCGAAGACCAGGCGCTGGCCGACATGCTGGCCGAGATCGGTTGCCGTTACACCCGCATCGCCTCGATCGCGCTGGAC
GCCACCTCGCAGACGGTCATCACCCACGACCGCGACGGGGCAGCGGAGGCGGCCGATTACCTGCTCTCGCTGGGCCACCG
CGACATCGCCCTGGTCACCGGCCCCAGCGCCTACCGCTCCTCGATCGAGCGCACCTCCGGATTTGCCGACGCGCTGACCC
GGCGCGGCATCGAGCTGCCGCCCGAGCGCATCGTCGAAGCCGGTTACACCTTCGAATCCGGCGTGGCGGCGGCCGAAAAG
CTGCTGCTGGGCAAGAAACGGCCCACCGCCATCTTCACCGGTAACGACGAAATGGCCGCCGGTATCTACAAGGTCGCCCT
GCGCGCCGGCATCAACATCCCGCGCCAGCTCTCGGTGATCGGCTACGACGACAGTTCGCTGGCCTCGCGCCTGTGGCCGC
CGCTGACCTCGGTGCGCCGCCACACCCGCGACACCGGCCGCACCGCCGCGGCGATGCTGATCCAGCCCGACAACGCGCCG
CAGCTGCCCACCGCCAGCGTGCGGCCGCACCTGATCGTGCGCGACTCCTGCCAGCCGCCGGAGGATTGA

Upstream 100 bases:

>100_bases
CGGCAGGCCTCGCTCAGGTCTGCCGGCCGTCGGGCCGGTAGAATCCAATCAACTTTACTGGTTGACCGCTATGCCCGCCC
GCAAGATGCCTGAAGAGGGA

Downstream 100 bases:

>100_bases
TCGCCGCGCCGCGCGGGTTCAATCTTCCGGCGCTACGCGCCATCTTCTTCCCAGGAAGAGGGAACAAGCCTCCGCTCGGC
CAGCGGCTGGCCCCCATCCG

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Probable galacturonate locus repressor [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MPGLPKGRVATINDIARMSGVSKKTVSRIINNSPLVRQDTREKVEALMREVGYAPDPLARGLAFRRSFLIGMVYDNPTAQ
YIVDMQYGALDALRGSSFELVVHPCDSRSPGYIEGVRRFAQAQKLHGVILVPRASEDQALADMLAEIGCRYTRIASIALD
ATSQTVITHDRDGAAEAADYLLSLGHRDIALVTGPSAYRSSIERTSGFADALTRRGIELPPERIVEAGYTFESGVAAAEK
LLLGKKRPTAIFTGNDEMAAGIYKVALRAGINIPRQLSVIGYDDSSLASRLWPPLTSVRRHTRDTGRTAAAMLIQPDNAP
QLPTASVRPHLIVRDSCQPPED

Sequences:

>Translated_342_residues
MPGLPKGRVATINDIARMSGVSKKTVSRIINNSPLVRQDTREKVEALMREVGYAPDPLARGLAFRRSFLIGMVYDNPTAQ
YIVDMQYGALDALRGSSFELVVHPCDSRSPGYIEGVRRFAQAQKLHGVILVPRASEDQALADMLAEIGCRYTRIASIALD
ATSQTVITHDRDGAAEAADYLLSLGHRDIALVTGPSAYRSSIERTSGFADALTRRGIELPPERIVEAGYTFESGVAAAEK
LLLGKKRPTAIFTGNDEMAAGIYKVALRAGINIPRQLSVIGYDDSSLASRLWPPLTSVRRHTRDTGRTAAAMLIQPDNAP
QLPTASVRPHLIVRDSCQPPED
>Mature_341_residues
PGLPKGRVATINDIARMSGVSKKTVSRIINNSPLVRQDTREKVEALMREVGYAPDPLARGLAFRRSFLIGMVYDNPTAQY
IVDMQYGALDALRGSSFELVVHPCDSRSPGYIEGVRRFAQAQKLHGVILVPRASEDQALADMLAEIGCRYTRIASIALDA
TSQTVITHDRDGAAEAADYLLSLGHRDIALVTGPSAYRSSIERTSGFADALTRRGIELPPERIVEAGYTFESGVAAAEKL
LLGKKRPTAIFTGNDEMAAGIYKVALRAGINIPRQLSVIGYDDSSLASRLWPPLTSVRRHTRDTGRTAAAMLIQPDNAPQ
LPTASVRPHLIVRDSCQPPED

Specific function: Transcriptional repressor for the exu locus which is required for galacturonate utilization (Probable) [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=319, Percent_Identity=30.7210031347962, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1787948, Length=340, Percent_Identity=30.2941176470588, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1786540, Length=313, Percent_Identity=31.9488817891374, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1790369, Length=315, Percent_Identity=28.2539682539683, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1789068, Length=358, Percent_Identity=28.7709497206704, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787580, Length=319, Percent_Identity=25.705329153605, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1788474, Length=314, Percent_Identity=32.484076433121, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789202, Length=300, Percent_Identity=31.3333333333333, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1786268, Length=326, Percent_Identity=23.9263803680982, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1790715, Length=305, Percent_Identity=21.9672131147541, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787906, Length=322, Percent_Identity=23.9130434782609, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI48994940, Length=293, Percent_Identity=21.8430034129693, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37192; Mature: 37061

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGLPKGRVATINDIARMSGVSKKTVSRIINNSPLVRQDTREKVEALMREVGYAPDPLAR
CCCCCCCCEEHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHH
GLAFRRSFLIGMVYDNPTAQYIVDMQYGALDALRGSSFELVVHPCDSRSPGYIEGVRRFA
HHHHHHHHEEEEEECCCCEEEEEEECCCCHHHHCCCCEEEEEECCCCCCCHHHHHHHHHH
QAQKLHGVILVPRASEDQALADMLAEIGCRYTRIASIALDATSQTVITHDRDGAAEAADY
HHHHHCCEEEEECCCCHHHHHHHHHHHCCCHHHHHHEEECCCCCEEEEECCCCHHHHHHH
LLSLGHRDIALVTGPSAYRSSIERTSGFADALTRRGIELPPERIVEAGYTFESGVAAAEK
HHHCCCCCEEEEECCHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHH
LLLGKKRPTAIFTGNDEMAAGIYKVALRAGINIPRQLSVIGYDDSSLASRLWPPLTSVRR
HHHCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHCCCHHHHHH
HTRDTGRTAAAMLIQPDNAPQLPTASVRPHLIVRDSCQPPED
HHHHCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
PGLPKGRVATINDIARMSGVSKKTVSRIINNSPLVRQDTREKVEALMREVGYAPDPLAR
CCCCCCCEEHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHH
GLAFRRSFLIGMVYDNPTAQYIVDMQYGALDALRGSSFELVVHPCDSRSPGYIEGVRRFA
HHHHHHHHEEEEEECCCCEEEEEEECCCCHHHHCCCCEEEEEECCCCCCCHHHHHHHHHH
QAQKLHGVILVPRASEDQALADMLAEIGCRYTRIASIALDATSQTVITHDRDGAAEAADY
HHHHHCCEEEEECCCCHHHHHHHHHHHCCCHHHHHHEEECCCCCEEEEECCCCHHHHHHH
LLSLGHRDIALVTGPSAYRSSIERTSGFADALTRRGIELPPERIVEAGYTFESGVAAAEK
HHHCCCCCEEEEECCHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHH
LLLGKKRPTAIFTGNDEMAAGIYKVALRAGINIPRQLSVIGYDDSSLASRLWPPLTSVRR
HHHCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHCCCHHHHHH
HTRDTGRTAAAMLIQPDNAPQLPTASVRPHLIVRDSCQPPED
HHHHCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]