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The map label for this gene is fpoA [H]

Identifier: 21228593

GI number: 21228593

Start: 2968855

End: 2969244

Strand: Reverse

Name: fpoA [H]

Synonym: MM_2491

Alternate gene names: 21228593

Gene position: 2969244-2968855 (Counterclockwise)

Preceding gene: 21228602

Following gene: 21228592

Centisome position: 72.49

GC content: 42.31

Gene sequence:

>390_bases
TTGATAGGTGATACAATGTCTGGAATAATTGATAGCTATATACCGGTTGCCATATTTCTTGCCGTGGGACTGATCATGCC
TCCCATGACAATGTTCATGGTAAAACAACTGAGTCCGAGGAGCAAAGCAGCCAGCAAATACACAACATACGAGTCGGGTT
CCGTTCCAACAGGAACTGCAAGGATCCAGTTCAATGTTGAGTATTATCTCTATGCAATTGCTTTCGTTCTTTTTGATATT
GAGGTGCTTTTCCTTTACCCTTGGGCTACAGTCTATAAGGGGCATGGGATTACCTCAATTGCAGTGGTTGAAATGTTTGT
ATTCATTTTCATACTGCTCTTCGGATATGTATATCTCTGGAAGAAGGAGGCCCTTACATGGGTGAAGTGA

Upstream 100 bases:

>100_bases
GGTTTGTAAATAACCGGAAGATTCGGACAGTCTTTTTGTCCAGCATCTTAAAAATTAAAAATTAAAATCATGCAACGCTG
CAATTTCAGATTGCTGCACT

Downstream 100 bases:

>100_bases
AGGAGACAAAAACGAATAACTCAAAGGAAAACCCGGAAGAAGAAGTCCCCGGAGTCATCACAACAACTACAAGTGCAATC
CACAATTTCCTCAAGAAAAC

Product: F420H2 dehydrogenase subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1 [H]

Number of amino acids: Translated: 129; Mature: 129

Protein sequence:

>129_residues
MIGDTMSGIIDSYIPVAIFLAVGLIMPPMTMFMVKQLSPRSKAASKYTTYESGSVPTGTARIQFNVEYYLYAIAFVLFDI
EVLFLYPWATVYKGHGITSIAVVEMFVFIFILLFGYVYLWKKEALTWVK

Sequences:

>Translated_129_residues
MIGDTMSGIIDSYIPVAIFLAVGLIMPPMTMFMVKQLSPRSKAASKYTTYESGSVPTGTARIQFNVEYYLYAIAFVLFDI
EVLFLYPWATVYKGHGITSIAVVEMFVFIFILLFGYVYLWKKEALTWVK
>Mature_129_residues
MIGDTMSGIIDSYIPVAIFLAVGLIMPPMTMFMVKQLSPRSKAASKYTTYESGSVPTGTARIQFNVEYYLYAIAFVLFDI
EVLFLYPWATVYKGHGITSIAVVEMFVFIFILLFGYVYLWKKEALTWVK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788625, Length=124, Percent_Identity=36.2903225806452, Blast_Score=77, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 14668; Mature: 14668

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGDTMSGIIDSYIPVAIFLAVGLIMPPMTMFMVKQLSPRSKAASKYTTYESGSVPTGTA
CCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCE
RIQFNVEYYLYAIAFVLFDIEVLFLYPWATVYKGHGITSIAVVEMFVFIFILLFGYVYLW
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KKEALTWVK
HHHHHHCCC
>Mature Secondary Structure
MIGDTMSGIIDSYIPVAIFLAVGLIMPPMTMFMVKQLSPRSKAASKYTTYESGSVPTGTA
CCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCE
RIQFNVEYYLYAIAFVLFDIEVLFLYPWATVYKGHGITSIAVVEMFVFIFILLFGYVYLW
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KKEALTWVK
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA