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The map label for this gene is addA [H]

Identifier: 57238504

GI number: 57238504

Start: 1554463

End: 1557228

Strand: Reverse

Name: addA [H]

Synonym: CJE1654

Alternate gene names: 57238504

Gene position: 1557228-1554463 (Counterclockwise)

Preceding gene: 57238505

Following gene: 57238503

Centisome position: 87.59

GC content: 26.75

Gene sequence:

>2766_bases
ATGAGTCAATTTGAGCCTTTTTTGGCATTAGAAGCGAGTGCAGGAAGCGGAAAAACCTTTGCCCTGAGTGTGCGTTTTGT
AGCACTTATTTTAAAAGGAGCTAGGATTAATGAAATTTTAGCTTTGACTTTTACCAAAAAAGCTGCTAATGAAATGCAAA
AAAGAATTATTGAGACTTTTTTAAACTTAGAAAAAGAAAATAAAACCAGTGAATGCAATGAACTTTGCAAGCTTTTAGGT
AAAGATAAAGAAGAGCTTATTTCTTTAAGAGATGCTAAAAAAGAAGAATTTTTAAGAACAGAGTTAAAAATCAGTACTTT
TGATGCTTTTTTCGGAAAAATTTTGCGTGTTTTTGCTTTAAATTTGGGCTTAAGTAGTGATTTTACAATGAGTGAAGAGA
GGCTTGATGTAAGAGAGATTTTTTTAAAACTTCTTAAAAAAGATGAATTAAAAGATTTGGCTTATTATATTAATTTAGTT
GATGAGAAAGAAAATTTTTTTAACGAGCTTGAAAAATTTTATGAGAATGCTTATTTTCAAAATCGTCCTAAAATTCTAAA
TCCAACTAAAGCTTATATCAATAAAGCTTATAGTGAGTTAAGAAGTTATTGTTTGGGTCTTACTCATGTAAAAAATTATA
AAAATTTGTGTGACAATTTCAAAAGTGAAGTTTTAGATTTATCCGTGTTTATGCAATCAAGTTTTATGACAAAATTTGAA
AGTACAAAATATTTACAAGATTTAGAAAGTACTAACTTGCATTTTAGTGCAAAAAGAATGGAGTTTATAAATGCTTTAAA
TACCTATGCCATAGAGCTTGAAAATTATAAAATTGCTAATTTAATGAATCTTTTAAATCATTATAGTGAAGCTAAAAATA
TATTTCATAAAGATAAAAATACCTTAAATTTCCAAGATGTGAGTAAAAAAGTTTATGAGTTAATAACCAGTGAATTTAAG
GATATGATTTATTTTCGTTTAGATGGTTTTATTTCGCATTTGCTTATTGATGAATTTCAAGATACAAGCGTGATCCAATA
TCAAATTTTACGCCCTTTGATCGCTGAGCTTGTTTCAGGAGAAGGGGTTAAGAAAAATCGCACTTTTTTTTATGTAGGAG
ATAAAAAACAAAGTATTTATCGCTTTCGTAAAGGAAAAAAAGAATTATTTGATTTGTTAAAACAAGAATTTAGTCAAATT
AAAAGTGATAATTTAAATACTAATTATCGTTCTAAAGAGCTTTTGGTTGATTTTGTTAATGAAACTTTTAAAGAAAAAAT
CAAAGATTATAAAGAACAATTTGCCTTAGAAAGTAAAAAAGGCGGTTTTGTGCGTATTGTGGAGTCTAAGGAACAAAAGG
TTAAAAACCAAGCCCAAGAAATTAAGGAAAAGACTTTAGAAACTTTATTTGAGCAAATTAATTTTTTAAGATCTAAAAAT
ATTTCTTATGATGATATTTGTATTTTGTGTTGGAAAAATAGCGATGCAGATATGGTTTTGGATTTTTTAAGAGAGCAAAA
TATTCCTGCATTTACTCAAAGTAATGTTTTGCTTGAAAATAAAGCAAGTGTAAGACTTGTTTTAGAATATGCTAAATATT
GTATTTTTGGTGATGAGTTTTACTTGGTATTTTTAAAGGAACTTTTAGGTTTTGAGCCCAGAAAAATTACCCTTGATTTT
TCAAAAAATGCTATGGAAAATGTACTTTTTTTAATAAAAGAATTAAAACTTGATTTAAATGATATCGCTTTAATACAATT
TATCGAATATGCTAAAACTAAGGAGAATTTTTTAAAGCTTTTATTTGAGCCTTGTGCTTTGAAAATAGTAAGCGAACAAA
ATATGGGAATTAGTATTATGAGTGTGCATAAATCTAAGGGTTTGGAATTTGATCATGTGATTTTACTTGATAGTTTATCT
AAAAACAATTCAAACAATGAAGATATCATGCTTGAATATGATATCAATCAAGGTTGGCAACTCCATATTAAAGATAAAAT
TCGAGAGCTTACTAAAGAGCCTATTTATACTCTTTTTAAAGAAAATATTACAAGAGCAAATTATGAAGATGATATTAATA
AACTTTATGTGGCTTTTACAAGAGCTAAGGAAAGTTTGATCATCATAAAAAGAAATGAAGAAAGTGTAAATGGAAATTAT
CCAAGTTATTTTAAGGGGGGATTTTTAAATATACATTCTCAAGAGAGAGGTTTTTTAGAAAGCAAAGAACAAATTTTAAG
CGTTAAAAAAGAAAGCATTCAAACTTTGCAAAAATTTGAAAAAATTACCTTGCAAGAAATTCAAAGCGAAGAAAGGCTTG
ATAGTAAAGAACTATATTTTGGAAATGCTTTTCACTTTTTTATGCAAAATTTAAAACTTCCTAAGGGTGAAAATTTTCAA
ATACTTACTCAAAGATGCAAGAGTAAATTTAGACATTTTTTAGATGAGAGTGATTTTGAAAAGCTTTTTAAAAGAATTGA
AATTTTACTTAAAAATATTCAATTTCAAAATTTGATTGGTGATGGAAAGCTTTTAAAAGAACAAGCTTTGAGTTTTAATG
GAGAAATTAAACAATTAGACTTGCTTGCTTTAAAAGATGAAGAAGCTTTTATAATTGATTATAAAACAGGTCTTGCTATG
CAAGATAAACATAAAGAGCAGGTAGGAACTTATAAGATCGCCATTAGTGAAATTTTGCAAAAAGATAAAGTGCGTGCTTT
TATAGTTTATTGTTTGGAAAATGAAATTCAAATTTTGGAAATATAA

Upstream 100 bases:

>100_bases
GACTTAAAGATTTAGTTCTTATGAGTAAGGAAGAAATAGAGTTTGAAAATGAACAAGATGAGTATTGTCCTTATAAACTC
ATTTATAAAAAGGAATTAAA

Downstream 100 bases:

>100_bases
ACTTTATTTTTACTTAAATTAAGTAAAAATTAATATTATTTTTTATACAATCACATTTTAAATTTTTGGCAAAGGTAAAA
ATTATGACAAAGATAACAAA

Product: recombination protein RecB

Products: NA

Alternate protein names: ATP-dependent helicase/nuclease AddA [H]

Number of amino acids: Translated: 921; Mature: 920

Protein sequence:

>921_residues
MSQFEPFLALEASAGSGKTFALSVRFVALILKGARINEILALTFTKKAANEMQKRIIETFLNLEKENKTSECNELCKLLG
KDKEELISLRDAKKEEFLRTELKISTFDAFFGKILRVFALNLGLSSDFTMSEERLDVREIFLKLLKKDELKDLAYYINLV
DEKENFFNELEKFYENAYFQNRPKILNPTKAYINKAYSELRSYCLGLTHVKNYKNLCDNFKSEVLDLSVFMQSSFMTKFE
STKYLQDLESTNLHFSAKRMEFINALNTYAIELENYKIANLMNLLNHYSEAKNIFHKDKNTLNFQDVSKKVYELITSEFK
DMIYFRLDGFISHLLIDEFQDTSVIQYQILRPLIAELVSGEGVKKNRTFFYVGDKKQSIYRFRKGKKELFDLLKQEFSQI
KSDNLNTNYRSKELLVDFVNETFKEKIKDYKEQFALESKKGGFVRIVESKEQKVKNQAQEIKEKTLETLFEQINFLRSKN
ISYDDICILCWKNSDADMVLDFLREQNIPAFTQSNVLLENKASVRLVLEYAKYCIFGDEFYLVFLKELLGFEPRKITLDF
SKNAMENVLFLIKELKLDLNDIALIQFIEYAKTKENFLKLLFEPCALKIVSEQNMGISIMSVHKSKGLEFDHVILLDSLS
KNNSNNEDIMLEYDINQGWQLHIKDKIRELTKEPIYTLFKENITRANYEDDINKLYVAFTRAKESLIIIKRNEESVNGNY
PSYFKGGFLNIHSQERGFLESKEQILSVKKESIQTLQKFEKITLQEIQSEERLDSKELYFGNAFHFFMQNLKLPKGENFQ
ILTQRCKSKFRHFLDESDFEKLFKRIEILLKNIQFQNLIGDGKLLKEQALSFNGEIKQLDLLALKDEEAFIIDYKTGLAM
QDKHKEQVGTYKIAISEILQKDKVRAFIVYCLENEIQILEI

Sequences:

>Translated_921_residues
MSQFEPFLALEASAGSGKTFALSVRFVALILKGARINEILALTFTKKAANEMQKRIIETFLNLEKENKTSECNELCKLLG
KDKEELISLRDAKKEEFLRTELKISTFDAFFGKILRVFALNLGLSSDFTMSEERLDVREIFLKLLKKDELKDLAYYINLV
DEKENFFNELEKFYENAYFQNRPKILNPTKAYINKAYSELRSYCLGLTHVKNYKNLCDNFKSEVLDLSVFMQSSFMTKFE
STKYLQDLESTNLHFSAKRMEFINALNTYAIELENYKIANLMNLLNHYSEAKNIFHKDKNTLNFQDVSKKVYELITSEFK
DMIYFRLDGFISHLLIDEFQDTSVIQYQILRPLIAELVSGEGVKKNRTFFYVGDKKQSIYRFRKGKKELFDLLKQEFSQI
KSDNLNTNYRSKELLVDFVNETFKEKIKDYKEQFALESKKGGFVRIVESKEQKVKNQAQEIKEKTLETLFEQINFLRSKN
ISYDDICILCWKNSDADMVLDFLREQNIPAFTQSNVLLENKASVRLVLEYAKYCIFGDEFYLVFLKELLGFEPRKITLDF
SKNAMENVLFLIKELKLDLNDIALIQFIEYAKTKENFLKLLFEPCALKIVSEQNMGISIMSVHKSKGLEFDHVILLDSLS
KNNSNNEDIMLEYDINQGWQLHIKDKIRELTKEPIYTLFKENITRANYEDDINKLYVAFTRAKESLIIIKRNEESVNGNY
PSYFKGGFLNIHSQERGFLESKEQILSVKKESIQTLQKFEKITLQEIQSEERLDSKELYFGNAFHFFMQNLKLPKGENFQ
ILTQRCKSKFRHFLDESDFEKLFKRIEILLKNIQFQNLIGDGKLLKEQALSFNGEIKQLDLLALKDEEAFIIDYKTGLAM
QDKHKEQVGTYKIAISEILQKDKVRAFIVYCLENEIQILEI
>Mature_920_residues
SQFEPFLALEASAGSGKTFALSVRFVALILKGARINEILALTFTKKAANEMQKRIIETFLNLEKENKTSECNELCKLLGK
DKEELISLRDAKKEEFLRTELKISTFDAFFGKILRVFALNLGLSSDFTMSEERLDVREIFLKLLKKDELKDLAYYINLVD
EKENFFNELEKFYENAYFQNRPKILNPTKAYINKAYSELRSYCLGLTHVKNYKNLCDNFKSEVLDLSVFMQSSFMTKFES
TKYLQDLESTNLHFSAKRMEFINALNTYAIELENYKIANLMNLLNHYSEAKNIFHKDKNTLNFQDVSKKVYELITSEFKD
MIYFRLDGFISHLLIDEFQDTSVIQYQILRPLIAELVSGEGVKKNRTFFYVGDKKQSIYRFRKGKKELFDLLKQEFSQIK
SDNLNTNYRSKELLVDFVNETFKEKIKDYKEQFALESKKGGFVRIVESKEQKVKNQAQEIKEKTLETLFEQINFLRSKNI
SYDDICILCWKNSDADMVLDFLREQNIPAFTQSNVLLENKASVRLVLEYAKYCIFGDEFYLVFLKELLGFEPRKITLDFS
KNAMENVLFLIKELKLDLNDIALIQFIEYAKTKENFLKLLFEPCALKIVSEQNMGISIMSVHKSKGLEFDHVILLDSLSK
NNSNNEDIMLEYDINQGWQLHIKDKIRELTKEPIYTLFKENITRANYEDDINKLYVAFTRAKESLIIIKRNEESVNGNYP
SYFKGGFLNIHSQERGFLESKEQILSVKKESIQTLQKFEKITLQEIQSEERLDSKELYFGNAFHFFMQNLKLPKGENFQI
LTQRCKSKFRHFLDESDFEKLFKRIEILLKNIQFQNLIGDGKLLKEQALSFNGEIKQLDLLALKDEEAFIIDYKTGLAMQ
DKHKEQVGTYKIAISEILQKDKVRAFIVYCLENEIQILEI

Specific function: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domai

COG id: COG1074

COG function: function code L; ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014152
- InterPro:   IPR014017
- InterPro:   IPR000212
- InterPro:   IPR011604
- InterPro:   IPR014016
- InterPro:   IPR011335 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 108145; Mature: 108014

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQFEPFLALEASAGSGKTFALSVRFVALILKGARINEILALTFTKKAANEMQKRIIETF
CCCCCCCEEEEECCCCCCEEEHHHHHHHHHHCCCCHHHEEEEEECHHHHHHHHHHHHHHH
LNLEKENKTSECNELCKLLGKDKEELISLRDAKKEEFLRTELKISTFDAFFGKILRVFAL
HCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLGLSSDFTMSEERLDVREIFLKLLKKDELKDLAYYINLVDEKENFFNELEKFYENAYFQ
HCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NRPKILNPTKAYINKAYSELRSYCLGLTHVKNYKNLCDNFKSEVLDLSVFMQSSFMTKFE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STKYLQDLESTNLHFSAKRMEFINALNTYAIELENYKIANLMNLLNHYSEAKNIFHKDKN
HHHHHHHHHCCCCEEHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCC
TLNFQDVSKKVYELITSEFKDMIYFRLDGFISHLLIDEFQDTSVIQYQILRPLIAELVSG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
EGVKKNRTFFYVGDKKQSIYRFRKGKKELFDLLKQEFSQIKSDNLNTNYRSKELLVDFVN
CCCCCCCEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
ETFKEKIKDYKEQFALESKKGGFVRIVESKEQKVKNQAQEIKEKTLETLFEQINFLRSKN
HHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ISYDDICILCWKNSDADMVLDFLREQNIPAFTQSNVLLENKASVRLVLEYAKYCIFGDEF
CCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCHH
YLVFLKELLGFEPRKITLDFSKNAMENVLFLIKELKLDLNDIALIQFIEYAKTKENFLKL
HHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LFEPCALKIVSEQNMGISIMSVHKSKGLEFDHVILLDSLSKNNSNNEDIMLEYDINQGWQ
HHHHHHHEEEECCCCCEEEEEEHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCE
LHIKDKIRELTKEPIYTLFKENITRANYEDDINKLYVAFTRAKESLIIIKRNEESVNGNY
EEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEECCCEEEEEECCCCCCCCCC
PSYFKGGFLNIHSQERGFLESKEQILSVKKESIQTLQKFEKITLQEIQSEERLDSKELYF
CCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
GNAFHFFMQNLKLPKGENFQILTQRCKSKFRHFLDESDFEKLFKRIEILLKNIQFQNLIG
CHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
DGKLLKEQALSFNGEIKQLDLLALKDEEAFIIDYKTGLAMQDKHKEQVGTYKIAISEILQ
CCHHHHHHHHCCCCCCEEEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
KDKVRAFIVYCLENEIQILEI
HCCHHEEEEEEECCCEEEEEC
>Mature Secondary Structure 
SQFEPFLALEASAGSGKTFALSVRFVALILKGARINEILALTFTKKAANEMQKRIIETF
CCCCCCEEEEECCCCCCEEEHHHHHHHHHHCCCCHHHEEEEEECHHHHHHHHHHHHHHH
LNLEKENKTSECNELCKLLGKDKEELISLRDAKKEEFLRTELKISTFDAFFGKILRVFAL
HCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLGLSSDFTMSEERLDVREIFLKLLKKDELKDLAYYINLVDEKENFFNELEKFYENAYFQ
HCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NRPKILNPTKAYINKAYSELRSYCLGLTHVKNYKNLCDNFKSEVLDLSVFMQSSFMTKFE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STKYLQDLESTNLHFSAKRMEFINALNTYAIELENYKIANLMNLLNHYSEAKNIFHKDKN
HHHHHHHHHCCCCEEHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCC
TLNFQDVSKKVYELITSEFKDMIYFRLDGFISHLLIDEFQDTSVIQYQILRPLIAELVSG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
EGVKKNRTFFYVGDKKQSIYRFRKGKKELFDLLKQEFSQIKSDNLNTNYRSKELLVDFVN
CCCCCCCEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
ETFKEKIKDYKEQFALESKKGGFVRIVESKEQKVKNQAQEIKEKTLETLFEQINFLRSKN
HHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ISYDDICILCWKNSDADMVLDFLREQNIPAFTQSNVLLENKASVRLVLEYAKYCIFGDEF
CCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCHH
YLVFLKELLGFEPRKITLDFSKNAMENVLFLIKELKLDLNDIALIQFIEYAKTKENFLKL
HHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LFEPCALKIVSEQNMGISIMSVHKSKGLEFDHVILLDSLSKNNSNNEDIMLEYDINQGWQ
HHHHHHHEEEECCCCCEEEEEEHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCE
LHIKDKIRELTKEPIYTLFKENITRANYEDDINKLYVAFTRAKESLIIIKRNEESVNGNY
EEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEECCCEEEEEECCCCCCCCCC
PSYFKGGFLNIHSQERGFLESKEQILSVKKESIQTLQKFEKITLQEIQSEERLDSKELYF
CCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
GNAFHFFMQNLKLPKGENFQILTQRCKSKFRHFLDESDFEKLFKRIEILLKNIQFQNLIG
CHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
DGKLLKEQALSFNGEIKQLDLLALKDEEAFIIDYKTGLAMQDKHKEQVGTYKIAISEILQ
CCHHHHHHHHCCCCCCEEEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
KDKVRAFIVYCLENEIQILEI
HCCHHEEEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA