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The map label for this gene is ttcA [H]

Identifier: 57237125

GI number: 57237125

Start: 121373

End: 122128

Strand: Direct

Name: ttcA [H]

Synonym: CJE0113

Alternate gene names: 57237125

Gene position: 121373-122128 (Clockwise)

Preceding gene: 57237124

Following gene: 57237126

Centisome position: 6.83

GC content: 35.58

Gene sequence:

>756_bases
ATGATAAATCTTAGCAAAAAACTCATACGCCAAGTTGCACAAGCTAATGCTAAATTTGGACTTATTAAAGATGGAGATAG
GGTTCTTTTAGGGCTTAGTGGCGGGAAAGATTCTTTGGCTTTAGCCCATCTTTTAAATCGTATGCAAGCTCACGCTCCTT
TTAAATTTGAACTTGAAGCGGTAACTTTGAGTTATGGTATGGGCGAGGATTATTCTCATCTTCATGCACATTGTGAAGAA
CACGGCATTAAACATAGCGTGCTTGATTCAAATATTTATGAAGTTTCAGGCGATACCATAAGAGAAAATTCAAGTTTTTG
TAGTTATTTTTCGAGAATGCGTCGTGGAGCTTTATATACTTACGCTCTTGAAAAAGGTTTTAACAAGCTTGCTATAGCTC
ATCATTTAGATGATGCAGCAGAAAGCTTTTTTATGAATTTTATTCATAATGGAGCTTTAAGAACCTTAGCGCCTATTTAT
CAAAGCAAACGCGGTATAACTGTGATACGCCCTTTGATTTTTGTGCGAGAAAGACAGCTTAGGGATAATGCTACGCAAAA
TGAACTTAGCGTGATAGGAAATGAATTTTGTCCTGGTATGAAACTCAGCGAAAAAAATGTGAAATTTCCACACGCTAGAG
AAGAAGCTAAACAGCTTTTAGCAAATTTAGAAAAAGATCATCCTAAGCTTTTTACAAGCTTAAAAACTGCTTTTACAAAT
TTACACACAGAAAGTTTTTGGCTTCAAAAGGCATAA

Upstream 100 bases:

>100_bases
GTGATAAAGCAGGGGAAAAGGCTGAATTTGATTTTGATGAGTTTGTGATCAATTCAGCTAAAATTTCAGCCAATTTTGTG
CTTAAAATGTGCGAGAAATT

Downstream 100 bases:

>100_bases
AAGCATGAAAAAAGCTTTTGTTTTAGTGGATTATCAAAATGATTTTATTGATGGAAGTTTAGGTTTTGATAAGGCTTTAA
AAATCAAAGAAAATATTCTT

Product: PP-loop family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MINLSKKLIRQVAQANAKFGLIKDGDRVLLGLSGGKDSLALAHLLNRMQAHAPFKFELEAVTLSYGMGEDYSHLHAHCEE
HGIKHSVLDSNIYEVSGDTIRENSSFCSYFSRMRRGALYTYALEKGFNKLAIAHHLDDAAESFFMNFIHNGALRTLAPIY
QSKRGITVIRPLIFVRERQLRDNATQNELSVIGNEFCPGMKLSEKNVKFPHAREEAKQLLANLEKDHPKLFTSLKTAFTN
LHTESFWLQKA

Sequences:

>Translated_251_residues
MINLSKKLIRQVAQANAKFGLIKDGDRVLLGLSGGKDSLALAHLLNRMQAHAPFKFELEAVTLSYGMGEDYSHLHAHCEE
HGIKHSVLDSNIYEVSGDTIRENSSFCSYFSRMRRGALYTYALEKGFNKLAIAHHLDDAAESFFMNFIHNGALRTLAPIY
QSKRGITVIRPLIFVRERQLRDNATQNELSVIGNEFCPGMKLSEKNVKFPHAREEAKQLLANLEKDHPKLFTSLKTAFTN
LHTESFWLQKA
>Mature_251_residues
MINLSKKLIRQVAQANAKFGLIKDGDRVLLGLSGGKDSLALAHLLNRMQAHAPFKFELEAVTLSYGMGEDYSHLHAHCEE
HGIKHSVLDSNIYEVSGDTIRENSSFCSYFSRMRRGALYTYALEKGFNKLAIAHHLDDAAESFFMNFIHNGALRTLAPIY
QSKRGITVIRPLIFVRERQLRDNATQNELSVIGNEFCPGMKLSEKNVKFPHAREEAKQLLANLEKDHPKLFTSLKTAFTN
LHTESFWLQKA

Specific function: Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) [H]

COG id: COG0037

COG function: function code D; Predicted ATPase of the PP-loop superfamily implicated in cell cycle control

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TtcA family [H]

Homologues:

Organism=Escherichia coli, GI1787606, Length=240, Percent_Identity=32.5, Blast_Score=137, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI193211090, Length=247, Percent_Identity=38.0566801619433, Blast_Score=132, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17540090, Length=229, Percent_Identity=28.3842794759825, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012089
- InterPro:   IPR014729
- InterPro:   IPR011063 [H]

Pfam domain/function: PF01171 ATP_bind_3 [H]

EC number: NA

Molecular weight: Translated: 28419; Mature: 28419

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINLSKKLIRQVAQANAKFGLIKDGDRVLLGLSGGKDSLALAHLLNRMQAHAPFKFELEA
CCCHHHHHHHHHHHCCCCCCEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEE
VTLSYGMGEDYSHLHAHCEEHGIKHSVLDSNIYEVSGDTIRENSSFCSYFSRMRRGALYT
EEEECCCCCCHHHHHHHHHHHCCCHHHHCCCCEECCCCHHHCCCHHHHHHHHHHHCCHHH
YALEKGFNKLAIAHHLDDAAESFFMNFIHNGALRTLAPIYQSKRGITVIRPLIFVRERQL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RDNATQNELSVIGNEFCPGMKLSEKNVKFPHAREEAKQLLANLEKDHPKLFTSLKTAFTN
HCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LHTESFWLQKA
HCCHHEEEECC
>Mature Secondary Structure
MINLSKKLIRQVAQANAKFGLIKDGDRVLLGLSGGKDSLALAHLLNRMQAHAPFKFELEA
CCCHHHHHHHHHHHCCCCCCEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEE
VTLSYGMGEDYSHLHAHCEEHGIKHSVLDSNIYEVSGDTIRENSSFCSYFSRMRRGALYT
EEEECCCCCCHHHHHHHHHHHCCCHHHHCCCCEECCCCHHHCCCHHHHHHHHHHHCCHHH
YALEKGFNKLAIAHHLDDAAESFFMNFIHNGALRTLAPIYQSKRGITVIRPLIFVRERQL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RDNATQNELSVIGNEFCPGMKLSEKNVKFPHAREEAKQLLANLEKDHPKLFTSLKTAFTN
HCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LHTESFWLQKA
HCCHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA