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The map label for this gene is mch [H]

Identifier: 21228755

GI number: 21228755

Start: 3168334

End: 3169299

Strand: Reverse

Name: mch [H]

Synonym: MM_2653

Alternate gene names: 21228755

Gene position: 3169299-3168334 (Counterclockwise)

Preceding gene: 21228756

Following gene: 21228754

Centisome position: 77.37

GC content: 47.62

Gene sequence:

>966_bases
TTGATAAGCGTTAACGAAATGGGCTCATACGTCATCGAAGAGATGCTCGACTGGAGCGAAGACCTGAAAACGGAAGTAAT
CAAGCTTGAAAATGGCGCCACAATCATCGACTGTGGGATTAAAGCCGAAGGCGGATATGAAGCCGGGATGTACCTTGCAA
GACTCTGCCTTGCTGACCTTGCTGACCTTAAATACAGCACCTTTGACCTCAACGGCATCAAATGGCCTGCCATCCAGGTA
GCAACCGACAACCCTGTAATCGCCTGTATGGCTTCCCAGTATGCTGGCTGGAGAATCTCTGTAGGCAACTATTTCGGTAT
GGGTTCAGGTCCCGCACGTGCGCTTGGCTTAAAGCCAAAAGAGCTCTATGAAGAGATCGGTTATGAAGATGATTTCGAAG
CTGCTGTCCTTGTCATGGAATCCGACAAACTCCCGGATGAAAAAGTCGTGGAATACATTGCAAAACACTGCAGTGTAGAC
CCGGAAAATGTCATGATCGCTGTTGCGCCTACAGCTTCCATTGCAGGTTCTGTCCAGATTTCAGCCCGTGTCGTTGAAAC
CGGTATCCACAAATTTGAATCTATTGGCTTTGACATCAACTGCATAAAGAGCGGGTACGGAATTGCCCCTATCGCCCCCA
TAGTTGGAAACGATGTCCAGTGCATGGGTTCAACCAATGACTGTGTCATTTATTGCGGCGAAACCAACTATACTGTCAGC
TTCGAAGGTGAACTGGCTAAACTCGAAGACTTTGTAAGAAAAGTCCCCTCAACAACCTCAGACGATTTCGGAAAGCCGTT
CTACCAGACCTTCAAGGCAGCGAACTTTGACTTCTTCAAAGTCGACGCAGGCATGTTCGCTCCTGCAAGAGTAACAGTAA
ACGACTTAAAGAATAAAAAGACAATTTCGAGCGGTGGGCTCTACCCCGAAATCCTGCTTGAATCCTTCGGAATCAGGAAA
GTTTGA

Upstream 100 bases:

>100_bases
CAATACTCTGCTTACAGTAATTCCTGTATGTAAACAGTATCAATAGACTATTTCGAGAACCGGGACAAACAATTCTCGGA
CTGACATGTAAGGTGATATT

Downstream 100 bases:

>100_bases
GAAGGCATTCACCTCATCTCATTCTTCTCTTATTTTTCTCCACATTATTTTTCTCCACTTTTCCCCTGTTTTCAATATTT
TTCCAGTTTTGGCAGTCCTG

Product: N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase

Products: NA

Alternate protein names: Methenyl-H4MPT cyclohydrolase [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MISVNEMGSYVIEEMLDWSEDLKTEVIKLENGATIIDCGIKAEGGYEAGMYLARLCLADLADLKYSTFDLNGIKWPAIQV
ATDNPVIACMASQYAGWRISVGNYFGMGSGPARALGLKPKELYEEIGYEDDFEAAVLVMESDKLPDEKVVEYIAKHCSVD
PENVMIAVAPTASIAGSVQISARVVETGIHKFESIGFDINCIKSGYGIAPIAPIVGNDVQCMGSTNDCVIYCGETNYTVS
FEGELAKLEDFVRKVPSTTSDDFGKPFYQTFKAANFDFFKVDAGMFAPARVTVNDLKNKKTISSGGLYPEILLESFGIRK
V

Sequences:

>Translated_321_residues
MISVNEMGSYVIEEMLDWSEDLKTEVIKLENGATIIDCGIKAEGGYEAGMYLARLCLADLADLKYSTFDLNGIKWPAIQV
ATDNPVIACMASQYAGWRISVGNYFGMGSGPARALGLKPKELYEEIGYEDDFEAAVLVMESDKLPDEKVVEYIAKHCSVD
PENVMIAVAPTASIAGSVQISARVVETGIHKFESIGFDINCIKSGYGIAPIAPIVGNDVQCMGSTNDCVIYCGETNYTVS
FEGELAKLEDFVRKVPSTTSDDFGKPFYQTFKAANFDFFKVDAGMFAPARVTVNDLKNKKTISSGGLYPEILLESFGIRK
V
>Mature_321_residues
MISVNEMGSYVIEEMLDWSEDLKTEVIKLENGATIIDCGIKAEGGYEAGMYLARLCLADLADLKYSTFDLNGIKWPAIQV
ATDNPVIACMASQYAGWRISVGNYFGMGSGPARALGLKPKELYEEIGYEDDFEAAVLVMESDKLPDEKVVEYIAKHCSVD
PENVMIAVAPTASIAGSVQISARVVETGIHKFESIGFDINCIKSGYGIAPIAPIVGNDVQCMGSTNDCVIYCGETNYTVS
FEGELAKLEDFVRKVPSTTSDDFGKPFYQTFKAANFDFFKVDAGMFAPARVTVNDLKNKKTISSGGLYPEILLESFGIRK
V

Specific function: Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT(+) [H]

COG id: COG3252

COG function: function code H; Methenyltetrahydromethanopterin cyclohydrolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MCH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003209 [H]

Pfam domain/function: PF02289 MCH [H]

EC number: =3.5.4.27 [H]

Molecular weight: Translated: 34982; Mature: 34982

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVNEMGSYVIEEMLDWSEDLKTEVIKLENGATIIDCGIKAEGGYEAGMYLARLCLADL
CCCHHHHHHHHHHHHHCCHHHHHEEEEEECCCCEEEEECEECCCCCHHHHHHHHHHHHHH
ADLKYSTFDLNGIKWPAIQVATDNPVIACMASQYAGWRISVGNYFGMGSGPARALGLKPK
HHCCEEEEECCCEECCEEEEECCCCEEEEEECCCCCEEEECCCEECCCCCCCCCCCCCHH
ELYEEIGYEDDFEAAVLVMESDKLPDEKVVEYIAKHCSVDPENVMIAVAPTASIAGSVQI
HHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCHHEEEEEECCCCCCCCEEE
SARVVETGIHKFESIGFDINCIKSGYGIAPIAPIVGNDVQCMGSTNDCVIYCGETNYTVS
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHCCCCEEEECCCCCEEEEECCCCEEEE
FEGELAKLEDFVRKVPSTTSDDFGKPFYQTFKAANFDFFKVDAGMFAPARVTVNDLKNKK
ECCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCEEEHHHCCCCC
TISSGGLYPEILLESFGIRKV
CCCCCCCCHHHHHHHCCCCCC
>Mature Secondary Structure
MISVNEMGSYVIEEMLDWSEDLKTEVIKLENGATIIDCGIKAEGGYEAGMYLARLCLADL
CCCHHHHHHHHHHHHHCCHHHHHEEEEEECCCCEEEEECEECCCCCHHHHHHHHHHHHHH
ADLKYSTFDLNGIKWPAIQVATDNPVIACMASQYAGWRISVGNYFGMGSGPARALGLKPK
HHCCEEEEECCCEECCEEEEECCCCEEEEEECCCCCEEEECCCEECCCCCCCCCCCCCHH
ELYEEIGYEDDFEAAVLVMESDKLPDEKVVEYIAKHCSVDPENVMIAVAPTASIAGSVQI
HHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCHHEEEEEECCCCCCCCEEE
SARVVETGIHKFESIGFDINCIKSGYGIAPIAPIVGNDVQCMGSTNDCVIYCGETNYTVS
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHCCCCEEEECCCCCEEEEECCCCEEEE
FEGELAKLEDFVRKVPSTTSDDFGKPFYQTFKAANFDFFKVDAGMFAPARVTVNDLKNKK
ECCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCEEEHHHCCCCC
TISSGGLYPEILLESFGIRKV
CCCCCCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]