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The map label for this gene is xseA [H]

Identifier: 57237376

GI number: 57237376

Start: 332124

End: 333287

Strand: Direct

Name: xseA [H]

Synonym: CJE0370

Alternate gene names: 57237376

Gene position: 332124-333287 (Clockwise)

Preceding gene: 57237375

Following gene: 57237377

Centisome position: 18.68

GC content: 28.18

Gene sequence:

>1164_bases
ATGACACCAACAGAATTAAATCTTAAAGCAAAGGCTTTATTAGAAACACATTTTGATGATATAGTTTTAAGTGGAGAAAT
TTCAAAAATTACTTTGCATGGTTCAGGACATTGGTATTTTGATTTAAAAGATGAAAGATCAAGCATTGCTTGTGCTATGT
TTAAAGGAGCTAATTTAAAAGTCGGATTTAAACCAGCTGTGGGGAATTTTTTAGAGCTTTGTGGAAGTGTAAGTTTATAT
CCTGAAAGTGGTCGTTATCAATTTATCGCTACTAGTATGAAAAAAGCAGGTTTTGGGGATTTGGAAGCACAGTTTTTGGC
TTTAAAAGAGCGTTTGCAAAAAGAAGGACTTTTTGATCCACGCTTTAAAAAATCTTTGCCAAAATTTCCTAAAAAAGTAG
GCATTATCACTTCAAAAACTTCTGCTGCTTTGCAAGATATGTTAAAACTTATTCACCAAAAAGAATATTTTTTGGCAAAA
ATTTATATTTTTGATGCTTTAACTCAAGGAAATAATGCTCCTTTTTCTCTTATACGAGCTTTAAAAAAAGCCGATGATAT
GGATTTAGATGTTCTTATTATAGCACGTGGTGGAGGAAGCAGAGAAGATCTTTTTTGTTTTAATGATGAAAATTTAGCAA
GAGAGATTTTTAAAGCAAAAACTCCTATTATTTCAGCCATAGGACATGAGATTGATTATGTTATTAGTGATTTTGTTGCA
GATTTTAGAGCTCCAACGCCTTCAGCTGCTATAGATACTTTGTTTTATTCTAAGTTGGATATAGAGCAAAGTTTGGATTT
AATGGAAGAAAAATTAATGCAACTTTGGAATTATAAAATACAAAATTATGAAAATTTGCTTTTAAATTTAAGCAAATTTT
TCAAATTTAATTCTTTGCCAAAAATAATAGATGAAAAAATAAAACAAAGCCATAATATAGAAAAGCAATTAAATCATCTA
TTGGCAAATCAAATGCGTTATAATGAATTAAAATTAGATAAATTGCAAAATGCTTATTTGCAACATGAGAATTTTTTTAA
TAAAAGCAAAAAGTTTATTTGTATCAGAAAAAATGGTAAAATAGCAAATTTAGAAGATCTTAAGAGTGATGATATCGTTA
TTTTAAGTTCTCAAACTTCTCAAAAAGAAGCAAAAATTTTATAA

Upstream 100 bases:

>100_bases
AGGAAGAGTTCATCTTAGAACTTAAAAATGCTGGTTTTGAAATACTTGATTATAAAAGTTTTAGCTTTGGCGTGAGTTCA
ATGTTTATAGCAAAAAAACT

Downstream 100 bases:

>100_bases
GGATAGATTATGAGAAAAATCAATTTCAGTGCAGGGCCATCGACTTTACCTTTAGAAATTTTAGAGCAAGCTCAAAAAGA
ACTCTGTGATTATCAGGGTA

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MTPTELNLKAKALLETHFDDIVLSGEISKITLHGSGHWYFDLKDERSSIACAMFKGANLKVGFKPAVGNFLELCGSVSLY
PESGRYQFIATSMKKAGFGDLEAQFLALKERLQKEGLFDPRFKKSLPKFPKKVGIITSKTSAALQDMLKLIHQKEYFLAK
IYIFDALTQGNNAPFSLIRALKKADDMDLDVLIIARGGGSREDLFCFNDENLAREIFKAKTPIISAIGHEIDYVISDFVA
DFRAPTPSAAIDTLFYSKLDIEQSLDLMEEKLMQLWNYKIQNYENLLLNLSKFFKFNSLPKIIDEKIKQSHNIEKQLNHL
LANQMRYNELKLDKLQNAYLQHENFFNKSKKFICIRKNGKIANLEDLKSDDIVILSSQTSQKEAKIL

Sequences:

>Translated_387_residues
MTPTELNLKAKALLETHFDDIVLSGEISKITLHGSGHWYFDLKDERSSIACAMFKGANLKVGFKPAVGNFLELCGSVSLY
PESGRYQFIATSMKKAGFGDLEAQFLALKERLQKEGLFDPRFKKSLPKFPKKVGIITSKTSAALQDMLKLIHQKEYFLAK
IYIFDALTQGNNAPFSLIRALKKADDMDLDVLIIARGGGSREDLFCFNDENLAREIFKAKTPIISAIGHEIDYVISDFVA
DFRAPTPSAAIDTLFYSKLDIEQSLDLMEEKLMQLWNYKIQNYENLLLNLSKFFKFNSLPKIIDEKIKQSHNIEKQLNHL
LANQMRYNELKLDKLQNAYLQHENFFNKSKKFICIRKNGKIANLEDLKSDDIVILSSQTSQKEAKIL
>Mature_386_residues
TPTELNLKAKALLETHFDDIVLSGEISKITLHGSGHWYFDLKDERSSIACAMFKGANLKVGFKPAVGNFLELCGSVSLYP
ESGRYQFIATSMKKAGFGDLEAQFLALKERLQKEGLFDPRFKKSLPKFPKKVGIITSKTSAALQDMLKLIHQKEYFLAKI
YIFDALTQGNNAPFSLIRALKKADDMDLDVLIIARGGGSREDLFCFNDENLAREIFKAKTPIISAIGHEIDYVISDFVAD
FRAPTPSAAIDTLFYSKLDIEQSLDLMEEKLMQLWNYKIQNYENLLLNLSKFFKFNSLPKIIDEKIKQSHNIEKQLNHLL
ANQMRYNELKLDKLQNAYLQHENFFNKSKKFICIRKNGKIANLEDLKSDDIVILSSQTSQKEAKIL

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=282, Percent_Identity=42.9078014184397, Blast_Score=251, Evalue=8e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 44116; Mature: 43984

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPTELNLKAKALLETHFDDIVLSGEISKITLHGSGHWYFDLKDERSSIACAMFKGANLK
CCCCCCCHHHHHHHHHHHCCEEEECCEEEEEEECCCEEEEEECCCCCCEEEEEECCCCEE
VGFKPAVGNFLELCGSVSLYPESGRYQFIATSMKKAGFGDLEAQFLALKERLQKEGLFDP
EECCHHHHHHHHHHCCCEECCCCCCEEEEEEHHHHCCCCCHHHHHHHHHHHHHHCCCCCC
RFKKSLPKFPKKVGIITSKTSAALQDMLKLIHQKEYFLAKIYIFDALTQGNNAPFSLIRA
HHHHHCCCCHHHHCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LKKADDMDLDVLIIARGGGSREDLFCFNDENLAREIFKAKTPIISAIGHEIDYVISDFVA
HHHCCCCCCEEEEEECCCCCCCCEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
DFRAPTPSAAIDTLFYSKLDIEQSLDLMEEKLMQLWNYKIQNYENLLLNLSKFFKFNSLP
HHCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
KIIDEKIKQSHNIEKQLNHLLANQMRYNELKLDKLQNAYLQHENFFNKSKKFICIRKNGK
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
IANLEDLKSDDIVILSSQTSQKEAKIL
CCCHHHCCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
TPTELNLKAKALLETHFDDIVLSGEISKITLHGSGHWYFDLKDERSSIACAMFKGANLK
CCCCCCHHHHHHHHHHHCCEEEECCEEEEEEECCCEEEEEECCCCCCEEEEEECCCCEE
VGFKPAVGNFLELCGSVSLYPESGRYQFIATSMKKAGFGDLEAQFLALKERLQKEGLFDP
EECCHHHHHHHHHHCCCEECCCCCCEEEEEEHHHHCCCCCHHHHHHHHHHHHHHCCCCCC
RFKKSLPKFPKKVGIITSKTSAALQDMLKLIHQKEYFLAKIYIFDALTQGNNAPFSLIRA
HHHHHCCCCHHHHCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LKKADDMDLDVLIIARGGGSREDLFCFNDENLAREIFKAKTPIISAIGHEIDYVISDFVA
HHHCCCCCCEEEEEECCCCCCCCEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
DFRAPTPSAAIDTLFYSKLDIEQSLDLMEEKLMQLWNYKIQNYENLLLNLSKFFKFNSLP
HHCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
KIIDEKIKQSHNIEKQLNHLLANQMRYNELKLDKLQNAYLQHENFFNKSKKFICIRKNGK
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
IANLEDLKSDDIVILSSQTSQKEAKIL
CCCHHHCCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA