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The map label for this gene is aroQ

Identifier: 57237076

GI number: 57237076

Start: 78262

End: 78741

Strand: Reverse

Name: aroQ

Synonym: CJE0063

Alternate gene names: 57237076

Gene position: 78741-78262 (Counterclockwise)

Preceding gene: 57237080

Following gene: 57237075

Centisome position: 4.43

GC content: 35.21

Gene sequence:

>480_bases
ATGAAAATAATGATTATCCAAGGCCCAAATGTTAATATGCTTGGCGTAAGAGAAGTGGGAATTTATGGTGCTATGAAAAT
GGAAGAAATTCATGAGCAAATGAAACTTGCAGCATCTCAAAACAATGTAGAACTTGACTTTTTCCAAAGTAATTTTGAAG
GTGAAATCGTAGATAAAATTCAAGAATGTCTTGGCACAGTTGATGGAATTATTATCAACGCAGCAGGCTATACTCATACT
TCAGTAGCTATTCGCGATGCTATTGCAGCAGTAGCTTTGCCTACAATTGAAGTACATATTAGCAATGTTTATCGCAGAGA
AGAATTTCGTCAAAAAAGTCTTATAGCGCCTGTATGTTCTGGAACTATTGTTGGTTTTGGTCCTTTTGGCTATCACTTGG
CTTTAATGGGTATAATTCAAATTTGCGAACAAATAAAAAATTTGCGTGCGATGCAACAAGCACAACAAACGAATAAATAA

Upstream 100 bases:

>100_bases
CTATAAACACGATTTTCCTTTCAAAAATTACATTGTAGCAAAAATTTATTTTTAAAATGTTATAATAAAAGGTTAAAAAT
AAATTTTTAAGGTTAAATCC

Downstream 100 bases:

>100_bases
TAATGCTAAAAATTCAAGGAGTAAAACACTTTGAAAAAAGTCGTTTTTTTCCTTTTTTTAGTCAAAATATACGATCTTTT
AAATATTTAGCTCTTATAGG

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MKIMIIQGPNVNMLGVREVGIYGAMKMEEIHEQMKLAASQNNVELDFFQSNFEGEIVDKIQECLGTVDGIIINAAGYTHT
SVAIRDAIAAVALPTIEVHISNVYRREEFRQKSLIAPVCSGTIVGFGPFGYHLALMGIIQICEQIKNLRAMQQAQQTNK

Sequences:

>Translated_159_residues
MKIMIIQGPNVNMLGVREVGIYGAMKMEEIHEQMKLAASQNNVELDFFQSNFEGEIVDKIQECLGTVDGIIINAAGYTHT
SVAIRDAIAAVALPTIEVHISNVYRREEFRQKSLIAPVCSGTIVGFGPFGYHLALMGIIQICEQIKNLRAMQQAQQTNK
>Mature_159_residues
MKIMIIQGPNVNMLGVREVGIYGAMKMEEIHEQMKLAASQNNVELDFFQSNFEGEIVDKIQECLGTVDGIIINAAGYTHT
SVAIRDAIAAVALPTIEVHISNVYRREEFRQKSLIAPVCSGTIVGFGPFGYHLALMGIIQICEQIKNLRAMQQAQQTNK

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_CAMJ8 (A8FJM2)

Other databases:

- EMBL:   CP000814
- RefSeq:   YP_001481636.1
- ProteinModelPortal:   A8FJM2
- SMR:   A8FJM2
- STRING:   A8FJM2
- GeneID:   5617326
- GenomeReviews:   CP000814_GR
- KEGG:   cju:C8J_0059
- eggNOG:   COG0757
- HOGENOM:   HBG284657
- OMA:   HSYIAPI
- ProtClustDB:   PRK05395
- BioCyc:   CJEJ407148:C8J_0059-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 17596; Mature: 17596

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 22-22 ACT_SITE 99-99 BINDING 73-73 BINDING 79-79 BINDING 86-86 BINDING 110-110

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIMIIQGPNVNMLGVREVGIYGAMKMEEIHEQMKLAASQNNVELDFFQSNFEGEIVDKI
CEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHH
QECLGTVDGIIINAAGYTHTSVAIRDAIAAVALPTIEVHISNVYRREEFRQKSLIAPVCS
HHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHC
GTIVGFGPFGYHLALMGIIQICEQIKNLRAMQQAQQTNK
CCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIMIIQGPNVNMLGVREVGIYGAMKMEEIHEQMKLAASQNNVELDFFQSNFEGEIVDKI
CEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHH
QECLGTVDGIIINAAGYTHTSVAIRDAIAAVALPTIEVHISNVYRREEFRQKSLIAPVCS
HHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHC
GTIVGFGPFGYHLALMGIIQICEQIKNLRAMQQAQQTNK
CCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA