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The map label for this gene is slyD [H]

Identifier: 57237122

GI number: 57237122

Start: 119201

End: 119770

Strand: Direct

Name: slyD [H]

Synonym: CJE0110

Alternate gene names: 57237122

Gene position: 119201-119770 (Clockwise)

Preceding gene: 57237121

Following gene: 57237123

Centisome position: 6.7

GC content: 36.84

Gene sequence:

>570_bases
ATGGCTATAGAAAAAAATAGTGTAGTTTCAATGTTTTATGAGTTAAAAGATGCAAATACAAATGAAGTTTTAGAATCAAA
TTTATATTCTCAACCTATTTCTTTTATTTTAGGCAAAGGTCAGATTTTAGAAAGCTTAGAAGAAGAAGTGATGAAGCTTG
ATTGCCCTAGCAATGCTGATGTGGTAATTAAAAAAGAAAAAGGTTTAGGCGAATACGATGAAAATGCCGTTCAAACTTTA
CCAAAAGAGCAATTTGCAGGTATTGATTTAAAAGTAGGTATGGAGCTTTTTGGCGAAGGTGAAAATGGCGAAACCGTTCG
TGTAACTGTAAAAGAAATTGGTGAAAATGATGTGACAATTGACTATAATCATCCTTATGCAGGTCGTGATTTGCTTTTTT
CTTTAAATATCGTAGATGCTAGAGTTGCGAGTGAAGATGAAATTCTTACAGGTATTATCGCAGGAAGTCATAGTTGTGGT
TGTGGAAGCGGACATGGACACGATCATCATCACGGACATGGACATGGTGGTGGCGGTTGCTGTGGTGGCGGCGGTTGCGG
TTGTCATTAA

Upstream 100 bases:

>100_bases
CAAAAACAGCAAATGGTTTTTATAAAGCTTTAAAAACTAATTATCCAAATTCACCCGAAGCAAAAGCTTCACCTAATAGA
AAATAAATTAAGGAGATAAA

Downstream 100 bases:

>100_bases
TGAATGCTGCGTTTATATTTCCAGGTCAAGGCTCTCAAAGTCTTGGCATGGGAAAAGATTTTTATGAAAACTCTATAAAA
GCCAAAGAACTCCTTCAAAA

Product: FKBP-type peptidyl-prolyl cis-trans isomerase SlyD

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 189; Mature: 188

Protein sequence:

>189_residues
MAIEKNSVVSMFYELKDANTNEVLESNLYSQPISFILGKGQILESLEEEVMKLDCPSNADVVIKKEKGLGEYDENAVQTL
PKEQFAGIDLKVGMELFGEGENGETVRVTVKEIGENDVTIDYNHPYAGRDLLFSLNIVDARVASEDEILTGIIAGSHSCG
CGSGHGHDHHHGHGHGGGGCCGGGGCGCH

Sequences:

>Translated_189_residues
MAIEKNSVVSMFYELKDANTNEVLESNLYSQPISFILGKGQILESLEEEVMKLDCPSNADVVIKKEKGLGEYDENAVQTL
PKEQFAGIDLKVGMELFGEGENGETVRVTVKEIGENDVTIDYNHPYAGRDLLFSLNIVDARVASEDEILTGIIAGSHSCG
CGSGHGHDHHHGHGHGGGGCCGGGGCGCH
>Mature_188_residues
AIEKNSVVSMFYELKDANTNEVLESNLYSQPISFILGKGQILESLEEEVMKLDCPSNADVVIKKEKGLGEYDENAVQTLP
KEQFAGIDLKVGMELFGEGENGETVRVTVKEIGENDVTIDYNHPYAGRDLLFSLNIVDARVASEDEILTGIIAGSHSCGC
GSGHGHDHHHGHGHGGGGCCGGGGCGCH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=149, Percent_Identity=33.5570469798658, Blast_Score=81, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 20161; Mature: 20029

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIEKNSVVSMFYELKDANTNEVLESNLYSQPISFILGKGQILESLEEEVMKLDCPSNAD
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHCCCCCCCCC
VVIKKEKGLGEYDENAVQTLPKEQFAGIDLKVGMELFGEGENGETVRVTVKEIGENDVTI
EEEEECCCCCCCCCHHHHHCCHHHHCCCEEEECHHEECCCCCCCEEEEEHHHCCCCCEEE
DYNHPYAGRDLLFSLNIVDARVASEDEILTGIIAGSHSCGCGSGHGHDHHHGHGHGGGGC
EECCCCCCCEEEEEEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
CGGGGCGCH
CCCCCCCCC
>Mature Secondary Structure 
AIEKNSVVSMFYELKDANTNEVLESNLYSQPISFILGKGQILESLEEEVMKLDCPSNAD
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHCCCCCCCCC
VVIKKEKGLGEYDENAVQTLPKEQFAGIDLKVGMELFGEGENGETVRVTVKEIGENDVTI
EEEEECCCCCCCCCHHHHHCCHHHHCCCEEEECHHEECCCCCCCEEEEEHHHCCCCCEEE
DYNHPYAGRDLLFSLNIVDARVASEDEILTGIIAGSHSCGCGSGHGHDHHHGHGHGGGGC
EECCCCCCCEEEEEEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
CGGGGCGCH
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]