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The map label for this gene is speA [H]

Identifier: 57237609

GI number: 57237609

Start: 793233

End: 795068

Strand: Reverse

Name: speA [H]

Synonym: CJE0855

Alternate gene names: 57237609

Gene position: 795068-793233 (Counterclockwise)

Preceding gene: 57237610

Following gene: 57237608

Centisome position: 44.72

GC content: 32.9

Gene sequence:

>1836_bases
ATGATGGATTATGGTATTGATATTTGGGGAAATGAAAATTTCATTATCAAAAATGGTAAAGTTTGTATCAATTACGAGAA
AAAACCTGCTATTATTGATATAGTTAAAGAATTAAGAGATGATGGATACAAGGGGCCTTTACTTTTAAGATTTCCTCATC
TTATCCAAAAACAAATTGAAAATATTTACGGAAATTTCAATAAAGCAAGAAAGGAATTTGGCTATAAAGGAGGATTTAAC
GCTGTTTATCCTTTAAAGGTCAATCAATACCCTGGTTTTGTAAAAAATCTTGTAAAACTTGGAAAAGACTATAACTATGG
ACTTGAAGCAGGTTCTAAGGCAGAGCTTTTACTCGCTATGGCTTATAATAACGAAGGCGCACCTATTACCGTAAATGGCT
TTAAAGATAGAGAACTTATCAACATAGGCTTTATTGCAGCTGAAATGGGACATAATATCACTTTAACCATAGAAGGACTT
AATGAACTTGAAGCTATCATAGACATAGCTAAAGAACGCTTTAAACCTAAACCAAATATAGGCTTACGTGTACGTTTGCA
TTCTGCTGGAGTTGGAATTTGGGCAAAAAGCGGTGGGATTAATTCTAAATTTGGACTTACATCCACTGAACTCATAGAAG
CGGTAAATTTACTCAAAGAAAACAAACTTTTAGAACAATTTACCATGATTCACTTTCATCTAGGCTCACAAATTACCGAA
ATTCACCCCTTGAAAAAAGCCTTAAATGAAGCAGGAAATATCTATACAGAACTTAGAAAAATGGGAGCTAAAAATCTAAA
AGCTATTAATCTTGGTGGCGGTTTAGCTGTGGAATACTCACAATTTAAAAATGAAAAAAGTAGAAATTACACCCTAAGAG
AATACGCTAACGATGTAGTTTTTATCCTAAAAAACATAGCCGAACAAAAAAAAGATTTAGAGCCTGATATTTTCATAGAA
AGTGGACGTTTTGTAGCAGCTAATCACGCTGTTTTAATCGCTCCTGTATTAGAACTTTTTTCTCAAGAATACACAGAAAA
CAAACTCATACTTAAAAAACAAAATCCAAAACTTATCGATGAGCTTTATGATCTTTATAAAAGTATAAAACCTTCCAATG
CTTTAGAATACTTGCACGATAGCATAGATCATTTAGAGAGTATTTTAACTCTTTTTGATTTGGGCTATGTGGATTTACAA
GATCGTTCCAATGCTGAAATTTTAACTCATTTGATTACAAAAAAAGCCATCTTGCTTTTAGGCGATAAGCAAAATCCTGC
GGATTTACTTGCCATACAAGATGAAGTGCAAGAAAGGTATTTGGTAAATTTTTCGCTCTTTCAAAGCATGCCTGATTTTT
GGGGTTTAGAACAGAATTTCCCCATCATGCCACTTGATCGCTTAGATGAAGAACCGACACGAAGTGCAAGTATTTGGGAT
ATAACCTGCGATAGCGATGGAGAAATTTCATACTCTAAAGATAAACCTTTATTTTTGCACGATGTAGATGTAGAAAAAGA
AAATTATTTTCTAGGGTTTTTTCTTGTAGGTGCCTATCAAGAAGTACTTGGAATGAAACACAATCTTTTTACTCATCCTA
CTGAAGCTATTATAAGCATCAATGAAAAAGGCTATGAAGTCGAGGGGATTATAGAAGCGCAATCCATACTTGATACCTTA
GAAGATTTAGACTATGATATACACGCTATCATGGATATACTTAATGAACGCATAAGTAATTCTAAGCTTGTAAATGATAA
GCAAAAAAAGCATATTTTAGGCGAACTTTATCTTTTCTTAAATGATAATGGTTATTTAAAAAGCATAGGAGTTTAG

Upstream 100 bases:

>100_bases
GCATGGGAGAAAATGAAGCACAAAATGAAAGTTTGTTTTATAAAAATTTAGCAAAAAAAGAAGAAAAAATGATTAAAATT
TCAGACTTAAAGAAGGTTTT

Downstream 100 bases:

>100_bases
ATGAATTTTTGGGGTATTATAAAAGAAGATTTTTCTCAGCCAAAGGCACAAGATCCAGCTTTTAATTCTTGTATAGAACT
TTTTTTTAATTACCCTGGAG

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 611; Mature: 611

Protein sequence:

>611_residues
MMDYGIDIWGNENFIIKNGKVCINYEKKPAIIDIVKELRDDGYKGPLLLRFPHLIQKQIENIYGNFNKARKEFGYKGGFN
AVYPLKVNQYPGFVKNLVKLGKDYNYGLEAGSKAELLLAMAYNNEGAPITVNGFKDRELINIGFIAAEMGHNITLTIEGL
NELEAIIDIAKERFKPKPNIGLRVRLHSAGVGIWAKSGGINSKFGLTSTELIEAVNLLKENKLLEQFTMIHFHLGSQITE
IHPLKKALNEAGNIYTELRKMGAKNLKAINLGGGLAVEYSQFKNEKSRNYTLREYANDVVFILKNIAEQKKDLEPDIFIE
SGRFVAANHAVLIAPVLELFSQEYTENKLILKKQNPKLIDELYDLYKSIKPSNALEYLHDSIDHLESILTLFDLGYVDLQ
DRSNAEILTHLITKKAILLLGDKQNPADLLAIQDEVQERYLVNFSLFQSMPDFWGLEQNFPIMPLDRLDEEPTRSASIWD
ITCDSDGEISYSKDKPLFLHDVDVEKENYFLGFFLVGAYQEVLGMKHNLFTHPTEAIISINEKGYEVEGIIEAQSILDTL
EDLDYDIHAIMDILNERISNSKLVNDKQKKHILGELYLFLNDNGYLKSIGV

Sequences:

>Translated_611_residues
MMDYGIDIWGNENFIIKNGKVCINYEKKPAIIDIVKELRDDGYKGPLLLRFPHLIQKQIENIYGNFNKARKEFGYKGGFN
AVYPLKVNQYPGFVKNLVKLGKDYNYGLEAGSKAELLLAMAYNNEGAPITVNGFKDRELINIGFIAAEMGHNITLTIEGL
NELEAIIDIAKERFKPKPNIGLRVRLHSAGVGIWAKSGGINSKFGLTSTELIEAVNLLKENKLLEQFTMIHFHLGSQITE
IHPLKKALNEAGNIYTELRKMGAKNLKAINLGGGLAVEYSQFKNEKSRNYTLREYANDVVFILKNIAEQKKDLEPDIFIE
SGRFVAANHAVLIAPVLELFSQEYTENKLILKKQNPKLIDELYDLYKSIKPSNALEYLHDSIDHLESILTLFDLGYVDLQ
DRSNAEILTHLITKKAILLLGDKQNPADLLAIQDEVQERYLVNFSLFQSMPDFWGLEQNFPIMPLDRLDEEPTRSASIWD
ITCDSDGEISYSKDKPLFLHDVDVEKENYFLGFFLVGAYQEVLGMKHNLFTHPTEAIISINEKGYEVEGIIEAQSILDTL
EDLDYDIHAIMDILNERISNSKLVNDKQKKHILGELYLFLNDNGYLKSIGV
>Mature_611_residues
MMDYGIDIWGNENFIIKNGKVCINYEKKPAIIDIVKELRDDGYKGPLLLRFPHLIQKQIENIYGNFNKARKEFGYKGGFN
AVYPLKVNQYPGFVKNLVKLGKDYNYGLEAGSKAELLLAMAYNNEGAPITVNGFKDRELINIGFIAAEMGHNITLTIEGL
NELEAIIDIAKERFKPKPNIGLRVRLHSAGVGIWAKSGGINSKFGLTSTELIEAVNLLKENKLLEQFTMIHFHLGSQITE
IHPLKKALNEAGNIYTELRKMGAKNLKAINLGGGLAVEYSQFKNEKSRNYTLREYANDVVFILKNIAEQKKDLEPDIFIE
SGRFVAANHAVLIAPVLELFSQEYTENKLILKKQNPKLIDELYDLYKSIKPSNALEYLHDSIDHLESILTLFDLGYVDLQ
DRSNAEILTHLITKKAILLLGDKQNPADLLAIQDEVQERYLVNFSLFQSMPDFWGLEQNFPIMPLDRLDEEPTRSASIWD
ITCDSDGEISYSKDKPLFLHDVDVEKENYFLGFFLVGAYQEVLGMKHNLFTHPTEAIISINEKGYEVEGIIEAQSILDTL
EDLDYDIHAIMDILNERISNSKLVNDKQKKHILGELYLFLNDNGYLKSIGV

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=615, Percent_Identity=35.609756097561, Blast_Score=355, Evalue=4e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 69407; Mature: 69407

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00878 ODR_DC_2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDYGIDIWGNENFIIKNGKVCINYEKKPAIIDIVKELRDDGYKGPLLLRFPHLIQKQIE
CCCCCEEEECCCEEEEECCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHH
NIYGNFNKARKEFGYKGGFNAVYPLKVNQYPGFVKNLVKLGKDYNYGLEAGSKAELLLAM
HHHCCHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEE
AYNNEGAPITVNGFKDRELINIGFIAAEMGHNITLTIEGLNELEAIIDIAKERFKPKPNI
EECCCCCEEEEECCCCCEEEEEEEEEHHCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCC
GLRVRLHSAGVGIWAKSGGINSKFGLTSTELIEAVNLLKENKLLEQFTMIHFHLGSQITE
EEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
IHPLKKALNEAGNIYTELRKMGAKNLKAINLGGGLAVEYSQFKNEKSRNYTLREYANDVV
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEHHHHCCCCCCCCCHHHHHHHHH
FILKNIAEQKKDLEPDIFIESGRFVAANHAVLIAPVLELFSQEYTENKLILKKQNPKLID
HHHHHHHHHHHCCCCCEEEECCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHH
ELYDLYKSIKPSNALEYLHDSIDHLESILTLFDLGYVDLQDRSNAEILTHLITKKAILLL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHCEEEEE
GDKQNPADLLAIQDEVQERYLVNFSLFQSMPDFWGLEQNFPIMPLDRLDEEPTRSASIWD
ECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCHHHCCCCCCCCCEEEE
ITCDSDGEISYSKDKPLFLHDVDVEKENYFLGFFLVGAYQEVLGMKHNLFTHPTEAIISI
EEECCCCCEEECCCCCEEEEECCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCHHEEEE
NEKGYEVEGIIEAQSILDTLEDLDYDIHAIMDILNERISNSKLVNDKQKKHILGELYLFL
CCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHEEEEEEEE
NDNGYLKSIGV
CCCCCEEECCC
>Mature Secondary Structure
MMDYGIDIWGNENFIIKNGKVCINYEKKPAIIDIVKELRDDGYKGPLLLRFPHLIQKQIE
CCCCCEEEECCCEEEEECCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHH
NIYGNFNKARKEFGYKGGFNAVYPLKVNQYPGFVKNLVKLGKDYNYGLEAGSKAELLLAM
HHHCCHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEE
AYNNEGAPITVNGFKDRELINIGFIAAEMGHNITLTIEGLNELEAIIDIAKERFKPKPNI
EECCCCCEEEEECCCCCEEEEEEEEEHHCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCC
GLRVRLHSAGVGIWAKSGGINSKFGLTSTELIEAVNLLKENKLLEQFTMIHFHLGSQITE
EEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
IHPLKKALNEAGNIYTELRKMGAKNLKAINLGGGLAVEYSQFKNEKSRNYTLREYANDVV
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEHHHHCCCCCCCCCHHHHHHHHH
FILKNIAEQKKDLEPDIFIESGRFVAANHAVLIAPVLELFSQEYTENKLILKKQNPKLID
HHHHHHHHHHHCCCCCEEEECCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHH
ELYDLYKSIKPSNALEYLHDSIDHLESILTLFDLGYVDLQDRSNAEILTHLITKKAILLL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHCEEEEE
GDKQNPADLLAIQDEVQERYLVNFSLFQSMPDFWGLEQNFPIMPLDRLDEEPTRSASIWD
ECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCHHHCCCCCCCCCEEEE
ITCDSDGEISYSKDKPLFLHDVDVEKENYFLGFFLVGAYQEVLGMKHNLFTHPTEAIISI
EEECCCCCEEECCCCCEEEEECCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCHHEEEE
NEKGYEVEGIIEAQSILDTLEDLDYDIHAIMDILNERISNSKLVNDKQKKHILGELYLFL
CCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHEEEEEEEE
NDNGYLKSIGV
CCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA