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The map label for this gene is infB [H]

Identifier: 21228565

GI number: 21228565

Start: 2937898

End: 2939673

Strand: Reverse

Name: infB [H]

Synonym: MM_2463

Alternate gene names: 21228565

Gene position: 2939673-2937898 (Counterclockwise)

Preceding gene: 21228566

Following gene: 21228564

Centisome position: 71.76

GC content: 47.92

Gene sequence:

>1776_bases
ATGACCGACAAGAAAAACCTAAGGACTCCTATAGTCTGCGTGATGGGGCACGTTGACCACGGGAAAACCACCCTGCTTGA
CAAGATCAGAGGCACTGCGATTGTCAGCGGGGAAGCCGGTGCTATTACTCAGCACATAGGAGCAACCGAAGTCCCTATAG
ATGTGATTATCGATAAGCTCGGAGACCCCAGGCTCAGGGACCGCTTTATGGTACCGGGGCTGCTTTTTATTGATACTCCG
GGGCATCACGCTTTTACAACCCTCAGGAGCAGAGGAGGCGCACTTGCCGACCTCGCAATTGTGGTCGTTGACATAAACGA
AGGTTTCAAGCCCCAGACCTACGAGAGCTTGCAGATCTTAAAGCGGTTCAAGACTCCTTTTGTTGTCGTTGCCAATAAAA
TCGACAGGATAGGCGGCTGGGTTTCACAGAAAGACATGCCTTTTGCTGCTACTTTCAAGAAGCAGTCCAGTGATGTCCAG
GCACGGCTTGAAACAAAGCTCTACGAGGTAATAGGTGAACTTTACAACCAGGGGTTTGCAGCAGAACGCTACGACAGGGT
CACAAACTTCCAGAAAACCCTTGGAGTAGTTCCTGTAAGCGCTTTTACAGGGGAAGGTATTCCTGATGTCCTTATGGTGC
TTCTGGGTCTTGCCCAGAAATTCCTTGAGGCAAACCTGCAGTACAGCGCCAAAGGTCCGGGAGTAGGGACTGTCCTTGAG
GTAAAAGAAGAAAAAGGACTCGGAGCAACCCTTGATATTATCCTTTACGACGGTACATTGAAGAAAGGAGATACTGTTGT
TATCGGTAGCCTTGGCGAGCCAATCCGGACAAAGGTAAGGGCTCTTTTAAAGCCGAGAGAACTTTCCGAAATCCGTTACG
AGAGCAAGTTCCAGCAGGTGAGTAAAGTAACTGCTGCGGCTGGTGTTAAGATTTCGGCTCCTGGCCTTGAAGGCGCACTT
GCAGGCTCTCCCATAAGGGTTGCAACGGAAGATAACCTTGAAGAAATTGCATCCCAGGTAAAGTCCGAGATTGATGAGGT
AAGGATTGATACGGGTTCGGTAGGGATCATGATTAAGGCTGATACCCTCGGTTCCCTTGAAGCCCTTGTCCATGAGTTCC
AGAAAGATGAAGTCCCTATCAGGAAAGCTGAAGTAGGAGACATTTCCCACAGGGATGCGGTTGAGGCTTCGACAGTTGAA
GACCCCCTTTACTCGGTGATTATAGGTTTCAATGTTAAGGTTCACCCTGATGCCAGAGATTTCCTGCAGGAAAGCAGTGT
AAAGGTGTTCACAAGTGACGTTATTTACCGTCTGGTTGAAGATTACCAGAAATACGTCAAAGAACAGCAGGAAAAGGCTG
AAAAGAAGATTTTCGAAACAATAATCCGTCCCGGAAAGTTCAAAATCCTTCCAGGATGTGTTTTCCGGCAGAGCAAACCT
GCAGTTGTCGGGGTAAGAGTGCTTGGGGGAGTTGTTCGGACAAATACGGATGTTATGCTTGAAAACGGAAACGTTGTGGG
CAAGATCAAAGGTCTGCAGTCCGAAGGGGAAAATATTCCCTCTGCAAAGGTAGGCAAGGAAGTTGCAATGGCAATTGAAG
GTGCAACCGTAGGCAGGCAGATCAAAGAAGAAGATGTGCTCTACGTTAATGTGCCTGAAAGGCATGCCAAAGTCCTTGAG
CACGAAATCTATGAGTCCCTTTCAACCGATGAAAAGGAAACCCTTGATATTTTCCTGACACTTAAAAGGAAAGACAATCC
TTTCTGGGCAAAGTAA

Upstream 100 bases:

>100_bases
CATTTGTTTATCCTTACCTGCAAAATGGGTCCTTCCGGGGAAACCTGGGCCCTTCTGGACCTGCAGCAAATAAGAAGCGG
GAATGAGAGAGGTTCTGTAT

Downstream 100 bases:

>100_bases
AGGCTGATATGCAGGCAGAGCATATTCAGGATGCAGCAGGACGGGTAAGAATTCCGGATAACTCAGATAAAAAGCAAGGT
AAAGGAATTATTAAAAATAA

Product: translation initiation factor IF-2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 591; Mature: 590

Protein sequence:

>591_residues
MTDKKNLRTPIVCVMGHVDHGKTTLLDKIRGTAIVSGEAGAITQHIGATEVPIDVIIDKLGDPRLRDRFMVPGLLFIDTP
GHHAFTTLRSRGGALADLAIVVVDINEGFKPQTYESLQILKRFKTPFVVVANKIDRIGGWVSQKDMPFAATFKKQSSDVQ
ARLETKLYEVIGELYNQGFAAERYDRVTNFQKTLGVVPVSAFTGEGIPDVLMVLLGLAQKFLEANLQYSAKGPGVGTVLE
VKEEKGLGATLDIILYDGTLKKGDTVVIGSLGEPIRTKVRALLKPRELSEIRYESKFQQVSKVTAAAGVKISAPGLEGAL
AGSPIRVATEDNLEEIASQVKSEIDEVRIDTGSVGIMIKADTLGSLEALVHEFQKDEVPIRKAEVGDISHRDAVEASTVE
DPLYSVIIGFNVKVHPDARDFLQESSVKVFTSDVIYRLVEDYQKYVKEQQEKAEKKIFETIIRPGKFKILPGCVFRQSKP
AVVGVRVLGGVVRTNTDVMLENGNVVGKIKGLQSEGENIPSAKVGKEVAMAIEGATVGRQIKEEDVLYVNVPERHAKVLE
HEIYESLSTDEKETLDIFLTLKRKDNPFWAK

Sequences:

>Translated_591_residues
MTDKKNLRTPIVCVMGHVDHGKTTLLDKIRGTAIVSGEAGAITQHIGATEVPIDVIIDKLGDPRLRDRFMVPGLLFIDTP
GHHAFTTLRSRGGALADLAIVVVDINEGFKPQTYESLQILKRFKTPFVVVANKIDRIGGWVSQKDMPFAATFKKQSSDVQ
ARLETKLYEVIGELYNQGFAAERYDRVTNFQKTLGVVPVSAFTGEGIPDVLMVLLGLAQKFLEANLQYSAKGPGVGTVLE
VKEEKGLGATLDIILYDGTLKKGDTVVIGSLGEPIRTKVRALLKPRELSEIRYESKFQQVSKVTAAAGVKISAPGLEGAL
AGSPIRVATEDNLEEIASQVKSEIDEVRIDTGSVGIMIKADTLGSLEALVHEFQKDEVPIRKAEVGDISHRDAVEASTVE
DPLYSVIIGFNVKVHPDARDFLQESSVKVFTSDVIYRLVEDYQKYVKEQQEKAEKKIFETIIRPGKFKILPGCVFRQSKP
AVVGVRVLGGVVRTNTDVMLENGNVVGKIKGLQSEGENIPSAKVGKEVAMAIEGATVGRQIKEEDVLYVNVPERHAKVLE
HEIYESLSTDEKETLDIFLTLKRKDNPFWAK
>Mature_590_residues
TDKKNLRTPIVCVMGHVDHGKTTLLDKIRGTAIVSGEAGAITQHIGATEVPIDVIIDKLGDPRLRDRFMVPGLLFIDTPG
HHAFTTLRSRGGALADLAIVVVDINEGFKPQTYESLQILKRFKTPFVVVANKIDRIGGWVSQKDMPFAATFKKQSSDVQA
RLETKLYEVIGELYNQGFAAERYDRVTNFQKTLGVVPVSAFTGEGIPDVLMVLLGLAQKFLEANLQYSAKGPGVGTVLEV
KEEKGLGATLDIILYDGTLKKGDTVVIGSLGEPIRTKVRALLKPRELSEIRYESKFQQVSKVTAAAGVKISAPGLEGALA
GSPIRVATEDNLEEIASQVKSEIDEVRIDTGSVGIMIKADTLGSLEALVHEFQKDEVPIRKAEVGDISHRDAVEASTVED
PLYSVIIGFNVKVHPDARDFLQESSVKVFTSDVIYRLVEDYQKYVKEQQEKAEKKIFETIIRPGKFKILPGCVFRQSKPA
VVGVRVLGGVVRTNTDVMLENGNVVGKIKGLQSEGENIPSAKVGKEVAMAIEGATVGRQIKEEDVLYVNVPERHAKVLEH
EIYESLSTDEKETLDIFLTLKRKDNPFWAK

Specific function: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 [H]

COG id: COG0532

COG function: function code J; Translation initiation factor 2 (IF-2; GTPase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-2 family [H]

Homologues:

Organism=Homo sapiens, GI84043963, Length=562, Percent_Identity=36.4768683274021, Blast_Score=362, Evalue=1e-100,
Organism=Homo sapiens, GI53729339, Length=269, Percent_Identity=33.457249070632, Blast_Score=136, Evalue=6e-32,
Organism=Homo sapiens, GI53729337, Length=269, Percent_Identity=33.457249070632, Blast_Score=136, Evalue=6e-32,
Organism=Escherichia coli, GI1789559, Length=561, Percent_Identity=29.7682709447415, Blast_Score=159, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI212656558, Length=588, Percent_Identity=36.9047619047619, Blast_Score=360, Evalue=1e-99,
Organism=Caenorhabditis elegans, GI71994658, Length=270, Percent_Identity=32.2222222222222, Blast_Score=119, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6319282, Length=589, Percent_Identity=37.8607809847199, Blast_Score=357, Evalue=2e-99,
Organism=Saccharomyces cerevisiae, GI6324550, Length=588, Percent_Identity=26.1904761904762, Blast_Score=144, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24656849, Length=562, Percent_Identity=36.2989323843416, Blast_Score=356, Evalue=3e-98,
Organism=Drosophila melanogaster, GI28572034, Length=541, Percent_Identity=25.6931608133087, Blast_Score=119, Evalue=7e-27,
Organism=Drosophila melanogaster, GI160714833, Length=85, Percent_Identity=50.5882352941176, Blast_Score=83, Evalue=4e-16,

Paralogues:

None

Copy number: 1150 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR004544
- InterPro:   IPR015760
- InterPro:   IPR023115
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2; PF11987 IF-2 [H]

EC number: NA

Molecular weight: Translated: 64902; Mature: 64770

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKKNLRTPIVCVMGHVDHGKTTLLDKIRGTAIVSGEAGAITQHIGATEVPIDVIIDKL
CCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCEEECCCCCCHHHHCCCCCCCHHHHHHCC
GDPRLRDRFMVPGLLFIDTPGHHAFTTLRSRGGALADLAIVVVDINEGFKPQTYESLQIL
CCCHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCEEEEEEEEEECCCCCCCCHHHHHHHH
KRFKTPFVVVANKIDRIGGWVSQKDMPFAATFKKQSSDVQARLETKLYEVIGELYNQGFA
HHHCCCEEEEEHHHHHHCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
AERYDRVTNFQKTLGVVPVSAFTGEGIPDVLMVLLGLAQKFLEANLQYSAKGPGVGTVLE
HHHHHHHHHHHHHHCCEEEHHHCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEE
VKEEKGLGATLDIILYDGTLKKGDTVVIGSLGEPIRTKVRALLKPRELSEIRYESKFQQV
EECCCCCCCEEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
SKVTAAAGVKISAPGLEGALAGSPIRVATEDNLEEIASQVKSEIDEVRIDTGSVGIMIKA
HHHHHHCCCEEECCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHEEECCCCEEEEEEE
DTLGSLEALVHEFQKDEVPIRKAEVGDISHRDAVEASTVEDPLYSVIIGFNVKVHPDARD
CCCCHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCHHHHCCCHHEEEEECEEEECCCHHH
FLQESSVKVFTSDVIYRLVEDYQKYVKEQQEKAEKKIFETIIRPGKFKILPGCVFRQSKP
HHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHCCCCCC
AVVGVRVLGGVVRTNTDVMLENGNVVGKIKGLQSEGENIPSAKVGKEVAMAIEGATVGRQ
CEEEHHHHCCHHCCCCEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHEECCCHHCCC
IKEEDVLYVNVPERHAKVLEHEIYESLSTDEKETLDIFLTLKRKDNPFWAK
CCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCC
>Mature Secondary Structure 
TDKKNLRTPIVCVMGHVDHGKTTLLDKIRGTAIVSGEAGAITQHIGATEVPIDVIIDKL
CCCCCCCCCEEEEEECCCCCHHHHHHHHCCCEEECCCCCCHHHHCCCCCCCHHHHHHCC
GDPRLRDRFMVPGLLFIDTPGHHAFTTLRSRGGALADLAIVVVDINEGFKPQTYESLQIL
CCCHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCEEEEEEEEEECCCCCCCCHHHHHHHH
KRFKTPFVVVANKIDRIGGWVSQKDMPFAATFKKQSSDVQARLETKLYEVIGELYNQGFA
HHHCCCEEEEEHHHHHHCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
AERYDRVTNFQKTLGVVPVSAFTGEGIPDVLMVLLGLAQKFLEANLQYSAKGPGVGTVLE
HHHHHHHHHHHHHHCCEEEHHHCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEE
VKEEKGLGATLDIILYDGTLKKGDTVVIGSLGEPIRTKVRALLKPRELSEIRYESKFQQV
EECCCCCCCEEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
SKVTAAAGVKISAPGLEGALAGSPIRVATEDNLEEIASQVKSEIDEVRIDTGSVGIMIKA
HHHHHHCCCEEECCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHEEECCCCEEEEEEE
DTLGSLEALVHEFQKDEVPIRKAEVGDISHRDAVEASTVEDPLYSVIIGFNVKVHPDARD
CCCCHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCHHHHCCCHHEEEEECEEEECCCHHH
FLQESSVKVFTSDVIYRLVEDYQKYVKEQQEKAEKKIFETIIRPGKFKILPGCVFRQSKP
HHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHCCCCCC
AVVGVRVLGGVVRTNTDVMLENGNVVGKIKGLQSEGENIPSAKVGKEVAMAIEGATVGRQ
CEEEHHHHCCHHCCCCEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHEECCCHHCCC
IKEEDVLYVNVPERHAKVLEHEIYESLSTDEKETLDIFLTLKRKDNPFWAK
CCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]