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The map label for this gene is clpX [H]

Identifier: 57237331

GI number: 57237331

Start: 288127

End: 289350

Strand: Direct

Name: clpX [H]

Synonym: CJE0324

Alternate gene names: 57237331

Gene position: 288127-289350 (Clockwise)

Preceding gene: 57237330

Following gene: 57237332

Centisome position: 16.21

GC content: 31.29

Gene sequence:

>1224_bases
ATGCCTAGAAAATGTAGTTTTTGCAATGAAGTGGAGAATCCACAAAGAAGAATTTTAGCAAATGAAAATGATGATGCTTT
TATTTGTGAATATTGCGTTGAAGGTGCTTATAGTATTATTTATGGAGAAGAAAAAGAATTTAAAGAACCTAAACAAAGTT
ATAATACAGAATTTAAAGATATCACTCCAAAAGAATTAAAAGCTTATTTAGATCGTTATGTCATAGGACAAGATAGAGCT
AAAAAAGTTTTTAGTGTTGGAGTATACAATCATTATAAAAGACTTTTTAAAGCTGAACTTCAAGATGATGATACAGAGCT
TTTTAAGTCAAATATTTTACTTGTTGGGCCAACAGGAAGTGGAAAAACTTTATTGGCGCAAACTTTAGCTAAATTTTTAG
ATGTACCTATAGCAATTTGTGATGCAACTTCTTTAACTGAAGCAGGATATGTAGGTGAGGATGTAGAAAATATTTTAACA
CGTCTTTTACAAGCTGCAGATGGAGATGTGCAAAGAGCTCAAAAAGGTATAGTTTTTATTGATGAGATTGATAAAATTGC
CAGAATGAGTGAAAATCGTTCTATTACTCGTGATGTAAGTGGAGAGGGTGTGCAACAAGCTTTACTTAAGATTATCGAAG
GAAGTTTGGTAAATATTCCACCAAAGGGGGGGAGAAAACATCCAAATCAAGAGTTTATACAAATTGACACTTCAAATATT
TTATTTGTTTGTGGTGGAGCTTTTGATGGTTTGGAAACTATCTTAAAAAGAAAACTTGGAGATAAAGTTGTAGGTTTTTT
TGATGATGCAAAAGAAGAAAATAAAGCTTTACTTGAGAAAATTGAACCTGATGATTTGGTGCATTTTGGTTTGATTCCTG
AGCTTATAGGTCGTTTGCATGTGATTGCATCTTTAAATGAGCTTAATGAAGAAGATATGGTAAGAATTTTAACTGAACCT
AAAAATGCCATTATTAAGCAATATCAAAAGCTTTTTGCTATTGATGGGGTAAATTTAAAATTTGAAGAAGATGCTCTAAG
AGCTATCGCACAGCTTGCATTGGAGAGAAAAACAGGGGCTAGGGGGCTTAGAAGTATTATAGAAGAAATGATGGTAGATT
TAATGTTTGAGTTACCAGAGTATAAAAACTATGATATTGTAATAACCAAAGAAGTTGTTAAAGACAATGCAAAGGCATTA
TTAATAAAAAGAAAAATAAGTTAA

Upstream 100 bases:

>100_bases
AAAAATTTGCTTGAAAATCAAGAAAGTGAAAATGTTAAAAAAATGTGCCATTTTATATTAGAAACAAAGCGTGGAATTCC
TGTCTATAGGGGTAAAAATA

Downstream 100 bases:

>100_bases
AAGGATAGAAATGATATTAGATCAACTTATAGGATTTTTTTCTAGTGATATGGGGATTGATTTAGGAACAGCTAATACGC
TAGTTTTGGTAAAAGATAAG

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MPRKCSFCNEVENPQRRILANENDDAFICEYCVEGAYSIIYGEEKEFKEPKQSYNTEFKDITPKELKAYLDRYVIGQDRA
KKVFSVGVYNHYKRLFKAELQDDDTELFKSNILLVGPTGSGKTLLAQTLAKFLDVPIAICDATSLTEAGYVGEDVENILT
RLLQAADGDVQRAQKGIVFIDEIDKIARMSENRSITRDVSGEGVQQALLKIIEGSLVNIPPKGGRKHPNQEFIQIDTSNI
LFVCGGAFDGLETILKRKLGDKVVGFFDDAKEENKALLEKIEPDDLVHFGLIPELIGRLHVIASLNELNEEDMVRILTEP
KNAIIKQYQKLFAIDGVNLKFEEDALRAIAQLALERKTGARGLRSIIEEMMVDLMFELPEYKNYDIVITKEVVKDNAKAL
LIKRKIS

Sequences:

>Translated_407_residues
MPRKCSFCNEVENPQRRILANENDDAFICEYCVEGAYSIIYGEEKEFKEPKQSYNTEFKDITPKELKAYLDRYVIGQDRA
KKVFSVGVYNHYKRLFKAELQDDDTELFKSNILLVGPTGSGKTLLAQTLAKFLDVPIAICDATSLTEAGYVGEDVENILT
RLLQAADGDVQRAQKGIVFIDEIDKIARMSENRSITRDVSGEGVQQALLKIIEGSLVNIPPKGGRKHPNQEFIQIDTSNI
LFVCGGAFDGLETILKRKLGDKVVGFFDDAKEENKALLEKIEPDDLVHFGLIPELIGRLHVIASLNELNEEDMVRILTEP
KNAIIKQYQKLFAIDGVNLKFEEDALRAIAQLALERKTGARGLRSIIEEMMVDLMFELPEYKNYDIVITKEVVKDNAKAL
LIKRKIS
>Mature_406_residues
PRKCSFCNEVENPQRRILANENDDAFICEYCVEGAYSIIYGEEKEFKEPKQSYNTEFKDITPKELKAYLDRYVIGQDRAK
KVFSVGVYNHYKRLFKAELQDDDTELFKSNILLVGPTGSGKTLLAQTLAKFLDVPIAICDATSLTEAGYVGEDVENILTR
LLQAADGDVQRAQKGIVFIDEIDKIARMSENRSITRDVSGEGVQQALLKIIEGSLVNIPPKGGRKHPNQEFIQIDTSNIL
FVCGGAFDGLETILKRKLGDKVVGFFDDAKEENKALLEKIEPDDLVHFGLIPELIGRLHVIASLNELNEEDMVRILTEPK
NAIIKQYQKLFAIDGVNLKFEEDALRAIAQLALERKTGARGLRSIIEEMMVDLMFELPEYKNYDIVITKEVVKDNAKALL
IKRKIS

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=321, Percent_Identity=52.6479750778816, Blast_Score=318, Evalue=8e-87,
Organism=Escherichia coli, GI1786642, Length=408, Percent_Identity=54.9019607843137, Blast_Score=436, Evalue=1e-123,
Organism=Escherichia coli, GI1790366, Length=239, Percent_Identity=32.6359832635983, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71982908, Length=310, Percent_Identity=47.0967741935484, Blast_Score=288, Evalue=4e-78,
Organism=Caenorhabditis elegans, GI71982905, Length=310, Percent_Identity=47.0967741935484, Blast_Score=288, Evalue=5e-78,
Organism=Caenorhabditis elegans, GI71988663, Length=408, Percent_Identity=37.5, Blast_Score=253, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI71988660, Length=253, Percent_Identity=40.3162055335968, Blast_Score=180, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6319704, Length=407, Percent_Identity=43.7346437346437, Blast_Score=276, Evalue=5e-75,
Organism=Drosophila melanogaster, GI24648291, Length=316, Percent_Identity=49.0506329113924, Blast_Score=312, Evalue=2e-85,
Organism=Drosophila melanogaster, GI24648289, Length=316, Percent_Identity=49.0506329113924, Blast_Score=312, Evalue=3e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR002078
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 45928; Mature: 45797

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00676 SIGMA54_INTERACT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRKCSFCNEVENPQRRILANENDDAFICEYCVEGAYSIIYGEEKEFKEPKQSYNTEFKD
CCCCCCCHHHCCCCHHHCCCCCCCCHHHHHHHHHCCCEEEECCHHHHCCHHHHHCCCCCC
ITPKELKAYLDRYVIGQDRAKKVFSVGVYNHYKRLFKAELQDDDTELFKSNILLVGPTGS
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCEEEEECCCC
GKTLLAQTLAKFLDVPIAICDATSLTEAGYVGEDVENILTRLLQAADGDVQRAQKGIVFI
CHHHHHHHHHHHHCCCEEEECCCHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCEEH
DEIDKIARMSENRSITRDVSGEGVQQALLKIIEGSLVNIPPKGGRKHPNQEFIQIDTSNI
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCEEEEECCCE
LFVCGGAFDGLETILKRKLGDKVVGFFDDAKEENKALLEKIEPDDLVHFGLIPELIGRLH
EEEECCCHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VIASLNELNEEDMVRILTEPKNAIIKQYQKLFAIDGVNLKFEEDALRAIAQLALERKTGA
HHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCH
RGLRSIIEEMMVDLMFELPEYKNYDIVITKEVVKDNAKALLIKRKIS
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHCCCCEEEEEECCC
>Mature Secondary Structure 
PRKCSFCNEVENPQRRILANENDDAFICEYCVEGAYSIIYGEEKEFKEPKQSYNTEFKD
CCCCCCHHHCCCCHHHCCCCCCCCHHHHHHHHHCCCEEEECCHHHHCCHHHHHCCCCCC
ITPKELKAYLDRYVIGQDRAKKVFSVGVYNHYKRLFKAELQDDDTELFKSNILLVGPTGS
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCEEEEECCCC
GKTLLAQTLAKFLDVPIAICDATSLTEAGYVGEDVENILTRLLQAADGDVQRAQKGIVFI
CHHHHHHHHHHHHCCCEEEECCCHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCEEH
DEIDKIARMSENRSITRDVSGEGVQQALLKIIEGSLVNIPPKGGRKHPNQEFIQIDTSNI
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCEEEEECCCE
LFVCGGAFDGLETILKRKLGDKVVGFFDDAKEENKALLEKIEPDDLVHFGLIPELIGRLH
EEEECCCHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VIASLNELNEEDMVRILTEPKNAIIKQYQKLFAIDGVNLKFEEDALRAIAQLALERKTGA
HHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCH
RGLRSIIEEMMVDLMFELPEYKNYDIVITKEVVKDNAKALLIKRKIS
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]