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The map label for this gene is arsB [H]

Identifier: 57238576

GI number: 57238576

Start: 1631624

End: 1632667

Strand: Direct

Name: arsB [H]

Synonym: CJE1733

Alternate gene names: 57238576

Gene position: 1631624-1632667 (Clockwise)

Preceding gene: 57238575

Following gene: 57238577

Centisome position: 91.78

GC content: 30.94

Gene sequence:

>1044_bases
ATGTTAGGTTTTATCGATAGATTTCTCACGCTTTGGATATTTTTAGCTATTTTTTTGGGTTTAATTTTAGGTATCATTTT
CCCCAATATCGCTTTATTTTGGAATTTATTTGAGTACAAGTCTGTAAATGTAGTATTGACTTTATGTCTTATTTTGATGA
TGTATCCGCCTTTGGCTAAGGTTGATTATGCAAAGCTTTCAAAGGTATTTGATTCTAAAAAAGTTATCTTGCTTTCTATG
ATTTTAAATTGGTTTATAGGCCCTTTGCTTATGTTTATCTTAGCTTTTATTTTCTTAAAAGACGAGCCTTTATATATGCA
AGGAGTTATCATCATCGGCTTGGCAAGATGTATCGCAATGGTGGTGGTATGGAGCGATTTAGCAAAAGGTGATAGAGAAT
ACACCAGTGCTTTAGTAGCGATGAATAGCATTTTTCAAATTTTATTTTTTTCCACTTTGGCTTATATTTATCTGGATTTT
TTACCAAAATTACTAGGTCAAAGCACTTTAGCTACAAGTTTAGATATAGATTTTTCAGCTCTAAGTAAAAATGTTTTGAT
TTATTTAGGAATTCCTTTTTTAATGGGCTTTATAACAAGAACCCTACTTTTAAAATACAAAAGCAAACGATGGTACGAAA
ATACCTTTTTACCTAAAATCAGCCCTATAACTCTTATCACCCTGCTAGCAACTATTATCATTATGTGTTCTTACAAAGCA
AATGAAGTATTTCACCTGCCTTTAGAAGCTTTAAAAATAGCCTTTGTTTTGACTTTGTATTTTATCTTCATGTTTTTTCT
AACTTGGTTTATTTCTAAGAAAAATCATCTTTCTTATCCTAAAACTTGTTCTTTATGCTTTAGTGCTAGTGGAAATAACT
TTGAATTAGCTATAATCATTTGCATTGCTACTTTTGGGCTTCACTCAGAACAAGCTTTTGCAAGCATTATAGGCCCCTTA
GTAGAAGTTCCTGTACTTATCTTACTTGTAAAATGGGCATTAGGCAAAAGTTTAAATTCTAAAAAAATGAATCAAGCCTC
ATGA

Upstream 100 bases:

>100_bases
GAAGTTATGATGATGAATTTAGGAAAATAATTCAAATTTTAGATTATAAAATAACAGCTCTTTTACAAGCCATAAAGACA
AATTCTCTTAAGGACTTTAC

Downstream 100 bases:

>100_bases
TTCTTTACAAAACTTATCGCAAGGTTGATAGTCCTTGCTTTCTGGATTAAACCCATCGACTTCATTTGCAAGCATTTCTT
CATAAATTTTTATCTTTTTG

Product: arsenical-resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MLGFIDRFLTLWIFLAIFLGLILGIIFPNIALFWNLFEYKSVNVVLTLCLILMMYPPLAKVDYAKLSKVFDSKKVILLSM
ILNWFIGPLLMFILAFIFLKDEPLYMQGVIIIGLARCIAMVVVWSDLAKGDREYTSALVAMNSIFQILFFSTLAYIYLDF
LPKLLGQSTLATSLDIDFSALSKNVLIYLGIPFLMGFITRTLLLKYKSKRWYENTFLPKISPITLITLLATIIIMCSYKA
NEVFHLPLEALKIAFVLTLYFIFMFFLTWFISKKNHLSYPKTCSLCFSASGNNFELAIIICIATFGLHSEQAFASIIGPL
VEVPVLILLVKWALGKSLNSKKMNQAS

Sequences:

>Translated_347_residues
MLGFIDRFLTLWIFLAIFLGLILGIIFPNIALFWNLFEYKSVNVVLTLCLILMMYPPLAKVDYAKLSKVFDSKKVILLSM
ILNWFIGPLLMFILAFIFLKDEPLYMQGVIIIGLARCIAMVVVWSDLAKGDREYTSALVAMNSIFQILFFSTLAYIYLDF
LPKLLGQSTLATSLDIDFSALSKNVLIYLGIPFLMGFITRTLLLKYKSKRWYENTFLPKISPITLITLLATIIIMCSYKA
NEVFHLPLEALKIAFVLTLYFIFMFFLTWFISKKNHLSYPKTCSLCFSASGNNFELAIIICIATFGLHSEQAFASIIGPL
VEVPVLILLVKWALGKSLNSKKMNQAS
>Mature_347_residues
MLGFIDRFLTLWIFLAIFLGLILGIIFPNIALFWNLFEYKSVNVVLTLCLILMMYPPLAKVDYAKLSKVFDSKKVILLSM
ILNWFIGPLLMFILAFIFLKDEPLYMQGVIIIGLARCIAMVVVWSDLAKGDREYTSALVAMNSIFQILFFSTLAYIYLDF
LPKLLGQSTLATSLDIDFSALSKNVLIYLGIPFLMGFITRTLLLKYKSKRWYENTFLPKISPITLITLLATIIIMCSYKA
NEVFHLPLEALKIAFVLTLYFIFMFFLTWFISKKNHLSYPKTCSLCFSASGNNFELAIIICIATFGLHSEQAFASIIGPL
VEVPVLILLVKWALGKSLNSKKMNQAS

Specific function: Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump [H]

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=320, Percent_Identity=34.0625, Blast_Score=150, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 39436; Mature: 39436

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]