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The map label for this gene is kpsD [H]

Identifier: 57238468

GI number: 57238468

Start: 1522058

End: 1523716

Strand: Reverse

Name: kpsD [H]

Synonym: CJE1618

Alternate gene names: 57238468

Gene position: 1523716-1522058 (Counterclockwise)

Preceding gene: 57238469

Following gene: 57238467

Centisome position: 85.71

GC content: 31.4

Gene sequence:

>1659_bases
ATGAAAAAAATATTAATTTTACTTTTTAGTTGTATTTTATGTTTTGGAGCTGTGGATGTTTCACAAATCATTTCAGCAGA
GGATCAAGGTTCTACTACAACTAGCATAGATCAAAATTTAAGCTCAAATTATGATATAGCAAATAAAGAAAATAATCTTA
CAAAAATTCATCAAATTTTAGTATTCGGTGCTCATCTTTTTAATGGAAATTTTAAAAATTACAATCAAAGAGTTTATAAC
CCAGATTATAAGATCGCAGTTGGTGATCAAATCAGTCTTAAAATTTGGGGAGCTGTTGAGTTTTCGCAAGTTTTAGTGGT
GGATTCTCAAGGAAATATTTTTATCCCTAAAGTAGGAGCTGTAAATTTACTAGGTGTGAAAAATAGCGCCCTTGTAAGTG
TTATAAAAGCACGTGTTAATAAAATCTATAAAAGCAATGTTTTTGTTTATGCAGATATGAATGCTTATCAAAATGTCAGT
GTTTTTGTAACAGGAAGTGTTAATGCTCCAGGACTTTATCAAGGACTTAGTTCGGATTCAGTGATACAGTATCTTGATAA
AGCAGGGGGTATAAATTTAGAATATGGAAGTTTTAGAGATATTCAAATTTTGCGTAATAACAGCGTGATAAAAAATATTG
ATTTATATGATTTTTTGCTAAAAGGGCAAATGGATCTTTTTCTTTTTAGAAGCGGAGATGTTATTTTAGTAGGAAATGTT
CAAAATTACGCTTTTGTTGATGGTGATGTGCAAAGACCTTTTCGTTTTGAACTTTCAAATGATATTAAAACTTTAGCTGA
CTTAGCTAGAGTATCAGGTGCTAAACCTATTGTAACTAATGCTATCGTAAAAAGTTATGGTGAAGATCATAAACTTGATG
TCAGTGCTTATAATAAAATGCAATTTCCAAAAGTTTTACTTAGAACGGGAGATGAGGTAGAATTTCACCCTGAGTATGTT
TCTAAAAATATAACTATAAGTGTAAATGGCGAGCATAATGGTTTAAAAACTTTAGTTGTGGGTAAAGGAACGACTTTAGA
AGATATTTCTAAATTAATTAAAGCCAATCCACAATCAAACATGCAAGCTTTACAAGTGTTTAGAAAAAGTGTAGCTAGAA
CTCAAAAAGAACTTATCAATGCTCAGCTTAAAGAGCTTGAAACTCTAGCTTTAACTAGTGGTTCTGTTACAGCTCAAGGT
GCAGCTATAAGAGCTCAACAAGCAAAAACGATTTTAGAATTTATCCAAAGAGCTAAGCAAGTAGAGCCTAAGGGTCAAAT
TGTCATTGATAATCCAAAGTCTTATAATTCGGTTATTTTAGAAGATGGTGATACTATTAATGTACCAAGTAAGAATAATC
TCATCATAGTTCAAGGTGAGGTTTCTTTACCTGGAGCTTTTGTGTATGATAAGGGCAAAGATTTAAGATATTATATCAAT
CTTGCAGGAGGTTATGGAGAAAGAGCGGATACTTCAAAAGTTTTGGTGATACGAAGCAATGGAAAAGCTGAAAAATATCA
TAGTGGTATAGATATGAAACCAGGCGATTCTGTGTTGGTATTGCCAAAAGTAGATAGTGAGAATTTGCAAATTTTTTCAA
TGTTAACTCAAATTCTTTATCAAATTGCTATTGCAACCAATGTTGTGCTTAATCTTTAA

Upstream 100 bases:

>100_bases
GAAAGAATTTATGATATTTTAACAGCATTTATTGTATTATCTTTGATTTTTGGGATTGTTAAATTTATTAAAATGATAAT
AGAGGAGCATAAGTATTAAA

Downstream 100 bases:

>100_bases
GGTTTAAAAATGAATACTCTTGAAATAGCCAAAGAAGTCTTTGAAAAAGAAGCGCAAGCTATTTTGGATTTGGCTAAAAA
TTTAGATGAAAATTTTAATC

Product: capsular polysaccharide ABC transporter periplasmic polysaccharide-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MKKILILLFSCILCFGAVDVSQIISAEDQGSTTTSIDQNLSSNYDIANKENNLTKIHQILVFGAHLFNGNFKNYNQRVYN
PDYKIAVGDQISLKIWGAVEFSQVLVVDSQGNIFIPKVGAVNLLGVKNSALVSVIKARVNKIYKSNVFVYADMNAYQNVS
VFVTGSVNAPGLYQGLSSDSVIQYLDKAGGINLEYGSFRDIQILRNNSVIKNIDLYDFLLKGQMDLFLFRSGDVILVGNV
QNYAFVDGDVQRPFRFELSNDIKTLADLARVSGAKPIVTNAIVKSYGEDHKLDVSAYNKMQFPKVLLRTGDEVEFHPEYV
SKNITISVNGEHNGLKTLVVGKGTTLEDISKLIKANPQSNMQALQVFRKSVARTQKELINAQLKELETLALTSGSVTAQG
AAIRAQQAKTILEFIQRAKQVEPKGQIVIDNPKSYNSVILEDGDTINVPSKNNLIIVQGEVSLPGAFVYDKGKDLRYYIN
LAGGYGERADTSKVLVIRSNGKAEKYHSGIDMKPGDSVLVLPKVDSENLQIFSMLTQILYQIAIATNVVLNL

Sequences:

>Translated_552_residues
MKKILILLFSCILCFGAVDVSQIISAEDQGSTTTSIDQNLSSNYDIANKENNLTKIHQILVFGAHLFNGNFKNYNQRVYN
PDYKIAVGDQISLKIWGAVEFSQVLVVDSQGNIFIPKVGAVNLLGVKNSALVSVIKARVNKIYKSNVFVYADMNAYQNVS
VFVTGSVNAPGLYQGLSSDSVIQYLDKAGGINLEYGSFRDIQILRNNSVIKNIDLYDFLLKGQMDLFLFRSGDVILVGNV
QNYAFVDGDVQRPFRFELSNDIKTLADLARVSGAKPIVTNAIVKSYGEDHKLDVSAYNKMQFPKVLLRTGDEVEFHPEYV
SKNITISVNGEHNGLKTLVVGKGTTLEDISKLIKANPQSNMQALQVFRKSVARTQKELINAQLKELETLALTSGSVTAQG
AAIRAQQAKTILEFIQRAKQVEPKGQIVIDNPKSYNSVILEDGDTINVPSKNNLIIVQGEVSLPGAFVYDKGKDLRYYIN
LAGGYGERADTSKVLVIRSNGKAEKYHSGIDMKPGDSVLVLPKVDSENLQIFSMLTQILYQIAIATNVVLNL
>Mature_552_residues
MKKILILLFSCILCFGAVDVSQIISAEDQGSTTTSIDQNLSSNYDIANKENNLTKIHQILVFGAHLFNGNFKNYNQRVYN
PDYKIAVGDQISLKIWGAVEFSQVLVVDSQGNIFIPKVGAVNLLGVKNSALVSVIKARVNKIYKSNVFVYADMNAYQNVS
VFVTGSVNAPGLYQGLSSDSVIQYLDKAGGINLEYGSFRDIQILRNNSVIKNIDLYDFLLKGQMDLFLFRSGDVILVGNV
QNYAFVDGDVQRPFRFELSNDIKTLADLARVSGAKPIVTNAIVKSYGEDHKLDVSAYNKMQFPKVLLRTGDEVEFHPEYV
SKNITISVNGEHNGLKTLVVGKGTTLEDISKLIKANPQSNMQALQVFRKSVARTQKELINAQLKELETLALTSGSVTAQG
AAIRAQQAKTILEFIQRAKQVEPKGQIVIDNPKSYNSVILEDGDTINVPSKNNLIIVQGEVSLPGAFVYDKGKDLRYYIN
LAGGYGERADTSKVLVIRSNGKAEKYHSGIDMKPGDSVLVLPKVDSENLQIFSMLTQILYQIAIATNVVLNL

Specific function: Involved in the translocation of the polysialic acid capsule across the outer membrane to the cell surface. May function as the periplasmic binding element of the PSA transport system, in which it transiently interacts with the membrane component of the t

COG id: COG1596

COG function: function code M; Periplasmic protein involved in polysaccharide export

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli K5 kpsD [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003715 [H]

Pfam domain/function: PF02563 Poly_export [H]

EC number: NA

Molecular weight: Translated: 60813; Mature: 60813

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILILLFSCILCFGAVDVSQIISAEDQGSTTTSIDQNLSSNYDIANKENNLTKIHQIL
CHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHH
VFGAHLFNGNFKNYNQRVYNPDYKIAVGDQISLKIWGAVEFSQVLVVDSQGNIFIPKVGA
HHHHHHCCCCCCCCCCEEECCCEEEEECCEEEEEEEEEEEEEEEEEEECCCCEEEECCCC
VNLLGVKNSALVSVIKARVNKIYKSNVFVYADMNAYQNVSVFVTGSVNAPGLYQGLSSDS
EEEEECCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEECCCCCHHHCCCCCCH
VIQYLDKAGGINLEYGSFRDIQILRNNSVIKNIDLYDFLLKGQMDLFLFRSGDVILVGNV
HHHHHHHCCCCEEECCCCCEEEEEECCCEEECCCHHHHHHCCCEEEEEEECCCEEEEECC
QNYAFVDGDVQRPFRFELSNDIKTLADLARVSGAKPIVTNAIVKSYGEDHKLDVSAYNKM
CCEEEECCCCCCCEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEHHHHCCC
QFPKVLLRTGDEVEFHPEYVSKNITISVNGEHNGLKTLVVGKGTTLEDISKLIKANPQSN
CCCHHHHHCCCCCEECHHHHCCEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHCCCCCH
MQALQVFRKSVARTQKELINAQLKELETLALTSGSVTAQGAAIRAQQAKTILEFIQRAKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEECCCHHHHHHHHHHHHHHHHHHC
VEPKGQIVIDNPKSYNSVILEDGDTINVPSKNNLIIVQGEVSLPGAFVYDKGKDLRYYIN
CCCCCCEEEECCCCCCEEEEECCCEEECCCCCCEEEEEECCCCCEEEEEECCCCEEEEEE
LAGGYGERADTSKVLVIRSNGKAEKYHSGIDMKPGDSVLVLPKVDSENLQIFSMLTQILY
EECCCCCCCCCCEEEEEECCCCCHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHH
QIAIATNVVLNL
HHHHHHHHEEEC
>Mature Secondary Structure
MKKILILLFSCILCFGAVDVSQIISAEDQGSTTTSIDQNLSSNYDIANKENNLTKIHQIL
CHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHH
VFGAHLFNGNFKNYNQRVYNPDYKIAVGDQISLKIWGAVEFSQVLVVDSQGNIFIPKVGA
HHHHHHCCCCCCCCCCEEECCCEEEEECCEEEEEEEEEEEEEEEEEEECCCCEEEECCCC
VNLLGVKNSALVSVIKARVNKIYKSNVFVYADMNAYQNVSVFVTGSVNAPGLYQGLSSDS
EEEEECCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEECCCCCHHHCCCCCCH
VIQYLDKAGGINLEYGSFRDIQILRNNSVIKNIDLYDFLLKGQMDLFLFRSGDVILVGNV
HHHHHHHCCCCEEECCCCCEEEEEECCCEEECCCHHHHHHCCCEEEEEEECCCEEEEECC
QNYAFVDGDVQRPFRFELSNDIKTLADLARVSGAKPIVTNAIVKSYGEDHKLDVSAYNKM
CCEEEECCCCCCCEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEHHHHCCC
QFPKVLLRTGDEVEFHPEYVSKNITISVNGEHNGLKTLVVGKGTTLEDISKLIKANPQSN
CCCHHHHHCCCCCEECHHHHCCEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHCCCCCH
MQALQVFRKSVARTQKELINAQLKELETLALTSGSVTAQGAAIRAQQAKTILEFIQRAKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEECCCHHHHHHHHHHHHHHHHHHC
VEPKGQIVIDNPKSYNSVILEDGDTINVPSKNNLIIVQGEVSLPGAFVYDKGKDLRYYIN
CCCCCCEEEECCCCCCEEEEECCCEEECCCCCCEEEEEECCCCCEEEEEECCCCEEEEEE
LAGGYGERADTSKVLVIRSNGKAEKYHSGIDMKPGDSVLVLPKVDSENLQIFSMLTQILY
EECCCCCCCCCCEEEEEECCCCCHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHH
QIAIATNVVLNL
HHHHHHHHEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8021185 [H]