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The map label for this gene is cynT [H]

Identifier: 57237297

GI number: 57237297

Start: 254639

End: 255274

Strand: Direct

Name: cynT [H]

Synonym: CJE0288

Alternate gene names: 57237297

Gene position: 254639-255274 (Clockwise)

Preceding gene: 57237289

Following gene: 57237298

Centisome position: 14.32

GC content: 31.45

Gene sequence:

>636_bases
ATGGAAAATCTTATTAGTGGTGCGATTAAGTTTATGCAAGAAGACTTTAAGGAGCATGAAGAACTTTTTGAAAGTCTAAA
AAATAAGCAAAATCCCCATACTCTTTTTATAGGTTGTTCTGATTCTAGAGTAATTCCAAATTTGATCACCAATACGGGTC
CAGGTGAGCTTTTTGTAATACGAAATATTGCAAATATAGTTCCACCTTATCGCATTGGGGAAGATTACTTAGCGACAACT
TCAGCAATAGAGTATGCTTTAAATTCATTGCATATTAAAAATATCGTCGTTTGTGGCCATAGTAATTGTGGAGGTTGCAA
TGCTCTTTATTATTCTGATGAAGAGTTAAATAAAATTCCTAATGTGAAAAAATGGCTTACTATGTTAGATCCGATAAAAA
AAGATGTAATGATTTTTGCAAGAGACGATTTGGCTATGCGCTCATGGCTTACAGAAAAATTAAATTTAGTAAATTCTTTG
CAAAATATACTTACTTATCCAGGCGTGCAAGAAGCTTTAGATGAAGGAAAAATAGAAGTACATGCTTGGTATTATATTAT
AGAGACAGGTGAAATTTATGAGTATGATTTTAAAGCAAAAATTTTTACTTTAATACAGGATAGGAAAGTTCAATGA

Upstream 100 bases:

>100_bases
GACTAAATAAAAAGTTAATTTATATAATATCTTTATGATTAAATGAAATCTTTGCTGAAATTTTGTTATAATTTCAAGAT
TTTAGTTTCAGGTTGGTTTT

Downstream 100 bases:

>100_bases
AGAAAATTATTTTTAGTTTATGTTTTTTTATTTTATACCTTGGAGCACAAGAATTTAAATTTATTGATGCGAATATTAGT
AAAGAGGATGAAGGAATTTA

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MENLISGAIKFMQEDFKEHEELFESLKNKQNPHTLFIGCSDSRVIPNLITNTGPGELFVIRNIANIVPPYRIGEDYLATT
SAIEYALNSLHIKNIVVCGHSNCGGCNALYYSDEELNKIPNVKKWLTMLDPIKKDVMIFARDDLAMRSWLTEKLNLVNSL
QNILTYPGVQEALDEGKIEVHAWYYIIETGEIYEYDFKAKIFTLIQDRKVQ

Sequences:

>Translated_211_residues
MENLISGAIKFMQEDFKEHEELFESLKNKQNPHTLFIGCSDSRVIPNLITNTGPGELFVIRNIANIVPPYRIGEDYLATT
SAIEYALNSLHIKNIVVCGHSNCGGCNALYYSDEELNKIPNVKKWLTMLDPIKKDVMIFARDDLAMRSWLTEKLNLVNSL
QNILTYPGVQEALDEGKIEVHAWYYIIETGEIYEYDFKAKIFTLIQDRKVQ
>Mature_211_residues
MENLISGAIKFMQEDFKEHEELFESLKNKQNPHTLFIGCSDSRVIPNLITNTGPGELFVIRNIANIVPPYRIGEDYLATT
SAIEYALNSLHIKNIVVCGHSNCGGCNALYYSDEELNKIPNVKKWLTMLDPIKKDVMIFARDDLAMRSWLTEKLNLVNSL
QNILTYPGVQEALDEGKIEVHAWYYIIETGEIYEYDFKAKIFTLIQDRKVQ

Specific function: Reversible Hydration Of Carbon Dioxide. Carbon Dioxide Formed In The Bicarbonate-Dependent Decomposition Of Cyanate By Cyanase (Cyns) Diffuses Out Of The Cell Faster Than It Would Be Hydrated To Bicarbonate, So The Apparent Function Of This Enzyme Is To C

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=202, Percent_Identity=40.0990099009901, Blast_Score=170, Evalue=5e-44,
Organism=Escherichia coli, GI1786318, Length=210, Percent_Identity=32.8571428571429, Blast_Score=93, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI25147564, Length=244, Percent_Identity=27.8688524590164, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI115532990, Length=250, Percent_Identity=26.4, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6324292, Length=167, Percent_Identity=32.3353293413174, Blast_Score=81, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24645213, Length=243, Percent_Identity=26.7489711934156, Blast_Score=100, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 24209; Mature: 24209

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENLISGAIKFMQEDFKEHEELFESLKNKQNPHTLFIGCSDSRVIPNLITNTGPGELFVI
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHCCCCCCCEEEE
RNIANIVPPYRIGEDYLATTSAIEYALNSLHIKNIVVCGHSNCGGCNALYYSDEELNKIP
ECHHHHCCCCCCCCHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCEEEECCHHHHHCC
NVKKWLTMLDPIKKDVMIFARDDLAMRSWLTEKLNLVNSLQNILTYPGVQEALDEGKIEV
CHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEE
HAWYYIIETGEIYEYDFKAKIFTLIQDRKVQ
EEEEEEEECCCEEEEEHHHHHHHHHHCCCCC
>Mature Secondary Structure
MENLISGAIKFMQEDFKEHEELFESLKNKQNPHTLFIGCSDSRVIPNLITNTGPGELFVI
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHCCCCCCCEEEE
RNIANIVPPYRIGEDYLATTSAIEYALNSLHIKNIVVCGHSNCGGCNALYYSDEELNKIP
ECHHHHCCCCCCCCHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCEEEECCHHHHHCC
NVKKWLTMLDPIKKDVMIFARDDLAMRSWLTEKLNLVNSLQNILTYPGVQEALDEGKIEV
CHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEE
HAWYYIIETGEIYEYDFKAKIFTLIQDRKVQ
EEEEEEEECCCEEEEEHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]