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The map label for this gene is asd [H]

Identifier: 57237910

GI number: 57237910

Start: 1082498

End: 1083529

Strand: Reverse

Name: asd [H]

Synonym: CJE1167

Alternate gene names: 57237910

Gene position: 1083529-1082498 (Counterclockwise)

Preceding gene: 57237911

Following gene: 57237909

Centisome position: 60.95

GC content: 32.27

Gene sequence:

>1032_bases
ATGTCAAAAAAACAAAAAATAGCCATTGTGGGTGCTACTGGTGCGGTTGGGGAAGAGCTTTTAAATGTTTTAGATGAACT
TGATTTCCCAGTGGAAAGTATTTTACCTTTAGCAAGTGCAAAAAGTGTAGGTAGTGAAGTAGAATTTAAAGGCAAAGCTT
ATAAAGTCAAAGAACTTACCGAAAATGTATTTAAAGAAAATCCTATTGATATTGCTTTTTTTAGCGCAGGTGGAAGTGTG
AGTGAAAAATATGCTAAATTTGCAGTAGAATCAGGTGCTATTGTAATTGATAATACAAGTCATTTTAGAATGGAAAAAGA
TGTTCCTTTGGTGGTTCCTGAATGCAATCCTGAGGATATTAAAGATTGGAAAAAAACAGGGATTATTGCTAATCCAAATT
GTTCTACTATACAAATGGTGCAAGTTTTAAAACCTTTAAATGATGCATTTAATTTAAAGCGTGTTGATGTAAGTACCTAT
CAGGCTGCAAGTGGAGCAGGAAAAGAAGGAATGCAAGAATTGGTTGAAGCCATGCAAAGTTTTTTTGCTTTTAAACTTGA
TGAATTTGAACCTCAAACTTTTCCTTATACTTTGGCACTTAATCTTATTCCACAAATTGATGTTTTTATGGATAATGATT
ACACTAAAGAAGAACTTAAAATGGTCAATGAAACTCAAAAAATTTTACATAAAAATTTAGAAGTTTCGGCAACTTGTGTA
AGAGTGCCTGTTTTAAGAAGTCATAGCGAAGCCATTACTATGCATTTTGAAAAAGAAATAGATGTAAAAAAAGCTAAAGA
AATTTTAGAAAAAGCACCAAGTGTTATTGTCATAGATGATCCTAAAAATAAAAAATACCCTATGCCCTTAATGACTAGCG
ATACTAATGAAACTTATGTAGGAAGAATTCGTGCTGATGTGTATGATAAAAAAATACTCCATCTTTGGTGTGTGGCGGAT
CAAATTCGTGTAGGTGCTGCAACAAATGCTGTGCGTATTGCGCAAAAATGGTTAGAATTAAAAAATAAATAA

Upstream 100 bases:

>100_bases
TAAGTGTAGATTATGACAAGGATCAAGCTTCTCAAATTTTAGGTATGGATATAAAAATTTTAAATGAAAAAATTAAAAAA
TATCAAATAAAGGATAAGTA

Downstream 100 bases:

>100_bases
GGAAAAAAATGTTAGAGAAAATATTTGAATCTTTACTTGTTAGAAGTCGTATTGTTACAATTTTACCCGTAATTTTTGGT
TTAATTGGAGCTTTTGTATT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MSKKQKIAIVGATGAVGEELLNVLDELDFPVESILPLASAKSVGSEVEFKGKAYKVKELTENVFKENPIDIAFFSAGGSV
SEKYAKFAVESGAIVIDNTSHFRMEKDVPLVVPECNPEDIKDWKKTGIIANPNCSTIQMVQVLKPLNDAFNLKRVDVSTY
QAASGAGKEGMQELVEAMQSFFAFKLDEFEPQTFPYTLALNLIPQIDVFMDNDYTKEELKMVNETQKILHKNLEVSATCV
RVPVLRSHSEAITMHFEKEIDVKKAKEILEKAPSVIVIDDPKNKKYPMPLMTSDTNETYVGRIRADVYDKKILHLWCVAD
QIRVGAATNAVRIAQKWLELKNK

Sequences:

>Translated_343_residues
MSKKQKIAIVGATGAVGEELLNVLDELDFPVESILPLASAKSVGSEVEFKGKAYKVKELTENVFKENPIDIAFFSAGGSV
SEKYAKFAVESGAIVIDNTSHFRMEKDVPLVVPECNPEDIKDWKKTGIIANPNCSTIQMVQVLKPLNDAFNLKRVDVSTY
QAASGAGKEGMQELVEAMQSFFAFKLDEFEPQTFPYTLALNLIPQIDVFMDNDYTKEELKMVNETQKILHKNLEVSATCV
RVPVLRSHSEAITMHFEKEIDVKKAKEILEKAPSVIVIDDPKNKKYPMPLMTSDTNETYVGRIRADVYDKKILHLWCVAD
QIRVGAATNAVRIAQKWLELKNK
>Mature_342_residues
SKKQKIAIVGATGAVGEELLNVLDELDFPVESILPLASAKSVGSEVEFKGKAYKVKELTENVFKENPIDIAFFSAGGSVS
EKYAKFAVESGAIVIDNTSHFRMEKDVPLVVPECNPEDIKDWKKTGIIANPNCSTIQMVQVLKPLNDAFNLKRVDVSTYQ
AASGAGKEGMQELVEAMQSFFAFKLDEFEPQTFPYTLALNLIPQIDVFMDNDYTKEELKMVNETQKILHKNLEVSATCVR
VPVLRSHSEAITMHFEKEIDVKKAKEILEKAPSVIVIDDPKNKKYPMPLMTSDTNETYVGRIRADVYDKKILHLWCVADQ
IRVGAATNAVRIAQKWLELKNK

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=343, Percent_Identity=33.2361516034985, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI1789841, Length=371, Percent_Identity=29.1105121293801, Blast_Score=112, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6320362, Length=405, Percent_Identity=27.4074074074074, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 38391; Mature: 38259

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKQKIAIVGATGAVGEELLNVLDELDFPVESILPLASAKSVGSEVEFKGKAYKVKELT
CCCCCEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEECCCEEEHHHHH
ENVFKENPIDIAFFSAGGSVSEKYAKFAVESGAIVIDNTSHFRMEKDVPLVVPECNPEDI
HHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEECCCCEEECCCCCEEECCCCHHHH
KDWKKTGIIANPNCSTIQMVQVLKPLNDAFNLKRVDVSTYQAASGAGKEGMQELVEAMQS
HHHHHCCCEECCCCCHHHHHHHHHHHHHHCCEEEEECHHHHCCCCCCHHHHHHHHHHHHH
FFAFKLDEFEPQTFPYTLALNLIPQIDVFMDNDYTKEELKMVNETQKILHKNLEVSATCV
HHHHHHCCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEE
RVPVLRSHSEAITMHFEKEIDVKKAKEILEKAPSVIVIDDPKNKKYPMPLMTSDTNETYV
EEHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCEEECCCCCCEE
GRIRADVYDKKILHLWCVADQIRVGAATNAVRIAQKWLELKNK
EEEEHHHHHHHHEEEEEEHHHHEECCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKKQKIAIVGATGAVGEELLNVLDELDFPVESILPLASAKSVGSEVEFKGKAYKVKELT
CCCCEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEECCCEEEHHHHH
ENVFKENPIDIAFFSAGGSVSEKYAKFAVESGAIVIDNTSHFRMEKDVPLVVPECNPEDI
HHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEECCCCEEECCCCCEEECCCCHHHH
KDWKKTGIIANPNCSTIQMVQVLKPLNDAFNLKRVDVSTYQAASGAGKEGMQELVEAMQS
HHHHHCCCEECCCCCHHHHHHHHHHHHHHCCEEEEECHHHHCCCCCCHHHHHHHHHHHHH
FFAFKLDEFEPQTFPYTLALNLIPQIDVFMDNDYTKEELKMVNETQKILHKNLEVSATCV
HHHHHHCCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEE
RVPVLRSHSEAITMHFEKEIDVKKAKEILEKAPSVIVIDDPKNKKYPMPLMTSDTNETYV
EEHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCEEECCCCCCEE
GRIRADVYDKKILHLWCVADQIRVGAATNAVRIAQKWLELKNK
EEEEHHHHHHHHEEEEEEHHHHEECCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9127485; 10688204 [H]