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The map label for this gene is ykkD [H]

Identifier: 57237360

GI number: 57237360

Start: 317148

End: 317462

Strand: Reverse

Name: ykkD [H]

Synonym: CJE0354

Alternate gene names: 57237360

Gene position: 317462-317148 (Counterclockwise)

Preceding gene: 57237361

Following gene: 57237359

Centisome position: 17.86

GC content: 30.79

Gene sequence:

>315_bases
ATGGAATGGTTTTATTTGTTTTTAGCTACTGCTTGTGAAATTTTTGGTGTGGTGATCATGAAAGAACTTGTAAACACTAA
AAACAAGCTTTACTTTTTAGCTTTGATAGTGTGTTTTGGATTTTCTTTTACTTTTTTAAGCTTAAGTATGCAAAATATCG
CTATGAGCGTTGCTTATGCTATATGGACAGGAGCTGGAACCGCTGGTGGGGTAATGATAGGAGTGCTTTTTTATAAAGAA
AGTAAAAGTTTTTTAAAACTTTTTTTAATCACTGTGATTATTGCTTGTACAGTAGGTTTAAAATTTCTTTCTTAA

Upstream 100 bases:

>100_bases
TTATTTTTAATGAGGCTGTTTCTATAATTAAACTTGTGCTTATAGCGATTTTACTTTTAAGCATTATAGCCCTTAAATGG
GTAAGCAAGGAAGCTTAGTT

Downstream 100 bases:

>100_bases
GGATTTTTTGTGCAAATTTATGTGAGTGGAATACATACTGATGTAGGAAAAACACATTTTAGTGCAGCTTTTTGTGCGAA
TTTTAACTATGATTATTTTA

Product: SMR family multidrug efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 104; Mature: 104

Protein sequence:

>104_residues
MEWFYLFLATACEIFGVVIMKELVNTKNKLYFLALIVCFGFSFTFLSLSMQNIAMSVAYAIWTGAGTAGGVMIGVLFYKE
SKSFLKLFLITVIIACTVGLKFLS

Sequences:

>Translated_104_residues
MEWFYLFLATACEIFGVVIMKELVNTKNKLYFLALIVCFGFSFTFLSLSMQNIAMSVAYAIWTGAGTAGGVMIGVLFYKE
SKSFLKLFLITVIIACTVGLKFLS
>Mature_104_residues
MEWFYLFLATACEIFGVVIMKELVNTKNKLYFLALIVCFGFSFTFLSLSMQNIAMSVAYAIWTGAGTAGGVMIGVLFYKE
SKSFLKLFLITVIIACTVGLKFLS

Specific function: Part of a multidrug efflux pump. Confers resistance to a broad range of toxic compounds such as cationic dyes, neutral and anionic antimicrobials [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. YkkC/ykkD (TC 2.A.7.1.5) subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11567; Mature: 11567

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWFYLFLATACEIFGVVIMKELVNTKNKLYFLALIVCFGFSFTFLSLSMQNIAMSVAYA
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IWTGAGTAGGVMIGVLFYKESKSFLKLFLITVIIACTVGLKFLS
HHCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEWFYLFLATACEIFGVVIMKELVNTKNKLYFLALIVCFGFSFTFLSLSMQNIAMSVAYA
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IWTGAGTAGGVMIGVLFYKESKSFLKLFLITVIIACTVGLKFLS
HHCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8682784; 9384377 [H]