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The map label for this gene is cdsA [H]

Identifier: 57238390

GI number: 57238390

Start: 1432643

End: 1433368

Strand: Reverse

Name: cdsA [H]

Synonym: CJE1536

Alternate gene names: 57238390

Gene position: 1433368-1432643 (Counterclockwise)

Preceding gene: 57238391

Following gene: 57238389

Centisome position: 80.62

GC content: 34.3

Gene sequence:

>726_bases
ATGTTTAATACAACTAGAATTATTTCAGCTCTTGTGATGATAGGGGCTATTATTATTATCGCGTTGATTGATCAATTTTT
TATCAATTTTATCGTTTTTGCGGTTTTATTGTATCTATCTTTTAGTGAAGCAAAAAAACTTTTTGCTTTAGAAAATATCT
CTATTATCCCTTTGGCTATAGCTTTTATTTTGGGAAGTTTGTCGCATAAAGCTTTGCTTTTTGGGATTTTAGCTTTGTTA
TTAGTCGTTGGATATTTGGTTTATAAAAAGGCTTCTTTAAAACCAGCTCTTATTTATATTTATCCTAGTTTGCCTATTTT
AGCACTTTGGCAAGTGTATTTAGATCAGGGTATGTTTGCACTTTTTTGGCTTATCATTATCGTTGCAGCTTGTGATAGTG
GGGCGTATTTTATCGGAAAACTTATGGGTAAAACTCCTTTTTCTCCAACAAGCCCAAACAAAACCTTAGAAGGTGTTATA
GGTGGCTTGATTTGTGCGAGTGTTATTGGAACTATTTTGGGAGTTTTTGTTTATAGTTTTTGGCTTTCTTTGCTTTGTTC
GTTTTTTGTAGCGATTTTTGCAGTGATTGGAGATTTGCTTGAGAGTTATTTTAAAAGAGAAGCAGGTGTAAAAGATAGTG
GAGATCTTATCCCTGGTCATGGGGGCATGCTCGATAGGATCGATGCGGTGATCATTGCTGCTTTTGTGATGGTTGCTCTT
TTATGA

Upstream 100 bases:

>100_bases
CCAGCGATGATGAGAAAAATGAAGAAGATGAGTCTAAAGATCCAAATTTTAAAGACGCACAAAGCATTCATCGCTTAGAT
ATTAGTATATAAGGAAAAAT

Downstream 100 bases:

>100_bases
TACTTTTTGGAAGTACGGGCAGTATAGGAGTAAATGCTCTTAAACTTGCTGCTTTAAAAAACATTCCCATTTCTGCTTTA
GCTTGTGGGGATAACATCGC

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MFNTTRIISALVMIGAIIIIALIDQFFINFIVFAVLLYLSFSEAKKLFALENISIIPLAIAFILGSLSHKALLFGILALL
LVVGYLVYKKASLKPALIYIYPSLPILALWQVYLDQGMFALFWLIIIVAACDSGAYFIGKLMGKTPFSPTSPNKTLEGVI
GGLICASVIGTILGVFVYSFWLSLLCSFFVAIFAVIGDLLESYFKREAGVKDSGDLIPGHGGMLDRIDAVIIAAFVMVAL
L

Sequences:

>Translated_241_residues
MFNTTRIISALVMIGAIIIIALIDQFFINFIVFAVLLYLSFSEAKKLFALENISIIPLAIAFILGSLSHKALLFGILALL
LVVGYLVYKKASLKPALIYIYPSLPILALWQVYLDQGMFALFWLIIIVAACDSGAYFIGKLMGKTPFSPTSPNKTLEGVI
GGLICASVIGTILGVFVYSFWLSLLCSFFVAIFAVIGDLLESYFKREAGVKDSGDLIPGHGGMLDRIDAVIIAAFVMVAL
L
>Mature_241_residues
MFNTTRIISALVMIGAIIIIALIDQFFINFIVFAVLLYLSFSEAKKLFALENISIIPLAIAFILGSLSHKALLFGILALL
LVVGYLVYKKASLKPALIYIYPSLPILALWQVYLDQGMFALFWLIIIVAACDSGAYFIGKLMGKTPFSPTSPNKTLEGVI
GGLICASVIGTILGVFVYSFWLSLLCSFFVAIFAVIGDLLESYFKREAGVKDSGDLIPGHGGMLDRIDAVIIAAFVMVAL
L

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=149, Percent_Identity=45.6375838926174, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787677, Length=108, Percent_Identity=42.5925925925926, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 26189; Mature: 26189

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNTTRIISALVMIGAIIIIALIDQFFINFIVFAVLLYLSFSEAKKLFALENISIIPLAI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
AFILGSLSHKALLFGILALLLVVGYLVYKKASLKPALIYIYPSLPILALWQVYLDQGMFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCHHH
LFWLIIIVAACDSGAYFIGKLMGKTPFSPTSPNKTLEGVIGGLICASVIGTILGVFVYSF
HHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLSLLCSFFVAIFAVIGDLLESYFKREAGVKDSGDLIPGHGGMLDRIDAVIIAAFVMVAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
L
C
>Mature Secondary Structure
MFNTTRIISALVMIGAIIIIALIDQFFINFIVFAVLLYLSFSEAKKLFALENISIIPLAI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
AFILGSLSHKALLFGILALLLVVGYLVYKKASLKPALIYIYPSLPILALWQVYLDQGMFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCHHH
LFWLIIIVAACDSGAYFIGKLMGKTPFSPTSPNKTLEGVIGGLICASVIGTILGVFVYSF
HHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLSLLCSFFVAIFAVIGDLLESYFKREAGVKDSGDLIPGHGGMLDRIDAVIIAAFVMVAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]