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The map label for this gene is fabD [H]

Identifier: 57237123

GI number: 57237123

Start: 119770

End: 120690

Strand: Direct

Name: fabD [H]

Synonym: CJE0111

Alternate gene names: 57237123

Gene position: 119770-120690 (Clockwise)

Preceding gene: 57237122

Following gene: 57237124

Centisome position: 6.74

GC content: 33.55

Gene sequence:

>921_bases
ATGAATGCTGCGTTTATATTTCCAGGTCAAGGCTCTCAAAGTCTTGGCATGGGAAAAGATTTTTATGAAAACTCTATAAA
AGCCAAAGAACTCCTTCAAAACGCAAGTGATTTTTGTAAGATTGATTTTAAACATTTGCTTTTTGAAGAAAACGAAAAAC
TCAATCAAAGTGAATTTACTCAACCCGCCATCGTTTTAAATTCCTTAATGGCTTATAGTGTTTTACTTGAAAAAAAACCT
GATTTAAGTTCGAAATTTGCTTTAGGGCATTCTTTGGGAGAATTTTCAGCCTTAGCTGTCAATGGTGCTTTTGATTTTTT
AGAGGCTCTTTCTTTGGTCAATAAAAGAGGGCTTTTCATGCAAGAAGATTGTGCAAAAGTTGAAGCAGGTATGATGGTGG
TTTTGGGGCTTGATGATGAAAAGGTTGAAGAGCTTTGTCAAAAAGCACAAAAAGAAAACAAGCAAATTTTCGCTGCAAAT
TATAACTGCGATGGACAAATCGTTGTAGCAGGTTTAAAACCTGATTTAGCAAGTTATGAAAGTGTATTTAAAGAAGCAGG
AGCTAAAAGAGCTATGCTTTTAAATATGAACGTGGCAAGTCATTGTCCTCTTTTGGAAAATGCTTCAGCTAAGCTTTGTG
TGGAGCTTGAAAAGGTGTTAAAACCAAATTTTAAAGCCGTAATTTCTAATGCAAATGCCAAAATTTATACAAGCAAAGAA
GAAGCCATTGAGCTTTTAAAAGCGCAACTTATCTCTCCTGTGCTTTATAAACAAAGCATTAAGGCATGTGAAAATGAAGT
AGATTATTTCATAGAATTTGGCGCAAGTGTGCTTAAGGGTTTGAATAAAAAAATCACTTCAAAAGAAACTTATGCTTTAA
CAAATATGAATGATATTGATGAATTTTTAAAGGTTGTATGA

Upstream 100 bases:

>100_bases
ATAGTTGTGGTTGTGGAAGCGGACATGGACACGATCATCATCACGGACATGGACATGGTGGTGGCGGTTGCTGTGGTGGC
GGCGGTTGCGGTTGTCATTA

Downstream 100 bases:

>100_bases
TGAAAATAGCAATTTTAGGAGCCATGAGTGAAGAAATCACTCCTTTACTTGAAACACTTAAAGATTATACGAAAATAGAA
CACGCTAACAATACTTATTA

Product: malonyl CoA-ACP transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MNAAFIFPGQGSQSLGMGKDFYENSIKAKELLQNASDFCKIDFKHLLFEENEKLNQSEFTQPAIVLNSLMAYSVLLEKKP
DLSSKFALGHSLGEFSALAVNGAFDFLEALSLVNKRGLFMQEDCAKVEAGMMVVLGLDDEKVEELCQKAQKENKQIFAAN
YNCDGQIVVAGLKPDLASYESVFKEAGAKRAMLLNMNVASHCPLLENASAKLCVELEKVLKPNFKAVISNANAKIYTSKE
EAIELLKAQLISPVLYKQSIKACENEVDYFIEFGASVLKGLNKKITSKETYALTNMNDIDEFLKVV

Sequences:

>Translated_306_residues
MNAAFIFPGQGSQSLGMGKDFYENSIKAKELLQNASDFCKIDFKHLLFEENEKLNQSEFTQPAIVLNSLMAYSVLLEKKP
DLSSKFALGHSLGEFSALAVNGAFDFLEALSLVNKRGLFMQEDCAKVEAGMMVVLGLDDEKVEELCQKAQKENKQIFAAN
YNCDGQIVVAGLKPDLASYESVFKEAGAKRAMLLNMNVASHCPLLENASAKLCVELEKVLKPNFKAVISNANAKIYTSKE
EAIELLKAQLISPVLYKQSIKACENEVDYFIEFGASVLKGLNKKITSKETYALTNMNDIDEFLKVV
>Mature_306_residues
MNAAFIFPGQGSQSLGMGKDFYENSIKAKELLQNASDFCKIDFKHLLFEENEKLNQSEFTQPAIVLNSLMAYSVLLEKKP
DLSSKFALGHSLGEFSALAVNGAFDFLEALSLVNKRGLFMQEDCAKVEAGMMVVLGLDDEKVEELCQKAQKENKQIFAAN
YNCDGQIVVAGLKPDLASYESVFKEAGAKRAMLLNMNVASHCPLLENASAKLCVELEKVLKPNFKAVISNANAKIYTSKE
EAIELLKAQLISPVLYKQSIKACENEVDYFIEFGASVLKGLNKKITSKETYALTNMNDIDEFLKVV

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=271, Percent_Identity=32.1033210332103, Blast_Score=104, Evalue=8e-23,
Organism=Escherichia coli, GI1787334, Length=297, Percent_Identity=36.026936026936, Blast_Score=151, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI71984332, Length=269, Percent_Identity=26.7657992565056, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24665753, Length=294, Percent_Identity=30.6122448979592, Blast_Score=105, Evalue=5e-23,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33844; Mature: 33844

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAAFIFPGQGSQSLGMGKDFYENSIKAKELLQNASDFCKIDFKHLLFEENEKLNQSEFT
CCCEEEECCCCCCCCCCCHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHCC
QPAIVLNSLMAYSVLLEKKPDLSSKFALGHSLGEFSALAVNGAFDFLEALSLVNKRGLFM
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHEEECHHHHHHHHHHHHHHCCCCC
QEDCAKVEAGMMVVLGLDDEKVEELCQKAQKENKQIFAANYNCDGQIVVAGLKPDLASYE
HHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCCHHHHH
SVFKEAGAKRAMLLNMNVASHCPLLENASAKLCVELEKVLKPNFKAVISNANAKIYTSKE
HHHHHCCCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCCEEEECHH
EAIELLKAQLISPVLYKQSIKACENEVDYFIEFGASVLKGLNKKITSKETYALTNMNDID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCHHHHH
EFLKVV
HHHHCC
>Mature Secondary Structure
MNAAFIFPGQGSQSLGMGKDFYENSIKAKELLQNASDFCKIDFKHLLFEENEKLNQSEFT
CCCEEEECCCCCCCCCCCHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHCC
QPAIVLNSLMAYSVLLEKKPDLSSKFALGHSLGEFSALAVNGAFDFLEALSLVNKRGLFM
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHEEECHHHHHHHHHHHHHHCCCCC
QEDCAKVEAGMMVVLGLDDEKVEELCQKAQKENKQIFAANYNCDGQIVVAGLKPDLASYE
HHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCCHHHHH
SVFKEAGAKRAMLLNMNVASHCPLLENASAKLCVELEKVLKPNFKAVISNANAKIYTSKE
HHHHHCCCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCCEEEECHH
EAIELLKAQLISPVLYKQSIKACENEVDYFIEFGASVLKGLNKKITSKETYALTNMNDID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCHHHHH
EFLKVV
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]