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The map label for this gene is selA [H]

Identifier: 57238421

GI number: 57238421

Start: 1470867

End: 1472189

Strand: Direct

Name: selA [H]

Synonym: CJE1569

Alternate gene names: 57238421

Gene position: 1470867-1472189 (Clockwise)

Preceding gene: 57238419

Following gene: 57238422

Centisome position: 82.73

GC content: 29.71

Gene sequence:

>1323_bases
ATGAACAAATTTAGAACTTTTCCACAGATTAACACTCTTATTGAAGATGAGAGTTTAAAATCCTATCCTTTTTATATCAA
AGTATTTTTTTGTAAAAAAGTTGTCGCAAAACTAAAAGAAAATTTTTCCCAAGATGAAATTTCTAAAGATAAACTACTTT
TAGAAATCAAAAAAGAAATCAAAACTTTTTACCGCAAAGATTTACAAAGTGTGATCAATGCAAGTGGAGTGGTTATACAC
ACAAACCTTGGTAGAAGTGTAATCCATGAAGAACTTTATGAAGCGTGTAAAGATATCATTTGTAATTATTCTAATGTAGA
GTTTGATTTAGAAAATGGAAAAAGAGGCTCTCGCTATGCTTTGGTGTTGGAAAAACTTAAAATGCTTTTTGAATGCGAAG
ATGCTTTAGTAGTCAATAACAACGCTGCGGCAGTTTTTTTAGTGCTTAATTCTCTTTGTTATGATAAAGAAGTCATAAGC
TCAAGAGGAGAACTTGTAGAAATTGGCGGAAGTTTTCGTGTGCCTGAAGTGATAAAAGCTGCAGGTGTAAAGCTTTGCGA
AGTTGGAACTAGTAACAAAACACACTTAAAAGACTATGAACAAGCTATCGGTGAAAATACCGCTCTAATTTTAAAAACCC
ACAAGTCTAATTTCGCTCTTATGGGTTTTCACAGTGAAGTAAATATAAAAGATCTACATGAACTAGCAAAAGAAAAAGGG
CTTTTGAGTTATTATGATCTAGGTTCTGGCTGGTGTGAAAATTTAAATGAAAAGCTGATTAAAAATGAACCTAAAATCAA
AAAACTCGTACAAGAATGTGATATTTTAAGTTTTAGTGGAGATAAACTTTTTGGTAGTGCGCAAGCAGGCATTATACTTG
GAAAAAAAGAACTCATAGAAAAACTTAAACAAAATCAACTTTTAAGAATGCTAAGAGTGGATAAATTAACTCTATCTTTT
TTAAACGAAAGCTTAAAAGCTTATTTGCAAAAAGATTATAAAAAAATTATTACCTTAAAACTTTTAAATGATGACTTATC
CTTTATAGAAAAAAAAGCTTTAAGAGTGCAAAAAGAATTAAATTTTCAAACCCAGCTTAAAAAAAGCAAAAGTTTAGTAG
GAGGAGGTTCTATGCCTGATAAAAGTTTAGATACTTATATACTAACTTTTCAAGGAGATGCTTTAAAACTACAAACTCGA
TTTAGAAAAGAAAATATCATAGGACGCATTGAAAATGATGAATTTGTTCTTGATTTTAGAACTATACGAGAAAATGAACT
TCAAAAACTTATTCTTACAATCAATCAAATGGAAAACTTATGA

Upstream 100 bases:

>100_bases
TTTATATAAACAAAATCTTGCATTGTCTTCCTTAATCTCTTTAAAACATCATTTTATAAATTCTATGTTAAAATAACCAA
ATATTTTCTTAAGGCTTAAG

Downstream 100 bases:

>100_bases
AGTCTGTTATTATAGGAACTGCAGGACATATTGATCATGGAAAAACTTCACTCATTAAAGCTTTAAATGGTTTTGAAGGT
GATAGTTTAAAAGAAGAACA

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MNKFRTFPQINTLIEDESLKSYPFYIKVFFCKKVVAKLKENFSQDEISKDKLLLEIKKEIKTFYRKDLQSVINASGVVIH
TNLGRSVIHEELYEACKDIICNYSNVEFDLENGKRGSRYALVLEKLKMLFECEDALVVNNNAAAVFLVLNSLCYDKEVIS
SRGELVEIGGSFRVPEVIKAAGVKLCEVGTSNKTHLKDYEQAIGENTALILKTHKSNFALMGFHSEVNIKDLHELAKEKG
LLSYYDLGSGWCENLNEKLIKNEPKIKKLVQECDILSFSGDKLFGSAQAGIILGKKELIEKLKQNQLLRMLRVDKLTLSF
LNESLKAYLQKDYKKIITLKLLNDDLSFIEKKALRVQKELNFQTQLKKSKSLVGGGSMPDKSLDTYILTFQGDALKLQTR
FRKENIIGRIENDEFVLDFRTIRENELQKLILTINQMENL

Sequences:

>Translated_440_residues
MNKFRTFPQINTLIEDESLKSYPFYIKVFFCKKVVAKLKENFSQDEISKDKLLLEIKKEIKTFYRKDLQSVINASGVVIH
TNLGRSVIHEELYEACKDIICNYSNVEFDLENGKRGSRYALVLEKLKMLFECEDALVVNNNAAAVFLVLNSLCYDKEVIS
SRGELVEIGGSFRVPEVIKAAGVKLCEVGTSNKTHLKDYEQAIGENTALILKTHKSNFALMGFHSEVNIKDLHELAKEKG
LLSYYDLGSGWCENLNEKLIKNEPKIKKLVQECDILSFSGDKLFGSAQAGIILGKKELIEKLKQNQLLRMLRVDKLTLSF
LNESLKAYLQKDYKKIITLKLLNDDLSFIEKKALRVQKELNFQTQLKKSKSLVGGGSMPDKSLDTYILTFQGDALKLQTR
FRKENIIGRIENDEFVLDFRTIRENELQKLILTINQMENL
>Mature_440_residues
MNKFRTFPQINTLIEDESLKSYPFYIKVFFCKKVVAKLKENFSQDEISKDKLLLEIKKEIKTFYRKDLQSVINASGVVIH
TNLGRSVIHEELYEACKDIICNYSNVEFDLENGKRGSRYALVLEKLKMLFECEDALVVNNNAAAVFLVLNSLCYDKEVIS
SRGELVEIGGSFRVPEVIKAAGVKLCEVGTSNKTHLKDYEQAIGENTALILKTHKSNFALMGFHSEVNIKDLHELAKEKG
LLSYYDLGSGWCENLNEKLIKNEPKIKKLVQECDILSFSGDKLFGSAQAGIILGKKELIEKLKQNQLLRMLRVDKLTLSF
LNESLKAYLQKDYKKIITLKLLNDDLSFIEKKALRVQKELNFQTQLKKSKSLVGGGSMPDKSLDTYILTFQGDALKLQTR
FRKENIIGRIENDEFVLDFRTIRENELQKLILTINQMENL

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=404, Percent_Identity=39.1089108910891, Blast_Score=251, Evalue=5e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 50380; Mature: 50380

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKFRTFPQINTLIEDESLKSYPFYIKVFFCKKVVAKLKENFSQDEISKDKLLLEIKKEI
CCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
KTFYRKDLQSVINASGVVIHTNLGRSVIHEELYEACKDIICNYSNVEFDLENGKRGSRYA
HHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHH
LVLEKLKMLFECEDALVVNNNAAAVFLVLNSLCYDKEVISSRGELVEIGGSFRVPEVIKA
HHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHCCHHHHHCCCCEEEECCCCCCHHHHHH
AGVKLCEVGTSNKTHLKDYEQAIGENTALILKTHKSNFALMGFHSEVNIKDLHELAKEKG
CCCEEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHCC
LLSYYDLGSGWCENLNEKLIKNEPKIKKLVQECDILSFSGDKLFGSAQAGIILGKKELIE
CEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHCCEEECCCCCEECCCCCCEEECHHHHHH
KLKQNQLLRMLRVDKLTLSFLNESLKAYLQKDYKKIITLKLLNDDLSFIEKKALRVQKEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHC
NFQTQLKKSKSLVGGGSMPDKSLDTYILTFQGDALKLQTRFRKENIIGRIENDEFVLDFR
CHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCEEEHHHHHHHHCCCEEECCCCEEEEHH
TIRENELQKLILTINQMENL
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKFRTFPQINTLIEDESLKSYPFYIKVFFCKKVVAKLKENFSQDEISKDKLLLEIKKEI
CCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
KTFYRKDLQSVINASGVVIHTNLGRSVIHEELYEACKDIICNYSNVEFDLENGKRGSRYA
HHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHH
LVLEKLKMLFECEDALVVNNNAAAVFLVLNSLCYDKEVISSRGELVEIGGSFRVPEVIKA
HHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHCCHHHHHCCCCEEEECCCCCCHHHHHH
AGVKLCEVGTSNKTHLKDYEQAIGENTALILKTHKSNFALMGFHSEVNIKDLHELAKEKG
CCCEEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHCC
LLSYYDLGSGWCENLNEKLIKNEPKIKKLVQECDILSFSGDKLFGSAQAGIILGKKELIE
CEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHCCEEECCCCCEECCCCCCEEECHHHHHH
KLKQNQLLRMLRVDKLTLSFLNESLKAYLQKDYKKIITLKLLNDDLSFIEKKALRVQKEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHC
NFQTQLKKSKSLVGGGSMPDKSLDTYILTFQGDALKLQTRFRKENIIGRIENDEFVLDFR
CHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCEEEHHHHHHHHCCCEEECCCCEEEEHH
TIRENELQKLILTINQMENL
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA