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The map label for this gene is mdtJ [H]

Identifier: 57238045

GI number: 57238045

Start: 1222267

End: 1222608

Strand: Direct

Name: mdtJ [H]

Synonym: CJE1307

Alternate gene names: 57238045

Gene position: 1222267-1222608 (Clockwise)

Preceding gene: 57238039

Following gene: 57238046

Centisome position: 68.75

GC content: 27.49

Gene sequence:

>342_bases
TTGAATATCGCAAAAAAAGAACTTTTTGTTGCTTGGTTTTTCTTGATTGCTGCTATTGTATTTGAAGTTTTAGGCACTAG
TTTTTTAAAAATGGAAAATCAAGTTTTAGGCTATATATTTATGGCTTTATTTATAGCTTTTTCTTATTTTTTTATGGGCA
AGGCGATTAAAAAAATTCAAGTAGGTATAGCCTATGCTGTATGGGAACTTTTAGGGATTATTCTTATACTTTTAGTTTCT
TTTATAGTTTTTAAAGAGAGTTTAACCTTAACTCAAATTCTAGGCATTATTCTTTCTATCGTTGGAATTATCATGATTAA
TATAGGCGAGGTTAAAGAATAA

Upstream 100 bases:

>100_bases
TCTCACTTTCTTTAAAGATTTTTAAACTTAAAAGTATAAACTAAAAAGGCTAATTAAAGCTTTAAATGGTATGATTTTAT
TATTTTTGGGGAGAAGCTTT

Downstream 100 bases:

>100_bases
TGTATATTTTTATCATTGTTTTATCAGCATTGTTAGATATCGTAGCAAATTTATTGCTAAAAAAATCAGATGGTTTTAAG
CATAAAATTTGGGGCTTGGC

Product: SMR family multidrug efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MNIAKKELFVAWFFLIAAIVFEVLGTSFLKMENQVLGYIFMALFIAFSYFFMGKAIKKIQVGIAYAVWELLGIILILLVS
FIVFKESLTLTQILGIILSIVGIIMINIGEVKE

Sequences:

>Translated_113_residues
MNIAKKELFVAWFFLIAAIVFEVLGTSFLKMENQVLGYIFMALFIAFSYFFMGKAIKKIQVGIAYAVWELLGIILILLVS
FIVFKESLTLTQILGIILSIVGIIMINIGEVKE
>Mature_113_residues
MNIAKKELFVAWFFLIAAIVFEVLGTSFLKMENQVLGYIFMALFIAFSYFFMGKAIKKIQVGIAYAVWELLGIILILLVS
FIVFKESLTLTQILGIILSIVGIIMINIGEVKE

Specific function: Catalyzes the excretion of spermidine [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. MdtJ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787884, Length=108, Percent_Identity=38.8888888888889, Blast_Score=71, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 12745; Mature: 12745

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIAKKELFVAWFFLIAAIVFEVLGTSFLKMENQVLGYIFMALFIAFSYFFMGKAIKKIQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGIAYAVWELLGIILILLVSFIVFKESLTLTQILGIILSIVGIIMINIGEVKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNIAKKELFVAWFFLIAAIVFEVLGTSFLKMENQVLGYIFMALFIAFSYFFMGKAIKKIQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGIAYAVWELLGIILILLVSFIVFKESLTLTQILGIILSIVGIIMINIGEVKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA