Click here to switch to the map view.

The map label for this gene is ykkC [H]

Identifier: 57237361

GI number: 57237361

Start: 317465

End: 317803

Strand: Reverse

Name: ykkC [H]

Synonym: CJE0355

Alternate gene names: 57237361

Gene position: 317803-317465 (Counterclockwise)

Preceding gene: 57237379

Following gene: 57237360

Centisome position: 17.88

GC content: 30.38

Gene sequence:

>339_bases
GTGAATGAAAAATTCAATATCAATATAGCTTGGTTTTTAATAATCTTAGGCGGGATTATAGAATGTTTTTGGGTAAGTGG
ACTTAAGTATTCTACAGAAATTTGGCACTATATTTTAACAGCCATTGGGGTTTGTATTTCTTTTACTTGTTTTTTAAAAG
CTTGTGAAAGACTTGAAGTAAGCATTACTTATAGTGTTTTTGTAGGCATTGGCACTATAGGAGTGGTTTTAAATGAAATG
TTTATTTTTAATGAGGCTGTTTCTATAATTAAACTTGTGCTTATAGCGATTTTACTTTTAAGCATTATAGCCCTTAAATG
GGTAAGCAAGGAAGCTTAG

Upstream 100 bases:

>100_bases
TTATATCTAATTTTGGCTTATGGAAAAGTAAATTTATAGCTTCTTTTAATTTCTTTAAGATATAATTTGTTTTATAAATT
ATGTTAATTTAAGGCTTCAT

Downstream 100 bases:

>100_bases
TTATGGAATGGTTTTATTTGTTTTTAGCTACTGCTTGTGAAATTTTTGGTGTGGTGATCATGAAAGAACTTGTAAACACT
AAAAACAAGCTTTACTTTTT

Product: SMR family multidrug efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 112; Mature: 112

Protein sequence:

>112_residues
MNEKFNINIAWFLIILGGIIECFWVSGLKYSTEIWHYILTAIGVCISFTCFLKACERLEVSITYSVFVGIGTIGVVLNEM
FIFNEAVSIIKLVLIAILLLSIIALKWVSKEA

Sequences:

>Translated_112_residues
MNEKFNINIAWFLIILGGIIECFWVSGLKYSTEIWHYILTAIGVCISFTCFLKACERLEVSITYSVFVGIGTIGVVLNEM
FIFNEAVSIIKLVLIAILLLSIIALKWVSKEA
>Mature_112_residues
MNEKFNINIAWFLIILGGIIECFWVSGLKYSTEIWHYILTAIGVCISFTCFLKACERLEVSITYSVFVGIGTIGVVLNEM
FIFNEAVSIIKLVLIAILLLSIIALKWVSKEA

Specific function: Part of a multidrug efflux pump. Confers resistance to a broad range of toxic compounds such as cationic dyes, neutral and anionic antimicrobials [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. YkkC/ykkD (TC 2.A.7.1.5) subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 12595; Mature: 12595

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEKFNINIAWFLIILGGIIECFWVSGLKYSTEIWHYILTAIGVCISFTCFLKACERLEV
CCCEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SITYSVFVGIGTIGVVLNEMFIFNEAVSIIKLVLIAILLLSIIALKWVSKEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNEKFNINIAWFLIILGGIIECFWVSGLKYSTEIWHYILTAIGVCISFTCFLKACERLEV
CCCEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SITYSVFVGIGTIGVVLNEMFIFNEAVSIIKLVLIAILLLSIIALKWVSKEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA