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The map label for this gene is panC [H]

Identifier: 57237348

GI number: 57237348

Start: 307248

End: 308096

Strand: Reverse

Name: panC [H]

Synonym: CJE0342

Alternate gene names: 57237348

Gene position: 308096-307248 (Counterclockwise)

Preceding gene: 57237349

Following gene: 57237347

Centisome position: 17.33

GC content: 32.51

Gene sequence:

>849_bases
ATGGAAGTCATTACTTCTATCAAAGAAGCAAAACAAACTGTAAAAAATTGGAAATCACATAACCTTAGCATAGGCTATGT
TCCAACCATGGGCTTTTTACACGATGGGCATTTAAGTTTAGTCAAAAATGCCAAAACACAAGATAAAGTCATAGTAAGTA
TCTTTGTAAATCCTATGCAATTTGGCCCTAACGAAGATTTTTCTAGTTATCCAAGAGATTTAGAACGCGACATTAAAATG
TGTCAAGATAATGGCGTTGATATGGTTTTTATCCCCGATGCAGCTCAAATGTATCTTAAGAATTTTAGCACCTATGTGGA
TATGAACACGATCACGGATAAGCTTTGTGGAGCTAAAAGACTGGGGCATTTTAGAGGCGTTTGCACAGTTTTGGCTAAAT
TTTTTAATATCCTAAACCCTGATATAGTCTATATGGGGCAAAAAGACGCGCAGCAATGCGTAGTCGTTAGACATATGGTT
GATGATTTAAATTTTGATTTAAAAATTCAAATTTGTCCTATCATTAGAGAAGAAGATGGCTTAGCTAAAAGCTCTAGAAA
TGTATATCTTAGCGAAGAAGAAAGAAAAGCGTCACTAGCTATATCTCAAAGCATTTTTTTAGCTGAAAAATTAGTCCAAG
AAGGAGAAAAAGATACTTCCAAAATTATCCAAGCTATGAAAGATATTTTAGAAAAAGAAAAATTAATCAAAATCGATTAT
ATAGAATTAGTTGATTTTAACACTATGGAAAATATTAAAAATATCGCCGATAATGTTTTAGGAGCAGTGGCTGCTTTTGT
TGGAAAAACAAGACTCATTGATAATTTTTTAGTACAAGGATTAAAATGA

Upstream 100 bases:

>100_bases
TATAGAGATGAAGTTAAAAGCGGTATTTTTCCTTCCGAAGAGCACAGCTTTGATTATTTAGATGATGAATTATTAGATAA
ATTATACTAAGGATACAAAT

Downstream 100 bases:

>100_bases
ACATTACTTTACTCAAATCAAAAATACACCGTGCAAACGTAACAGAAGCTAGGCTTGATTATGTAGGAAGCATAAGCATA
GATGAAAAATTATTGCAAGC

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MEVITSIKEAKQTVKNWKSHNLSIGYVPTMGFLHDGHLSLVKNAKTQDKVIVSIFVNPMQFGPNEDFSSYPRDLERDIKM
CQDNGVDMVFIPDAAQMYLKNFSTYVDMNTITDKLCGAKRLGHFRGVCTVLAKFFNILNPDIVYMGQKDAQQCVVVRHMV
DDLNFDLKIQICPIIREEDGLAKSSRNVYLSEEERKASLAISQSIFLAEKLVQEGEKDTSKIIQAMKDILEKEKLIKIDY
IELVDFNTMENIKNIADNVLGAVAAFVGKTRLIDNFLVQGLK

Sequences:

>Translated_282_residues
MEVITSIKEAKQTVKNWKSHNLSIGYVPTMGFLHDGHLSLVKNAKTQDKVIVSIFVNPMQFGPNEDFSSYPRDLERDIKM
CQDNGVDMVFIPDAAQMYLKNFSTYVDMNTITDKLCGAKRLGHFRGVCTVLAKFFNILNPDIVYMGQKDAQQCVVVRHMV
DDLNFDLKIQICPIIREEDGLAKSSRNVYLSEEERKASLAISQSIFLAEKLVQEGEKDTSKIIQAMKDILEKEKLIKIDY
IELVDFNTMENIKNIADNVLGAVAAFVGKTRLIDNFLVQGLK
>Mature_282_residues
MEVITSIKEAKQTVKNWKSHNLSIGYVPTMGFLHDGHLSLVKNAKTQDKVIVSIFVNPMQFGPNEDFSSYPRDLERDIKM
CQDNGVDMVFIPDAAQMYLKNFSTYVDMNTITDKLCGAKRLGHFRGVCTVLAKFFNILNPDIVYMGQKDAQQCVVVRHMV
DDLNFDLKIQICPIIREEDGLAKSSRNVYLSEEERKASLAISQSIFLAEKLVQEGEKDTSKIIQAMKDILEKEKLIKIDY
IELVDFNTMENIKNIADNVLGAVAAFVGKTRLIDNFLVQGLK

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=283, Percent_Identity=41.3427561837456, Blast_Score=212, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6322046, Length=313, Percent_Identity=35.7827476038339, Blast_Score=182, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 31951; Mature: 31951

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVITSIKEAKQTVKNWKSHNLSIGYVPTMGFLHDGHLSLVKNAKTQDKVIVSIFVNPMQ
CHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEECCCHHHHHCCCCCCEEEEEEEECHHH
FGPNEDFSSYPRDLERDIKMCQDNGVDMVFIPDAAQMYLKNFSTYVDMNTITDKLCGAKR
CCCCCCHHHCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHEEHHHHHHHHHHHHH
LGHFRGVCTVLAKFFNILNPDIVYMGQKDAQQCVVVRHMVDDLNFDLKIQICPIIREEDG
HHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCC
LAKSSRNVYLSEEERKASLAISQSIFLAEKLVQEGEKDTSKIIQAMKDILEKEKLIKIDY
CCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEEEE
IELVDFNTMENIKNIADNVLGAVAAFVGKTRLIDNFLVQGLK
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEVITSIKEAKQTVKNWKSHNLSIGYVPTMGFLHDGHLSLVKNAKTQDKVIVSIFVNPMQ
CHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEECCCHHHHHCCCCCCEEEEEEEECHHH
FGPNEDFSSYPRDLERDIKMCQDNGVDMVFIPDAAQMYLKNFSTYVDMNTITDKLCGAKR
CCCCCCHHHCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHEEHHHHHHHHHHHHH
LGHFRGVCTVLAKFFNILNPDIVYMGQKDAQQCVVVRHMVDDLNFDLKIQICPIIREEDG
HHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCC
LAKSSRNVYLSEEERKASLAISQSIFLAEKLVQEGEKDTSKIIQAMKDILEKEKLIKIDY
CCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEEEE
IELVDFNTMENIKNIADNVLGAVAAFVGKTRLIDNFLVQGLK
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA