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The map label for this gene is yliG [H]

Identifier: 57238477

GI number: 57238477

Start: 1529772

End: 1531091

Strand: Reverse

Name: yliG [H]

Synonym: CJE1627

Alternate gene names: 57238477

Gene position: 1531091-1529772 (Counterclockwise)

Preceding gene: 57238479

Following gene: 57238476

Centisome position: 86.12

GC content: 34.47

Gene sequence:

>1320_bases
ATGTCAAAACTTTATCTTATGTCTTTAGGTTGTAATAAAAATTTAGTCGATAGTGAGATCATGCTAGGGCGCCTTAGCGC
TTATGAACTTTGCGATGAACCAAGCAAAGCTGATGTTATAATCGTAAATACTTGTGGTTTTATCGATAGTGCAAAAAAAG
AAAGTATTAATGCGATTTTGGATTTGCACGAACAAAGAAAAAAAGATTCTCTTTTGGTGGTTACGGGTTGTTTGATGCAG
CGTTACCGCGAAGAACTTATGAAAGAACTTCCTGAGGTTGATCTTTTCACAGGTGTGGGTGATTATGAAAGAGTCGATGA
AATGATACTTAAAAAAACAAATTTATTTTCAAATTCGACTTATTTGCAGAGTGAAAATTCTAAACGTATTATCACAGGTT
CAAATTCCCATGCTTTTATAAAAATCGCCGAAGGTTGTAATCAAAAATGCTCTTTTTGTGCCATCCCAAGTTTTAAAGGC
AAGTTAAAATCTCGCGAGATAAGTAGCATTATAGCTGAGCTTAAAGATTTGGTAGCTAGAGGTTATAAGGACTTTTCTTT
TATTGCACAAGATACGAGTTCTTATTTGTTTGATAAGGGTGAAAAAGATGGGCTTATACGCTTAATCGATGAGGTGGAAA
AAATCAAAGGCATAAGAGCGGCTAGAATTTTATATCTTTATCCTACGAGTGCGAGTGAAGCTTTGATCAAACGCATTATA
GCTTCTGAAATTTTTGTAAATTATTTTGATATGCCTTTACAGCACATAAGTGATAATATGCTTAAAATCATGAAGCGTGG
GGCAAATAGCACAAGACTTAAAGAAATGCTAAATTTAATGAAAAGTGCGCCAAATAGCTTTTTACGCACGGGCTTTATCG
TAGGGCATCCAGGTGAAAGTGAGGCAGATTTTGAAGAGCTTTGTGAGTTTGTTAAAGACTTTGGTTTTGATAGAGTGAGT
GTTTTTGCGTATTCTAAGGAAGAAGATACAGCCGCTTTTGATATGGAGCAAGTGTCTTTTAAAGTGATCAATAAAAGGCT
TAAAATCATAGAAAAAATTGTTAATGAAGTGATAGAAAAAAGTTTTGAAAAAGAAGTGGGGCAAAAGCGTTTAGTAGTTT
GCACAGGAGAAAGTAGTGAGGGAGAGTTTTTCATCGCAGCTAAAGATTTAAGATGGGATAGAGAGATTGATGGGGAAATT
CTTATCAATGAAAGCGAATGTGGAAATTTAGAAATGGGGCAAATTTATGAATGTGAAATTTTACAAAACCTTGATAAAAA
GCTCCTTGCTAAGGCTTTAAGAAAAGTAGATGCAAATTAA

Upstream 100 bases:

>100_bases
AAGTTCGCTAAATTCGTAATTATCCATAAAATTTCTTTGCTATAATTATATTTTTAAAGTCAAAAATTATATCAAAAGAA
AACTTTAATATAGGAAAAAA

Downstream 100 bases:

>100_bases
AGATGAAATTTTAGCCCTTTTAAAAAAGGGTAAAAATTTACTCGCTTTTTCTTATGGAAGTGATTCTAGTGCGCTTTTTT
ATCTTTTAATGCAAGAAAAG

Product: tRNA modifying protein

Products: NA

Alternate protein names: S12 MTTase; S12 methylthiotransferase; Ribosome maturation factor RimO [H]

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MSKLYLMSLGCNKNLVDSEIMLGRLSAYELCDEPSKADVIIVNTCGFIDSAKKESINAILDLHEQRKKDSLLVVTGCLMQ
RYREELMKELPEVDLFTGVGDYERVDEMILKKTNLFSNSTYLQSENSKRIITGSNSHAFIKIAEGCNQKCSFCAIPSFKG
KLKSREISSIIAELKDLVARGYKDFSFIAQDTSSYLFDKGEKDGLIRLIDEVEKIKGIRAARILYLYPTSASEALIKRII
ASEIFVNYFDMPLQHISDNMLKIMKRGANSTRLKEMLNLMKSAPNSFLRTGFIVGHPGESEADFEELCEFVKDFGFDRVS
VFAYSKEEDTAAFDMEQVSFKVINKRLKIIEKIVNEVIEKSFEKEVGQKRLVVCTGESSEGEFFIAAKDLRWDREIDGEI
LINESECGNLEMGQIYECEILQNLDKKLLAKALRKVDAN

Sequences:

>Translated_439_residues
MSKLYLMSLGCNKNLVDSEIMLGRLSAYELCDEPSKADVIIVNTCGFIDSAKKESINAILDLHEQRKKDSLLVVTGCLMQ
RYREELMKELPEVDLFTGVGDYERVDEMILKKTNLFSNSTYLQSENSKRIITGSNSHAFIKIAEGCNQKCSFCAIPSFKG
KLKSREISSIIAELKDLVARGYKDFSFIAQDTSSYLFDKGEKDGLIRLIDEVEKIKGIRAARILYLYPTSASEALIKRII
ASEIFVNYFDMPLQHISDNMLKIMKRGANSTRLKEMLNLMKSAPNSFLRTGFIVGHPGESEADFEELCEFVKDFGFDRVS
VFAYSKEEDTAAFDMEQVSFKVINKRLKIIEKIVNEVIEKSFEKEVGQKRLVVCTGESSEGEFFIAAKDLRWDREIDGEI
LINESECGNLEMGQIYECEILQNLDKKLLAKALRKVDAN
>Mature_438_residues
SKLYLMSLGCNKNLVDSEIMLGRLSAYELCDEPSKADVIIVNTCGFIDSAKKESINAILDLHEQRKKDSLLVVTGCLMQR
YREELMKELPEVDLFTGVGDYERVDEMILKKTNLFSNSTYLQSENSKRIITGSNSHAFIKIAEGCNQKCSFCAIPSFKGK
LKSREISSIIAELKDLVARGYKDFSFIAQDTSSYLFDKGEKDGLIRLIDEVEKIKGIRAARILYLYPTSASEALIKRIIA
SEIFVNYFDMPLQHISDNMLKIMKRGANSTRLKEMLNLMKSAPNSFLRTGFIVGHPGESEADFEELCEFVKDFGFDRVSV
FAYSKEEDTAAFDMEQVSFKVINKRLKIIEKIVNEVIEKSFEKEVGQKRLVVCTGESSEGEFFIAAKDLRWDREIDGEIL
INESECGNLEMGQIYECEILQNLDKKLLAKALRKVDAN

Specific function: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 [H]

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=402, Percent_Identity=24.6268656716418, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI28872784, Length=416, Percent_Identity=24.7596153846154, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI28872782, Length=416, Percent_Identity=24.7596153846154, Blast_Score=125, Evalue=8e-29,
Organism=Escherichia coli, GI1787057, Length=417, Percent_Identity=34.7721822541966, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1786882, Length=396, Percent_Identity=26.7676767676768, Blast_Score=146, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17553146, Length=451, Percent_Identity=22.1729490022173, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21356207, Length=428, Percent_Identity=25, Blast_Score=134, Evalue=9e-32,
Organism=Drosophila melanogaster, GI19922432, Length=369, Percent_Identity=23.5772357723577, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR007197
- InterPro:   IPR005840 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 49828; Mature: 49697

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLYLMSLGCNKNLVDSEIMLGRLSAYELCDEPSKADVIIVNTCGFIDSAKKESINAIL
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHH
DLHEQRKKDSLLVVTGCLMQRYREELMKELPEVDLFTGVGDYERVDEMILKKTNLFSNST
HHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCCCCCC
YLQSENSKRIITGSNSHAFIKIAEGCNQKCSFCAIPSFKGKLKSREISSIIAELKDLVAR
EEECCCCCEEEECCCCCEEEEECCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHC
GYKDFSFIAQDTSSYLFDKGEKDGLIRLIDEVEKIKGIRAARILYLYPTSASEALIKRII
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHH
ASEIFVNYFDMPLQHISDNMLKIMKRGANSTRLKEMLNLMKSAPNSFLRTGFIVGHPGES
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHCCEEEECCCCC
EADFEELCEFVKDFGFDRVSVFAYSKEEDTAAFDMEQVSFKVINKRLKIIEKIVNEVIEK
CCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFEKEVGQKRLVVCTGESSEGEFFIAAKDLRWDREIDGEILINESECGNLEMGQIYECEI
HHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCEEHHHH
LQNLDKKLLAKALRKVDAN
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKLYLMSLGCNKNLVDSEIMLGRLSAYELCDEPSKADVIIVNTCGFIDSAKKESINAIL
CCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHH
DLHEQRKKDSLLVVTGCLMQRYREELMKELPEVDLFTGVGDYERVDEMILKKTNLFSNST
HHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCCCCCC
YLQSENSKRIITGSNSHAFIKIAEGCNQKCSFCAIPSFKGKLKSREISSIIAELKDLVAR
EEECCCCCEEEECCCCCEEEEECCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHC
GYKDFSFIAQDTSSYLFDKGEKDGLIRLIDEVEKIKGIRAARILYLYPTSASEALIKRII
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHH
ASEIFVNYFDMPLQHISDNMLKIMKRGANSTRLKEMLNLMKSAPNSFLRTGFIVGHPGES
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHCCEEEECCCCC
EADFEELCEFVKDFGFDRVSVFAYSKEEDTAAFDMEQVSFKVINKRLKIIEKIVNEVIEK
CCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFEKEVGQKRLVVCTGESSEGEFFIAAKDLRWDREIDGEILINESECGNLEMGQIYECEI
HHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCEEHHHH
LQNLDKKLLAKALRKVDAN
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA