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The map label for this gene is tcrA [H]

Identifier: 57237410

GI number: 57237410

Start: 361849

End: 362520

Strand: Reverse

Name: tcrA [H]

Synonym: CJE0404

Alternate gene names: 57237410

Gene position: 362520-361849 (Counterclockwise)

Preceding gene: 57237411

Following gene: 57237409

Centisome position: 20.39

GC content: 31.7

Gene sequence:

>672_bases
ATGAGAATTTTAGTTATAGAAGATGAGATTAGCCTAAATAAAACAATTATAGACAATCTTAATGAATTTGGTTATCAAAC
TGATTCTTCTGAAAATTTTAAAGATGGAGAATACTTTATCGGCATTAGACATTATGATTTAGTTTTAGCAAACTGGACTT
TACCTGATGGAGATGGAGCGGAACTTGTTAACACTATTAAGCATAAATCTCCAAGAACTTCAGTTATGATTATGTCTTCA
AAAACAGACAAAGAAACAGAAATCAAAGCTTTGAAAGCTGGAGCTGATGATTTTGTTACAAAACCTTTAGATTTTGATAT
TCTACTCGCAAGAATTGAAGCAAGACTAAGACTTGGCGGAACCAATGTTATTAAAATTGAAGACTTAGTTATTGATCCAG
ATGAGGAAAAAATTACTTATAAAGATCAAGATATAGAACTTAAAGGAAAACCTTTTGAAGTTTTAACGCACTTAGCAAGA
CATTCGGATCAAATTGTATCCAAAGAACAACTTTTAGATGCCATCTGGGAAGAACCTGAGCTAGTAACTCCAAATGTTAT
CGAAGTAGCTATCAATCAAATTCGTCAAAAAATGGATAAACCATTAAATATATCTACCATAGAAACAGTTCGTCGTAGAG
GATACCGTTTCTGCTTCCCTAAAAAATCTTAA

Upstream 100 bases:

>100_bases
TAAATTGAAAAAAAAATATTAATTTTTTTTTAAAGATATCTAAACATTTACTTAAGCTATGATATAATTCTTTAAATTTT
TCTTAATAAGGATAGAACAA

Downstream 100 bases:

>100_bases
CAATTTTGCACCTTCGGTGCAAAAAATTTATCTTTATTTCTATTTTTATATTTTATTTAAGTTTGGTTATTGTATAAACT
AAAATTATTTTTTAAATTTT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MRILVIEDEISLNKTIIDNLNEFGYQTDSSENFKDGEYFIGIRHYDLVLANWTLPDGDGAELVNTIKHKSPRTSVMIMSS
KTDKETEIKALKAGADDFVTKPLDFDILLARIEARLRLGGTNVIKIEDLVIDPDEEKITYKDQDIELKGKPFEVLTHLAR
HSDQIVSKEQLLDAIWEEPELVTPNVIEVAINQIRQKMDKPLNISTIETVRRRGYRFCFPKKS

Sequences:

>Translated_223_residues
MRILVIEDEISLNKTIIDNLNEFGYQTDSSENFKDGEYFIGIRHYDLVLANWTLPDGDGAELVNTIKHKSPRTSVMIMSS
KTDKETEIKALKAGADDFVTKPLDFDILLARIEARLRLGGTNVIKIEDLVIDPDEEKITYKDQDIELKGKPFEVLTHLAR
HSDQIVSKEQLLDAIWEEPELVTPNVIEVAINQIRQKMDKPLNISTIETVRRRGYRFCFPKKS
>Mature_223_residues
MRILVIEDEISLNKTIIDNLNEFGYQTDSSENFKDGEYFIGIRHYDLVLANWTLPDGDGAELVNTIKHKSPRTSVMIMSS
KTDKETEIKALKAGADDFVTKPLDFDILLARIEARLRLGGTNVIKIEDLVIDPDEEKITYKDQDIELKGKPFEVLTHLAR
HSDQIVSKEQLLDAIWEEPELVTPNVIEVAINQIRQKMDKPLNISTIETVRRRGYRFCFPKKS

Specific function: Member of the three-protein two-component system HK1/HK2/tcrA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=28.2511210762332, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=28.5714285714286, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=26.8181818181818, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=29.4642857142857, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=27.9816513761468, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=25.5605381165919, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=28.8990825688073, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=25.4385964912281, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=27.027027027027, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=24.6636771300448, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI2367329, Length=174, Percent_Identity=26.4367816091954, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788550, Length=117, Percent_Identity=29.0598290598291, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=34.2105263157895, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787229, Length=217, Percent_Identity=23.5023041474654, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25574; Mature: 25574

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVIEDEISLNKTIIDNLNEFGYQTDSSENFKDGEYFIGIRHYDLVLANWTLPDGDGA
CEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEEEEECCCCCCCHH
ELVNTIKHKSPRTSVMIMSSKTDKETEIKALKAGADDFVTKPLDFDILLARIEARLRLGG
HHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHEECC
TNVIKIEDLVIDPDEEKITYKDQDIELKGKPFEVLTHLARHSDQIVSKEQLLDAIWEEPE
CCEEEEEEEEECCCCCEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LVTPNVIEVAINQIRQKMDKPLNISTIETVRRRGYRFCFPKKS
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEECCCCCC
>Mature Secondary Structure
MRILVIEDEISLNKTIIDNLNEFGYQTDSSENFKDGEYFIGIRHYDLVLANWTLPDGDGA
CEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEEEEECCCCCCCHH
ELVNTIKHKSPRTSVMIMSSKTDKETEIKALKAGADDFVTKPLDFDILLARIEARLRLGG
HHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHEECC
TNVIKIEDLVIDPDEEKITYKDQDIELKGKPFEVLTHLARHSDQIVSKEQLLDAIWEEPE
CCEEEEEEEEECCCCCEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LVTPNVIEVAINQIRQKMDKPLNISTIETVRRRGYRFCFPKKS
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]