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The map label for this gene is lptD [H]

Identifier: 57238126

GI number: 57238126

Start: 1302255

End: 1304303

Strand: Direct

Name: lptD [H]

Synonym: CJE1389

Alternate gene names: 57238126

Gene position: 1302255-1304303 (Clockwise)

Preceding gene: 57238125

Following gene: 57238127

Centisome position: 73.25

GC content: 31.53

Gene sequence:

>2049_bases
ATGTGGCGTAAATTTTCCCTATTGCTAGGAACTAGTATAGCTTTAAATGCAGCACAAGTTGATATTTACGCTCTTGATGT
AAAAAAAGAAGGTGATATTCTTACTGCAAACAATGATGTTATTATTTTTTCTGATTTTTATTTCATCACTGCTAATAAAG
CAATTTACAATGAAAAAACCGGAGATGTTGAGCTTTTTGGCGATGTTAACATCCTAAGGGGACAAAACGAAAGATCACAT
TCTGATTATGCTAAAATCAACCTAAATTCCAATCAAGCCGATTTTAGTAATTTTTTCTTTTCCAATAACAATCTTGAAGT
ATGGTTTCAAAGCAAAACAAGTCATCTAAATGATAAAGTCTTTGAAAGCAAAGTTTCAGCAGTTTCAAGCTGCAATGTTG
AAGATCCTGATTGGGAAATTCGTTTTTCAAAAGGCTGGCTTAACCGGGAAACCAATTTTGTTCATCTTTACAATGCAAGA
TTATATGTTAAAAATACCCCAGTTTTTTATCTACCTTATTTTGGATTTAGCGCTGATACTCATAGACAAAGCGGGCTTTT
AATCCCAAAAATCGTTTTAAAAAGTAGCGAAGGCTTATACTATGAACAACCTATTTATATAGCCACTCAAGAAAATTGGG
ATTTAGAACTTAATCCACAAATTCGAACAAACCGTGGTTTTGGACTTTATTCTACTTTAAGATTTCTTGATTCTCCATAT
TCAACAGGAGAATTAAATTTTGGTGCTTTTAGGGAAAATAGCTCCTATTTTCACGATGAAAATTTAAAAAATCAAACCCA
CTATGGAATAGAACTAAAATACTCAAGAGATGATTTAATCAAATCTTTACTCAGTGATAATTTTCAAGAAGGCCTATGGA
TAGATGCAACCTATCTCAACGATGTGGATTATTTAAATTTAGGAAGTAGGGATTATCGAGATCTTAACTCGCTTGTAACC
TCCAAAATCAATTATTTTTTAGCTGATGAAAACAATTTTTACGGAGCTTATGCAAGATATTATATCGACACATCTAAACT
TAGCAACAATACAACCTTACAAGAATATCCAAGCTTTCAATATCATAGATTTTTAAATAACCTTTTTGATGAACGCTTGC
GTTATTCATTTGATGCTTCATTTCATAATTTTTACCGACCTGCTGGTTCTTATGCAAATGAGCTAAATTTAGACTTGCCT
ATCTCGTATCACAACGCTTTTTTTGGAGACTTTTTACACTTTACTTTTACAGAAAGATTTTATGCTTCTTTTGTAAATTA
TAGCAACGATCCCGAAAGAAACCATGAGCATTATTTCAGAAACACTCATGATTTTAATCTCTACACCGATCTTTCAAAAG
CTTATGAAAATTTCTTTCATACTTTAAATTTAGGGGTGAATTACATTTTACCAGGAGCAAAATCAGGTAAAATCACGCAA
GATTATCTTGAAGAATACGACAAAGAAAACGAACATACAAGTCTTTATGCTGTGCAATATTTCTATAACAACGAAGGACA
AAAAAAACTCAAACACAGAATTTCACTTGACTATCTCAATAAACAAAATGAATTCTATGAACTTGAAAATCTTTTAACTT
ATTATTTTAATGAAAATATCAATCTCAACAGCGAAGTGCTTTACTCTTATGAACAAAGTCGCTTTACCAATGTCATCAGC
CAAATAGAAGTCAATACAAATTCAAAATTTAATTGGATGTTTTCTCATGCTTATCAAAACGATGAGTATGGAAAATATAG
CTTTATTGGCACAAGAGCAAATTATATTGCCACACCTAATTACAATTTATTTGGTGGAATTTGGTTTGATACTCAAAGAG
CTCATGCAAACATGTGGGAACTTGGCTATACCTACCAAAGAAAATGTTGGAACTATTCTTTAATGTATAGAGAAAGAATC
GATCCACAACTCACAAGTGGTGGTATCACAGCTAAAAATCAAAGCGGAGTTTATTTTATTTTCAACTTCTATCCTTTAGG
AGGAGTAAAATACGATTTCTCTTTAGCAGAAAGTGAAAACAAAATTTAA

Upstream 100 bases:

>100_bases
CAAGTTAGTGCTATGGCGTTTATGCTTGGATTTGCTTGGGCTTTAAGCAATGATTTACGCAAAGCTTGGGAGGATTATCT
AGCAAGGACAATAGTAGTCG

Downstream 100 bases:

>100_bases
AAAGGATGAAATTTGCTAAATATTTTAAAAAATTTTACGAATTTATTATCTGGTAAAAAAGGAAAAATAATGCAATACAG
CATAGAAATTAACAAAAATA

Product: organic solvent tolerance protein

Products: NA

Alternate protein names: Organic solvent tolerance protein [H]

Number of amino acids: Translated: 682; Mature: 682

Protein sequence:

>682_residues
MWRKFSLLLGTSIALNAAQVDIYALDVKKEGDILTANNDVIIFSDFYFITANKAIYNEKTGDVELFGDVNILRGQNERSH
SDYAKINLNSNQADFSNFFFSNNNLEVWFQSKTSHLNDKVFESKVSAVSSCNVEDPDWEIRFSKGWLNRETNFVHLYNAR
LYVKNTPVFYLPYFGFSADTHRQSGLLIPKIVLKSSEGLYYEQPIYIATQENWDLELNPQIRTNRGFGLYSTLRFLDSPY
STGELNFGAFRENSSYFHDENLKNQTHYGIELKYSRDDLIKSLLSDNFQEGLWIDATYLNDVDYLNLGSRDYRDLNSLVT
SKINYFLADENNFYGAYARYYIDTSKLSNNTTLQEYPSFQYHRFLNNLFDERLRYSFDASFHNFYRPAGSYANELNLDLP
ISYHNAFFGDFLHFTFTERFYASFVNYSNDPERNHEHYFRNTHDFNLYTDLSKAYENFFHTLNLGVNYILPGAKSGKITQ
DYLEEYDKENEHTSLYAVQYFYNNEGQKKLKHRISLDYLNKQNEFYELENLLTYYFNENINLNSEVLYSYEQSRFTNVIS
QIEVNTNSKFNWMFSHAYQNDEYGKYSFIGTRANYIATPNYNLFGGIWFDTQRAHANMWELGYTYQRKCWNYSLMYRERI
DPQLTSGGITAKNQSGVYFIFNFYPLGGVKYDFSLAESENKI

Sequences:

>Translated_682_residues
MWRKFSLLLGTSIALNAAQVDIYALDVKKEGDILTANNDVIIFSDFYFITANKAIYNEKTGDVELFGDVNILRGQNERSH
SDYAKINLNSNQADFSNFFFSNNNLEVWFQSKTSHLNDKVFESKVSAVSSCNVEDPDWEIRFSKGWLNRETNFVHLYNAR
LYVKNTPVFYLPYFGFSADTHRQSGLLIPKIVLKSSEGLYYEQPIYIATQENWDLELNPQIRTNRGFGLYSTLRFLDSPY
STGELNFGAFRENSSYFHDENLKNQTHYGIELKYSRDDLIKSLLSDNFQEGLWIDATYLNDVDYLNLGSRDYRDLNSLVT
SKINYFLADENNFYGAYARYYIDTSKLSNNTTLQEYPSFQYHRFLNNLFDERLRYSFDASFHNFYRPAGSYANELNLDLP
ISYHNAFFGDFLHFTFTERFYASFVNYSNDPERNHEHYFRNTHDFNLYTDLSKAYENFFHTLNLGVNYILPGAKSGKITQ
DYLEEYDKENEHTSLYAVQYFYNNEGQKKLKHRISLDYLNKQNEFYELENLLTYYFNENINLNSEVLYSYEQSRFTNVIS
QIEVNTNSKFNWMFSHAYQNDEYGKYSFIGTRANYIATPNYNLFGGIWFDTQRAHANMWELGYTYQRKCWNYSLMYRERI
DPQLTSGGITAKNQSGVYFIFNFYPLGGVKYDFSLAESENKI
>Mature_682_residues
MWRKFSLLLGTSIALNAAQVDIYALDVKKEGDILTANNDVIIFSDFYFITANKAIYNEKTGDVELFGDVNILRGQNERSH
SDYAKINLNSNQADFSNFFFSNNNLEVWFQSKTSHLNDKVFESKVSAVSSCNVEDPDWEIRFSKGWLNRETNFVHLYNAR
LYVKNTPVFYLPYFGFSADTHRQSGLLIPKIVLKSSEGLYYEQPIYIATQENWDLELNPQIRTNRGFGLYSTLRFLDSPY
STGELNFGAFRENSSYFHDENLKNQTHYGIELKYSRDDLIKSLLSDNFQEGLWIDATYLNDVDYLNLGSRDYRDLNSLVT
SKINYFLADENNFYGAYARYYIDTSKLSNNTTLQEYPSFQYHRFLNNLFDERLRYSFDASFHNFYRPAGSYANELNLDLP
ISYHNAFFGDFLHFTFTERFYASFVNYSNDPERNHEHYFRNTHDFNLYTDLSKAYENFFHTLNLGVNYILPGAKSGKITQ
DYLEEYDKENEHTSLYAVQYFYNNEGQKKLKHRISLDYLNKQNEFYELENLLTYYFNENINLNSEVLYSYEQSRFTNVIS
QIEVNTNSKFNWMFSHAYQNDEYGKYSFIGTRANYIATPNYNLFGGIWFDTQRAHANMWELGYTYQRKCWNYSLMYRERI
DPQLTSGGITAKNQSGVYFIFNFYPLGGVKYDFSLAESENKI

Specific function: Involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis [H]

COG id: COG1452

COG function: function code M; Organic solvent tolerance protein OstA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptD family [H]

Homologues:

None

Paralogues:

None

Copy number: 60 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020889
- InterPro:   IPR007543 [H]

Pfam domain/function: PF04453 OstA_C [H]

EC number: NA

Molecular weight: Translated: 80439; Mature: 80439

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWRKFSLLLGTSIALNAAQVDIYALDVKKEGDILTANNDVIIFSDFYFITANKAIYNEKT
CCEEEEEEECCEEEEEEEEEEEEEEEECCCCCEEECCCCEEEEEEEEEEEECCEEECCCC
GDVELFGDVNILRGQNERSHSDYAKINLNSNQADFSNFFFSNNNLEVWFQSKTSHLNDKV
CCEEEEECEEEEECCCCCCCCCEEEEEECCCCCCCCCEEEECCCEEEEEECCCCCCHHHH
FESKVSAVSSCNVEDPDWEIRFSKGWLNRETNFVHLYNARLYVKNTPVFYLPYFGFSADT
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEEEEEEEEEECCCEEEEECCCCCCCC
HRQSGLLIPKIVLKSSEGLYYEQPIYIATQENWDLELNPQIRTNRGFGLYSTLRFLDSPY
CCCCCEEEEEEEEECCCCCEEECCEEEEECCCCCEEECCCEECCCCCCHHHHHHHHCCCC
STGELNFGAFRENSSYFHDENLKNQTHYGIELKYSRDDLIKSLLSDNFQEGLWIDATYLN
CCCCEECCEEECCCCCCCCCCCCCCCEEEEEEEECHHHHHHHHHHCCCCCCEEEEEEEEC
DVDYLNLGSRDYRDLNSLVTSKINYFLADENNFYGAYARYYIDTSKLSNNTTLQEYPSFQ
CCCEECCCCCCHHHHHHHHHHCCEEEEECCCCCEEEEEEEEEEHHHCCCCCCHHHCCCHH
YHRFLNNLFDERLRYSFDASFHNFYRPAGSYANELNLDLPISYHNAFFGDFLHFTFTERF
HHHHHHHHHHHHHHEEECCCHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHH
YASFVNYSNDPERNHEHYFRNTHDFNLYTDLSKAYENFFHTLNLGVNYILPGAKSGKITQ
HHHHHCCCCCCCCCCHHHCCCCCCCEEEHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCH
DYLEEYDKENEHTSLYAVQYFYNNEGQKKLKHRISLDYLNKQNEFYELENLLTYYFNENI
HHHHHHCCCCCCCEEEEEEEEECCCCHHHHHHHHHHEECCCCCHHHHHHHHHEEEECCCC
NLNSEVLYSYEQSRFTNVISQIEVNTNSKFNWMFSHAYQNDEYGKYSFIGTRANYIATPN
CCCHHHEEEHHHHHHHHHHHEEEECCCCEEEEEEEECCCCCCCCCEEEEECCCCEEECCC
YNLFGGIWFDTQRAHANMWELGYTYQRKCWNYSLMYRERIDPQLTSGGITAKNQSGVYFI
CCEEEEEEEECCCCCCCHHHCCCHHHHHHCCEEEEEHHCCCCCCCCCCEEECCCCCEEEE
FNFYPLGGVKYDFSLAESENKI
EEEEECCCEEEEEEECCCCCCC
>Mature Secondary Structure
MWRKFSLLLGTSIALNAAQVDIYALDVKKEGDILTANNDVIIFSDFYFITANKAIYNEKT
CCEEEEEEECCEEEEEEEEEEEEEEEECCCCCEEECCCCEEEEEEEEEEEECCEEECCCC
GDVELFGDVNILRGQNERSHSDYAKINLNSNQADFSNFFFSNNNLEVWFQSKTSHLNDKV
CCEEEEECEEEEECCCCCCCCCEEEEEECCCCCCCCCEEEECCCEEEEEECCCCCCHHHH
FESKVSAVSSCNVEDPDWEIRFSKGWLNRETNFVHLYNARLYVKNTPVFYLPYFGFSADT
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEEEEEEEEEECCCEEEEECCCCCCCC
HRQSGLLIPKIVLKSSEGLYYEQPIYIATQENWDLELNPQIRTNRGFGLYSTLRFLDSPY
CCCCCEEEEEEEEECCCCCEEECCEEEEECCCCCEEECCCEECCCCCCHHHHHHHHCCCC
STGELNFGAFRENSSYFHDENLKNQTHYGIELKYSRDDLIKSLLSDNFQEGLWIDATYLN
CCCCEECCEEECCCCCCCCCCCCCCCEEEEEEEECHHHHHHHHHHCCCCCCEEEEEEEEC
DVDYLNLGSRDYRDLNSLVTSKINYFLADENNFYGAYARYYIDTSKLSNNTTLQEYPSFQ
CCCEECCCCCCHHHHHHHHHHCCEEEEECCCCCEEEEEEEEEEHHHCCCCCCHHHCCCHH
YHRFLNNLFDERLRYSFDASFHNFYRPAGSYANELNLDLPISYHNAFFGDFLHFTFTERF
HHHHHHHHHHHHHHEEECCCHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHH
YASFVNYSNDPERNHEHYFRNTHDFNLYTDLSKAYENFFHTLNLGVNYILPGAKSGKITQ
HHHHHCCCCCCCCCCHHHCCCCCCCEEEHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCH
DYLEEYDKENEHTSLYAVQYFYNNEGQKKLKHRISLDYLNKQNEFYELENLLTYYFNENI
HHHHHHCCCCCCCEEEEEEEEECCCCHHHHHHHHHHEECCCCCHHHHHHHHHEEEECCCC
NLNSEVLYSYEQSRFTNVISQIEVNTNSKFNWMFSHAYQNDEYGKYSFIGTRANYIATPN
CCCHHHEEEHHHHHHHHHHHEEEECCCCEEEEEEEECCCCCCCCCEEEEECCCCEEECCC
YNLFGGIWFDTQRAHANMWELGYTYQRKCWNYSLMYRERIDPQLTSGGITAKNQSGVYFI
CCEEEEEEEECCCCCCCHHHCCCHHHHHHCCEEEEEHHCCCCCCCCCCEEECCCCCEEEE
FNFYPLGGVKYDFSLAESENKI
EEEEECCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12704232 [H]