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The map label for this gene is trkG [H]

Identifier: 21228604

GI number: 21228604

Start: 2982304

End: 2983734

Strand: Reverse

Name: trkG [H]

Synonym: MM_2502

Alternate gene names: 21228604

Gene position: 2983734-2982304 (Counterclockwise)

Preceding gene: 21228605

Following gene: 21228603

Centisome position: 72.84

GC content: 45.14

Gene sequence:

>1431_bases
GTGAATAAAAAAGCTATTTATAATGCGCTTGGGAAAATTCTTATACTTCTGGCTTTTACAATGCTCGTTCCTCTTTTAGT
GGCTTTTTATTATGGGGAACCTCTGAAACCGTTTACGGTTTCCATTCTCATAACCTTTCTTGCCGGTTTGCTCCTTACAC
GCATCAAGAGCAGTGCTGAATGGCAGCAGAAAGAAGCCCTTGCCATTGTGGCTCTGACCTGGCTTTCAGCAGCTATTTTT
GGAGGGATCCCTTTCCTTTTCGAGGGCGTATCCTTCATTGATGCCGTGTTTGAAACAATGTCGGGTTTCACGTCAACGGG
TTCGACTATTTTTGTGGATATTGAGAGTTATTCCAGGAGTCTTCTTTTCTGGCGTTCTTTTACGCAGTGGCTGGGCGGTA
TGGGTATTATTGTGCTTTTCATTGCTATCCTGCCAAAACTCGGAGTTGCGGGGCGCCAGCTTTTCCGGGCAGAAGCTCCG
GGCCCTACAGAAGATAAGCTCAAGCCAAGGATAAAAGATACGGCAAAGATCCTGTGGGCGCTTTATGTCCTGATCTCTGC
CGTTGAAGTTGTGGCACTGATGCTTGCAGGAATGTCCCTGTATGACGCCCTCACGCACACTTTTGCAGGCATGGCATGTG
GAGGCTATTCCCCTTATGGTCTGGGGATTGAAGCTTTTAACAGCCCTCTTATAGAATTTATTCTCACATTTTTTATGTTC
GCAGCCGGAGCGAACTTTGCCCTGTATTACAGGGCGATTTTTATTGACAGTAACTTTCTTCTTAAAGATGAGGAGTTCAG
GGCTTATACCTTTATTCTCCTGGGATTTTCAGGCCTTCTCACCCTGGTTCTGTACAAAGATATGGATTTTTCCCTTTTCA
ATTCTTTCCGTTACGCCATATTCCAGATTACCTCTATCATGACGGCTACGGGCTTTGCTTCAACTGATTTTAACCTCTGG
ACAGATTCGGCAAAGGTCCTGGTTTTTGCGGTCATGTTTATAGGCGGCTGTGCAGGCTCCACCGGGGGAGGCATGAAGGT
CGTGCGTTTTCTGCTGATGTTAAAGTATGCGAGGAGAGAGCTGTTTAAATTTGTTCATCCAAGGCTTATAAGGCCCATCA
GATTCAATAACAAAGCAGTGCCTGATGATGTTTTACAGTCCATCCTGTCCTTTGTTGTGATTTACATATTAGTTTTTATC
TTCAGTGCAATGTTCCTGACTCTGCTTGGAGTCGACATGATCAGTTCTGCTACCGCTTCGATTGCAACCCTTGGAAATAT
AGGACCTGGTTTTAACGTAGTCGGACCTATGGCAAACTTTTCAGCACTCCCTCCCCTGGGAAAAATTATCCTGATAAATA
ATATGTGGGTCGGAAGGCTTGAGGTTTATACCGTACTGGTACTCTTCACAAGCGATTTCTGGCATTCCTGA

Upstream 100 bases:

>100_bases
GTGTAGTTATTTTCTCAATGGCTTCGGCAGCATCGGAAGTAGAAAAATATTTCAAGTAAGAAAATATTTCAAGTAAGTTT
TACGGGACAGGGGTTTTTCT

Downstream 100 bases:

>100_bases
ACAAAATTTCATTAAAGGCATACAATAGATGTGCCTGAAGTTGTCAGGCATCTGTGTTTTCCACTCATGCTTTTCCTGTA
AATGCACCTGAATTCAGTCT

Product: Trk system potassium uptake protein

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MNKKAIYNALGKILILLAFTMLVPLLVAFYYGEPLKPFTVSILITFLAGLLLTRIKSSAEWQQKEALAIVALTWLSAAIF
GGIPFLFEGVSFIDAVFETMSGFTSTGSTIFVDIESYSRSLLFWRSFTQWLGGMGIIVLFIAILPKLGVAGRQLFRAEAP
GPTEDKLKPRIKDTAKILWALYVLISAVEVVALMLAGMSLYDALTHTFAGMACGGYSPYGLGIEAFNSPLIEFILTFFMF
AAGANFALYYRAIFIDSNFLLKDEEFRAYTFILLGFSGLLTLVLYKDMDFSLFNSFRYAIFQITSIMTATGFASTDFNLW
TDSAKVLVFAVMFIGGCAGSTGGGMKVVRFLLMLKYARRELFKFVHPRLIRPIRFNNKAVPDDVLQSILSFVVIYILVFI
FSAMFLTLLGVDMISSATASIATLGNIGPGFNVVGPMANFSALPPLGKIILINNMWVGRLEVYTVLVLFTSDFWHS

Sequences:

>Translated_476_residues
MNKKAIYNALGKILILLAFTMLVPLLVAFYYGEPLKPFTVSILITFLAGLLLTRIKSSAEWQQKEALAIVALTWLSAAIF
GGIPFLFEGVSFIDAVFETMSGFTSTGSTIFVDIESYSRSLLFWRSFTQWLGGMGIIVLFIAILPKLGVAGRQLFRAEAP
GPTEDKLKPRIKDTAKILWALYVLISAVEVVALMLAGMSLYDALTHTFAGMACGGYSPYGLGIEAFNSPLIEFILTFFMF
AAGANFALYYRAIFIDSNFLLKDEEFRAYTFILLGFSGLLTLVLYKDMDFSLFNSFRYAIFQITSIMTATGFASTDFNLW
TDSAKVLVFAVMFIGGCAGSTGGGMKVVRFLLMLKYARRELFKFVHPRLIRPIRFNNKAVPDDVLQSILSFVVIYILVFI
FSAMFLTLLGVDMISSATASIATLGNIGPGFNVVGPMANFSALPPLGKIILINNMWVGRLEVYTVLVLFTSDFWHS
>Mature_476_residues
MNKKAIYNALGKILILLAFTMLVPLLVAFYYGEPLKPFTVSILITFLAGLLLTRIKSSAEWQQKEALAIVALTWLSAAIF
GGIPFLFEGVSFIDAVFETMSGFTSTGSTIFVDIESYSRSLLFWRSFTQWLGGMGIIVLFIAILPKLGVAGRQLFRAEAP
GPTEDKLKPRIKDTAKILWALYVLISAVEVVALMLAGMSLYDALTHTFAGMACGGYSPYGLGIEAFNSPLIEFILTFFMF
AAGANFALYYRAIFIDSNFLLKDEEFRAYTFILLGFSGLLTLVLYKDMDFSLFNSFRYAIFQITSIMTATGFASTDFNLW
TDSAKVLVFAVMFIGGCAGSTGGGMKVVRFLLMLKYARRELFKFVHPRLIRPIRFNNKAVPDDVLQSILSFVVIYILVFI
FSAMFLTLLGVDMISSATASIATLGNIGPGFNVVGPMANFSALPPLGKIILINNMWVGRLEVYTVLVLFTSDFWHS

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=485, Percent_Identity=40.6185567010309, Blast_Score=301, Evalue=4e-83,
Organism=Escherichia coli, GI1787626, Length=483, Percent_Identity=32.5051759834368, Blast_Score=270, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 52680; Mature: 52680

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKAIYNALGKILILLAFTMLVPLLVAFYYGEPLKPFTVSILITFLAGLLLTRIKSSAE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
WQQKEALAIVALTWLSAAIFGGIPFLFEGVSFIDAVFETMSGFTSTGSTIFVDIESYSRS
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHH
LLFWRSFTQWLGGMGIIVLFIAILPKLGVAGRQLFRAEAPGPTEDKLKPRIKDTAKILWA
HHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHH
LYVLISAVEVVALMLAGMSLYDALTHTFAGMACGGYSPYGLGIEAFNSPLIEFILTFFMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHH
AAGANFALYYRAIFIDSNFLLKDEEFRAYTFILLGFSGLLTLVLYKDMDFSLFNSFRYAI
HCCCCCEEEEEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FQITSIMTATGFASTDFNLWTDSAKVLVFAVMFIGGCAGSTGGGMKVVRFLLMLKYARRE
HHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
LFKFVHPRLIRPIRFNNKAVPDDVLQSILSFVVIYILVFIFSAMFLTLLGVDMISSATAS
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IATLGNIGPGFNVVGPMANFSALPPLGKIILINNMWVGRLEVYTVLVLFTSDFWHS
HHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKKAIYNALGKILILLAFTMLVPLLVAFYYGEPLKPFTVSILITFLAGLLLTRIKSSAE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
WQQKEALAIVALTWLSAAIFGGIPFLFEGVSFIDAVFETMSGFTSTGSTIFVDIESYSRS
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHH
LLFWRSFTQWLGGMGIIVLFIAILPKLGVAGRQLFRAEAPGPTEDKLKPRIKDTAKILWA
HHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHH
LYVLISAVEVVALMLAGMSLYDALTHTFAGMACGGYSPYGLGIEAFNSPLIEFILTFFMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHH
AAGANFALYYRAIFIDSNFLLKDEEFRAYTFILLGFSGLLTLVLYKDMDFSLFNSFRYAI
HCCCCCEEEEEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FQITSIMTATGFASTDFNLWTDSAKVLVFAVMFIGGCAGSTGGGMKVVRFLLMLKYARRE
HHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
LFKFVHPRLIRPIRFNNKAVPDDVLQSILSFVVIYILVFIFSAMFLTLLGVDMISSATAS
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IATLGNIGPGFNVVGPMANFSALPPLGKIILINNMWVGRLEVYTVLVLFTSDFWHS
HHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]