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The map label for this gene is arsC [H]

Identifier: 57238575

GI number: 57238575

Start: 1631208

End: 1631630

Strand: Direct

Name: arsC [H]

Synonym: CJE1732

Alternate gene names: 57238575

Gene position: 1631208-1631630 (Clockwise)

Preceding gene: 57238574

Following gene: 57238576

Centisome position: 91.75

GC content: 33.33

Gene sequence:

>423_bases
ATGAAACTTGCATTTATTTGTATTCACAATAGCTGCCGTTCTCAAATGGCAGAAGCACTAGCTAGGCATAAAGCTGAAAA
AATGGGCATAGATATCGAAGTATTTTCCGCAGGAAGCGACACTTCTAAGGGTGTAAATTCACAGGCTATAAGACTTATGC
GTGAAATTTATCAAATCGATATGAAAAAGCATTATTCTAAACTCATTGATTCTTTGCCTCAAAATTTAGACATAGTCGTA
AGTATGGGTTGTGGCGTGGCTTGTCCTAGCTTAAAATCAAGGTATTATTTTGATTTTGGATTAAAAGATCCTAGCGGAAG
TTATGATGATGAATTTAGGAAAATAATTCAAATTTTAGATTATAAAATAACAGCTCTTTTACAAGCCATAAAGACAAATT
CTCTTAAGGACTTTACATGTTAG

Upstream 100 bases:

>100_bases
ACAATGAGCTTTTAAAACTGCATTCTGACCTTTTTGAAAATATTAAAAATCTAGATATTGACAACATAGTTTTAGAACAA
AACACTTGCGAGAACGATAA

Downstream 100 bases:

>100_bases
GTTTTATCGATAGATTTCTCACGCTTTGGATATTTTTAGCTATTTTTTTGGGTTTAATTTTAGGTATCATTTTCCCCAAT
ATCGCTTTATTTTGGAATTT

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MKLAFICIHNSCRSQMAEALARHKAEKMGIDIEVFSAGSDTSKGVNSQAIRLMREIYQIDMKKHYSKLIDSLPQNLDIVV
SMGCGVACPSLKSRYYFDFGLKDPSGSYDDEFRKIIQILDYKITALLQAIKTNSLKDFTC

Sequences:

>Translated_140_residues
MKLAFICIHNSCRSQMAEALARHKAEKMGIDIEVFSAGSDTSKGVNSQAIRLMREIYQIDMKKHYSKLIDSLPQNLDIVV
SMGCGVACPSLKSRYYFDFGLKDPSGSYDDEFRKIIQILDYKITALLQAIKTNSLKDFTC
>Mature_140_residues
MKLAFICIHNSCRSQMAEALARHKAEKMGIDIEVFSAGSDTSKGVNSQAIRLMREIYQIDMKKHYSKLIDSLPQNLDIVV
SMGCGVACPSLKSRYYFDFGLKDPSGSYDDEFRKIIQILDYKITALLQAIKTNSLKDFTC

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 15798; Mature: 15798

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLAFICIHNSCRSQMAEALARHKAEKMGIDIEVFSAGSDTSKGVNSQAIRLMREIYQID
CEEEEEEECHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHH
MKKHYSKLIDSLPQNLDIVVSMGCGVACPSLKSRYYFDFGLKDPSGSYDDEFRKIIQILD
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
YKITALLQAIKTNSLKDFTC
HHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKLAFICIHNSCRSQMAEALARHKAEKMGIDIEVFSAGSDTSKGVNSQAIRLMREIYQID
CEEEEEEECHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHH
MKKHYSKLIDSLPQNLDIVVSMGCGVACPSLKSRYYFDFGLKDPSGSYDDEFRKIIQILD
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
YKITALLQAIKTNSLKDFTC
HHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1534327 [H]