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The map label for this gene is luxS

Identifier: 57238070

GI number: 57238070

Start: 1248216

End: 1248710

Strand: Direct

Name: luxS

Synonym: CJE1332

Alternate gene names: 57238070

Gene position: 1248216-1248710 (Clockwise)

Preceding gene: 57238066

Following gene: 57238071

Centisome position: 70.21

GC content: 33.94

Gene sequence:

>495_bases
ATGCCATTATTAGACAGCTTTAAAGTTGACCATACTAAAATGCCAGCTCCTGCTGTGCGTTTAGCTAAAGTTATGAAAAC
ACCTAAGGGTGATGATATTAGCGTGTTTGATTTGCGTTTTTGCATACCAAATAAAGACATTATGAGCGAAAAAGGTACTC
ATACCTTAGAACATTTATTTGCAGGATTTATGAGAGATCATCTTAATTCAAATTCAGTTGAAATTATTGATATTTCACCT
ATGGGTTGTCGCACGGGTTTTTATATGAGTTTAATTGGAACACCAGATGAAAAAAGTGTTGCAAAAGCTTGGGAAGAAGC
TATGAAAGATGTTTTAAGCGTAAGCGATCAAAGCAAAATTCCTGAACTTAATATCTATCAATGCGGAACTTGCGCAATGC
ATTCTTTAGATGAAGCCAAACAAATTGCCCAAAAGGTTTTAAATCTAGGTATTAGCATAATGAATAACAAAGAATTAAAA
CTCGAGAATGCTTAA

Upstream 100 bases:

>100_bases
TTTTTAAATGTTTTATTTTATCTTTTTTTCTTTTAGAAAGGCTTTAAATATTAACTTTAAATGCTATAATTCTTAGACAA
TTTATATTTAAGGAGTTAAA

Downstream 100 bases:

>100_bases
AAAGAATCTTTATTTTTTAAACGATTAAGCTTTAATTAATATATTTTTATATATGATTTTGAAATTTTATTATTTTAAAA
GGAGAAAAAATGAAACTGAT

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MPLLDSFKVDHTKMPAPAVRLAKVMKTPKGDDISVFDLRFCIPNKDIMSEKGTHTLEHLFAGFMRDHLNSNSVEIIDISP
MGCRTGFYMSLIGTPDEKSVAKAWEEAMKDVLSVSDQSKIPELNIYQCGTCAMHSLDEAKQIAQKVLNLGISIMNNKELK
LENA

Sequences:

>Translated_164_residues
MPLLDSFKVDHTKMPAPAVRLAKVMKTPKGDDISVFDLRFCIPNKDIMSEKGTHTLEHLFAGFMRDHLNSNSVEIIDISP
MGCRTGFYMSLIGTPDEKSVAKAWEEAMKDVLSVSDQSKIPELNIYQCGTCAMHSLDEAKQIAQKVLNLGISIMNNKELK
LENA
>Mature_163_residues
PLLDSFKVDHTKMPAPAVRLAKVMKTPKGDDISVFDLRFCIPNKDIMSEKGTHTLEHLFAGFMRDHLNSNSVEIIDISPM
GCRTGFYMSLIGTPDEKSVAKAWEEAMKDVLSVSDQSKIPELNIYQCGTCAMHSLDEAKQIAQKVLNLGISIMNNKELKL
ENA

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family

Homologues:

Organism=Escherichia coli, GI1789043, Length=161, Percent_Identity=71.4285714285714, Blast_Score=256, Evalue=7e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUXS_CAMJ8 (A8FMQ4)

Other databases:

- EMBL:   CP000814
- RefSeq:   YP_001482718.1
- ProteinModelPortal:   A8FMQ4
- SMR:   A8FMQ4
- STRING:   A8FMQ4
- GeneID:   5617111
- GenomeReviews:   CP000814_GR
- KEGG:   cju:C8J_1142
- eggNOG:   COG1854
- HOGENOM:   HBG347473
- OMA:   VRIAKTM
- ProtClustDB:   PRK02260
- BioCyc:   CJEJ407148:C8J_1142-MONOMER
- HAMAP:   MF_00091
- InterPro:   IPR011249
- InterPro:   IPR003815
- Gene3D:   G3DSA:3.30.1360.80
- PIRSF:   PIRSF006160
- PRINTS:   PR01487
- ProDom:   PD013172

Pfam domain/function: PF02664 LuxS; SSF63411 Metalloenz_metal-bd

EC number: =4.4.1.21

Molecular weight: Translated: 18271; Mature: 18140

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDSFKVDHTKMPAPAVRLAKVMKTPKGDDISVFDLRFCIPNKDIMSEKGTHTLEHLF
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEEEECCCHHHHHCCCCHHHHHHH
AGFMRDHLNSNSVEIIDISPMGCRTGFYMSLIGTPDEKSVAKAWEEAMKDVLSVSDQSKI
HHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCC
PELNIYQCGTCAMHSLDEAKQIAQKVLNLGISIMNNKELKLENA
CCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEECCC
>Mature Secondary Structure 
PLLDSFKVDHTKMPAPAVRLAKVMKTPKGDDISVFDLRFCIPNKDIMSEKGTHTLEHLF
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEEEECCCHHHHHCCCCHHHHHHH
AGFMRDHLNSNSVEIIDISPMGCRTGFYMSLIGTPDEKSVAKAWEEAMKDVLSVSDQSKI
HHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCC
PELNIYQCGTCAMHSLDEAKQIAQKVLNLGISIMNNKELKLENA
CCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA