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The map label for this gene is trkG [H]

Identifier: 21228602

GI number: 21228602

Start: 2979085

End: 2980515

Strand: Reverse

Name: trkG [H]

Synonym: MM_2500

Alternate gene names: 21228602

Gene position: 2980515-2979085 (Counterclockwise)

Preceding gene: 21228603

Following gene: 21228593

Centisome position: 72.76

GC content: 45.0

Gene sequence:

>1431_bases
ATGAATATTAAGATTGTTTTTTATGTGCTTGGCGGTTTACTCAGGCTTCTCGGGATAATCATGGTTGTTCCTCTCGGAGT
TGCGTACTACTATGGAGAAGATCTGACTCCGTTTCTTGTATCTATAGCAATAACCGTTATTACAGGCCTGATCCTTCTTT
CCTACAAAACTGATGAAGAATGGATGCGCAAAGAAGGCTTTGCAATCGTTGGACTGGGCTGGCTTATTGCTGCGGTTTTT
GGAGCAATCCCTTTTGTGCTTGACGGGATTTCCCCGCTTAACGCCCTTTTTGAATCCATGTCAGCCTTTACCACCACAGG
CTCGACAATCCTCACGGATATAGAAAGCCACCCTAAAGGAATCCTTTTCTGGCGAGGCATGATGCAGTGGCTTGGCGGTA
TGGGAATTATCGTGCTTTTCATAGCCATTCTGCCAAAACTCGGAGTTGCAGGCAGACAGCTCTTCCGGGCTGAAGCCCCT
GGCCCAACAGAAGATAAGCTGAAACCAAGAATCAGGGAAACAGCAAAGATCCTGTGGATGGTTTACTTCGTAATCTCATT
CGCCCAGGTAGTTACCCTTCTGCTCGCAGGTCTTTCGCTGTACGATGCGGTAAACCATACATTTACCACGATGGCCTGCG
GAGGTTTCTCCAATTACGGGTTGAGTATTGGTGCTTTTAACAGTCCTCTTGTTGAGTATATAATAACTTTTTTCACTTTC
GTTGCCGGTGCAAACTTTGCACTCCATTACAGGGCGATTTATGTTGACAGGGACTTCCTGCTTAAAGACGATGAGTTCCG
TTTCTATACAGCTCTGGTCCTGTCAGCAAGCGGGCTCCTTACTCTTCTGCTATGGAGGGACCTTAATACTGGCTTTTTTG
ATTCATTCCGGCTTGCAATCTTTCATGTAGTTACGATAATGACAAGTACCGGGTTTGCAATAGCTGATTTTAATCTCTGG
TCAGAATCTTCAAAAATGGTGATTCTTTTAGTTATGTTTATTGGAGGCTGTGCAGGTTCTACAGGTGGAGGCATCAAGGT
TGTACGCATTCTTATCTTACTCAGACACAGCCGAACGGAATTGTTCAAGGCTCTTCACCCCAGAGCCATAAAAAGCGTTA
AATTCAACAATAAAGCCGTGCCTGATGAGATTATCAGCTCTATAATCTCATTTGTGGTGATTTACCTCCTTATTTTTATC
TCAAGCGCCCTTATCCTCTCTGTCCTGGGAATGGACATCATAACTTCAATTACAGCTTCCATTGCTACCCTGGGCAACAT
AGGTCCGGGCCTGGGTGTGGTAGGTCCTATGGGTTCTTTTGACCCCATTCCTCCCCTGGGAAAATTAATCCTGATCGCCA
ATATGTGGATTGGGAGGCTTGAAATCTACACGGTAATCGTGCTCTTTACTCCTGAGTTCTGGAATAAATAA

Upstream 100 bases:

>100_bases
ATCTGTCCCTCATTTTTGAGAAGCTGTTTAAGCAAGAAATAAATATGAATAGTCATGAGTAGATTGAAAGAGTCATCACC
TGTAAAAATAGAGGATCGGC

Downstream 100 bases:

>100_bases
TTCCATGAAAAAAACCAAGATGCCTGGAAAAAGTAAAATTTAGAAAAACAGGATTTGCAGACAGAACCCCTGCAGGAAAT
CTAAAGTAGACCAGAAAAAA

Product: Trk system potassium uptake protein

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MNIKIVFYVLGGLLRLLGIIMVVPLGVAYYYGEDLTPFLVSIAITVITGLILLSYKTDEEWMRKEGFAIVGLGWLIAAVF
GAIPFVLDGISPLNALFESMSAFTTTGSTILTDIESHPKGILFWRGMMQWLGGMGIIVLFIAILPKLGVAGRQLFRAEAP
GPTEDKLKPRIRETAKILWMVYFVISFAQVVTLLLAGLSLYDAVNHTFTTMACGGFSNYGLSIGAFNSPLVEYIITFFTF
VAGANFALHYRAIYVDRDFLLKDDEFRFYTALVLSASGLLTLLLWRDLNTGFFDSFRLAIFHVVTIMTSTGFAIADFNLW
SESSKMVILLVMFIGGCAGSTGGGIKVVRILILLRHSRTELFKALHPRAIKSVKFNNKAVPDEIISSIISFVVIYLLIFI
SSALILSVLGMDIITSITASIATLGNIGPGLGVVGPMGSFDPIPPLGKLILIANMWIGRLEIYTVIVLFTPEFWNK

Sequences:

>Translated_476_residues
MNIKIVFYVLGGLLRLLGIIMVVPLGVAYYYGEDLTPFLVSIAITVITGLILLSYKTDEEWMRKEGFAIVGLGWLIAAVF
GAIPFVLDGISPLNALFESMSAFTTTGSTILTDIESHPKGILFWRGMMQWLGGMGIIVLFIAILPKLGVAGRQLFRAEAP
GPTEDKLKPRIRETAKILWMVYFVISFAQVVTLLLAGLSLYDAVNHTFTTMACGGFSNYGLSIGAFNSPLVEYIITFFTF
VAGANFALHYRAIYVDRDFLLKDDEFRFYTALVLSASGLLTLLLWRDLNTGFFDSFRLAIFHVVTIMTSTGFAIADFNLW
SESSKMVILLVMFIGGCAGSTGGGIKVVRILILLRHSRTELFKALHPRAIKSVKFNNKAVPDEIISSIISFVVIYLLIFI
SSALILSVLGMDIITSITASIATLGNIGPGLGVVGPMGSFDPIPPLGKLILIANMWIGRLEIYTVIVLFTPEFWNK
>Mature_476_residues
MNIKIVFYVLGGLLRLLGIIMVVPLGVAYYYGEDLTPFLVSIAITVITGLILLSYKTDEEWMRKEGFAIVGLGWLIAAVF
GAIPFVLDGISPLNALFESMSAFTTTGSTILTDIESHPKGILFWRGMMQWLGGMGIIVLFIAILPKLGVAGRQLFRAEAP
GPTEDKLKPRIRETAKILWMVYFVISFAQVVTLLLAGLSLYDAVNHTFTTMACGGFSNYGLSIGAFNSPLVEYIITFFTF
VAGANFALHYRAIYVDRDFLLKDDEFRFYTALVLSASGLLTLLLWRDLNTGFFDSFRLAIFHVVTIMTSTGFAIADFNLW
SESSKMVILLVMFIGGCAGSTGGGIKVVRILILLRHSRTELFKALHPRAIKSVKFNNKAVPDEIISSIISFVVIYLLIFI
SSALILSVLGMDIITSITASIATLGNIGPGLGVVGPMGSFDPIPPLGKLILIANMWIGRLEIYTVIVLFTPEFWNK

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=488, Percent_Identity=40.9836065573771, Blast_Score=309, Evalue=3e-85,
Organism=Escherichia coli, GI1787626, Length=489, Percent_Identity=34.7648261758691, Blast_Score=284, Evalue=7e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 52284; Mature: 52284

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKIVFYVLGGLLRLLGIIMVVPLGVAYYYGEDLTPFLVSIAITVITGLILLSYKTDEE
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
WMRKEGFAIVGLGWLIAAVFGAIPFVLDGISPLNALFESMSAFTTTGSTILTDIESHPKG
HHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCH
ILFWRGMMQWLGGMGIIVLFIAILPKLGVAGRQLFRAEAPGPTEDKLKPRIRETAKILWM
HHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHCHHHHHHHHHHHH
VYFVISFAQVVTLLLAGLSLYDAVNHTFTTMACGGFSNYGLSIGAFNSPLVEYIITFFTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHH
VAGANFALHYRAIYVDRDFLLKDDEFRFYTALVLSASGLLTLLLWRDLNTGFFDSFRLAI
HHCCCEEEEEEEEEEECCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
FHVVTIMTSTGFAIADFNLWSESSKMVILLVMFIGGCAGSTGGGIKVVRILILLRHSRTE
HHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
LFKALHPRAIKSVKFNNKAVPDEIISSIISFVVIYLLIFISSALILSVLGMDIITSITAS
HHHHHCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IATLGNIGPGLGVVGPMGSFDPIPPLGKLILIANMWIGRLEIYTVIVLFTPEFWNK
HHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEEEECCHHCCC
>Mature Secondary Structure
MNIKIVFYVLGGLLRLLGIIMVVPLGVAYYYGEDLTPFLVSIAITVITGLILLSYKTDEE
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
WMRKEGFAIVGLGWLIAAVFGAIPFVLDGISPLNALFESMSAFTTTGSTILTDIESHPKG
HHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCH
ILFWRGMMQWLGGMGIIVLFIAILPKLGVAGRQLFRAEAPGPTEDKLKPRIRETAKILWM
HHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHCHHHHHHHHHHHH
VYFVISFAQVVTLLLAGLSLYDAVNHTFTTMACGGFSNYGLSIGAFNSPLVEYIITFFTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHH
VAGANFALHYRAIYVDRDFLLKDDEFRFYTALVLSASGLLTLLLWRDLNTGFFDSFRLAI
HHCCCEEEEEEEEEEECCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
FHVVTIMTSTGFAIADFNLWSESSKMVILLVMFIGGCAGSTGGGIKVVRILILLRHSRTE
HHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
LFKALHPRAIKSVKFNNKAVPDEIISSIISFVVIYLLIFISSALILSVLGMDIITSITAS
HHHHHCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IATLGNIGPGLGVVGPMGSFDPIPPLGKLILIANMWIGRLEIYTVIVLFTPEFWNK
HHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]