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The map label for this gene is yafC [H]

Identifier: 21240813

GI number: 21240813

Start: 48629

End: 49504

Strand: Direct

Name: yafC [H]

Synonym: XAC0039

Alternate gene names: 21240813

Gene position: 48629-49504 (Clockwise)

Preceding gene: 21240811

Following gene: 21240815

Centisome position: 0.94

GC content: 65.53

Gene sequence:

>876_bases
ATGGACCTCAATGCCCTGATCGATTTCGCGCTGGTGGCTGCAAACCAGGGGCTGGGAAAGGCCAGCCGCGCCAGTGGCAG
ATCGAAGGCGACCTTGTCGCGGCGGATTACCGAGCTTGAAGAGCAGCTGGGCGTGCGCCTGGTCGAGCGCAGCGCGCGCG
GCCTCAAGCTCACCGAGGCGGGGCAGCAGTTGATGGCCCGCACCGAAGTGCCGCTGAGCGAAGTGGCCGAAGCGATGACG
GCCGCACGCGAGGGGCTTTCGACACCGCGAGGGCGCTTACGTGTCGCGTCCCCGGTGTTGTTCTCGCAACTGGCGATGGG
ACGCATCGGCGCGGACTTCTGTGCGGCTTATCCCGAGATCACGCTCGAGGTGGTGGCCGAGGACCGCACGGTCGATCTGG
TGGAAGAACAGTTCGATGTCGCCATCCGCATCAACCCACGTCCGGACAGCAGCCTGGTCGGGCGCTGCTTCGCCAAGGAC
CGGCTGGTGGTGGTGGCCGCACCGTCTATCGCGATGCCGTCGGGTGATGCAATGCATCCGGTGCCGGGCGTGGTGATGTC
GAGTTTCCAGCCCACCACCTGGGTGCTGGATGATGGGCGCCTGGCGTTGGAGCCGGTCCCGCGGATGCAGTTTTCCTCGT
TCCTGATGGTGCGCGATGCGGTCATCGCCGGTGGCGGCGTCGCATTGATTCCGCAGTCGATTGCGTGGGAGCAGCTGGCA
CGCGGAGAATTGCTGCAGTGGGGCACCATCTCCGGCGTGGAGCCGGCGTTGTGGGTATTGCATACCTCCAGGCGCCTGGC
AGCGCCGAAAGTGCGTGCCTTCGTGGATTTCATCTGCGCCCGCTATCCGGACATGTCGCTGGTGTTGAAGGGGTAG

Upstream 100 bases:

>100_bases
CCGGCATGGTCGGTTCGTTGCGGTAGGGCAACGGTATGTCGTTGCGCCATCAGTACGAAGACGCCAGGATGTAGACGCCC
CGTTTCAGATGTGGAACACC

Downstream 100 bases:

>100_bases
GGCGATAGCGATCCTTACGATCGCCGATGAAGTATCGACAAATCCAGGCGGCAGCACGGGTGTGGAGCGAGGCCATCTGC
CACTACGTGGCCGCGATACA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MDLNALIDFALVAANQGLGKASRASGRSKATLSRRITELEEQLGVRLVERSARGLKLTEAGQQLMARTEVPLSEVAEAMT
AAREGLSTPRGRLRVASPVLFSQLAMGRIGADFCAAYPEITLEVVAEDRTVDLVEEQFDVAIRINPRPDSSLVGRCFAKD
RLVVVAAPSIAMPSGDAMHPVPGVVMSSFQPTTWVLDDGRLALEPVPRMQFSSFLMVRDAVIAGGGVALIPQSIAWEQLA
RGELLQWGTISGVEPALWVLHTSRRLAAPKVRAFVDFICARYPDMSLVLKG

Sequences:

>Translated_291_residues
MDLNALIDFALVAANQGLGKASRASGRSKATLSRRITELEEQLGVRLVERSARGLKLTEAGQQLMARTEVPLSEVAEAMT
AAREGLSTPRGRLRVASPVLFSQLAMGRIGADFCAAYPEITLEVVAEDRTVDLVEEQFDVAIRINPRPDSSLVGRCFAKD
RLVVVAAPSIAMPSGDAMHPVPGVVMSSFQPTTWVLDDGRLALEPVPRMQFSSFLMVRDAVIAGGGVALIPQSIAWEQLA
RGELLQWGTISGVEPALWVLHTSRRLAAPKVRAFVDFICARYPDMSLVLKG
>Mature_291_residues
MDLNALIDFALVAANQGLGKASRASGRSKATLSRRITELEEQLGVRLVERSARGLKLTEAGQQLMARTEVPLSEVAEAMT
AAREGLSTPRGRLRVASPVLFSQLAMGRIGADFCAAYPEITLEVVAEDRTVDLVEEQFDVAIRINPRPDSSLVGRCFAKD
RLVVVAAPSIAMPSGDAMHPVPGVVMSSFQPTTWVLDDGRLALEPVPRMQFSSFLMVRDAVIAGGGVALIPQSIAWEQLA
RGELLQWGTISGVEPALWVLHTSRRLAAPKVRAFVDFICARYPDMSLVLKG

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=282, Percent_Identity=30.1418439716312, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI87081978, Length=299, Percent_Identity=28.7625418060201, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1787128, Length=304, Percent_Identity=24.6710526315789, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI145693193, Length=302, Percent_Identity=25.8278145695364, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789440, Length=288, Percent_Identity=22.2222222222222, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789639, Length=251, Percent_Identity=27.0916334661355, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI157672245, Length=148, Percent_Identity=33.7837837837838, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1787589, Length=292, Percent_Identity=22.9452054794521, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787879, Length=301, Percent_Identity=26.9102990033223, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788481, Length=281, Percent_Identity=22.4199288256228, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788706, Length=170, Percent_Identity=27.0588235294118, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082132, Length=297, Percent_Identity=24.2424242424242, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31462; Mature: 31462

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLNALIDFALVAANQGLGKASRASGRSKATLSRRITELEEQLGVRLVERSARGLKLTEA
CCHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
GQQLMARTEVPLSEVAEAMTAAREGLSTPRGRLRVASPVLFSQLAMGRIGADFCAAYPEI
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHCCHHHHHHCCCE
TLEVVAEDRTVDLVEEQFDVAIRINPRPDSSLVGRCFAKDRLVVVAAPSIAMPSGDAMHP
EEEEEECCCHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCEEEEECCCEECCCCCCCCC
VPGVVMSSFQPTTWVLDDGRLALEPVPRMQFSSFLMVRDAVIAGGGVALIPQSIAWEQLA
CCHHHHHCCCCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHH
RGELLQWGTISGVEPALWVLHTSRRLAAPKVRAFVDFICARYPDMSLVLKG
CCCCCCCCCCCCCCHHHEEEECCCHHCCHHHHHHHHHHHHCCCCCEEEECC
>Mature Secondary Structure
MDLNALIDFALVAANQGLGKASRASGRSKATLSRRITELEEQLGVRLVERSARGLKLTEA
CCHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
GQQLMARTEVPLSEVAEAMTAAREGLSTPRGRLRVASPVLFSQLAMGRIGADFCAAYPEI
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHCCHHHHHHCCCE
TLEVVAEDRTVDLVEEQFDVAIRINPRPDSSLVGRCFAKDRLVVVAAPSIAMPSGDAMHP
EEEEEECCCHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCEEEEECCCEECCCCCCCCC
VPGVVMSSFQPTTWVLDDGRLALEPVPRMQFSSFLMVRDAVIAGGGVALIPQSIAWEQLA
CCHHHHHCCCCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHH
RGELLQWGTISGVEPALWVLHTSRRLAAPKVRAFVDFICARYPDMSLVLKG
CCCCCCCCCCCCCCHHHEEEECCCHHCCHHHHHHHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]