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The map label for this gene is yabD [H]

Identifier: 57236957

GI number: 57236957

Start: 683058

End: 683873

Strand: Direct

Name: yabD [H]

Synonym: CJE0747

Alternate gene names: 57236957

Gene position: 683058-683873 (Clockwise)

Preceding gene: 57236956

Following gene: 57236958

Centisome position: 38.42

GC content: 29.78

Gene sequence:

>816_bases
ATGTTCTTAAATCTTGATTTTCAAGATGGTTTAAGGATTGTTGATACACATTGCCATCTAGACAGTGAAGCATTTAAAGA
TGATTTAGATGAAACTTTAAATCGTGCTTTTAAAAATGGTATAGAGAAAATCATCATACCTGGTGCTGATATAAAAGATT
TGCCCTATGCAGCTACAATTGCTCATAAATATAAAAATATTTTTTTTGCAGCAGGGGTGCATCCTTATGAAATTGATAAT
TATGATGAGAAAATTTTAAGGCAGTATTTATGCGATGAAAAATGTGTAGCTGTAGGTGAATGTGGGCTTGATTATTTTCG
TTTTAAAAGTGATCTTGCTGAAGAAATTCAAAAAGAAAAAGAAAATCAAAAAAAGATTTTTATCGCACAGCTTGAACTTG
CTATTGAATTTAAAAAACCTGTTATCATTCACTCAAGAGAAGCAAATCATGATACCTATGAGATTTTACATGGGTATTCT
AAGGATCTTGTAGGAGGAGTTTTACACTGCTTTAATGCAAGCGAACATTTGCTAACTCTTTTTGAAGATGGATTTTATTT
TGGTATTGGGGGAGTTTTAACTTTTAAAAATGCTAAGAAATTAGTTGAAATTTTACCTAAAATTCCAAAAGATAGACTAC
TACTTGAAACTGATGCTCCATATCTTACTCCAGAGCCTTATCGCGGTAAAAGAAATGAACCTTTGTTAACTCAATTTGTA
GCAAACAAAATGTGTGAAGTATTGAATTTATCAAGAAAAGAACTTCTAGAAATTTGTTTTAACAATTCTGAAAAATTATT
TTTTAAAGGTTATTAA

Upstream 100 bases:

>100_bases
TGGTTTTTGGAAAAAGTGGAGATAAGATTGATTCTTTGGTTGATAAAGCAAGTAAAATATTGTCTCAAGCAAAAGATAAT
GGCAAGGATAGAGTTGAAGT

Downstream 100 bases:

>100_bases
TGAAAAAAATTTTATTGTGTTTTTTAATATGTTTTAATTTTCTTTTTGCACAAATTAATACTCCTGAATTTTATGAAAGA
CAAATGAATGTTTTAAGAAA

Product: TatD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MFLNLDFQDGLRIVDTHCHLDSEAFKDDLDETLNRAFKNGIEKIIIPGADIKDLPYAATIAHKYKNIFFAAGVHPYEIDN
YDEKILRQYLCDEKCVAVGECGLDYFRFKSDLAEEIQKEKENQKKIFIAQLELAIEFKKPVIIHSREANHDTYEILHGYS
KDLVGGVLHCFNASEHLLTLFEDGFYFGIGGVLTFKNAKKLVEILPKIPKDRLLLETDAPYLTPEPYRGKRNEPLLTQFV
ANKMCEVLNLSRKELLEICFNNSEKLFFKGY

Sequences:

>Translated_271_residues
MFLNLDFQDGLRIVDTHCHLDSEAFKDDLDETLNRAFKNGIEKIIIPGADIKDLPYAATIAHKYKNIFFAAGVHPYEIDN
YDEKILRQYLCDEKCVAVGECGLDYFRFKSDLAEEIQKEKENQKKIFIAQLELAIEFKKPVIIHSREANHDTYEILHGYS
KDLVGGVLHCFNASEHLLTLFEDGFYFGIGGVLTFKNAKKLVEILPKIPKDRLLLETDAPYLTPEPYRGKRNEPLLTQFV
ANKMCEVLNLSRKELLEICFNNSEKLFFKGY
>Mature_271_residues
MFLNLDFQDGLRIVDTHCHLDSEAFKDDLDETLNRAFKNGIEKIIIPGADIKDLPYAATIAHKYKNIFFAAGVHPYEIDN
YDEKILRQYLCDEKCVAVGECGLDYFRFKSDLAEEIQKEKENQKKIFIAQLELAIEFKKPVIIHSREANHDTYEILHGYS
KDLVGGVLHCFNASEHLLTLFEDGFYFGIGGVLTFKNAKKLVEILPKIPKDRLLLETDAPYLTPEPYRGKRNEPLLTQFV
ANKMCEVLNLSRKELLEICFNNSEKLFFKGY

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349734, Length=284, Percent_Identity=27.8169014084507, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI14042943, Length=277, Percent_Identity=28.8808664259928, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI110349730, Length=284, Percent_Identity=27.112676056338, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI226061853, Length=291, Percent_Identity=27.8350515463918, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI225903424, Length=230, Percent_Identity=32.6086956521739, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI226061614, Length=262, Percent_Identity=27.0992366412214, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI225903439, Length=258, Percent_Identity=28.2945736434109, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI226061595, Length=248, Percent_Identity=27.4193548387097, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1787342, Length=260, Percent_Identity=35.3846153846154, Blast_Score=164, Evalue=5e-42,
Organism=Escherichia coli, GI48994985, Length=232, Percent_Identity=34.051724137931, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI87082439, Length=263, Percent_Identity=33.0798479087452, Blast_Score=134, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI17559024, Length=286, Percent_Identity=30.0699300699301, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71980746, Length=267, Percent_Identity=30.3370786516854, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17543026, Length=190, Percent_Identity=31.5789473684211, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24648690, Length=241, Percent_Identity=31.9502074688797, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI221330018, Length=291, Percent_Identity=28.8659793814433, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24586117, Length=291, Percent_Identity=28.8659793814433, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.- [C]

Molecular weight: Translated: 31266; Mature: 31266

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLNLDFQDGLRIVDTHCHLDSEAFKDDLDETLNRAFKNGIEKIIIPGADIKDLPYAATI
CEEECCHHCCCEEEEHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHH
AHKYKNIFFAAGVHPYEIDNYDEKILRQYLCDEKCVAVGECGLDYFRFKSDLAEEIQKEK
HHHHHHEEEECCCCCEECCCHHHHHHHHHHCCCHHEEHHHCCHHHHHHHHHHHHHHHHHH
ENQKKIFIAQLELAIEFKKPVIIHSREANHDTYEILHGYSKDLVGGVLHCFNASEHLLTL
CCCCEEEEEEEEEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FEDGFYFGIGGVLTFKNAKKLVEILPKIPKDRLLLETDAPYLTPEPYRGKRNEPLLTQFV
HHCCEEEECCCEEEEHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHH
ANKMCEVLNLSRKELLEICFNNSEKLFFKGY
HHHHHHHHCCCHHHHHHHHHCCCCEEEEECC
>Mature Secondary Structure
MFLNLDFQDGLRIVDTHCHLDSEAFKDDLDETLNRAFKNGIEKIIIPGADIKDLPYAATI
CEEECCHHCCCEEEEHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHH
AHKYKNIFFAAGVHPYEIDNYDEKILRQYLCDEKCVAVGECGLDYFRFKSDLAEEIQKEK
HHHHHHEEEECCCCCEECCCHHHHHHHHHHCCCHHEEHHHCCHHHHHHHHHHHHHHHHHH
ENQKKIFIAQLELAIEFKKPVIIHSREANHDTYEILHGYSKDLVGGVLHCFNASEHLLTL
CCCCEEEEEEEEEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FEDGFYFGIGGVLTFKNAKKLVEILPKIPKDRLLLETDAPYLTPEPYRGKRNEPLLTQFV
HHCCEEEECCCEEEEHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHH
ANKMCEVLNLSRKELLEICFNNSEKLFFKGY
HHHHHHHHCCCHHHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]