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The map label for this gene is 21228740

Identifier: 21228740

GI number: 21228740

Start: 3146673

End: 3148832

Strand: Reverse

Name: 21228740

Synonym: MM_2638

Alternate gene names: NA

Gene position: 3148832-3146673 (Counterclockwise)

Preceding gene: 21228741

Following gene: 21228739

Centisome position: 76.87

GC content: 46.06

Gene sequence:

>2160_bases
ATGTCCGTACTTGAGGGCATAGAGGGTATAAGAAACAATAACGAAACCGGAGAAAGCTGGTTTGTTTACATAAACGGAAC
ACAGGCTGGAGAAGACTTCGGAATGAACCCCGTAAGTAATGGTACCAATCTCAGCTTCTGGTACACAGATGAAGAAAACG
GAGTAGCTGCGCTGGATAATGCGACCTATCTGGCAAACATTACGGTTGCCATAGAAGAATTAGAGGAGCCAGCTGAAGAA
AACGATATAATTGAAACTGCCACTGAAGCTGGAAATTTTTCAACCCTCCTGACAGCGATTGAGGCTGCAAACCTCACAGA
TACCCTTAAAGGGGAAGGTCCTTTCACGGTCTTTGCCCCTACAGATGAAGCCTTCAGTGCACTGCCCAACGGAACTATCG
AGGCTCTCCTGAACGACACGGATGCACTGACCAATATTCTCCTCTACCACGTTGCAGATGAGAGGCTGATGGCAGAAGAT
GTTGTCAACCTGACCAACATTACAACCCTTCAGGGCGGCGAACTACCTGTCAATGTGACTGAAGAAGGGGTATTCGTAGG
GGAAGCAGAAATTATAGTGCAGGACGTAAATGCCAGCAATGGAGTAATCCACGTAATAGATGCAGTCCTTATTCCGGAAG
AAGGCATGGAACCTGAACCAGAACCCGGACAAAATGTAACAGAACTGTATAACGATACAGTGAGCCTGACTGAAGGGAAC
TTCACACTTATGCCGGAAAACTCCACAGAGAGCTATGCAATAAATAACTTTACGGATATCGGGGCTCTCAATGCAGCAGG
ACTTGACTTTAACGTATCGTTAATGCAAAACATGACAGGGAATGCAGCAAACATGACTGCTGTACCGTTTACACTCCAGA
GCGTAGAGGGTATAAGGAATAATAACACAACCGGGGAAGAATGGTTTCTTTATATTAACGGGGAGCCTGCTGAAGAAGAC
TTCGGAATGAATAATGTAAGTGCAGGAGACAACCTCAGCTTCTGGTACACAACTGAAAAGGGCGGAGAAGCAGCAGTAGA
AAATGCAAGCTATGTGGCAAACATTACTGTTTCCGAACTGAGAGCAAACGCAAATATCATCCCTGCAGCACAGAACCAGA
CGAACCTGACAGTATTTGTAGATGCAGTACAGACCGCAAACCTGACACAGACCCTTGACGGGACAGGACCCTATACCGTC
TGTATCCCGAGTGATGAAGCATTCAATAAGCTGCCAGAAGGGACACGCAATCAGCTTATGAACAATACCACTCTGCTCAA
CCAGGTACTTTCATACCATGTAGTGAGCGGAAGATACACGTACGAGCAGCTTATCGGAATGAATAATATTACCAATATCC
AGGGCAATGTGCTTCAGGTCAATGCCATAGGGAATAATATCACAATACAAAACGTAAGTGTCACCCAGATAATAGTTGTG
AACAATGGGGTCATCTGCATAATTGATGAGGTGCTTATTCCACCAGACGGCGAAATTCCCGCGGACAATCAGACCGACGG
CGGCCAGATAGATGATAACCAGACAGATGGAGGCCAGATGGATGGTAACCAGACAGACGGAGATCAGATAGACGGTGGCC
AGATGGATGGAAATCAGACTGATGGAAACCAGACCGCGGACAATTTGACAGGGGACTGGTATTTCTTCTCGATTCCTTTC
GAAGCCAACAACACAAGCGTTGAGTATCTTCTTTCGGATGTGAACTACACCTCCCTGATATATTATAACGCTTCAACCAA
ACTCTTCGAAGAAGTCACGGAAATTGAACCTCTAAAAGGATACTGGATCAACGTTCCCGATGGAACCGGGTTCAACGCTT
CGGAACAGTTCTCTTCAGTGGAGAAGAAACAGATTGAAGCTCCTCCGAGTTTGCAGGTATATCCGGGCTGGAACGCTCTT
GGTTCACCGGTAAATGAAACGGTGCCTGCAGAAGCTGCATTCATAGCCCTTAATAACTCGTATGCAAAAATCGTGGGACC
GTGGGTACCTGGCAATAATACCACAGGTTATTACCAGTACGTAGGCTATAATGGCCTTAACGGGACAATAGGCGAGAACC
AGCTTGGCGCAGATGAATTTGAAGTTGAACCCTATGAGGGTTACTGGGTCTTTATAAGACAGGAAAATTTGTATGCATAA

Upstream 100 bases:

>100_bases
CTATACAGTTGACAATTTCACAGATATAGGAGCTCTCAATGCAACCGGGCTTCAGTATAATGTGTCCGTACATGGTGTGA
ACCTGACCAATATGACCAAT

Downstream 100 bases:

>100_bases
GGGGGCTGCCTGAAAACAACAGCATAGAAAATAAATGGATATAAGAATTCATAAAAAGGAAAGAAAGAGATTTCCACCCT
GGAAATTTCTTTTTTAATTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 719; Mature: 718

Protein sequence:

>719_residues
MSVLEGIEGIRNNNETGESWFVYINGTQAGEDFGMNPVSNGTNLSFWYTDEENGVAALDNATYLANITVAIEELEEPAEE
NDIIETATEAGNFSTLLTAIEAANLTDTLKGEGPFTVFAPTDEAFSALPNGTIEALLNDTDALTNILLYHVADERLMAED
VVNLTNITTLQGGELPVNVTEEGVFVGEAEIIVQDVNASNGVIHVIDAVLIPEEGMEPEPEPGQNVTELYNDTVSLTEGN
FTLMPENSTESYAINNFTDIGALNAAGLDFNVSLMQNMTGNAANMTAVPFTLQSVEGIRNNNTTGEEWFLYINGEPAEED
FGMNNVSAGDNLSFWYTTEKGGEAAVENASYVANITVSELRANANIIPAAQNQTNLTVFVDAVQTANLTQTLDGTGPYTV
CIPSDEAFNKLPEGTRNQLMNNTTLLNQVLSYHVVSGRYTYEQLIGMNNITNIQGNVLQVNAIGNNITIQNVSVTQIIVV
NNGVICIIDEVLIPPDGEIPADNQTDGGQIDDNQTDGGQMDGNQTDGDQIDGGQMDGNQTDGNQTADNLTGDWYFFSIPF
EANNTSVEYLLSDVNYTSLIYYNASTKLFEEVTEIEPLKGYWINVPDGTGFNASEQFSSVEKKQIEAPPSLQVYPGWNAL
GSPVNETVPAEAAFIALNNSYAKIVGPWVPGNNTTGYYQYVGYNGLNGTIGENQLGADEFEVEPYEGYWVFIRQENLYA

Sequences:

>Translated_719_residues
MSVLEGIEGIRNNNETGESWFVYINGTQAGEDFGMNPVSNGTNLSFWYTDEENGVAALDNATYLANITVAIEELEEPAEE
NDIIETATEAGNFSTLLTAIEAANLTDTLKGEGPFTVFAPTDEAFSALPNGTIEALLNDTDALTNILLYHVADERLMAED
VVNLTNITTLQGGELPVNVTEEGVFVGEAEIIVQDVNASNGVIHVIDAVLIPEEGMEPEPEPGQNVTELYNDTVSLTEGN
FTLMPENSTESYAINNFTDIGALNAAGLDFNVSLMQNMTGNAANMTAVPFTLQSVEGIRNNNTTGEEWFLYINGEPAEED
FGMNNVSAGDNLSFWYTTEKGGEAAVENASYVANITVSELRANANIIPAAQNQTNLTVFVDAVQTANLTQTLDGTGPYTV
CIPSDEAFNKLPEGTRNQLMNNTTLLNQVLSYHVVSGRYTYEQLIGMNNITNIQGNVLQVNAIGNNITIQNVSVTQIIVV
NNGVICIIDEVLIPPDGEIPADNQTDGGQIDDNQTDGGQMDGNQTDGDQIDGGQMDGNQTDGNQTADNLTGDWYFFSIPF
EANNTSVEYLLSDVNYTSLIYYNASTKLFEEVTEIEPLKGYWINVPDGTGFNASEQFSSVEKKQIEAPPSLQVYPGWNAL
GSPVNETVPAEAAFIALNNSYAKIVGPWVPGNNTTGYYQYVGYNGLNGTIGENQLGADEFEVEPYEGYWVFIRQENLYA
>Mature_718_residues
SVLEGIEGIRNNNETGESWFVYINGTQAGEDFGMNPVSNGTNLSFWYTDEENGVAALDNATYLANITVAIEELEEPAEEN
DIIETATEAGNFSTLLTAIEAANLTDTLKGEGPFTVFAPTDEAFSALPNGTIEALLNDTDALTNILLYHVADERLMAEDV
VNLTNITTLQGGELPVNVTEEGVFVGEAEIIVQDVNASNGVIHVIDAVLIPEEGMEPEPEPGQNVTELYNDTVSLTEGNF
TLMPENSTESYAINNFTDIGALNAAGLDFNVSLMQNMTGNAANMTAVPFTLQSVEGIRNNNTTGEEWFLYINGEPAEEDF
GMNNVSAGDNLSFWYTTEKGGEAAVENASYVANITVSELRANANIIPAAQNQTNLTVFVDAVQTANLTQTLDGTGPYTVC
IPSDEAFNKLPEGTRNQLMNNTTLLNQVLSYHVVSGRYTYEQLIGMNNITNIQGNVLQVNAIGNNITIQNVSVTQIIVVN
NGVICIIDEVLIPPDGEIPADNQTDGGQIDDNQTDGGQMDGNQTDGDQIDGGQMDGNQTDGNQTADNLTGDWYFFSIPFE
ANNTSVEYLLSDVNYTSLIYYNASTKLFEEVTEIEPLKGYWINVPDGTGFNASEQFSSVEKKQIEAPPSLQVYPGWNALG
SPVNETVPAEAAFIALNNSYAKIVGPWVPGNNTTGYYQYVGYNGLNGTIGENQLGADEFEVEPYEGYWVFIRQENLYA

Specific function: Unknown

COG id: COG2335

COG function: function code M; Secreted and surface protein containing fasciclin-like repeats

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAS1 domain [H]

Homologues:

Organism=Homo sapiens, GI4507467, Length=416, Percent_Identity=26.2019230769231, Blast_Score=122, Evalue=2e-27,
Organism=Homo sapiens, GI209862911, Length=419, Percent_Identity=22.673031026253, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI209863034, Length=419, Percent_Identity=22.673031026253, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI209863011, Length=419, Percent_Identity=22.673031026253, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI209862907, Length=421, Percent_Identity=22.8028503562945, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI61743978, Length=134, Percent_Identity=37.3134328358209, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI61743980, Length=130, Percent_Identity=36.1538461538462, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28574452, Length=150, Percent_Identity=29.3333333333333, Blast_Score=68, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000782 [H]

Pfam domain/function: PF02469 Fasciclin [H]

EC number: NA

Molecular weight: Translated: 77892; Mature: 77761

Theoretical pI: Translated: 3.35; Mature: 3.35

Prosite motif: PS50213 FAS1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLEGIEGIRNNNETGESWFVYINGTQAGEDFGMNPVSNGTNLSFWYTDEENGVAALDN
CCHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEECC
ATYLANITVAIEELEEPAEENDIIETATEAGNFSTLLTAIEAANLTDTLKGEGPFTVFAP
CEEEEEEEEEEEHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHCCCCHHHCCCCCEEEECC
TDEAFSALPNGTIEALLNDTDALTNILLYHVADERLMAEDVVNLTNITTLQGGELPVNVT
CHHHHHHCCCCCEEEEECCHHHHHHEEEEEECCCHHHHHHHHHHHEEEEECCCCEEEEEC
EEGVFVGEAEIIVQDVNASNGVIHVIDAVLIPEEGMEPEPEPGQNVTELYNDTVSLTEGN
CCCEEEECEEEEEEECCCCCCEEEEEEEEEECCCCCCCCCCCCCCHHHHHCCEEEEECCC
FTLMPENSTESYAINNFTDIGALNAAGLDFNVSLMQNMTGNAANMTAVPFTLQSVEGIRN
EEEEECCCCCCEEECCCCCCCCCCCCCCCEEHHHHHCCCCCCCCEEEEEEEHHHHHCCCC
NNTTGEEWFLYINGEPAEEDFGMNNVSAGDNLSFWYTTEKGGEAAVENASYVANITVSEL
CCCCCCEEEEEECCCCCHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEEEHHHH
RANANIIPAAQNQTNLTVFVDAVQTANLTQTLDGTGPYTVCIPSDEAFNKLPEGTRNQLM
HCCCCEEECCCCCCCEEEEEEEECCCCCEEECCCCCCEEEEECCCHHHHHCCCCHHHHHH
NNTTLLNQVLSYHVVSGRYTYEQLIGMNNITNIQGNVLQVNAIGNNITIQNVSVTQIIVV
CCHHHHHHHHHHEEECCCEEHHHHHCCCCCCCCCCCEEEEEECCCEEEEEEEEEEEEEEE
NNGVICIIDEVLIPPDGEIPADNQTDGGQIDDNQTDGGQMDGNQTDGDQIDGGQMDGNQT
CCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DGNQTADNLTGDWYFFSIPFEANNTSVEYLLSDVNYTSLIYYNASTKLFEEVTEIEPLKG
CCCCCCCCCCCCEEEEEEEECCCCCEEEEEEECCCEEEEEEECCCHHHHHHHHHCCCCCC
YWINVPDGTGFNASEQFSSVEKKQIEAPPSLQVYPGWNALGSPVNETVPAEAAFIALNNS
EEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCHHCCCCCCCCCCCCEEEEEECCC
YAKIVGPWVPGNNTTGYYQYVGYNGLNGTIGENQLGADEFEVEPYEGYWVFIRQENLYA
EEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEECCCCCEEEEEECCCCCC
>Mature Secondary Structure 
SVLEGIEGIRNNNETGESWFVYINGTQAGEDFGMNPVSNGTNLSFWYTDEENGVAALDN
CHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEECC
ATYLANITVAIEELEEPAEENDIIETATEAGNFSTLLTAIEAANLTDTLKGEGPFTVFAP
CEEEEEEEEEEEHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHCCCCHHHCCCCCEEEECC
TDEAFSALPNGTIEALLNDTDALTNILLYHVADERLMAEDVVNLTNITTLQGGELPVNVT
CHHHHHHCCCCCEEEEECCHHHHHHEEEEEECCCHHHHHHHHHHHEEEEECCCCEEEEEC
EEGVFVGEAEIIVQDVNASNGVIHVIDAVLIPEEGMEPEPEPGQNVTELYNDTVSLTEGN
CCCEEEECEEEEEEECCCCCCEEEEEEEEEECCCCCCCCCCCCCCHHHHHCCEEEEECCC
FTLMPENSTESYAINNFTDIGALNAAGLDFNVSLMQNMTGNAANMTAVPFTLQSVEGIRN
EEEEECCCCCCEEECCCCCCCCCCCCCCCEEHHHHHCCCCCCCCEEEEEEEHHHHHCCCC
NNTTGEEWFLYINGEPAEEDFGMNNVSAGDNLSFWYTTEKGGEAAVENASYVANITVSEL
CCCCCCEEEEEECCCCCHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEEEHHHH
RANANIIPAAQNQTNLTVFVDAVQTANLTQTLDGTGPYTVCIPSDEAFNKLPEGTRNQLM
HCCCCEEECCCCCCCEEEEEEEECCCCCEEECCCCCCEEEEECCCHHHHHCCCCHHHHHH
NNTTLLNQVLSYHVVSGRYTYEQLIGMNNITNIQGNVLQVNAIGNNITIQNVSVTQIIVV
CCHHHHHHHHHHEEECCCEEHHHHHCCCCCCCCCCCEEEEEECCCEEEEEEEEEEEEEEE
NNGVICIIDEVLIPPDGEIPADNQTDGGQIDDNQTDGGQMDGNQTDGDQIDGGQMDGNQT
CCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DGNQTADNLTGDWYFFSIPFEANNTSVEYLLSDVNYTSLIYYNASTKLFEEVTEIEPLKG
CCCCCCCCCCCCEEEEEEEECCCCCEEEEEEECCCEEEEEEECCCHHHHHHHHHCCCCCC
YWINVPDGTGFNASEQFSSVEKKQIEAPPSLQVYPGWNALGSPVNETVPAEAAFIALNNS
EEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCHHCCCCCCCCCCCCEEEEEECCC
YAKIVGPWVPGNNTTGYYQYVGYNGLNGTIGENQLGADEFEVEPYEGYWVFIRQENLYA
EEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEECCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]