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The map label for this gene is quiP [H]

Identifier: 21240811

GI number: 21240811

Start: 46368

End: 47507

Strand: Direct

Name: quiP [H]

Synonym: XAC0037

Alternate gene names: 21240811

Gene position: 46368-47507 (Clockwise)

Preceding gene: 21240809

Following gene: 21240813

Centisome position: 0.9

GC content: 64.91

Gene sequence:

>1140_bases
TTGACCGCTGGGGCGTGGCGCACCTCTATGCAAAGACCGACAACGACGCGTTCTTCGTGCAAGGCTTCAATGTGGCGCGC
GACCGCTTGGTTCAGCTGGATCTGCTGCGTCGCAAAGGCCTGGGCCACCTGTCGGAAGCGTTCGGGCCAACCTATGTGGC
GCAGGATCGTGCCGCGCGGCTGTTTCTGTATCAGCACCGCATTGCCGTGGTCGGAGAATCCCAAAGCCGGCTTCATCACC
ACGTCCAACGAAATGAATCTGCCCCGCGACGATCCGGTTGCGCAGCGCAAACTCGGTTTCGAGTGGGCCAACGACGCACG
CCATGCGCGCATCATCCAGGTGCTTTCGCAGCTGCCCAAGCCAAGGTTGGAGGATTCGGAAAAGTTGCAGAACGATCAGG
TCTCGTTGCCCGCGCAGCGCCTGGTCGCGTTGCTGCAACCGCTGCAGTCGCACGACCCTGACACCAGCGCCGCGCTCGCG
TTGCTGCGTCCCTGGAATGGCGACGCCAGCGCCGCGTCTGCCGCAGCCGCGCTGGAGGAAGTCTGGTTCAGTCGCTATCT
CGGCGATGCCTACAAGGCGTTGCGATTGCGCCCATCGGAAGCCGCCAGCTTCGGCGCGCCGGATGCTGCGGCCATGCTGG
ATGCGCTGGAACATCCCGGCGCGGCGTTCGGCGCCACTCCGGCCGCACGCCGCGACCAACTGCTGCTGGAGTCGTTGCGC
AACGCGTATCACGCATTGGGCTCCCTGCAAGGCCCCGATACCAGGCAGTGGCAGTGGGGCAACTTGCATACCAACAAGAT
CGCGCATGCGATGAGCGCGGTGGCCGGTGCCGACCGCGCCTTGCTCGATGTCGGCCCGTTTGCCAAGGGCGGTAGCCCGT
ACACGCCCAATCAATCCAGCTACGACCCTGCCGACTTTCGCCAGACCATCGGCCCGTCCGCACGCCTGATCATCGACCTG
AGCAACTGGGACAACGCGCGCGCCATGAATTTCCCAGGCCAGTCCGGCGACCCGGCCAGCCCGCACTATCGCGACCTCGC
ACCGCTCTGGCTAAACGGCAGCTACTTCCCGCTGCTGTATACGCGCGCTGCGGTGGATGCGGCAACCGAACAGATCTTCG
ACCTGGTGCCGGCGCAGTAG

Upstream 100 bases:

>100_bases
CCCCGCACTGCGCTGGCGCCGACAGCTGGGCGTGCAGCGGCCGCACCCAACCAGGCCACCCTGACGGTGGCAGGTCTCGG
GCAGCCGGCGCAGATCCGCA

Downstream 100 bases:

>100_bases
CGCAACGTCGAGTGACCCGAGGCAACGCACATTGCGCAGCAAGTACCAAAACGTCTCCGCGCTTGCTGCACCGCATGCAA
TCACGCTTTCGCGGTCGCCT

Product: penicillin acylase

Products: NA

Alternate protein names: AHL acylase quiP; Acyl-HSL acylase quiP; Acyl-HSL acylase quiP subunit alpha; Acyl-HSL acylase quiP subunit beta [H]

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MTAGAWRTSMQRPTTTRSSCKASMWRATAWFSWICCVAKAWATCRKRSGQPMWRRIVPRGCFCISTALPWSENPKAGFIT
TSNEMNLPRDDPVAQRKLGFEWANDARHARIIQVLSQLPKPRLEDSEKLQNDQVSLPAQRLVALLQPLQSHDPDTSAALA
LLRPWNGDASAASAAAALEEVWFSRYLGDAYKALRLRPSEAASFGAPDAAAMLDALEHPGAAFGATPAARRDQLLLESLR
NAYHALGSLQGPDTRQWQWGNLHTNKIAHAMSAVAGADRALLDVGPFAKGGSPYTPNQSSYDPADFRQTIGPSARLIIDL
SNWDNARAMNFPGQSGDPASPHYRDLAPLWLNGSYFPLLYTRAAVDAATEQIFDLVPAQ

Sequences:

>Translated_379_residues
MTAGAWRTSMQRPTTTRSSCKASMWRATAWFSWICCVAKAWATCRKRSGQPMWRRIVPRGCFCISTALPWSENPKAGFIT
TSNEMNLPRDDPVAQRKLGFEWANDARHARIIQVLSQLPKPRLEDSEKLQNDQVSLPAQRLVALLQPLQSHDPDTSAALA
LLRPWNGDASAASAAAALEEVWFSRYLGDAYKALRLRPSEAASFGAPDAAAMLDALEHPGAAFGATPAARRDQLLLESLR
NAYHALGSLQGPDTRQWQWGNLHTNKIAHAMSAVAGADRALLDVGPFAKGGSPYTPNQSSYDPADFRQTIGPSARLIIDL
SNWDNARAMNFPGQSGDPASPHYRDLAPLWLNGSYFPLLYTRAAVDAATEQIFDLVPAQ
>Mature_378_residues
TAGAWRTSMQRPTTTRSSCKASMWRATAWFSWICCVAKAWATCRKRSGQPMWRRIVPRGCFCISTALPWSENPKAGFITT
SNEMNLPRDDPVAQRKLGFEWANDARHARIIQVLSQLPKPRLEDSEKLQNDQVSLPAQRLVALLQPLQSHDPDTSAALAL
LRPWNGDASAASAAAALEEVWFSRYLGDAYKALRLRPSEAASFGAPDAAAMLDALEHPGAAFGATPAARRDQLLLESLRN
AYHALGSLQGPDTRQWQWGNLHTNKIAHAMSAVAGADRALLDVGPFAKGGSPYTPNQSSYDPADFRQTIGPSARLIIDLS
NWDNARAMNFPGQSGDPASPHYRDLAPLWLNGSYFPLLYTRAAVDAATEQIFDLVPAQ

Specific function: Catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid. Possesses a specificity for the degradation of long-chain acyl-HSLs (side chains of seven or more carbons in lengt

COG id: COG2366

COG function: function code R; Protein related to penicillin acylase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S45 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014395
- InterPro:   IPR002692 [H]

Pfam domain/function: PF01804 Penicil_amidase [H]

EC number: =3.5.1.97 [H]

Molecular weight: Translated: 41582; Mature: 41451

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAGAWRTSMQRPTTTRSSCKASMWRATAWFSWICCVAKAWATCRKRSGQPMWRRIVPRG
CCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCC
CFCISTALPWSENPKAGFITTSNEMNLPRDDPVAQRKLGFEWANDARHARIIQVLSQLPK
CEEEECCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHCCC
PRLEDSEKLQNDQVSLPAQRLVALLQPLQSHDPDTSAALALLRPWNGDASAASAAAALEE
CCCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHEEECCCCCHHHHHHHHHHHH
VWFSRYLGDAYKALRLRPSEAASFGAPDAAAMLDALEHPGAAFGATPAARRDQLLLESLR
HHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
NAYHALGSLQGPDTRQWQWGNLHTNKIAHAMSAVAGADRALLDVGPFAKGGSPYTPNQSS
HHHHHHHCCCCCCCCCEECCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCC
YDPADFRQTIGPSARLIIDLSNWDNARAMNFPGQSGDPASPHYRDLAPLWLNGSYFPLLY
CCHHHHHHHCCCCEEEEEEECCCCCCCEECCCCCCCCCCCCCHHCCCCEEECCCCHHHHH
TRAAVDAATEQIFDLVPAQ
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TAGAWRTSMQRPTTTRSSCKASMWRATAWFSWICCVAKAWATCRKRSGQPMWRRIVPRG
CCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCC
CFCISTALPWSENPKAGFITTSNEMNLPRDDPVAQRKLGFEWANDARHARIIQVLSQLPK
CEEEECCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHCCC
PRLEDSEKLQNDQVSLPAQRLVALLQPLQSHDPDTSAALALLRPWNGDASAASAAAALEE
CCCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHEEECCCCCHHHHHHHHHHHH
VWFSRYLGDAYKALRLRPSEAASFGAPDAAAMLDALEHPGAAFGATPAARRDQLLLESLR
HHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
NAYHALGSLQGPDTRQWQWGNLHTNKIAHAMSAVAGADRALLDVGPFAKGGSPYTPNQSS
HHHHHHHCCCCCCCCCEECCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCC
YDPADFRQTIGPSARLIIDLSNWDNARAMNFPGQSGDPASPHYRDLAPLWLNGSYFPLLY
CCHHHHHHHCCCCEEEEEEECCCCCCCEECCCCCCCCCCCCCHHCCCCEEECCCCHHHHH
TRAAVDAATEQIFDLVPAQ
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]